{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:55:32Z","timestamp":1787504132381,"version":"build-2736575974"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy &amp; Behavior"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.yebeh.2021.107839","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T09:45:23Z","timestamp":1613900723000},"page":"107839","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Temporal lobe dysfunction in late-onset epilepsy of unknown origin"],"prefix":"10.1016","volume":"117","author":[{"given":"Jacopo C.","family":"DiFrancesco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Isella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Licciardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Crivellaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Musarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Guerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Salvadori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Chipi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Calvello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Ferrarese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2021.107839_b0005","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1528-1157.1993.tb02586.x","article-title":"Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935\u20131984","volume":"34","author":"Hauser","year":"1993","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0010","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1159\/000493484","article-title":"Aging and the epidemiology of epilepsy","volume":"51","author":"Beghi","year":"2018","journal-title":"Neuroepidemiology"},{"key":"10.1016\/j.yebeh.2021.107839_b0015","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.eplepsyres.2017.12.016","article-title":"Epilepsy in an elderly population: Classification, etiology and drug resistance","volume":"140","author":"Hern\u00e1ndez-Ronquillo","year":"2018","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2021.107839_b0020","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.eplepsyres.2005.07.016","article-title":"Epidemiological and medical aspects of epilepsy in the elderly","volume":"68","author":"Cloyd","year":"2006","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2021.107839_b0025","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S1474-4422(17)30044-3","article-title":"Epileptic activity in Alzheimer's disease: causes and clinical relevance","volume":"16","author":"Vossel","year":"2017","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0030","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/ana.24794","article-title":"Incidence and impact of subclinical epileptiform activity in Alzheimer's disease","volume":"80","author":"Vossel","year":"2016","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0035","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1001\/jamaneurol.2013.136","article-title":"Seizures and epileptiform activity in the early stages of Alzheimer disease","volume":"70","author":"Vossel","year":"2013","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0040","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.3233\/JAD-170392","article-title":"Adult-onset epilepsy in presymptomatic Alzheimer's disease: a retrospective study","volume":"60","author":"DiFrancesco","year":"2017","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.yebeh.2021.107839_b0045","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.neurobiolaging.2016.08.025","article-title":"Epilepsy, amyloid-\u03b2, and D1 dopamine receptors: a possible pathogenetic link?","volume":"48","author":"Costa","year":"2016","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.yebeh.2021.107839_b0050","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3389\/fneur.2020.00199","article-title":"Late-onset epilepsy with unknown etiology: A pilot study on neuropsychological profile, cerebrospinal fluid biomarkers, and quantitative EEG characteristics","volume":"11","author":"Nardi Cesarini","year":"2020","journal-title":"Front Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0055","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.neurobiolaging.2018.09.006","article-title":"Alzheimer's disease and late-onset epilepsy of unknown origin: two faces of beta amyloid pathology","volume":"73","author":"Costa","year":"2019","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.yebeh.2021.107839_b0060","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.yebeh.2018.05.043","article-title":"Nonlesional late-onset epilepsy: semiology, EEG, cerebrospinal fluid, and seizure outcome characteristics","volume":"91","author":"S\u00fc\u00dfe","year":"2019","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2021.107839_b0065","doi-asserted-by":"crossref","first-page":"106478","DOI":"10.1016\/j.yebeh.2019.106478","article-title":"Late-onset unexplained epilepsy: What are we missing?","volume":"99","author":"Sarkis","year":"2019","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2021.107839_b0070","first-page":"178","article-title":"Brain 18F-FDG-PET: utility in the diagnosis of dementia and epilepsy","volume":"22","author":"Lotan","year":"2020","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.yebeh.2021.107839_b0075","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/WCO.0000000000000527","article-title":"PET and ictal SPECT can be helpful for localizing epileptic foci","volume":"31","author":"von Oertzen","year":"2018","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0080","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/epi.13699","article-title":"MRI-negative temporal lobe epilepsy-What do we know?","volume":"58","author":"Muhlhofer","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0085","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/WCO.0b013e328042baf6","article-title":"The use of SPECT and PET in routine clinical practice in epilepsy","volume":"20","author":"Van Paesschen","year":"2007","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0090","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/epi.12962","article-title":"Indications and expectations for neuropsychological assessment in routine epilepsy care: Report of the ILAE Neuropsychology Task Force, Diagnostic Methods Commission, 2013\u20132017","volume":"56","author":"Wilson","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0095","doi-asserted-by":"crossref","unstructured":"Vogt VL, \u00c4iki\u00e4 M, Del Barrio A, Boon P, Borb\u00e9ly C, Bran E, et al. Current standards of neuropsychological assessment in epilepsy surgery centers across Europe. Epilepsia 2017;58: 343\u201355.","DOI":"10.1111\/epi.13646"},{"key":"10.1016\/j.yebeh.2021.107839_b0100","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1111\/epi.13670","article-title":"Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology","volume":"58","author":"Fisher","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0105","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.yebeh.2019.04.015","article-title":"Temporal lobe epilepsy is associated with distinct cognitive phenotypes","volume":"96","author":"Elverman","year":"2019","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2021.107839_b0110","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1212\/01.WNL.0000125186.04867.34","article-title":"The nature and course of neuropsychological morbidity in chronic temporal lobe epilepsy","volume":"62","author":"Oyegbile","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2021.107839_b0115","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.jalz.2011.03.008","article-title":"The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease","volume":"7","author":"Albert","year":"2011","journal-title":"Alzheimers Dement"},{"key":"10.1016\/j.yebeh.2021.107839_b0120","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1001\/archpsyc.1983.01790060110016","article-title":"The Mini-Mental State Examination","volume":"40","author":"Folstein","year":"1983","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.yebeh.2021.107839_b0125","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1007\/s10072-012-1130-x","article-title":"Forward and backward span for verbal and visuo-spatial data: standardization and normative data from an Italian adult population","volume":"34","author":"Monaco","year":"2013","journal-title":"Neurol Sci"},{"key":"10.1016\/j.yebeh.2021.107839_b0130","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1080\/13854046.2012.704073","article-title":"Using the Rey Auditory Verbal Learning Test (RAVLT) to differentiate alzheimer's dementia and behavioural variant fronto-temporal dementia","volume":"26","author":"Ricci","year":"2012","journal-title":"Clin Neuropsychol"},{"key":"10.1016\/j.yebeh.2021.107839_b0135","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1177\/107319119900600204","article-title":"Norms for letter and category fluency: demographic corrections for age, education, and ethnicity","volume":"6","author":"Gladsjo","year":"1999","journal-title":"Assessment"},{"key":"10.1016\/j.yebeh.2021.107839_b0140","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1007\/s10072-005-0443-4","article-title":"The Frontal Assessment Battery (FAB): normative values in an Italian population sample","volume":"26","author":"Appollonio","year":"2005","journal-title":"Neurol Sci"},{"key":"10.1016\/j.yebeh.2021.107839_b0145","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1159\/000117297","article-title":"The Mental Deterioration Battery: normative data, diagnostic reliability and qualitative analyses of cognitive impairment. The Group for the Standardization of the Mental Deterioration Battery","volume":"36","author":"Carlesimo","year":"1996","journal-title":"Eur Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0150","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s100720200003","article-title":"Rey-Osterrieth complex figure: normative values in an Italian population sample","volume":"22","author":"Caffarra","year":"2002","journal-title":"Neurol Sci"},{"key":"10.1016\/j.yebeh.2021.107839_b0155","unstructured":"Nocentini U, Giordano A, Di Vincenzo S, Panella M, Pasqualetti P. The Symbol Digit Modalities Test - Oral version: Italian normative data. Funct Neurol 2006;21: 93-6."},{"key":"10.1016\/j.yebeh.2021.107839_b0160","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.nicl.2014.10.009","article-title":"Validation of an optimized SPM procedure for FDG-PET in dementia diagnosis in a clinical setting","volume":"6","author":"Perani","year":"2014","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.yebeh.2021.107839_b0165","doi-asserted-by":"crossref","unstructured":"Gallivanone F, Della Rosa PA, Perani D, Gilardi MC, Castiglioni I, Consortium E-P. The impact of different 18FDG PET healthy subject scans for comparison with single patient in SPM analysis. Q J Nucl Med Mol Imaging 2017;61: 115-132.","DOI":"10.23736\/S1824-4785.16.02749-7"},{"key":"10.1016\/j.yebeh.2021.107839_b0170","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s13311-014-0263-4","article-title":"Origins of temporal lobe epilepsy: febrile seizures and febrile status epilepticus","volume":"11","author":"Patterson","year":"2014","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.yebeh.2021.107839_b0175","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1111\/epi.12220","article-title":"International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods","volume":"54","author":"Bl\u00fcmcke","year":"2013","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0180","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1528-1167.2006.00462.x","article-title":"EEG features in idiopathic generalized epilepsy: clues to diagnosis","volume":"47","author":"Betting","year":"2006","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0185","doi-asserted-by":"crossref","unstructured":"Sinha N, Peternell N, Schroeder GM, de Tisi J, Vos SB, Winston GP, Duncan JS, Wang Y, Taylor PN. Focal to bilateral tonic-clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy. Epilepsia 2021.","DOI":"10.1111\/epi.16819"},{"key":"10.1016\/j.yebeh.2021.107839_b0190","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1001\/jama.2012.220","article-title":"Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial","volume":"307","author":"Engel","year":"2012","journal-title":"JAMA"},{"key":"10.1016\/j.yebeh.2021.107839_b0195","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.seizure.2013.06.005","article-title":"Clinical characteristics and treatment responses in new-onset epilepsy in the elderly","volume":"22","author":"Tanaka","year":"2013","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2021.107839_b0200","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.eplepsyres.2016.08.023","article-title":"Outcome of initial antiepileptic drug treatment in elderly patients with newly diagnosed epilepsy","volume":"127","author":"Bruun","year":"2016","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2021.107839_b0205","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1007\/s00259-019-04356-x","article-title":"The predictive value of hypometabolism in focal epilepsy: a prospective study in surgical candidates","volume":"46","author":"Tom\u00e1s","year":"2019","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.yebeh.2021.107839_b0210","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1212\/WNL.54.9.1811","article-title":"Significance of interictal bilateral temporal hypometabolism in temporal lobe epilepsy","volume":"54","author":"Koutroumanidis","year":"2000","journal-title":"Neurology"},{"issue":"Pt 12","key":"10.1016\/j.yebeh.2021.107839_b0215","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1093\/brain\/120.12.2283","article-title":"Prefrontal asymmetric interictal glucose hypometabolism and cognitive impairment in patients with temporal lobe epilepsy","volume":"120","author":"Jokeit","year":"1997","journal-title":"Brain"},{"key":"10.1016\/j.yebeh.2021.107839_b0220","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/ana.10087","article-title":"Insular cortex involvement in mesiotemporal lobe epilepsy: a positron emission tomography study","volume":"51","author":"Bouilleret","year":"2002","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0225","first-page":"1964","article-title":"Ipsilateral and contralateral thalamic hypometabolism as a predictor of outcome after temporal lobectomy for seizures","volume":"41","author":"Newberg","year":"2000","journal-title":"J Nucl Med"},{"key":"10.1016\/j.yebeh.2021.107839_b0230","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.yebeh.2017.12.022","article-title":"The relationship between structural MRI, FDG-PET, and memory in temporal lobe epilepsy: preliminary results","volume":"80","author":"Berger","year":"2018","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2021.107839_b0235","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1111\/epi.13377","article-title":"Determinants of brain metabolism changes in mesial temporal lobe epilepsy","volume":"57","author":"Chassoux","year":"2016","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0240","doi-asserted-by":"crossref","first-page":"106948","DOI":"10.1016\/j.yebeh.2020.106948","article-title":"Metabolic correlates of cognitive impairment in mesial temporal lobe epilepsy","volume":"105","author":"Laurent","year":"2020","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2021.107839_b0245","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3389\/fneur.2017.00360","article-title":"Recurrent epileptic auras as a presenting symptom of Alzheimer's disease","volume":"8","author":"Sarkis","year":"2017","journal-title":"Front Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0250","doi-asserted-by":"crossref","first-page":"453","DOI":"10.3389\/fneur.2017.00453","article-title":"Automated online quantification method for","volume":"8","author":"Mendes Coelho","year":"2017","journal-title":"Front Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0255","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1111\/epi.16528","article-title":"Cognitive phenotypes in temporal lobe epilepsy utilizing data- and clinically driven approaches: Moving toward a new taxonomy","volume":"61","author":"Reyes","year":"2020","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0260","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.eplepsyres.2011.10.009","article-title":"Frontal lobe function in temporal lobe epilepsy","volume":"98","author":"Stretton","year":"2012","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2021.107839_b0265","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/nrneurol.2011.3","article-title":"The neurobiology of cognitive disorders in temporal lobe epilepsy","volume":"7","author":"Bell","year":"2011","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.yebeh.2021.107839_b0270","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.exger.2015.11.016","article-title":"Temporal lobe in human aging: A quantitative protein profiling study of samples from Chinese Human Brain Bank","volume":"73","author":"Xu","year":"2016","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.yebeh.2021.107839_b0275","doi-asserted-by":"crossref","unstructured":"Guo CC, Gorno-Tempini ML, Gesierich B, Henry M, Trujillo A, Shany-Ur T, Jovicich J, Robinson SD, Kramer JH, Rankin KP, Miller BL, Seeley WW. Anterior temporal lobe degeneration produces widespread network-driven dysfunction. Brain 2013;136: 2979-91.","DOI":"10.1093\/brain\/awt222"},{"issue":"Suppl 2","key":"10.1016\/j.yebeh.2021.107839_b0280","first-page":"S48","article-title":"Antiepileptic drugs and cerebral glucose metabolism","volume":"29","author":"Theodore","year":"1988","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2021.107839_b0285","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0140-6736(00)03600-X","article-title":"Neuropsychological effects of epilepsy and antiepileptic drugs","volume":"357","author":"Kwan","year":"2001","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.yebeh.2021.107839_b0290","doi-asserted-by":"crossref","first-page":"593","DOI":"10.2165\/00003495-200262040-00004","article-title":"Effect of antiepileptic drugs on cognitive function in individuals with epilepsy: a comparative review of newer versus older agents","volume":"62","author":"Brunbech","year":"2002","journal-title":"Drugs"},{"key":"10.1016\/j.yebeh.2021.107839_b0295","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s11910-016-0696-8","article-title":"Treatment of epilepsy in the elderly","volume":"16","author":"Motika","year":"2016","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.yebeh.2021.107839_b0300","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.eplepsyres.2015.11.009","article-title":"Antiepileptic drug use and epileptic seizures in nursing home residents in the Province of Pavia, Italy: A reappraisal 12 years after a first survey","volume":"119","author":"Galimberti","year":"2016","journal-title":"Epilepsy Res"}],"container-title":["Epilepsy &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505021000731?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505021000731?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:37:48Z","timestamp":1761503868000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505021000731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":60,"alternative-id":["S1525505021000731"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2021.107839","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Temporal lobe dysfunction in late-onset epilepsy of unknown origin","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2021.107839","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"107839"}}