{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:07:01Z","timestamp":1788268021099,"version":"build-2803163510"},"reference-count":49,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Cell Research"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.yexcr.2004.10.012","type":"journal-article","created":{"date-parts":[[2004,12,15]],"date-time":"2004-12-15T04:14:09Z","timestamp":1103084049000},"page":"375-387","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing"],"prefix":"10.1016","volume":"303","author":[{"given":"Hiroshi","family":"Maita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hirotake","family":"Kitaura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyoshi","family":"Ariga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanae M.M.","family":"Iguchi-Ariga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yexcr.2004.10.012_bib1","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0092-8674(94)90182-1","article-title":"Splicing of Balbiani ring 1 gene pre-mRNA occurs simultaneously with transcription","volume":"76","author":"Bauren","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1006\/excr.1996.0358","article-title":"Nuclear organization and gene expression","volume":"229","author":"Spector","year":"1996","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.yexcr.2004.10.012_bib3","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1038\/372809a0","article-title":"Localization of pre-mRNA splicing in mammalian nuclei","volume":"372","author":"Zhang","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.yexcr.2004.10.012_bib4","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1101\/gad.11.9.1148","article-title":"Distribution of pre-mRNA splicing factors at sites of RNA polymerase II transcription","volume":"11","author":"Neugebauer","year":"1997","journal-title":"Genes Dev."},{"key":"10.1016\/j.yexcr.2004.10.012_bib5","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/nrm1172","article-title":"Nuclear speckles: a model for nuclear organelles","volume":"4","author":"Lamond","year":"2003","journal-title":"Nat. Rev., Mol. Cell Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1097-2765(00)80372-X","article-title":"Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2\/ASF and 9G8 effects on an exonic splicing enhancer","volume":"4","author":"Cramer","year":"1999","journal-title":"Mol. Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib7","doi-asserted-by":"crossref","first-page":"11456","DOI":"10.1073\/pnas.94.21.11456","article-title":"Functional association between promoter structure and transcript alternative splicing","volume":"94","author":"Cramer","year":"1997","journal-title":"Proc. Natl. Acad. Sci.U. S. A."},{"key":"10.1016\/j.yexcr.2004.10.012_bib8","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1126\/science.1073734","article-title":"Coordinate regulation of transcription and splicing by steroid receptor coregulators","volume":"298","author":"Auboeuf","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.yexcr.2004.10.012_bib9","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1074\/jbc.M209676200","article-title":"Promoter architecture modulates CFTR exon 9 skipping","volume":"278","author":"Pagani","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2004.10.012_bib10","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S1097-2765(00)00031-9","article-title":"Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1","volume":"6","author":"Monsalve","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib11","doi-asserted-by":"crossref","first-page":"5168","DOI":"10.1046\/j.1432-1327.2000.01585.x","article-title":"PAP-1, a novel target protein of phosphorylation by pim-1 kinase","volume":"267","author":"Maita","year":"2000","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.yexcr.2004.10.012_bib12","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/sj.ejhg.5200797","article-title":"Mutations in a protein target of the Pim-1 kinase associated with the RP9 form of autosomal dominant retinitis pigmentosa","volume":"10","author":"Keen","year":"2002","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.yexcr.2004.10.012_bib13","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.yexcr.2004.07.029","article-title":"PAP-1, the mutated gene underlying the RP9 form of dominant retinitis pigmentosa, is a splicing factor","volume":"300","author":"Maita","year":"2004","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.yexcr.2004.10.012_bib14","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.yexcr.2004.08.022","article-title":"Association of PAP-1 and Prp3p, the products of causative genes of dominant retinitis pigmentosa, in the tri-snRNP complex","volume":"302","author":"Maita","year":"2004","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.yexcr.2004.10.012_bib15","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1073\/pnas.96.1.23","article-title":"CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex","volume":"96","author":"Hsieh","year":"1999","journal-title":"Proc. Natl. Acad. Sci.U. S. A."},{"key":"10.1016\/j.yexcr.2004.10.012_bib16","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1128\/JVI.74.4.1939-1947.2000","article-title":"A role for SKIP in EBNA2 activation of CBF1-repressed promoters","volume":"74","author":"Zhou","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib17","doi-asserted-by":"crossref","first-page":"6222","DOI":"10.1128\/MCB.21.18.6222-6232.2001","article-title":"Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex","volume":"21","author":"Zhou","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib18","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1101\/gad.10.13.1569","article-title":"SR proteins and splicing control","volume":"10","author":"Manley","year":"1996","journal-title":"Genes Dev."},{"key":"10.1016\/j.yexcr.2004.10.012_bib19","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/S0968-0004(96)10039-6","article-title":"The SR protein family: pleiotropic functions in pre-mRNA splicing","volume":"21","author":"Valcarcel","year":"1996","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.yexcr.2004.10.012_bib20","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1017\/S1355838200000960","article-title":"Sorting out the complexity of SR protein functions","volume":"6","author":"Graveley","year":"2000","journal-title":"RNA"},{"key":"10.1016\/j.yexcr.2004.10.012_bib21","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1101\/gad.12.1.55","article-title":"A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm","volume":"12","author":"Caceres","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/j.yexcr.2004.10.012_bib22","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/S1097-2765(01)00233-7","article-title":"Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA","volume":"7","author":"Huang","year":"2001","journal-title":"Mol. Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib23","doi-asserted-by":"crossref","first-page":"E201","DOI":"10.1038\/ncb0901-e201","article-title":"A new view of mRNA export: separating the wheat from the chaff","volume":"3","author":"Reed","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib24","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0092-8674(91)90185-2","article-title":"Arginine\/serine-rich domains of the su(wa) and tra RNA processing regulators target proteins to a subnuclear compartment implicated in splicing","volume":"67","author":"Li","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib25","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1093\/emboj\/20.10.2553","article-title":"The 65 and 110 kDa SR-related proteins of the U4\/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes","volume":"20","author":"Makarova","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.yexcr.2004.10.012_bib26","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.1128\/MCB.20.9.3049-3057.2000","article-title":"Identification and characterization of a novel serine\u2013arginine-rich splicing regulatory protein","volume":"20","author":"Barnard","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib27","doi-asserted-by":"crossref","first-page":"11832","DOI":"10.1074\/jbc.274.17.11832","article-title":"A human papillomavirus E2 transcriptional activator. The interactions with cellular splicing factors and potential function in pre-mRNA processing","volume":"274","author":"Lai","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2004.10.012_bib28","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1083\/jcb.200010059","article-title":"ZNF265\u2014a novel spliceosomal protein able to induce alternative splicing","volume":"154","author":"Adams","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib29","doi-asserted-by":"crossref","first-page":"5717","DOI":"10.1073\/pnas.97.11.5717","article-title":"A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection","volume":"97","author":"Elliott","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.yexcr.2004.10.012_bib30","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/0042-6822(73)90341-3","article-title":"A new technique for the assay of infectivity of human adenovirus 5 DNA","volume":"52","author":"Graham","year":"1973","journal-title":"Virology"},{"key":"10.1016\/j.yexcr.2004.10.012_bib31","doi-asserted-by":"crossref","first-page":"29794","DOI":"10.1074\/jbc.273.45.29794","article-title":"MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc","volume":"273","author":"Mori","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2004.10.012_bib32","doi-asserted-by":"crossref","first-page":"31145","DOI":"10.1074\/jbc.M003031200","article-title":"TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase","volume":"275","author":"Ono","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2004.10.012_bib33","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1126\/science.8085156","article-title":"Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors","volume":"265","author":"Caceres","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.yexcr.2004.10.012_bib34","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.gene.2004.05.025","article-title":"A novel nucleolar protein, PAPA-1, induces growth arrest as a result of cell cycle arrest at the G1 phase","volume":"340","author":"Kuroda","year":"2004","journal-title":"Gene"},{"key":"10.1016\/j.yexcr.2004.10.012_bib35","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/343437a0","article-title":"Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus","volume":"343","author":"Fu","year":"1990","journal-title":"Nature"},{"key":"10.1016\/j.yexcr.2004.10.012_bib36","doi-asserted-by":"crossref","first-page":"E85","DOI":"10.1038\/35010583","article-title":"The transcriptional role of PML and the nuclear body","volume":"2","author":"Zhong","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib37","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/1700","article-title":"Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex","volume":"20","author":"Neubauer","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.yexcr.2004.10.012_bib38","doi-asserted-by":"crossref","first-page":"4308","DOI":"10.1093\/emboj\/18.15.4308","article-title":"Purification and biochemical characterization of interchromatin granule clusters","volume":"18","author":"Mintz","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.yexcr.2004.10.012_bib39","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1083\/jcb.143.2.297","article-title":"Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo","volume":"143","author":"Misteli","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib40","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0092-8674(94)90196-1","article-title":"The suppressor of hairless protein participates in notch receptor signaling","volume":"79","author":"Fortini","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib41","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1128\/MCB.16.3.952","article-title":"Truncated mammalian Notch1 activates CBF1\/RBPJk-repressed genes by a mechanism resembling that of Epstein\u2013Barr virus EBNA2","volume":"16","author":"Hsieh","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.yexcr.2004.10.012_bib42","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0092-8674(00)80216-0","article-title":"Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex","volume":"89","author":"Zhang","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib43","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/S1097-2765(00)80102-1","article-title":"SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex","volume":"1","author":"Zhang","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib44","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1097-2765(00)80111-2","article-title":"SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors","volume":"2","author":"Laherty","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/j.yexcr.2004.10.012_bib45","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1038\/sj.onc.1201687","article-title":"The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42","volume":"16","author":"Dahl","year":"1998","journal-title":"Oncogene"},{"key":"10.1016\/j.yexcr.2004.10.012_bib46","doi-asserted-by":"crossref","first-page":"16434","DOI":"10.1074\/jbc.273.26.16434","article-title":"Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription","volume":"273","author":"Baudino","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2004.10.012_bib47","doi-asserted-by":"crossref","first-page":"35325","DOI":"10.1074\/jbc.M305191200","article-title":"Nuclear coactivator-62 kDa\/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing","volume":"278","author":"Zhang","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2004.10.012_bib48","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.bbrc.2004.02.077","article-title":"SKIP modifies gene expression by affecting both transcription and splicing","volume":"316","author":"Nagai","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.yexcr.2004.10.012_bib49","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1006\/bbrc.2001.5108","article-title":"The fission yeast ortholog of the coregulator SKIP interacts with the small subunit of U2AF","volume":"284","author":"Ambrozkova","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Experimental Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482704005890?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482704005890?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T03:43:44Z","timestamp":1757994224000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014482704005890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0014482704005890"],"URL":"https:\/\/doi.org\/10.1016\/j.yexcr.2004.10.012","relation":{},"ISSN":["0014-4827"],"issn-type":[{"value":"0014-4827","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CIR, a corepressor of CBF1, binds to PAP-1 and effects alternative splicing","name":"articletitle","label":"Article Title"},{"value":"Experimental Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yexcr.2004.10.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}