{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T04:07:30Z","timestamp":1769573250064,"version":"3.49.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003243","name":"Ministerstvo Zdravotnictv\u00ed Cesk\u00e9 Republiky","doi-asserted-by":"publisher","award":["NV19-04-00369"],"award-info":[{"award-number":["NV19-04-00369"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.yebeh.2023.109204","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T06:38:47Z","timestamp":1682059127000},"page":"109204","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Neurocognitive profile in patients with idiopathic generalized epilepsies: Differences between patients, their biological siblings, and healthy controls"],"prefix":"10.1016","volume":"142","author":[{"given":"A.","family":"Javurkova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zivnustka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Brezinova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Raudenska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Zarubova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Marusic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.yebeh.2023.109204_b0005","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.tins.2006.05.009","article-title":"Human epilepsies: interaction of genetic and acquired factors","volume":"29","author":"Berkovic","year":"2006","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.yebeh.2023.109204_b0010","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.neubiorev.2014.02.012","article-title":"Cognitive functioning in idiopathic generalised epilepsies: a systematic review and meta-analysis","volume":"43","author":"Loughman","year":"2014","journal-title":"Neurosci Biobehav Rev"},{"issue":"11","key":"10.1016\/j.yebeh.2023.109204_b0015","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S1474-4422(04)00906-8","article-title":"Chronic epilepsy and cognition","volume":"3","author":"Elger","year":"2004","journal-title":"Lancet Neurol"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109204_b0020","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.neubiorev.2005.06.004","article-title":"Idiopathic epileptic syndromes and cognition","volume":"30","author":"Hommet","year":"2006","journal-title":"Neurosci Biobehav Rev"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109204_b0025","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1111\/epi.12604","article-title":"Impaired cognitive function in idiopathic generalized epilepsy and unaffected family members: an epilepsy endophenotype","volume":"55","author":"Chowdhury","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2023.109204_b0030","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.yebeh.2018.10.007","article-title":"The cognitive phenotype of idiopathic generalized epilepsy","volume":"89","author":"Abarrategui","year":"2018","journal-title":"Epilepsy Behav"},{"issue":"7","key":"10.1016\/j.yebeh.2023.109204_b0035","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1136\/jnnp.2005.086918","article-title":"Idiopathic generalised epilepsy: a pilot study of memory and neuronal dysfunction in the temporal lobes, assessed by magnetic resonance spectroscopy","volume":"77","author":"Dickson","year":"2006","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109204_b0040","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1017\/S0012162205000228","article-title":"Cognitive function in idiopathic generalized epilepsy of childhood","volume":"47","author":"Henkin","year":"2005","journal-title":"Dev Med Child Neurol"},{"issue":"12","key":"10.1016\/j.yebeh.2023.109204_b0045","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1111\/j.1528-1167.2012.03719.x","article-title":"Accelerated long-term forgetting in children with idiopathic generalized epilepsy","volume":"53","author":"Gascoigne","year":"2012","journal-title":"Epilepsia"},{"issue":"3\u20134","key":"10.1016\/j.yebeh.2023.109204_b0050","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1177\/0972753120968751","article-title":"The Impact of Idiopathic Generalized Epilepsy on Executive Functions","volume":"27","author":"Koganti","year":"2020","journal-title":"Ann Neurosci"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109204_b0055","first-page":"14","article-title":"Juvenile myoclonic epilepsy (JME): neuropsychological profile and related factors with cognitive dysfunction","volume":"9","author":"Motamedi","year":"2014","journal-title":"Iran J Psychiatry"},{"key":"10.1016\/j.yebeh.2023.109204_b0060","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.yebeh.2014.04.027","article-title":"A comprehensive neuropsychological description of cognition in drug-refractory juvenile myoclonic epilepsy","volume":"36","author":"Thomas","year":"2014","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2023.109204_b0065","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.yebeh.2018.06.009","article-title":"Frontal lobe cognitive functions and electroencephalographic features in juvenile myoclonic epilepsy","volume":"86","author":"Sezikli","year":"2018","journal-title":"Epilepsy Behav"},{"issue":"8","key":"10.1016\/j.yebeh.2023.109204_b0070","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1111\/epi.13061","article-title":"Neuropsychological profiles of patients with juvenile myoclonic epilepsy and their siblings: an extended study","volume":"56","author":"Iqbal","year":"2015","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2023.109204_b0075","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.seizure.2016.06.002","article-title":"Cognitive performance in juvenile myoclonic epilepsy patients with specific endophenotypes","volume":"40","author":"de Carvalho","year":"2016","journal-title":"Seizure"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109204_b0080","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.yebeh.2013.06.034","article-title":"Hippocampal atrophy and memory dysfunction in patients with juvenile myoclonic epilepsy","volume":"29","author":"Lin","year":"2013","journal-title":"Epilepsy Behav"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109204_b0085","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/j.yebeh.2010.05.010","article-title":"Dysfunction of executive and related processes in childhood absence epilepsy","volume":"18","author":"Conant","year":"2010","journal-title":"Epilepsy Behav"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109204_b0090","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.yebeh.2008.12.025","article-title":"Neuropsychological profiles of patients with juvenile myoclonic epilepsy and their siblings: a preliminary controlled experimental video-EEG case series","volume":"14","author":"Iqbal","year":"2009","journal-title":"Epilepsy Behav"},{"issue":"24","key":"10.1016\/j.yebeh.2023.109204_b0095","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1212\/WNL.0b013e318202010a","article-title":"Prospective memory in patients with juvenile myoclonic epilepsy and their healthy siblings","volume":"75","author":"Wandschneider","year":"2010","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109204_b0100","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1111\/j.1528-1157.1992.tb01767.x","article-title":"Determinants of IQ Profile in Children Generalized Epilepsy","volume":"33","author":"Singhi","year":"1992","journal-title":"Epilepsia"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109204_b0105","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1076\/jcen.24.3.311.985","article-title":"Familial association of neuropsychological traits in patients with generalized and partial seizure disorders","volume":"24","author":"Levav","year":"2002","journal-title":"J Clin Exp Neuropsychol"},{"key":"10.1016\/j.yebeh.2023.109204_b0110","unstructured":"Defined Daily Dose (DDD). Who.int, https:\/\/www.who.int\/toolkits\/atc-ddd-toolkit\/about-ddd; 2022 [accessed 12 January 2022]."},{"issue":"suppl 1","key":"10.1016\/j.yebeh.2023.109204_b0115","doi-asserted-by":"crossref","first-page":"i45","DOI":"10.1136\/jnnp.2004.060467","article-title":"Depression and anxiety in epilepsy","volume":"76","author":"Jackson","year":"2005","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109204_b0120","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1002\/hbm.21286","article-title":"Resting state basal ganglia network in idiopathic generalized epilepsy","volume":"33","author":"Luo","year":"2012","journal-title":"Hum Brain Mapp"},{"issue":"7","key":"10.1016\/j.yebeh.2023.109204_b0125","doi-asserted-by":"crossref","first-page":"3924","DOI":"10.1007\/s00330-020-06674-3","article-title":"Cerebello-cerebral connectivity in idiopathic generalized epilepsy","volume":"30","author":"Jiang","year":"2020","journal-title":"Eur Radiol"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109204_b0130","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1177\/1756285611417920","article-title":"The cognitive impact of antiepileptic drugs","volume":"4","author":"Eddy","year":"2011","journal-title":"Ther Adv Neurol Disord"},{"key":"10.1016\/j.yebeh.2023.109204_b0135","series-title":"Neuropsychological assessment of patients with epilepsy. InHandbook on the neuropsychology of epilepsy","first-page":"1","author":"Barr","year":"2015"},{"issue":"12","key":"10.1016\/j.yebeh.2023.109204_b0140","doi-asserted-by":"crossref","first-page":"2156","DOI":"10.1111\/j.1528-1167.2012.03706.x","article-title":"Neurocognitive profiles in children with epilepsy","volume":"53","author":"Kernan","year":"2012","journal-title":"Epilepsia"},{"issue":"12","key":"10.1016\/j.yebeh.2023.109204_b0145","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1111\/j.1528-1167.2012.03723.x","article-title":"The prognosis of idiopathic generalized epilepsy","volume":"53","author":"Seneviratne","year":"2012","journal-title":"Epilepsia"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109204_b0150","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1007\/s11065-019-09419-2","article-title":"Towards a better understanding of cognitive deficits in absence epilepsy: a systematic review and meta-analysis","volume":"29","author":"Wald","year":"2019","journal-title":"Neuropsychol Rev"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109204_b0155","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1528-1167.2007.01482.x","article-title":"Frontal cognitive dysfunction in juvenile myoclonic epilepsy","volume":"49","author":"Piazzini","year":"2008","journal-title":"Epilepsia"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109204_b0160","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.yebeh.2006.11.012","article-title":"Neuropsychological profile of patients with juvenile myoclonic epilepsy: a controlled study of 50 patients","volume":"10","author":"Pascalicchio","year":"2007","journal-title":"Epilepsy Behav"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109204_b0165","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.yebeh.2012.10.002","article-title":"Juvenile myoclonic epilepsy: the impact of clinical variables and psychiatric disorders on executive profile assessed with a comprehensive neuropsychological battery","volume":"25","author":"Moschetta","year":"2012","journal-title":"Epilepsy Behav"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109204_b0170","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3988\/jcn.2007.3.2.86","article-title":"Cognitive impairment in juvenile myoclonic epilepsy","volume":"3","author":"Kim","year":"2007","journal-title":"J Clin Neurol"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109204_b0175","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.yebeh.2004.01.007","article-title":"Cognitive function in juvenile myoclonic epilepsy","volume":"5","author":"Sonmez","year":"2004","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2023.109204_b0180","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.brainres.2010.12.034","article-title":"Altered resting state networks in epileptic patients with generalized tonic\u2013clonic seizures","volume":"1374","author":"Wang","year":"2011","journal-title":"Brain Res"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109204_b0185","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.yebeh.2008.01.006","article-title":"Psychiatric comorbidity in adult patients with idiopathic generalized epilepsy","volume":"13","author":"Akanuma","year":"2008","journal-title":"Epilepsy Behav"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109204_b0190","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.yebeh.2008.08.014","article-title":"Cognitive function, mood, behavioral aspects, and personality traits of adult males with idiopathic epilepsy","volume":"14","author":"Shehata","year":"2009","journal-title":"Epilepsy Behav"},{"issue":"8","key":"10.1016\/j.yebeh.2023.109204_b0195","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/j.eplepsyres.2014.06.002","article-title":"Self-rated and assessed cognitive functions in epilepsy: impact on quality of life","volume":"108","author":"Giovagnoli","year":"2014","journal-title":"Epilepsy Res"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109204_b0200","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.yebeh.2004.08.019","article-title":"Determinants of quality of life in epilepsy","volume":"5","author":"Loring","year":"2004","journal-title":"Epilepsy Behav"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109204_b0205","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3390\/medicina47060044","article-title":"Executive functions in adolescents with idiopathic generalized epilepsy","volume":"47","author":"Gel\u017einien\u0117","year":"2011","journal-title":"Medicina"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109204_b0210","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s11065-007-9042-x","article-title":"Cognitive progression in epilepsy","volume":"17","author":"Seidenberg","year":"2007","journal-title":"Neuropsychol Rev"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505023001233?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505023001233?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:50:33Z","timestamp":1761504633000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505023001233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":42,"alternative-id":["S1525505023001233"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2023.109204","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurocognitive profile in patients with idiopathic generalized epilepsies: Differences between patients, their biological siblings, and healthy controls","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2023.109204","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109204"}}