{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:58:55Z","timestamp":1792591135083,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006313","name":"Barncancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006313","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Cell Research"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.yexcr.2009.07.001","type":"journal-article","created":{"date-parts":[[2009,7,9]],"date-time":"2009-07-09T04:39:29Z","timestamp":1247114369000},"page":"2941-2952","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":152,"title":["DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1"],"prefix":"10.1016","volume":"315","author":[{"given":"Mikael","family":"Lerner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masako","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Lov\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zadie","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Oscier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Henriksson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olle","family":"Sangfelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Grand\u00e9r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin M.","family":"Corcoran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yexcr.2009.07.001_bib1","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/nrm2395","article-title":"Transcriptional control of human p53-regulated genes","volume":"9","author":"Riley","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib2","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1007\/s00018-007-7447-6","article-title":"Post-transcriptional gene regulation: from genome-wide studies to principles","volume":"65","author":"Halbeisen","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.yexcr.2009.07.001_bib3","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1046\/j.1468-0734.2000.00003.x","article-title":"Genetic features of B-cell chronic lymphocytic leukemia","volume":"4","author":"Stilgenbauer","year":"2000","journal-title":"Rev. Clin. Exp. Hematol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib4","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1182\/blood-2003-12-4175","article-title":"Genomic DNA-chip hybridization in t(11;14)-positive mantle cell lymphomas shows a high frequency of aberrations and allows a refined characterization of consensus regions","volume":"104","author":"Kohlhammer","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.yexcr.2009.07.001_bib5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3109\/10428190109097656","article-title":"Secondary chromosome changes in mantle cell lymphoma: cytogenetic and fluorescence in situ hybridization studies","volume":"40","author":"Bigoni","year":"2001","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.yexcr.2009.07.001_bib6","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1046\/j.1365-2141.2003.04172.x","article-title":"Cytogenetics of multiple myeloma: interpretation of fluorescence in situ hybridization results","volume":"120","author":"Harrison","year":"2003","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib7","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1002\/(SICI)1097-0215(19980821)79:4<312::AID-IJC2>3.0.CO;2-Y","article-title":"Allelic loss of chromosome 13q14.3 in human oral cancer: correlation with lymph node metastasis","volume":"79","author":"Ogawara","year":"1998","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.yexcr.2009.07.001_bib8","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.cancergencyto.2007.08.017","article-title":"Allelic imbalance at 13q14.2 approximately q14.3 in localized prostate cancer is associated with early biochemical relapse","volume":"179","author":"Brookman-Amissah","year":"2007","journal-title":"Cancer Genet. Cytogenet."},{"key":"10.1016\/j.yexcr.2009.07.001_bib9","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1038\/sj.onc.1201643","article-title":"Cloning of two candidate tumor suppressor genes within a 10\u00a0kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia","volume":"15","author":"Liu","year":"1997","journal-title":"Oncogene"},{"key":"10.1016\/j.yexcr.2009.07.001_bib10","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1006\/geno.2000.6386","article-title":"Comparative sequence analysis of a region on human chromosome 13q14, frequently deleted in B-cell chronic lymphocytic leukemia, and its homologous region on mouse chromosome 14","volume":"70","author":"Kapanadze","year":"2000","journal-title":"Genomics"},{"key":"10.1016\/j.yexcr.2009.07.001_bib11","doi-asserted-by":"crossref","first-page":"15524","DOI":"10.1073\/pnas.242606799","article-title":"Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia","volume":"99","author":"Calin","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.yexcr.2009.07.001_bib12","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1128\/MCB.02005-06","article-title":"Transcripts targeted by the microRNA-16 family cooperatively regulate cell cycle progression","volume":"27","author":"Linsley","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib13","series-title":"Molecular Cloning: A Laboratory Manual","author":"Sambrook","year":"2001"},{"key":"10.1016\/j.yexcr.2009.07.001_bib14","doi-asserted-by":"crossref","first-page":"13887","DOI":"10.1073\/pnas.95.23.13887","article-title":"c-Myc target gene specificity is determined by a post-DNA binding mechanism","volume":"95","author":"Boyd","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.yexcr.2009.07.001_bib15","first-page":"476","article-title":"Epstein\u2013Barr virus (EBV) can immortalize B-cll cells activated by cytokines","volume":"8","author":"Wendel-Hansen","year":"1994","journal-title":"Leukemia"},{"key":"10.1016\/j.yexcr.2009.07.001_bib16","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1091\/mbc.e06-03-0248","article-title":"The RBCC gene RFP2 (Leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD","volume":"18","author":"Lerner","year":"2007","journal-title":"Mol. Biol. Cell."},{"key":"10.1016\/j.yexcr.2009.07.001_bib17","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/sj.emboj.7601512","article-title":"Processing of intronic microRNAs","volume":"26","author":"Kim","year":"2007","journal-title":"Embo J."},{"key":"10.1016\/j.yexcr.2009.07.001_bib18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/ng.2007.30","article-title":"Widespread microRNA repression by Myc contributes to tumorigenesis","volume":"40","author":"Chang","year":"2008","journal-title":"Nat. Genet."},{"key":"10.1016\/j.yexcr.2009.07.001_bib19","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/1097-0215(20000915)87:6<787::AID-IJC4>3.0.CO;2-6","article-title":"Cell cycle activation by c-myc in a Burkitt lymphoma model cell line","volume":"87","author":"Pajic","year":"2000","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.yexcr.2009.07.001_bib20","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.cell.2007.05.009","article-title":"High-resolution profiling of histone methylations in the human genome","volume":"129","author":"Barski","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.yexcr.2009.07.001_bib21","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1038\/nmeth1130","article-title":"Using expression profiling data to identify human microRNA targets","volume":"4","author":"Huang","year":"2007","journal-title":"Nat. Methods"},{"key":"10.1016\/j.yexcr.2009.07.001_bib22","doi-asserted-by":"crossref","first-page":"4182","DOI":"10.1002\/j.1460-2075.1996.tb00793.x","article-title":"Activation of cyclin E\/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E","volume":"15","author":"Won","year":"1996","journal-title":"Embo J."},{"key":"10.1016\/j.yexcr.2009.07.001_bib23","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/35095076","article-title":"Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line","volume":"413","author":"Strohmaier","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.yexcr.2009.07.001_bib24","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1038\/nrm1246","article-title":"Ratchets and clocks: the cell cycle, ubiquitylation and protein turnover","volume":"4","author":"Reed","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib25","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/1471-2164-8-166","article-title":"Characterization of microRNA expression profiles in normal human tissues","volume":"8","author":"Liang","year":"2007","journal-title":"BMC Genomics"},{"key":"10.1016\/j.yexcr.2009.07.001_bib26","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1038\/nm.1880","article-title":"The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities","volume":"14","author":"Bonci","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.yexcr.2009.07.001_bib27","doi-asserted-by":"crossref","first-page":"R214","DOI":"10.1186\/gb-2007-8-10-r214","article-title":"MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype","volume":"8","author":"Blenkiron","year":"2007","journal-title":"Genome Biol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib28","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1002\/ijc.23501","article-title":"miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells","volume":"123","author":"Xia","year":"2008","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.yexcr.2009.07.001_bib29","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1210\/jc.2008-1451","article-title":"MicroRNAs differentially expressed in ACTH-secreting pituitary tumors","volume":"94","author":"Amaral","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.yexcr.2009.07.001_bib30","doi-asserted-by":"crossref","DOI":"10.4161\/cbt.7.11.6722","article-title":"c-Myb oncoprotein is an essential target of the dleu2 tumor suppressor microRNA cluster","volume":"7","author":"Chung","year":"2008","journal-title":"Cancer Biol. Ther."},{"key":"10.1016\/j.yexcr.2009.07.001_bib31","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/gcc.20046","article-title":"DLEU2 encodes an antisense RNA for the putative bicistronic RFP2\/LEU5 gene in humans and mouse","volume":"40","author":"Corcoran","year":"2004","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1016\/j.yexcr.2009.07.001_bib32","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1080\/10428190902763509","article-title":"Chronic lymphocytic leukemia and 13q14: miRs and more","volume":"50","author":"Mertens","year":"2009","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.yexcr.2009.07.001_bib33","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1006\/geno.1997.4747","article-title":"Cloning and gene mapping of the chromosome 13q14 region deleted in chronic lymphocytic leukemia","volume":"42","author":"Kalachikov","year":"1997","journal-title":"Genomics"},{"key":"10.1016\/j.yexcr.2009.07.001_bib34","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1158\/0008-5472.CAN-07-3105","article-title":"Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14","volume":"68","author":"Ouillette","year":"2008","journal-title":"Cancer Res."},{"key":"10.1016\/j.yexcr.2009.07.001_bib35","doi-asserted-by":"crossref","first-page":"13944","DOI":"10.1073\/pnas.0506654102","article-title":"miR-15 and miR-16 induce apoptosis by targeting BCL2","volume":"102","author":"Cimmino","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.yexcr.2009.07.001_bib36","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1261\/rna.1301109","article-title":"The VEGF IRESes are differentially susceptible to translation inhibition by miR-16","volume":"15","author":"Karaa","year":"2009","journal-title":"Rna"},{"key":"10.1016\/j.yexcr.2009.07.001_bib37","doi-asserted-by":"crossref","first-page":"36221","DOI":"10.1074\/jbc.M806322200","article-title":"Distinct roles of heterogeneous nuclear ribonuclear protein K and microRNA-16 in cyclooxygenase-2 RNA stability induced by S100b, a ligand of the receptor for advanced glycation end products","volume":"283","author":"Shanmugam","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2009.07.001_bib38","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.cell.2004.12.038","article-title":"Involvement of microRNA in AU-rich element-mediated mRNA instability","volume":"120","author":"Jing","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.yexcr.2009.07.001_bib39","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1038\/sj.onc.1208618","article-title":"Cyclins and cdks in development and cancer: a perspective","volume":"24","author":"Deshpande","year":"2005","journal-title":"Oncogene"},{"key":"10.1016\/j.yexcr.2009.07.001_bib40","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0304-3835(94)03676-A","article-title":"Amplification of chromosome band 11q13 and a role for cyclin D1 in human breast cancer","volume":"90","author":"Dickson","year":"1995","journal-title":"Cancer Lett."},{"key":"10.1016\/j.yexcr.2009.07.001_bib41","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1038\/nrc2230","article-title":"Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics","volume":"7","author":"Jares","year":"2007","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.yexcr.2009.07.001_bib42","doi-asserted-by":"crossref","first-page":"9006","DOI":"10.1158\/0008-5472.CAN-07-1320","article-title":"FBXW7\/hCDC4 is a general tumor suppressor in human cancer","volume":"67","author":"Akhoondi","year":"2007","journal-title":"Cancer Res."},{"key":"10.1016\/j.yexcr.2009.07.001_bib43","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0959-437X(99)00049-0","article-title":"Proteolysis and the cell cycle: with this RING I do thee destroy","volume":"10","author":"Tyers","year":"2000","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.yexcr.2009.07.001_bib44","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.molcel.2006.09.007","article-title":"Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex","volume":"24","author":"Lin","year":"2006","journal-title":"Mol. Cell"},{"key":"10.1016\/j.yexcr.2009.07.001_bib45","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1128\/MCB.01977-07","article-title":"MicroRNAs in the miR-106b family regulate p21\/CDKN1A and promote cell cycle progression","volume":"28","author":"Ivanovska","year":"2008","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib46","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1038\/sj.emboj.7601790","article-title":"Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation","volume":"26","author":"le Sage","year":"2007","journal-title":"Embo J."},{"key":"10.1016\/j.yexcr.2009.07.001_bib47","doi-asserted-by":"crossref","first-page":"23716","DOI":"10.1074\/jbc.M701805200","article-title":"miR-221 and miR-222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1","volume":"282","author":"Galardi","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.yexcr.2009.07.001_bib48","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1182\/blood-2008-03-142182","article-title":"Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma","volume":"112","author":"Chen","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.yexcr.2009.07.001_bib49","doi-asserted-by":"crossref","first-page":"5391","DOI":"10.1093\/nar\/gkn522","article-title":"miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes","volume":"36","author":"Liu","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.yexcr.2009.07.001_bib50","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/S0960-9822(03)00297-5","article-title":"Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression","volume":"13","author":"Mao","year":"2003","journal-title":"Curr. Biol."},{"key":"10.1016\/j.yexcr.2009.07.001_bib51","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/0092-8674(91)90101-4","article-title":"Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle","volume":"65","author":"Matsushime","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.yexcr.2009.07.001_bib52","doi-asserted-by":"crossref","first-page":"5321","DOI":"10.1093\/emboj\/18.19.5321","article-title":"Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27","volume":"18","author":"Bouchard","year":"1999","journal-title":"Embo J."}],"container-title":["Experimental Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482709003024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482709003024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:09:49Z","timestamp":1762146589000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014482709003024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":52,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0014482709003024"],"URL":"https:\/\/doi.org\/10.1016\/j.yexcr.2009.07.001","relation":{},"ISSN":["0014-4827"],"issn-type":[{"value":"0014-4827","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1","name":"articletitle","label":"Article Title"},{"value":"Experimental Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yexcr.2009.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}