{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:08:04Z","timestamp":1789013284051,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","epilepsybehavior.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Epilepsy & Behavior"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.yebeh.2026.111202","type":"journal-article","created":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T15:19:41Z","timestamp":1784387981000},"page":"111202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Childhood Absence Epilepsy with Coexisting Centrotemporal Spikes: Frequency, Electroclinical Course and Prognosis"],"prefix":"10.1016","volume":"184","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3609-2774","authenticated-orcid":false,"given":"Maria Augusta","family":"Montenegro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shifteh","family":"Sattar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8602-7700","authenticated-orcid":false,"given":"Mark","family":"Nespeca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kette","family":"Valente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yebeh.2026.111202_b0005","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1111\/epi.17236","article-title":"ILAE definition of the Idiopathic Generalized Epilepsy Syndromes: Position statement by the ILAE Task Force on Nosology and Definitions","volume":"63","author":"Hirsch","year":"2022","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2026.111202_b0010","unstructured":"Medina MT, Genton P, Bureau M, et al. Absence epilepsies. In: Bureau M, Genton, P, Fravet C, Delgado-Escueta AV, Guerrinin R, Tassinari CA, Thomas P, Wolf P (eds). Epileptic syndromes in infancy, childhood and adolescence (6th edition); John Libbey Eurotext Ltd 2019; pp:285-320."},{"key":"10.1016\/j.yebeh.2026.111202_b0015","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.ejpn.2017.02.002","article-title":"Coexistence of childhood absence epilepsy and benign epilepsy with centrotemporal spikes: a case series","volume":"21","author":"Verrotti","year":"2017","journal-title":"Eur J Paediatr Neurol"},{"key":"10.1016\/j.yebeh.2026.111202_b0020","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1007\/s12519-017-0006-9","article-title":"Childhood absence epilepsy and benign epilepsy with centro-temporal spikes: a narrative review analysis","volume":"13","author":"Verrotti","year":"2017","journal-title":"World J Pediatr"},{"key":"10.1016\/j.yebeh.2026.111202_b0025","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1177\/0883073819848639","article-title":"Clinical significance of incidental rolandic spikes in children with absence epilepsy","volume":"34","author":"Datta","year":"2019","journal-title":"J Child Neurol"},{"key":"10.1016\/j.yebeh.2026.111202_b0030","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1177\/155005949802900409","article-title":"Concomitance of childhood absence and Rolandic epilepsy","volume":"29","author":"Ramelli","year":"1998","journal-title":"Clin Electroencephalogr"},{"key":"10.1016\/j.yebeh.2026.111202_b0035","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1177\/08830738060210062301","article-title":"Coexistence of childhood absence and rolandic epilepsy","volume":"21","author":"Montenegro","year":"2006","journal-title":"J Child Neurol"},{"key":"10.1016\/j.yebeh.2026.111202_b0040","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.seizure.2011.09.005","article-title":"Two epileptic syndromes, one brain: childhood absence epilepsy and benign childhood epilepsy with centrotemporal spikes","volume":"21","author":"Cerminara","year":"2012","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2026.111202_b0045","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/epd2.70044","article-title":"Co-occurrence of childhood absence epilepsy and self-limited focal epilepsy interictal discharges: differences from childhood absence epilepsy alone","volume":"27","author":"Barbagallo","year":"2025","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.yebeh.2026.111202_b0050","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/ana.410130610","article-title":"Long-term prognosis in two forms of childhood epilepsy: typical absence seizures and epilepsy with rolandic (centrotemporal) EEG foci","volume":"13","author":"Loiseau","year":"1983","journal-title":"Ann Neurol"},{"key":"10.1016\/j.yebeh.2026.111202_b0055","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.eplepsyres.2019.02.013","article-title":"Historical trend toward improved long-term outcome in childhood absence epilepsy","volume":"152","author":"Morse","year":"2019","journal-title":"Epilepsy Res"},{"key":"10.1016\/j.yebeh.2026.111202_b0060","first-page":"1452","article-title":"Clinical and instrumental follow-up of childhood absence epilepsy (CAE): exploration of prognostic factors","volume":"9","author":"Amianto","year":"2022","journal-title":"Children (Basel)"},{"key":"10.1016\/j.yebeh.2026.111202_b0065","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1046\/j.1528-1157.2001.02401.x","article-title":"Prognostic significance of failure of the initial antiepileptic drug in children with absence epilepsy","volume":"42","author":"Wirrell","year":"2001","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2026.111202_b0070","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.nrl.2016.12.005","article-title":"Long-term prognosis of childhood absence epilepsy","volume":"34","author":"Mart\u00ednez-Ferr\u00e1ndez","year":"2019","journal-title":"Neurologia (Engl Ed)"},{"key":"10.1016\/j.yebeh.2026.111202_b0075","first-page":"85","article-title":"Long-term Prognosis of Childhood Absence Epilepsy","volume":"61","author":"Ya\u015fg\u00fc\u00e7l\u00fckal","year":"2024","journal-title":"Noro Psikiyatr Ars"},{"key":"10.1016\/j.yebeh.2026.111202_b0080","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1111\/j.1528-1167.2012.03723.x","article-title":"The prognosis of idiopathic generalized epilepsy","volume":"53","author":"Seneviratne","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2026.111202_b0085","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1056\/NEJMoa0902014","article-title":"Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy","volume":"362","author":"Glauser","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1016\/j.yebeh.2026.111202_b0090","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1111\/j.1468-1331.2006.01464.x","article-title":"Oxcarbazepine and atypical evolution of benign idiopathic focal epilepsy of childhood","volume":"13","author":"Grosso","year":"2006","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.yebeh.2026.111202_b0095","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1053\/seiz.2001.0568","article-title":"Phenobarbital-induced atypical absence seizure in benign childhood epilepsy with centrotemporal spikes","volume":"11","author":"Hamano","year":"2002","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2026.111202_b0100","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1111\/j.1528-1157.1999.tb02053.x","article-title":"Paradoxic reaction to lamotrigine in a child with benign focal epilepsy of childhood with centrotemporal spikes","volume":"40","author":"Catania","year":"1999","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2026.111202_b0105","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1007\/s12519-018-0148-4","article-title":"Consecutive occurrence of benign epilepsy with centro-temporal spike and childhood absence epilepsy: true coexistence or atypical evolution?","volume":"14","author":"Lee","year":"2018","journal-title":"World J Pediatr"},{"key":"10.1016\/j.yebeh.2026.111202_b0110","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.pediatrneurol.2005.03.001","article-title":"Aggravation of epilepsy by antiepileptic drugs","volume":"33","author":"Sazgar","year":"2005","journal-title":"Pediatr Neurol"},{"key":"10.1016\/j.yebeh.2026.111202_b0115","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1212\/01.wnl.0000228257.60184.82","article-title":"Electroclinical features of absence seizures in childhood absence epilepsy","volume":"67","author":"Sadleir","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2026.111202_b0120","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1212\/WNL.0b013e31829a3373","article-title":"Pretreatment EEG in childhood absence epilepsy: associations with attention and treatment outcome","volume":"81","author":"Dlugos","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.yebeh.2026.111202_b0125","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1111\/j.1528-1157.1995.tb01060.x","article-title":"Absence epilepsies","volume":"36","author":"Loiseau","year":"1995","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2026.111202_b0130","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1684\/j.1950-6945.2006.tb00154.x","article-title":"Cognitive functions in children with benign childhood epilepsy with centrotemporal spikes (BECTS)","volume":"8","author":"Pinton","year":"2006","journal-title":"Epileptic Disord"},{"key":"10.1016\/j.yebeh.2026.111202_b0135","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.seizure.2016.11.031","article-title":"Absence epilepsy: continuum of clinical presentation and epigenetics?","volume":"44","author":"Guilhoto","year":"2017","journal-title":"Seizure"},{"key":"10.1016\/j.yebeh.2026.111202_b0140","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1111\/epi.13865","article-title":"Cognitive functioning in children with self-limited epilepsy with centrotemporal spikes: a systematic review and meta-analysis","volume":"58","author":"Wickens","year":"2017","journal-title":"Epilepsia"},{"key":"10.1016\/j.yebeh.2026.111202_b0145","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.3389\/fneur.2019.01316","article-title":"Mapping the effect of interictal epileptic activity density during wakefulness on brain functioning in focal childhood epilepsies with centrotemporal spikes","volume":"10","author":"Vaudano","year":"2019","journal-title":"Front Neurol"},{"key":"10.1016\/j.yebeh.2026.111202_b0150","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1523\/JNEUROSCI.2009-20.2020","article-title":"Focal sleep spindle deficits reveal focal thalamocortical dysfunction and predict cognitive deficits in sleep activated developmental epilepsy","volume":"41","author":"Kramer","year":"2021","journal-title":"J Neurosci"}],"container-title":["Epilepsy & Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505026003239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1525505026003239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:26:44Z","timestamp":1789010804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525505026003239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":30,"alternative-id":["S1525505026003239"],"URL":"https:\/\/doi.org\/10.1016\/j.yebeh.2026.111202","relation":{},"ISSN":["1525-5050"],"issn-type":[{"value":"1525-5050","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Childhood Absence Epilepsy with Coexisting Centrotemporal Spikes: Frequency, Electroclinical Course and Prognosis","name":"articletitle","label":"Article Title"},{"value":"Epilepsy & Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yebeh.2026.111202","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"111202"}}