{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:26:04Z","timestamp":1786998364149,"version":"build-2736575974"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.yebeh.2024.109838","type":"journal-article","created":{"date-parts":[[2024,5,19]],"date-time":"2024-05-19T06:46:02Z","timestamp":1716101162000},"page":"109838","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["The relationship of psychiatric comorbidities and symptoms, quality of life, and stigmatization in patients with epilepsy"],"prefix":"10.1016","volume":"156","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0885-5562","authenticated-orcid":false,"given":"Tural","family":"Tal\u0131bov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0365-892X","authenticated-orcid":false,"given":"Meltem","family":"\u0130nci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5931-9508","authenticated-orcid":false,"given":"Rashad","family":"Ismay\u0131lov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0049-5352","authenticated-orcid":false,"given":"Sibel","family":"Elmas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8648-3812","authenticated-orcid":false,"given":"Emiralp","family":"B\u00fcy\u00fcktop\u00e7u","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ata Onur","family":"Kepenek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6rkem","family":"\u015eirin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3631-6018","authenticated-orcid":false,"given":"Irmak","family":"Polat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2981-9541","authenticated-orcid":false,"given":"Mine","family":"\u00d6zkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4749-1471","authenticated-orcid":false,"given":"Nerses","family":"Bebek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2024.109838_b0005","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1111\/j.1528-1167.2007.01222.x","article-title":"Psychiatric comorbidity in epilepsy: A population-based analysis","volume":"48","author":"Tellez-Zenteno","year":"2007","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0010","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.yebeh.2005.04.012","article-title":"Psychiatric comorbidity in epilepsy","volume":"7","author":"Swinkels","year":"2005","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2024.109838_b0015","first-page":"94","article-title":"Study of psychiatric comorbidities in epilepsy by using the Mini International Neuropsychiatric Interview","volume":"33","author":"Amruth","year":"2014","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0020","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1528-1157.2000.tb01522.x","article-title":"Psychiatric comorbidity in chronic epilepsy: identification, consequences, and treatment of major depression","volume":"41","author":"Hermann","year":"2000","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0025","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1212\/01.WNL.0000138430.11829.61","article-title":"Depression and comorbidity in community-based patients with epilepsy or asthma","volume":"63","author":"Ettinger","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2024.109838_b0030","first-page":"74","article-title":"Juvenile myoclonic epilepsy: Psychiatric comorbidity and impact on outcome","volume":"28","author":"De Araujo Filho","year":"2013","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0035","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1002\/ana.23601","article-title":"Epilepsy, suicidality, and psychiatric disorders: a bidirectional association","volume":"72","author":"Hesdorffer","year":"2012","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2024.109838_b0040","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1212\/WNL.0b013e318245f461","article-title":"Hospitalization for psychiatric disorders before and after onset of unprovoked seizures\/epilepsy","volume":"78","author":"Adel\u00f6w","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2024.109838_b0045","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1111\/epi.17012","article-title":"Quality of Life in Epilepsy: Same questions, but different meaning to different people","volume":"62","author":"Sajobi","year":"2021","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0050","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.seizure.2009.03.001","article-title":"Identifying depression in epilepsy in a busy clinical setting is enhanced with systematic screening","volume":"18","author":"Friedman","year":"2009","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2024.109838_b0055","first-page":"593","article-title":"Psychiatric comorbidity in refractory focal epilepsy: A study of 490 patients","volume":"25","author":"Dalmagro","year":"2012","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0060","first-page":"1","article-title":"Factors contributing to the development of perceived stigma in people with newly diagnosed epilepsy: A one-year longitudinal study","volume":"54","author":"Lee","year":"2016","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0065","article-title":"SCL-90-R: Administration, scoring & procedures manual-II for the R(evised) version","author":"Derogatis","year":"1977","journal-title":"Clin Psychometric Res"},{"key":"10.1016\/j.yebeh.2024.109838_b0070","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1111\/j.1528-1157.1996.tb00612.x","article-title":"A brief questionnaire to screen for quality of life in epilepsy the QOLIE-10","volume":"37","author":"Cramer","year":"1996","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0075","doi-asserted-by":"crossref","first-page":"239","DOI":"10.5152\/npa.2016.13809","article-title":"Validity and reliability of the quality of life in epilepsy inventory (QOLIE-10) for Turkey","volume":"54","author":"Mollao\u011flu","year":"2017","journal-title":"Noropsikiyatri Arsivi"},{"key":"10.1016\/j.yebeh.2024.109838_b0080","article-title":"Epilepsy and the quality of everyday life findings from a study of people with well-controlled epilepsy","volume":"34","author":"Jacoby","year":"1992","journal-title":"Soc Sci Med"},{"key":"10.1016\/j.yebeh.2024.109838_b0085","doi-asserted-by":"crossref","unstructured":"Sheehan David V., Lecrubier Yves, Sheehan Harnett, Amorim Patricia, Janavs Juris, Weiller Emmanuelle, et al. The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 1998;59:22\u201333.","DOI":"10.1037\/t18597-000"},{"key":"10.1016\/j.yebeh.2024.109838_b0090","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s00228-010-0861-y","article-title":"Psychiatric comorbidity in patients with epilepsy: a population-based study","volume":"66","author":"Karouni","year":"2010","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.yebeh.2024.109838_b0095","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1111\/j.1528-1167.2007.01222.x","article-title":"Psychiatric comorbidity in epilepsy: A population-based","volume":"48","author":"Williams","year":"2007","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0100","doi-asserted-by":"crossref","first-page":"176","DOI":"10.3988\/jcn.2021.17.2.176","article-title":"Systematic literature review of psychiatric comorbidities in adults with epilepsy","volume":"17","author":"Lu","year":"2021","journal-title":"J Clin Neurol"},{"key":"10.1016\/j.yebeh.2024.109838_b0105","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1212\/WNL.0b013e31827b1ae0","article-title":"Depression in epilepsy: A systematic review and meta-analysis","volume":"80","author":"Fiest","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2024.109838_b0110","first-page":"51","article-title":"Frequency of affective symptoms and their psychosocial impact in Korean people with epilepsy: A survey at two tertiary care hospitals","volume":"26","author":"Kwon","year":"2013","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0115","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.yebeh.2018.06.046","article-title":"Interictal psychiatric comorbidities of drug-resistant focal epilepsy: Prevalence and in fl uence of the localization of the epilepsy","volume":"94","author":"Jansen","year":"2019","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2024.109838_b0120","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s11910-002-0012-7","article-title":"Neuropsychiatric complications of epilepsy","volume":"2","author":"Kanner","year":"2002","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"39\u201345","key":"10.1016\/j.yebeh.2024.109838_b0125","article-title":"Mood disorder and epilepsy: a neurobiologic perspective of their relationship","volume":"10","author":"Kanner","year":"2008","journal-title":"Dialogues Clin Neurosci"},{"key":"10.1016\/j.yebeh.2024.109838_b0130","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.eplepsyres.2014.10.003","article-title":"Chronic stress shifts the GABA reversal potential in the hippocampus and increases seizure susceptibility","volume":"109","author":"MacKenzie","year":"2015","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2024.109838_b0135","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1111\/j.1528-1167.2007.01217.x","article-title":"A controlled prospective investigation of psychiatric comorbidity in temporal lobe epilepsy","volume":"48","author":"Jones","year":"2007","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0140","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1007\/s11910-014-0444-x","article-title":"Stigma in epilepsy","volume":"14","author":"Fiest","year":"2014","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.yebeh.2024.109838_b0145","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/WCO.0000000000000431","article-title":"Depression in epilepsy","volume":"30","author":"Mula","year":"2017","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.yebeh.2024.109838_b0150","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1111\/j.0013-9580.2004.47003.x","article-title":"The relative impact of anxiety, depression, and clinical seizure features on health-related quality of life in epilepsy","volume":"45","author":"Johnson","year":"2004","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0155","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.eplepsyres.2008.09.001","article-title":"Factors associated with impaired quality of life in younger and older adults with epilepsy","volume":"83","author":"Canuet","year":"2009","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2024.109838_b0160","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.yebeh.2014.05.011","article-title":"The relationship of depression to antiepileptic drug adherence and quality of life in epilepsy","volume":"36","author":"Ettinger","year":"2014","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2024.109838_b0165","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1111\/epi.12625","article-title":"Epilepsy surgery and meaningful improvements in quality of life: Results from a randomized controlled trial","volume":"55","author":"Fiest","year":"2014","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.109838_b0170","first-page":"18","article-title":"Evaluating quality of life in epilepsy: The role of screening for adverse drug effects, depression, and anxiety","volume":"75","author":"Micoulaud-Franchi","year":"2017","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0175","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S1059-1311(03)00111-0","article-title":"Psychiatric adverse events in patients with epilepsy and learning disabilities taking levetiracetam","volume":"13","author":"Mula","year":"2004","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2024.109838_b0180","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.eplepsyres.2007.08.005","article-title":"Changes in depression, anxiety, anger, and personality after resective surgery for drug-resistant temporal lobe epilepsy: a 2-year follow-up study","volume":"77","author":"Meldolesi","year":"2007","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2024.109838_b0185","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.seizure.2006.12.004","article-title":"Psychiatric disorders in temporal lobe patients with epilepsy over the first year after surgical treatment","volume":"16","author":"Pintor","year":"2007","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2024.109838_b0190","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1212\/01.wnl.0000187114.71524.c3","article-title":"Changes in depression and anxiety after resective surgery for epilepsy","volume":"65","author":"Devinsky","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2024.109838_b0195","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S1059-1311(03)00073-6","article-title":"Depression and anxiety before and after temporal lobe epilepsy surgery","volume":"13","author":"Reuber","year":"2004","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2024.109838_b0200","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1176\/jnp.11.4.436","article-title":"Temporal lobe epilepsy, temporal lobectomy, and major depression","volume":"11","author":"Altshuler","year":"1999","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"10.1016\/j.yebeh.2024.109838_b0205","first-page":"272","article-title":"Psychiatric comorbidity in patients with pharmacoresistant focal epilepsy and psychiatric outcome after epilepsy surgery","volume":"23","author":"Hellwig","year":"2012","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0225","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1177\/0883073815587942","article-title":"Anxiety and depression in adolescents with epilepsy","volume":"31","author":"Kwong","year":"2016","journal-title":"J Child Neurol"},{"key":"10.1016\/j.yebeh.2024.109838_b0230","first-page":"365","article-title":"Try out PMC Labs and tell us what you think. Learn More. Epilepsy in general practice: patients\u2019 psychological symptoms and their perception of stigma","volume":"46","author":"R\u0131dsdale","year":"1996","journal-title":"British J General Pract"},{"key":"10.1016\/j.yebeh.2024.109838_b0235","first-page":"37","article-title":"Psychiatric disorders among 165 patients with juvenile myoclonic epilepsy in India and association with clinical and sociodemographic variables","volume":"53","author":"Somayajula","year":"2015","journal-title":"EpilepsyBehav"},{"key":"10.1016\/j.yebeh.2024.109838_b0240","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.yebeh.2009.02.014","article-title":"Sociodemographic and clinical factors associated with depression in epilepsy","volume":"14","author":"Thompson","year":"2009","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2024.109838_b0245","first-page":"154","article-title":"Psychiatric symptoms after temporal epilepsy surgery. A one-year follow-up study","volume":"70","author":"Iranzo-Tatay","year":"2017","journal-title":"EpilepsyBehav"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505024002191?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505024002191?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T20:23:42Z","timestamp":1738441422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505024002191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":46,"alternative-id":["S1525505024002191"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2024.109838","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The relationship of psychiatric comorbidities and symptoms, quality of life, and stigmatization in patients with epilepsy","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2024.109838","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"109838"}}