{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:12:55Z","timestamp":1792188775468,"version":"4.4.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,7]],"date-time":"2024-12-07T00:00:00Z","timestamp":1733529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004350","name":"Studienstiftung des Deutschen Volkes","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004350","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007443","name":"Friedrich Naumann Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007443","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy &amp; Behavior"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.yebeh.2024.110214","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T22:00:14Z","timestamp":1734040814000},"page":"110214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Animal welfare assessment after controlled cortical impact in CD-1 mice \u2013 A model of posttraumatic epilepsy"],"prefix":"10.1016","volume":"163","author":[{"given":"Ricardo","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Welzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"L\u00f6scher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2024.110214_b0005","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1177\/00236772221107269","article-title":"Animal welfare assessment after severe traumatic brain injury in rats","volume":"56","author":"Allioux","year":"2022","journal-title":"Lab Anim"},{"key":"10.1016\/j.yebeh.2024.110214_b0010","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.yebeh.2018.09.016","article-title":"Automated quantification of EEG spikes and spike clusters as a new read out in Theiler's virus mouse model of encephalitis-induced epilepsy","volume":"88","author":"Anjum","year":"2018","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2024.110214_b0015","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1089\/neu.1997.14.839","article-title":"Time course of cerebral edema after traumatic brain injury in rats: effects of riluzole and mannitol","volume":"14","author":"Bareyre","year":"1997","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.yebeh.2024.110214_b0020","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1089\/neu.2006.0011","article-title":"Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injury","volume":"24","author":"Brody","year":"2007","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.yebeh.2024.110214_b0025","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.expneurol.2016.02.011","article-title":"Brain inflammation, neurodegeneration and seizure development following picornavirus infection markedly differ among virus and mouse strains and substrains","volume":"279","author":"Br\u00f6er","year":"2016","journal-title":"Exp Neurol"},{"key":"10.1016\/j.yebeh.2024.110214_b0030","doi-asserted-by":"crossref","first-page":"163","DOI":"10.3389\/fnsys.2015.00163","article-title":"Effects of Rapamycin Treatment on Neurogenesis and Synaptic Reorganization in the Dentate Gyrus after Controlled Cortical Impact Injury in Mice","volume":"9","author":"Butler","year":"2015","journal-title":"Front Syst Neurosci"},{"key":"10.1016\/j.yebeh.2024.110214_b0035","series-title":"Assessing burrowing, nest construction, and hoarding in mice","first-page":"e2607","author":"Deacon","year":"2012"},{"key":"10.1016\/j.yebeh.2024.110214_b0040","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s40478-021-01165-y","article-title":"In-depth characterization of a mouse model of post-traumatic epilepsy for biomarker and drug discovery","volume":"9","author":"Di Sapia","year":"2021","journal-title":"Acta Neuropathol Commun"},{"key":"10.1016\/j.yebeh.2024.110214_b0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2023.106251","article-title":"ECoG spiking activity and signal dimension are early predictive measures of epileptogenesis in a translational mouse model of traumatic brain injury","volume":"185","author":"Di Sapia","year":"2023","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.yebeh.2024.110214_b0050","doi-asserted-by":"crossref","first-page":"1371213","DOI":"10.3389\/fncel.2024.1371213","article-title":"An overview of preclinical models of traumatic brain injury (TBI): relevance to pathophysiological mechanisms","volume":"18","author":"Fesharaki-Zadeh","year":"2024","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.yebeh.2024.110214_b0055","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1007\/s00415-020-09926-w","article-title":"A review of seizures and epilepsy following traumatic brain injury","volume":"267","author":"Fordington","year":"2020","journal-title":"J Neurol"},{"key":"10.1016\/j.yebeh.2024.110214_b0060","series-title":"Nest building as an indicator of health and welfare in laboratory mice","first-page":"e51012","author":"Gaskill","year":"2013"},{"key":"10.1016\/j.yebeh.2024.110214_b0065","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1124\/pharmrev.121.000375","article-title":"Post-Traumatic Epilepsy and Comorbidities: Advanced Models, Molecular Mechanisms, Biomarkers, and Novel Therapeutic Interventions","volume":"74","author":"Golub","year":"2022","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.yebeh.2024.110214_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2021.113946","article-title":"Contusion brain damage in mice for modelling of post-traumatic epilepsy with contralateral hippocampus sclerosis: Comprehensive and longitudinal characterization of spontaneous seizures, neuropathology, and neuropsychiatric comorbidities","volume":"348","author":"Golub","year":"2022","journal-title":"Exp Neurol"},{"key":"10.1016\/j.yebeh.2024.110214_b0075","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.bpa.2020.06.003","article-title":"A comprehensive review of partial opioid agonists for the treatment of chronic pain","volume":"34","author":"Gress","year":"2020","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"10.1016\/j.yebeh.2024.110214_b0080","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.3390\/cells12091248","article-title":"Atypical Neurogenesis, Astrogliosis, and Excessive Hilar Interneuron Loss Are Associated with the Development of Post-Traumatic Epilepsy","volume":"12","author":"Gudenschwager-Basso","year":"2023","journal-title":"Cells"},{"key":"10.1016\/j.yebeh.2024.110214_b0085","doi-asserted-by":"crossref","first-page":"e64078","DOI":"10.1371\/journal.pone.0064078","article-title":"Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury","volume":"8","author":"Guo","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.yebeh.2024.110214_b0090","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jpain.2020.04.004","article-title":"Methadone in Pain Management: A Systematic Review","volume":"22","author":"Hanna","year":"2021","journal-title":"J Pain"},{"key":"10.1016\/j.yebeh.2024.110214_b0095","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.expneurol.2008.10.005","article-title":"Posttraumatic epilepsy after controlled cortical impact injury in mice","volume":"215","author":"Hunt","year":"2009","journal-title":"Exp Neurol"},{"key":"10.1016\/j.yebeh.2024.110214_b0100","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1152\/jn.00957.2009","article-title":"Regionally localized recurrent excitation in the dentate gyrus of a cortical contusion model of posttraumatic epilepsy","volume":"103","author":"Hunt","year":"2010","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.yebeh.2024.110214_b0105","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/0023677213475603","article-title":"Assessment of postsurgical distress and pain in laboratory mice by nest complexity scoring","volume":"47","author":"Jirkof","year":"2013","journal-title":"Lab Anim"},{"key":"10.1016\/j.yebeh.2024.110214_b0110","doi-asserted-by":"crossref","unstructured":"Keith,K.A. and Huang,J.H. (2019). Animal Models of Post-Traumatic Epilepsy. Diagnostics. (Basel) 10, 4.","DOI":"10.3390\/diagnostics10010004"},{"key":"10.1016\/j.yebeh.2024.110214_b0115","doi-asserted-by":"crossref","first-page":"1143109","DOI":"10.3389\/fnins.2023.1143109","article-title":"Anesthesia and analgesia for experimental craniotomy in mice and rats: a systematic scoping review comparing the years 2009 and 2019","volume":"17","author":"King","year":"2023","journal-title":"Front Neurosci"},{"key":"10.1016\/j.yebeh.2024.110214_b0120","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/s41573-024-00981-w","article-title":"New epilepsy therapies in development","volume":"23","author":"Klein","year":"2024","journal-title":"Nat Rev Drug Discov"},{"key":"10.1016\/j.yebeh.2024.110214_b0125","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1002\/epi4.12462","article-title":"Sleep-wake characteristics in a mouse model of severe traumatic brain injury: Relation to posttraumatic epilepsy","volume":"6","author":"Konduru","year":"2021","journal-title":"Epilepsia Open"},{"key":"10.1016\/j.yebeh.2024.110214_b0130","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2021.763428","article-title":"Combining Animal Welfare With Experimental Rigor to Improve Reproducibility in Behavioral Neuroscience","volume":"15","author":"Loss","year":"2021","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.yebeh.2024.110214_b0135","doi-asserted-by":"crossref","first-page":"e10656","DOI":"10.1590\/1414-431x202010656","article-title":"Modeling of post-traumatic epilepsy and experimental research aimed at its prevention","volume":"54","author":"Mosini","year":"2020","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.yebeh.2024.110214_b0140","doi-asserted-by":"crossref","first-page":"18691","DOI":"10.1038\/s41598-024-69075-2","article-title":"Refining pain management in mice by comparing multimodal analgesia and NSAID monotherapy for neurosurgical procedures","volume":"14","author":"Munk","year":"2024","journal-title":"Sci Rep"},{"key":"10.1016\/j.yebeh.2024.110214_b0145","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3389\/fneur.2016.00134","article-title":"The Controlled Cortical Impact Model: Applications, Considerations for Researchers, and Future Directions","volume":"7","author":"Osier","year":"2016","journal-title":"Front Neurol"},{"key":"10.1016\/j.yebeh.2024.110214_b0150","unstructured":"Paxinos,G. and Franklin,K.B. (2019). Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates. Fifth Edition. (Norwich, N.Y.: William Andrew Publishing)."},{"key":"10.1016\/j.yebeh.2024.110214_b0155","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/s41582-024-00954-y","article-title":"Insights into epileptogenesis from post-traumatic epilepsy","volume":"20","author":"Pease","year":"2024","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.yebeh.2024.110214_b0160","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1177\/0023677216675010","article-title":"Severity assessment and scoring for neurosurgical models in rodents","volume":"50","author":"Pinkernell","year":"2016","journal-title":"Lab Anim"},{"key":"10.1016\/j.yebeh.2024.110214_b0165","doi-asserted-by":"crossref","unstructured":"Pitk\u00e4nen,A., Kyyri\u00e4inen,J., Andrade,P., Pasanen,L., and Ndode-Ekane,X.E. (2017). Epilepsy after traumatic brain injury. In Models of seizures and epilepsy. Second Edition., A.Pitk\u00e4nen, P.S.Buckmaster, A.S.Galanopoulou, and S.L.Mosh\u00e9, eds. (London, U.K.: Academic Press), pp. 661-682.","DOI":"10.1016\/B978-0-12-804066-9.00046-8"},{"key":"10.1016\/j.yebeh.2024.110214_b0170","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.neuropharm.2011.05.010","article-title":"Low dose methamphetamine mediates neuroprotection through a PI3K-AKT pathway","volume":"61","author":"Rau","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.yebeh.2024.110214_b0175","doi-asserted-by":"crossref","first-page":"S165","DOI":"10.1097\/TA.0b013e318260896a","article-title":"Treatment with low-dose methamphetamine improves behavioral and cognitive function after severe traumatic brain injury","volume":"73","author":"Rau","year":"2012","journal-title":"J Trauma Acute Care Surg"},{"key":"10.1016\/j.yebeh.2024.110214_b0180","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.expneurol.2013.12.001","article-title":"Administration of low dose methamphetamine 12 h after a severe traumatic brain injury prevents neurological dysfunction and cognitive impairment in rats","volume":"253","author":"Rau","year":"2014","journal-title":"Exp Neurol"},{"key":"10.1016\/j.yebeh.2024.110214_b0185","doi-asserted-by":"crossref","first-page":"6005","DOI":"10.1172\/JCI134793","article-title":"Preventing neuronal edema increases network excitability after traumatic brain injury","volume":"130","author":"Sawant-Pokam","year":"2020","journal-title":"J Clin Invest"},{"key":"10.1016\/j.yebeh.2024.110214_b0190","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.eplepsyres.2018.09.005","article-title":"Convulsive seizures and EEG spikes after lateral fluid-percussion injury in the rat","volume":"147","author":"Smith","year":"2018","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2024.110214_b0195","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.neuroscience.2019.12.006","article-title":"Aquaporin-4 dysregulation in a controlled cortical impact injury model of posttraumatic epilepsy","volume":"428","author":"Szu","year":"2020","journal-title":"Neuroscience"},{"key":"10.1016\/j.yebeh.2024.110214_bib196","doi-asserted-by":"crossref","first-page":"1151660","DOI":"10.3389\/fneur.2023.1151660","article-title":"Models of traumatic brain injury - highlights and drawbacks","volume":"14","author":"Zhao","year":"2023","journal-title":"Front Neurol"}],"container-title":["Epilepsy &amp; Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505024005961?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505024005961?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T15:02:07Z","timestamp":1739458927000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505024005961"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":40,"alternative-id":["S1525505024005961"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2024.110214","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Animal welfare assessment after controlled cortical impact in CD-1 mice \u2013 A model of posttraumatic epilepsy","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2024.110214","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"110214"}}