{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T05:55:08Z","timestamp":1793253308922,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T00:00:00Z","timestamp":1675382400000},"content-version":"am","delay-in-days":339,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["2 UL1 TR000445-06"],"award-info":[{"award-number":["2 UL1 TR000445-06"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R56MH120736"],"award-info":[{"award-number":["R56MH120736"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01MH118223"],"award-info":[{"award-number":["R01MH118223"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01MH113362"],"award-info":[{"award-number":["R01MH113362"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS102371"],"award-info":[{"award-number":["R01NS102371"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01NS105746"],"award-info":[{"award-number":["R01NS105746"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","award":["UL1 RR024975-01"],"award-info":[{"award-number":["UL1 RR024975-01"]}],"id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.yebeh.2022.108582","type":"journal-article","created":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T20:34:28Z","timestamp":1643834068000},"page":"108582","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Functional seizures are associated with cerebrovascular disease and functional stroke is more common in patients with functional seizures than epileptic seizures"],"prefix":"10.1016","volume":"128","author":[{"given":"Jonah","family":"Fox","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Slavina B.","family":"Goleva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin F.","family":"Haas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea K.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2022.108582_b0005","doi-asserted-by":"crossref","unstructured":"American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed. (DSM-5). Washington: American Psychiatric Association; 2013.","DOI":"10.1176\/appi.books.9780890425596"},{"issue":"9","key":"10.1016\/j.yebeh.2022.108582_b0010","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/j.clineuro.2010.05.011","article-title":"Who is referred to neurology clinics?\u2013the diagnoses made in 3781 new patients","volume":"112","author":"Stone","year":"2010","journal-title":"Clin Neurol Neurosurg"},{"issue":"5","key":"10.1016\/j.yebeh.2022.108582_b0015","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1111\/ene.14728","article-title":"Functional neurological disorders presenting as emergencies to secondary care","volume":"28","author":"Beharry","year":"2021","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.yebeh.2022.108582_b0020","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1136\/jnnp-2020-323953","article-title":"Decade of progress in motor functional neurological disorder: continuing the momentum","volume":"92","author":"Perez","year":"2021","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"12","key":"10.1016\/j.yebeh.2022.108582_b0025","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.27920","article-title":"Epidemiology of functional seizures among adults treated at a university hospital","volume":"3","author":"Goleva","year":"2020","journal-title":"JAMA Network Open"},{"key":"10.1016\/j.yebeh.2022.108582_b0030","doi-asserted-by":"crossref","first-page":"3473","DOI":"10.1093\/brain\/awz292","article-title":"Polygenic burden in focal and generalized epilepsies","volume":"142","author":"Leu","year":"2019","journal-title":"Brain"},{"key":"10.1016\/j.yebeh.2022.108582_b0035","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/epi4.12460","article-title":"Newly diagnosed seizures assessed at two established first seizure clinics: Clinic characteristics, investigations, and findings over 11 years","volume":"6","author":"McIntosh","year":"2021","journal-title":"Epilepsia Open"},{"key":"10.1016\/j.yebeh.2022.108582_b0040","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/0140-6736(90)92960-P","article-title":"National General Practice Study of Epilepsy: recurrence after a first seizure","volume":"336","author":"Hart","year":"1990","journal-title":"Lancet"},{"key":"10.1016\/j.yebeh.2022.108582_b0045","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S1474-4422(15)00248-3","article-title":"Development of epilepsy after ischaemic stroke","volume":"15","author":"Pitk\u00e4nen","year":"2016","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.yebeh.2022.108582_b0050","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1684\/epd.2019.1107","article-title":"The aetiology of psychogenic non-epileptic seizures: risk factors and comorbidities","volume":"21","author":"Popkirov","year":"2019","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.yebeh.2022.108582_b0055","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.seizure.2018.04.009","article-title":"Scared or scarred: could \u2018dissociogenic\u2019lesions predispose to nonepileptic seizures after head trauma?","volume":"58","author":"Popkirov","year":"2018","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2022.108582_b0060","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1080\/026990598122773","article-title":"Predictors of acute stress following mild traumatic brain injury","volume":"12","author":"Harvey","year":"1998","journal-title":"Brain Inj"},{"key":"10.1016\/j.yebeh.2022.108582_b0065","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2018.00890","article-title":"Association between anxiety, depression, and post-traumatic stress disorder and outcomes after ischemic stroke","volume":"9","author":"Stein","year":"2018","journal-title":"Front Neurol"},{"key":"10.1016\/j.yebeh.2022.108582_b0070","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.cpr.2016.06.003","article-title":"Towards an integrative theory of psychogenic non-epileptic seizures (PNES)","volume":"47","author":"Brown","year":"2016","journal-title":"Clin Psychol Rev"},{"key":"10.1016\/j.yebeh.2022.108582_b0075","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.seizure.2016.10.029","article-title":"Understanding psychogenic nonepileptic seizures\u2014phenomenology, semiology and the integrative cognitive model","volume":"44","author":"Reuber","year":"2017","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2022.108582_b0080","doi-asserted-by":"crossref","first-page":"l1255","DOI":"10.1136\/bmj.l1255","article-title":"Stress related disorders and risk of cardiovascular disease: population based, sibling controlled cohort study","volume":"365","author":"Song","year":"2019","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.yebeh.2022.108582_b0085","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1038\/nrcardio.2017.189","article-title":"Effects of stress on the development and progression of cardiovascular disease","volume":"15","author":"Kivim\u00e4ki","year":"2018","journal-title":"Nat Rev Cardiol"},{"issue":"11","key":"10.1016\/j.yebeh.2022.108582_b0090","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1161\/STROKEAHA.110.607705","article-title":"Stress worsens endothelial function and ischemic stroke via glucocorticoids","volume":"42","author":"Balkaya","year":"2011","journal-title":"Stroke"},{"issue":"Supplement_2","key":"10.1016\/j.yebeh.2022.108582_b0095","doi-asserted-by":"crossref","first-page":"17180","DOI":"10.1073\/pnas.1121254109","article-title":"Brain on stress: how the social environment gets under the skin","volume":"109","author":"McEwen","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"8","key":"10.1016\/j.yebeh.2022.108582_b0100","doi-asserted-by":"crossref","first-page":"e356","DOI":"10.1016\/S2468-2667(17)30118-4","article-title":"The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis","volume":"2","author":"Hughes","year":"2017","journal-title":"Lancet Public Health"},{"issue":"6","key":"10.1016\/j.yebeh.2022.108582_b0105","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1017\/S1092852920001789","article-title":"A framework for understanding the pathophysiology of functional neurological disorder","volume":"26","author":"Drane","year":"2021","journal-title":"CNS Spectr"},{"key":"10.1016\/j.yebeh.2022.108582_b0110","doi-asserted-by":"crossref","first-page":"101798","DOI":"10.1016\/j.nicl.2019.101798","article-title":"Structural alterations in functional neurological disorder and related conditions: a software and hardware problem?","volume":"22","author":"B\u00e8gue","year":"2019","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.yebeh.2022.108582_b0115","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1186\/s12888-016-0890-x","article-title":"Neural correlates of conversion disorder: overview and meta-analysis of neuroimaging studies on motor conversion disorder","volume":"16","author":"Boeckle","year":"2016","journal-title":"BMC Psychiatry"},{"issue":"1","key":"10.1016\/j.yebeh.2022.108582_b0120","doi-asserted-by":"crossref","first-page":"e40","DOI":"10.1176\/appi.neuropsych.13070170","article-title":"A neural circuit framework for somatosensory amplification in somatoform disorders","volume":"27","author":"Perez","year":"2015","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.yebeh.2022.108582_b0125","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.nicl.2016.04.001","article-title":"Neural correlates of somatoform disorders from a meta-analytic perspective on neuroimaging studies","volume":"11","author":"Boeckle","year":"2016","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.yebeh.2022.108582_b0130","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.yebeh.2018.09.008","article-title":"The application of artificial intelligence to understand the pathophysiological basis of psychogenic nonepileptic seizures","volume":"87","author":"Vasta","year":"2018","journal-title":"Epilepsy Behav"},{"issue":"2","key":"10.1016\/j.yebeh.2022.108582_b0135","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1007\/s11065-019-09398-4","article-title":"The role of the amygdala and the ventromedial prefrontal cortex in emotional regulation: implications for post-traumatic stress disorder","volume":"29","author":"Andrewes","year":"2019","journal-title":"Neuropsychol Rev"},{"key":"10.1016\/j.yebeh.2022.108582_b0140","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.nicl.2017.04.004","article-title":"Symptom-specific amygdala hyperactivity modulates motor control network in conversion disorder","volume":"15","author":"Hassa","year":"2017","journal-title":"NeuroImage Clin"},{"issue":"2","key":"10.1016\/j.yebeh.2022.108582_b0145","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.pain.2007.10.003","article-title":"Altered cerebral response to noxious heat stimulation in patients with somatoform pain disorder","volume":"137","author":"G\u00fcndel","year":"2008","journal-title":"PAIN\u00ae"},{"key":"10.1016\/j.yebeh.2022.108582_b0150","doi-asserted-by":"crossref","first-page":"102247","DOI":"10.1016\/j.nicl.2020.102247","article-title":"Amygdala hyperreactivity to faces conditioned with a social-evaluative meaning\u2013 a multiplex, multigenerational fMRI study on social anxiety endophenotypes","volume":"26","author":"Bas-Hoogendam","year":"2020","journal-title":"NeuroImage Clin"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505022000312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505022000312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:08:26Z","timestamp":1778616506000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505022000312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":30,"alternative-id":["S1525505022000312"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2022.108582","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional seizures are associated with cerebrovascular disease and functional stroke is more common in patients with functional seizures than epileptic seizures","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2022.108582","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"108582"}}