{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:26:32Z","timestamp":1786998392711,"version":"build-2736575974"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T00:00:00Z","timestamp":1737676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.yebeh.2024.110221","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T08:26:33Z","timestamp":1733991993000},"page":"110221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Maternal epilepsy and pregnancy, delivery and neonatal outcomes: A population-based retrospective cohort study"],"prefix":"10.1016","volume":"163","author":[{"given":"Noah","family":"Margolese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Badeghiesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitham","family":"Baghlaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Jacobson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H","family":"Dahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2024.110221_b0005","first-page":"11","author":"Giourou","year":"2015","journal-title":"Introduction to Epilepsy and Related Brain Disorders"},{"key":"10.1016\/j.yebeh.2024.110221_b0010","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1684\/epd.2019.1105","article-title":"Management of epilepsy in pregnancy: a report from the international league against epilepsy task force on women and pregnancy","volume":"21","author":"Tomson","year":"2019","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.yebeh.2024.110221_b0015","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1007\/s11064-017-2262-4","article-title":"Neurodevelopmental effects of antiepileptic drugs","volume":"42","author":"Kellogg","year":"2017","journal-title":"Neurochem Res"},{"key":"10.1016\/j.yebeh.2024.110221_b0020","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1212\/CON.0000000000001056","article-title":"Epilepsy and pregnancy","volume":"28","author":"Li","year":"2022","journal-title":"CONTINUUM Lifelong Learning in Neurology"},{"key":"10.1016\/j.yebeh.2024.110221_b0025","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4103\/2277-9175.94426","article-title":"The course and outcome of pregnancy and neonatal situation in epileptic women","volume":"1","author":"Najafi","year":"2012","journal-title":"Adv Biomed Res"},{"key":"10.1016\/j.yebeh.2024.110221_b0030","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1001\/archneurol.2009.142","article-title":"Affect of seizures during gestation on pregnancy outcomes in women with epilepsy","volume":"66","author":"Chen","year":"2009","journal-title":"Arch Neurol"},{"key":"10.1016\/j.yebeh.2024.110221_b0035","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1111\/j.1471-0528.2011.03004.x","article-title":"Obstetric outcome in women with epilepsy: a hospital-based, retrospective study","volume":"118","author":"Borthen","year":"2011","journal-title":"BJOG"},{"key":"10.1016\/j.yebeh.2024.110221_b0040","doi-asserted-by":"crossref","first-page":"e2356425","DOI":"10.1001\/jamanetworkopen.2023.56425","article-title":"Prenatal exposure to antiseizure medications and risk of epilepsy in children of mothers with epilepsy","volume":"7","author":"Dreier","year":"2024","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.yebeh.2024.110221_b0045","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1001\/jamaneurol.2023.0148","article-title":"Comparison of perinatal outcomes for women with and without epilepsy: a systematic review and meta-analysis","volume":"80","author":"Mazzone","year":"2023","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.yebeh.2024.110221_b0050","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/j.ijsu.2014.07.013","article-title":"The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"12","author":"von Elm","year":"2014","journal-title":"Int J Surg"},{"key":"10.1016\/j.yebeh.2024.110221_b0055","unstructured":"Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans \u2013 TCPS 2 (2022) n.d. https:\/\/ethics.gc.ca\/eng\/policy-politique_tcps2-eptc2_2022.html (accessed June 26, 2024)."},{"key":"10.1016\/j.yebeh.2024.110221_b0060","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/S0140-6736(15)00045-8","article-title":"Epilepsy in pregnancy and reproductive outcomes: a systematic review and meta-analysis","volume":"386","author":"Viale","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.yebeh.2024.110221_b0065","unstructured":"Kuang H, Li Y, Lu Y, Zhang L, Wei L, Wu Y, et al. Reproductive and fetal outcomes in women with epilepsy: a systematic review and meta-analysis. The Journal of Maternal-Fetal & Neonatal Medicine 2351;37:2351196. https:\/\/doi.org\/10.1080\/14767058.2024.2351196. Supplemental material. Table S2:3-10. https:\/\/www.tandfonline.com\/action\/downloadSupplement?doi=10.1080%2F14767058.2024.2351196&file=ijmf_a_2351196_sm5931.zip."},{"key":"10.1016\/j.yebeh.2024.110221_b0070","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1001\/jamaneurol.2015.1017","article-title":"Mortality and morbidity during delivery hospitalization among pregnant women with epilepsy in the united states","volume":"72","author":"MacDonald","year":"2015","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.yebeh.2024.110221_b0075","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1001\/jamaneurol.2024.2375","article-title":"Risk of perinatal and maternal morbidity and mortality among pregnant women with epilepsy","volume":"81","author":"Razaz","year":"2024","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.yebeh.2024.110221_bib211","doi-asserted-by":"crossref","unstructured":"Mazzone PP, Hogg KM, Weir CJ, Stephen J, Bhattacharya S, Chin RFM. Comparison of Perinatal Outcomes for Women With and Without Epilepsy: A Systematic Review and Meta-analysis. JAMA Neurol 2023;80:484\u201394. https:\/\/doi.org\/10.1001\/JAMANEUROL.2023.0148. Supplement 1. eTable 2:22-40. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10012044\/bin\/jamaneurol-e230148-s001.pdf.","DOI":"10.1001\/jamaneurol.2023.0148"},{"issue":"4","key":"10.1016\/j.yebeh.2024.110221_bib212","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S1474-4422(18)30454-X","article-title":"Global, regional, and national burden of epilepsy, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016","volume":"18","author":"GBD 2016 Epilepsy Collaborators","year":"2019","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.yebeh.2024.110221_b0080","doi-asserted-by":"crossref","unstructured":"Fisher RS, Boas W van E, Blume W, Elger C, Genton P, Lee P, et al. Epileptic Seizures and Epilepsy: Definitions Proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). Epilepsia 2005;46:470\u20132. https:\/\/doi.org\/10.1111\/j.0013-9580.2005.66104.x.","DOI":"10.1111\/j.0013-9580.2005.66104.x"},{"key":"10.1016\/j.yebeh.2024.110221_b0085","doi-asserted-by":"crossref","first-page":"e831","DOI":"10.1212\/WNL.0000000000008001","article-title":"Declining malformation rates with changed antiepileptic drug prescribing","volume":"93","author":"Tomson","year":"2019","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2024.110221_b0090","unstructured":"QuickStats: Age-Adjusted Percentages of Adults Aged \u226518 Years Who Have Epilepsy, by Epilepsy Status and Race\/Ethnicity \u2014 National Health Interview Survey, United States, 2010 and 2013 Combined MMWR n.d."},{"key":"10.1016\/j.yebeh.2024.110221_b0095","first-page":"1431","article-title":"Estimating the incidence of first unprovoked seizure and newly diagnosed epilepsy in the low-income urban community of Northern Manhattan","volume":"49","author":"Benn","year":"2008","journal-title":"New York City Epilepsia"},{"key":"10.1016\/j.yebeh.2024.110221_b0100","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1111\/epi.17313","article-title":"Association between social deprivation and incidence of first seizures and epilepsy: A prospective population-based cohort","volume":"63","author":"Maloney","year":"2022","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.110221_b0105","doi-asserted-by":"crossref","first-page":"136","DOI":"10.4103\/aam.aam_139_22","article-title":"Obesity and metabolic syndrome in patients with epilepsy, their relation with epilepsy control","volume":"22","author":"Nazish","year":"2023","journal-title":"Ann Afr Med"},{"key":"10.1016\/j.yebeh.2024.110221_b0110","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1111\/j.1528-1167.2007.01402.x","article-title":"Weight issues for people with epilepsy\u2014A review","volume":"48","author":"Ben-Menachem","year":"2007","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.110221_b0115","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.seizure.2015.07.021","article-title":"Thyroid hormones: Possible roles in epilepsy pathology","volume":"31","author":"Tamijani","year":"2015","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2024.110221_b0120","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.yebeh.2019.01.033","article-title":"Prevalence and incidence of new-onset seizures and epilepsy in patients with human immunodeficiency virus (HIV): Systematic review and meta-analysis","volume":"93","author":"Ssentongo","year":"2019","journal-title":"Epilepsy Behav"},{"key":"10.1016\/j.yebeh.2024.110221_b0125","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1186\/s12879-021-06497-7","article-title":"Seizure in HIV-infected patients: clinical presentation, cause and treatment outcome in Ethiopia\u2014a retrospective study","volume":"21","author":"Amare","year":"2021","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.yebeh.2024.110221_b0130","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s12916-024-03307-0","article-title":"Exploring the smoking-epilepsy nexus: a systematic review and meta-analysis of observational studies","volume":"22","author":"Kang","year":"2024","journal-title":"BMC Med"},{"key":"10.1016\/j.yebeh.2024.110221_b0135","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1528-1167.2012.03613.x","article-title":"Alcohol and drugs in epilepsy: Pathophysiology, presentation, possibilities, and prevention","volume":"53","author":"Leach","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.110221_b0140","doi-asserted-by":"crossref","unstructured":"Huang C yu, Dai Y mei, Feng L min, Gao W li. Clinical characteristics and outcomes in pregnant women with epilepsy. Epilepsy and Behavior 2020;112. https:\/\/doi.org\/10.1016\/j.yebeh.2020.107433.","DOI":"10.1016\/j.yebeh.2020.107433"},{"issue":"37","key":"10.1016\/j.yebeh.2024.110221_b0145","article-title":"Reproductive and fetal outcomes in women with epilepsy: a systematic review and meta-analysis","volume":"2351","author":"Kuang","year":"2024","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.yebeh.2024.110221_b0150","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1007\/s10072-019-03913-4","article-title":"Hypertension, seizures, and epilepsy: a review on pathophysiology and management","volume":"40","author":"Gasparini","year":"2019","journal-title":"Neurol Sci"},{"key":"10.1016\/j.yebeh.2024.110221_b0155","doi-asserted-by":"crossref","first-page":"7917","DOI":"10.1080\/14767058.2021.1938528","article-title":"Maternal morbidity and mortality associated with epilepsy","volume":"35","author":"Gyamfi-Bannerman","year":"2022","journal-title":"J Matern Fetal Neonatal Med"},{"key":"10.1016\/j.yebeh.2024.110221_b0160","first-page":"1","volume":"1","author":"Wolberg","year":"2015","journal-title":"Venous thrombosis Nature Reviews Disease Primers"},{"key":"10.1016\/j.yebeh.2024.110221_b0165","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1161\/HYPERTENSIONAHA.119.14280","article-title":"Hypertensive complications of pregnancy and risk of venous thromboembolism","volume":"75","author":"Scheres","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.yebeh.2024.110221_b0170","doi-asserted-by":"crossref","unstructured":"Pastori D, Cormaci VM, Marucci S, Franchino G, Del Sole F, Capozza A, et al. A Comprehensive Review of Risk Factors for Venous Thromboembolism: From Epidemiology to Pathophysiology. International Journal of Molecular Sciences 2023, Vol 24, Page 3169 2023;24:3169. https:\/\/doi.org\/10.3390\/IJMS24043169.","DOI":"10.3390\/ijms24043169"},{"key":"10.1016\/j.yebeh.2024.110221_b0175","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1042\/BST20140310","article-title":"Elevated venous thromboembolism risk in preeclampsia: molecular mechanisms and clinical impact","volume":"43","author":"Egan","year":"2015","journal-title":"Biochem Soc Trans"},{"key":"10.1016\/j.yebeh.2024.110221_b0180","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3390\/ijerph21010089","article-title":"Hypertensive disorders of pregnancy and pre-pregnancy hypertension with subsequent incident venous thromboembolic events","volume":"21","author":"Malek","year":"2024","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.yebeh.2024.110221_b0185","doi-asserted-by":"crossref","first-page":"e3287","DOI":"10.1002\/brb3.3287","article-title":"The impact of epilepsy and antiseizure medications on pregnancy and neonatal outcomes: A nationwide cohort study","volume":"13","author":"Kuo","year":"2023","journal-title":"Brain Behav"},{"key":"10.1016\/j.yebeh.2024.110221_b0190","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.1111\/j.1528-1167.2009.02147.x","article-title":"Pregnancy, delivery, and outcome for the child in maternal epilepsy","volume":"50","author":"Veiby","year":"2009","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2024.110221_b0195","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1111\/ene.13865","article-title":"Increased rate of acute caesarean sections in women with epilepsy: results from the oppland perinatal database in norway","volume":"26","author":"Farmen","year":"2019","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.yebeh.2024.110221_b0200","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1001\/jamaneurol.2017.1310","article-title":"Association between pregnancy and perinatal outcomes among women with epilepsy","volume":"74","author":"Razaz","year":"2017","journal-title":"JAMA Neurol"},{"key":"10.1016\/j.yebeh.2024.110221_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.eplepsyres.2021.106566","article-title":"Peripartum hemorrhage and other obstetric and neonatal outcomes in pregnant women with epilepsy: A single-center study","volume":"171","author":"I\u015f\u0131kalan","year":"2021","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2024.110221_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.jogoh.2020.101987","article-title":"Risks factors FOR wound complications after cesarean section","volume":"50","author":"Carbonnel","year":"2021","journal-title":"J Gynecol Obstet Hum Reprod"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505024006036?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505024006036?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,13]],"date-time":"2025-02-13T10:02:23Z","timestamp":1739440943000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505024006036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":44,"alternative-id":["S1525505024006036"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2024.110221","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal epilepsy and pregnancy, delivery and neonatal outcomes: A population-based retrospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2024.110221","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"110221"}}