{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:43:28Z","timestamp":1785768208171,"version":"3.56.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004835","name":"Zhejiang University","doi-asserted-by":"publisher","award":["2021KYY600403-0001"],"award-info":[{"award-number":["2021KYY600403-0001"]}],"id":[{"id":"10.13039\/501100004835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004835","name":"Zhejiang University","doi-asserted-by":"publisher","award":["2021ZD0200405"],"award-info":[{"award-number":["2021ZD0200405"]}],"id":[{"id":"10.13039\/501100004835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004835","name":"Zhejiang University","doi-asserted-by":"publisher","award":["2023C03078"],"award-info":[{"award-number":["2023C03078"]}],"id":[{"id":"10.13039\/501100004835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004835","name":"Zhejiang University","doi-asserted-by":"publisher","award":["226\u20132022-00083"],"award-info":[{"award-number":["226\u20132022-00083"]}],"id":[{"id":"10.13039\/501100004835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004835","name":"Zhejiang University","doi-asserted-by":"publisher","award":["LR23H180002"],"award-info":[{"award-number":["LR23H180002"]}],"id":[{"id":"10.13039\/501100004835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy &amp; Behavior"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.yebeh.2023.109212","type":"journal-article","created":{"date-parts":[[2023,5,10]],"date-time":"2023-05-10T06:10:48Z","timestamp":1683699048000},"page":"109212","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Efficacy of different strategies of responsive neurostimulation on seizure control and their association with acute neurophysiological effects in rats"],"prefix":"10.1016","volume":"143","author":[{"given":"Fang","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjie","family":"Xin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junming","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kedi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.yebeh.2023.109212_b0005","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S1474-4422(18)30454-X","article-title":"Global, regional, and national burden of epilepsy, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"Beghi","year":"2019","journal-title":"Lancet Neurol"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109212_b0010","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.yebeh.2012.06.016","article-title":"Epilepsy across the spectrum: Promoting health and understanding","volume":"25","author":"England","year":"2012","journal-title":"Epilepsy Behav"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109212_b0015","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/WCO.0000000000000528","article-title":"The current place of epilepsy surgery","volume":"31","author":"Engel","year":"2018","journal-title":"Curr Opin Neurol"},{"issue":"12","key":"10.1016\/j.yebeh.2023.109212_b0020","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1111\/j.0013-9580.2004.26104.x","article-title":"Effect of an External Responsive Neurostimulator on Seizures and Electrographic Discharges during Subdural Electrode Monitoring","volume":"45","author":"Kossoff","year":"2004","journal-title":"Epilepsia"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0025","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/epi.12534","article-title":"Two-year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial","volume":"55","author":"Heck","year":"2014","journal-title":"Epilepsia"},{"issue":"8","key":"10.1016\/j.yebeh.2023.109212_b0030","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1212\/WNL.0000000000001280","article-title":"Long-term treatment with responsive brain stimulation in adults with refractory partial seizures","volume":"84","author":"Bergey","year":"2015","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109212_b0035","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1111\/epi.13740","article-title":"Brain-responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy","volume":"58","author":"Geller","year":"2017","journal-title":"Epilepsia"},{"issue":"8","key":"10.1016\/j.yebeh.2023.109212_b0040","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1111\/epi.16593","article-title":"Real-world experience with direct brain-responsive neurostimulation for focal onset seizures","volume":"61","author":"Razavi","year":"2020","journal-title":"Epilepsia"},{"issue":"9","key":"10.1016\/j.yebeh.2023.109212_b0045","doi-asserted-by":"crossref","first-page":"e1244","DOI":"10.1212\/WNL.0000000000010154","article-title":"Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy","volume":"95","author":"Nair","year":"2020","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2023.109212_b0050","doi-asserted-by":"crossref","DOI":"10.1152\/jn.2002.88.4.1592","article-title":"Extracellular stimulation of central neurons: influence of stimulus waveform and frequency on neuronal output","author":"McIntyre","year":"2002","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.yebeh.2023.109212_b0055","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/awac234","article-title":"Towards network-guided neuromodulation for epilepsy","author":"Piper","year":"2022","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0060","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1111\/epi.17163","article-title":"Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment","volume":"63","author":"Scheid","year":"2022","journal-title":"Epilepsia"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109212_b0065","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/abed82","article-title":"Quantifying a frequency modulation response biomarker in responsive neurostimulation","volume":"18","author":"Venkatesh","year":"2021","journal-title":"J Neural Eng"},{"key":"10.1016\/j.yebeh.2023.109212_b0070","doi-asserted-by":"crossref","unstructured":"Stieve BJ, Richner TJ, Krook-Magnuson C, Netoff TI, Krook-Magnuson E. Optimization of closed-loop electrical stimulation enables robust cerebellar-directed seizure control; 2021.","DOI":"10.1101\/2021.09.03.458908"},{"issue":"5","key":"10.1016\/j.yebeh.2023.109212_b0075","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/nrneurol.2014.59","article-title":"Electrical brain stimulation for epilepsy","volume":"10","author":"Fisher","year":"2014","journal-title":"Nat Rev Neurol"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0080","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/cns.13535","article-title":"Suppressing synchronous firing of epileptiform activity by high-frequency stimulation of afferent fibers in rat hippocampus","volume":"27","author":"Wang","year":"2021","journal-title":"CNS Neurosci Ther"},{"issue":"5","key":"10.1016\/j.yebeh.2023.109212_b0085","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.brs.2014.03.011","article-title":"High Frequency Stimulation Extends the Refractory Period and Generates Axonal Block in the Rat Hippocampus","volume":"7","author":"Feng","year":"2014","journal-title":"Brain Stimul"},{"key":"10.1016\/j.yebeh.2023.109212_b0090","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.brainresbull.2014.08.007","article-title":"Electrical stimulation of hippocampus for the treatment of refractory temporal lobe epilepsy","volume":"109","author":"Han","year":"2014","journal-title":"Brain Res Bull"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0095","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.nbd.2012.05.011","article-title":"Wide therapeutic time-window of low-frequency stimulation at the subiculum for temporal lobe epilepsy treatment in rats","volume":"48","author":"Zhong","year":"2012","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.yebeh.2023.109212_b0100","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.54518","article-title":"Hippocampal low-frequency stimulation prevents seizure generation in a mouse model of mesial temporal lobe epilepsy","volume":"9","author":"Paschen","year":"2020","journal-title":"Elife"},{"key":"10.1016\/j.yebeh.2023.109212_b0105","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3389\/fncir.2018.00022","article-title":"Low Frequency Microstimulation Is Locally Excitatory in Patients With Epilepsy","volume":"12","author":"Bartoli","year":"2018","journal-title":"Front Neural Circuits"},{"issue":"5","key":"10.1016\/j.yebeh.2023.109212_b0110","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/cns.13617","article-title":"Deep brain stimulation in the medial septum attenuates temporal lobe epilepsy via entrainment of hippocampal theta rhythm","volume":"27","author":"Wang","year":"2021","journal-title":"CNS Neurosci Ther"},{"issue":"2\u20133","key":"10.1016\/j.yebeh.2023.109212_b0115","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.eplepsyres.2009.11.014","article-title":"Comparison of hippocampal Deep Brain Stimulation with high (130Hz) and low frequency (5Hz) on afterdischarges in kindled rats","volume":"88","author":"Wyckhuys","year":"2010","journal-title":"Epilepsy Res"},{"issue":"1\u20132","key":"10.1016\/j.yebeh.2023.109212_b0120","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.eplepsyres.2013.03.009","article-title":"Thalamic stimulation in absence epilepsy","volume":"106","author":"Luttjohann","year":"2013","journal-title":"Epilepsy Res"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0125","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s002340000463","article-title":"The circuit of Papez in mesial temporal sclerosis: MRI","volume":"43","author":"Oikawa","year":"2001","journal-title":"Neuroradiology"},{"key":"10.1016\/j.yebeh.2023.109212_b0130","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.neuroscience.2013.10.059","article-title":"High-frequency stimulation of the hippocampus protects against seizure activity and hippocampal neuronal apoptosis induced by kainic acid administration in macaques","volume":"256","author":"Chen","year":"2014","journal-title":"Neuroscience"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109212_b0135","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/ner.12435","article-title":"Low and High Frequency Hippocampal Stimulation for Drug-Resistant Mesial Temporal Lobe Epilepsy","volume":"19","author":"Lim","year":"2016","journal-title":"Neuromodul: Technol Neural Interface"},{"key":"10.1016\/j.yebeh.2023.109212_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.pneurobio.2021.102029","article-title":"Dissecting the role of subiculum in epilepsy: Research update and translational potential","volume":"201","author":"Fei","year":"2021","journal-title":"Prog Neurobiol"},{"issue":"5","key":"10.1016\/j.yebeh.2023.109212_b0145","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/brb3.70","article-title":"The effects of acute responsive high frequency stimulation of the subiculum on the intra-hippocampal kainic acid seizure model in rats","volume":"2","author":"Huang","year":"2012","journal-title":"Brain Behavior"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0150","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.eplepsyres.2013.06.010","article-title":"The effects of responsive and scheduled subicular high frequency stimulation in the intra-hippocampal kainic acid seizure model","volume":"106","author":"Huang","year":"2013","journal-title":"Epilepsy Res"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0155","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.nbd.2009.09.022","article-title":"Network perspectives on the mechanisms of deep brain stimulation","volume":"38","author":"McIntyre","year":"2010","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.yebeh.2023.109212_b0160","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.yebeh.2013.12.034","article-title":"Focus on desynchronization rather than excitability: a new strategy for intraencephalic electrical stimulation","volume":"38","author":"de Castro","year":"2014","journal-title":"Epilepsy Behav"},{"issue":"4","key":"10.1016\/j.yebeh.2023.109212_b0165","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/ab9909","article-title":"Optimizing neuromodulation based on surrogate neural states for seizure suppression in a rat temporal lobe epilepsy model","volume":"17","author":"Park","year":"2020","journal-title":"J Neural Eng"},{"key":"10.1016\/j.yebeh.2023.109212_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.116967","article-title":"Desynchronization of temporal lobe theta-band activity during effective anterior thalamus deep brain stimulation in epilepsy","volume":"218","author":"Scherer","year":"2020","journal-title":"Neuroimage"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109212_b0175","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jneumeth.2008.04.019","article-title":"The pilocarpine model of temporal lobe epilepsy","volume":"172","author":"Curia","year":"2008","journal-title":"J Neurosci Methods"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0180","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/0306-4522(87)90171-0","article-title":"The functional anatomy and pathology of lithium-pilocarpine and high-dose pilocarpine seizures","volume":"23","author":"Clifford","year":"1987","journal-title":"Neuroscience"},{"issue":"5","key":"10.1016\/j.yebeh.2023.109212_b0185","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.physbeh.2009.09.005","article-title":"A revised Racine's scale for PTZ-induced seizures in rats","volume":"98","author":"Luttjohann","year":"2009","journal-title":"Physiol Behav"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109212_b0190","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0920-1211(01)00272-8","article-title":"Repeated low-dose treatment of rats with pilocarpine: low mortality but high proportion of rats developing epilepsy","volume":"46","author":"Glien","year":"2001","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2023.109212_b0195","series-title":"Experimental models of status epilepticus. Neuropharmacology methods in epilepsy research","first-page":"95","author":"Goodman","year":"2019"},{"key":"10.1016\/j.yebeh.2023.109212_b0200","doi-asserted-by":"crossref","unstructured":"B\u00fcttner-Ennever JJTJoA. The rat brain in stereotaxic coordinates, 3rd edn. By George Paxinos and Charles Watson (pp. xxxiii+ 80; illustrated;\u00a3 $69.95 paperback; ISBN 0 12 547623; comes with CD-ROM.) San Diego: Academic Press. 1996. 1997;191(2):315\u20137.","DOI":"10.1017\/S0021878297232310"},{"key":"10.1016\/j.yebeh.2023.109212_b0205","doi-asserted-by":"crossref","unstructured":"Zheng Y, Gao H, Zhang J, Wang Y, Zhang S, Xu K, editors. Multi-site closed-loop stimulation strategy for seizure control with a generalized neurostimulator2017: IEEE.","DOI":"10.1109\/NER.2017.8008340"},{"issue":"11","key":"10.1016\/j.yebeh.2023.109212_b0210","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.1109\/TNSRE.2019.2947426","article-title":"An Energy Efficient AdaBoost Cascade Method for Long-Term Seizure Detection in Portable Neurostimulators","volume":"27","author":"Xu","year":"2019","journal-title":"IEEE Trans Neural Syst Rehabil Eng"},{"issue":"3","key":"10.1016\/j.yebeh.2023.109212_b0215","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1109\/TBME.2012.2189113","article-title":"Synchrony Dynamics Across Brain Structures in Limbic Epilepsy Vary Between Initiation and Termination Phases of Seizures","volume":"60","author":"Sobayo","year":"2013","journal-title":"IEEE Trans Biomed Eng"},{"key":"10.1016\/j.yebeh.2023.109212_b0220","doi-asserted-by":"crossref","unstructured":"Granger CWJEjotES. Investigating causal relations by econometric models and cross-spectral methods. 1969:424\u201338.","DOI":"10.2307\/1912791"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0225","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jneumeth.2010.03.007","article-title":"Granger causality relationships between local field potentials in an animal model of temporal lobe epilepsy","volume":"189","author":"Cadotte","year":"2010","journal-title":"J Neurosci Methods"},{"issue":"8","key":"10.1016\/j.yebeh.2023.109212_b0230","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1523\/JNEUROSCI.4399-14.2015","article-title":"Granger Causality Analysis in Neuroscience and Neuroimaging","volume":"35","author":"Seth","year":"2015","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0235","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1093\/neuros\/nyx195","article-title":"Granger Causality Analysis of Interictal iEEG Predicts Seizure Focus and Ultimate Resection","volume":"82","author":"Park","year":"2018","journal-title":"Neurosurgery"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0240","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s00422-009-0350-5","article-title":"Evaluating the effective connectivity of resting state networks using conditional Granger causality","volume":"102","author":"Liao","year":"2010","journal-title":"Biol Cybern"},{"issue":"1A","key":"10.1016\/j.yebeh.2023.109212_b0245","first-page":"153","article-title":"Towards optimal model order selection for autoregressive spectral analysis of mental tasks using genetic algorithm","volume":"6","author":"Palaniappan","year":"2006","journal-title":"Int J Comput Sci Network Security"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109212_b0250","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s00422-015-0665-3","article-title":"Conditional Granger causality and partitioned Granger causality: differences and similarities","volume":"109","author":"Malekpour","year":"2015","journal-title":"Biol Cybern"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109212_b0255","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1109\/TAC.1974.1100705","article-title":"A new look at the statistical model identification","volume":"19","author":"Akaike","year":"1974","journal-title":"IEEE Trans Autom Control"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0260","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0165-0270(02)00366-7","article-title":"The use of time-variant EEG Granger causality for inspecting directed interdependencies of neural assemblies","volume":"124","author":"Hesse","year":"2003","journal-title":"J Neurosci Methods"},{"issue":"2","key":"10.1016\/j.yebeh.2023.109212_b0265","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jneumeth.2009.11.020","article-title":"A MATLAB toolbox for Granger causal connectivity analysis","volume":"186","author":"Seth","year":"2010","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.yebeh.2023.109212_b0270","doi-asserted-by":"crossref","unstructured":"Buzs\u00e1ki G. Rhythms of the Brain: Oxford University Press; 2006 01 May 2009.","DOI":"10.1093\/acprof:oso\/9780195301069.001.0001"},{"issue":"5","key":"10.1016\/j.yebeh.2023.109212_b0275","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1109\/TBME.2014.2311996","article-title":"A Review of Multitaper Spectral Analysis","volume":"61","author":"Babadi","year":"2014","journal-title":"IEEE Trans Biomed Eng"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0280","first-page":"60","article-title":"Sleep Neurophysiological Dynamics Through the Lens of Multitaper Spectral Analysis","volume":"32","author":"Prerau","year":"2017","journal-title":"Physiology (Bethesda)"},{"issue":"Pt 1","key":"10.1016\/j.yebeh.2023.109212_b0285","first-page":"65","article-title":"Assessing seizure dynamics by analysing the correlation structure of multichannel intracranial EEG","volume":"130","author":"Schindler","year":"2007","journal-title":"Brain"},{"issue":"11","key":"10.1016\/j.yebeh.2023.109212_b0290","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1080\/17434440.2021.1994388","article-title":"Chronic electroencephalography in epilepsy with a responsive neurostimulation device: current status and future prospects","volume":"18","author":"Rao","year":"2021","journal-title":"Expert Rev Med Devices"},{"issue":"Supplement 9","key":"10.1016\/j.yebeh.2023.109212_b0295","first-page":"326","article-title":"Multicenter study of acute responsive stimulation in patients with intractable epilepsy","volume":"44","author":"Murro","year":"2003","journal-title":"Epilepsia"},{"issue":"31","key":"10.1016\/j.yebeh.2023.109212_b0300","doi-asserted-by":"crossref","first-page":"6122","DOI":"10.1523\/JNEUROSCI.0535-19.2019","article-title":"Intracortical Dynamics Underlying Repetitive Stimulation Predicts Changes in Network Connectivity","volume":"39","author":"Huang","year":"2019","journal-title":"J Neurosci"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0305","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2552\/abd048","article-title":"A framework for designing data-driven optimization systems for neural modulation","volume":"18","author":"Connolly","year":"2021","journal-title":"J Neural Eng"},{"issue":"1","key":"10.1016\/j.yebeh.2023.109212_b0310","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1177\/15357597211065587","article-title":"Neuromodulation for Refractory Epilepsy","volume":"22","author":"Ryvlin","year":"2022","journal-title":"Epilepsy Curr"},{"issue":"47","key":"10.1016\/j.yebeh.2023.109212_b0315","doi-asserted-by":"crossref","first-page":"15635","DOI":"10.1523\/JNEUROSCI.5112-14.2015","article-title":"Brain State Is a Major Factor in Preseizure Hippocampal Network Activity and Influences Success of Seizure Intervention","volume":"35","author":"Ewell","year":"2015","journal-title":"J Neurosci"},{"issue":"10","key":"10.1016\/j.yebeh.2023.109212_b0320","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1111\/j.1528-1167.2008.01669.x","article-title":"How do seizures stop?","volume":"49","author":"Lado","year":"2008","journal-title":"Epilepsia"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109212_b0325","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1111\/epi.16895","article-title":"The SANT\u00c9 study at 10 years of follow-up: Effectiveness, safety, and sudden unexpected death in epilepsy","volume":"62","author":"Salanova","year":"2021","journal-title":"Epilepsia"},{"issue":"7","key":"10.1016\/j.yebeh.2023.109212_b0330","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1001\/jamaneurol.2019.0658","article-title":"Association of Closed-Loop Brain Stimulation Neurophysiological Features With Seizure Control Among Patients With Focal Epilepsy","volume":"76","author":"Kokkinos","year":"2019","journal-title":"JAMA Neurol"},{"issue":"108","key":"10.1016\/j.yebeh.2023.109212_b0335","doi-asserted-by":"crossref","first-page":"eabf6588","DOI":"10.1126\/scitranslmed.abf6588","article-title":"Long-term brain network reorganization predicts responsive neurostimulation outcomes for focal epilepsy","volume":"13","author":"Khambhati","year":"2021","journal-title":"Sci Transl Med"},{"issue":"6","key":"10.1016\/j.yebeh.2023.109212_b0340","doi-asserted-by":"crossref","first-page":"3645","DOI":"10.1152\/jn.00040.2006","article-title":"Septo-Hippocampal Networks in Chronically Epileptic Rats: Potential Antiepileptic Effects of Theta Rhythm Generation","volume":"95","author":"Colom","year":"2006","journal-title":"J Neurophysiol"}],"container-title":["Epilepsy &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505023001312?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505023001312?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T18:49:51Z","timestamp":1761504591000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505023001312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":68,"alternative-id":["S1525505023001312"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2023.109212","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of different strategies of responsive neurostimulation on seizure control and their association with acute neurophysiological effects in rats","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2023.109212","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"109212"}}