{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T01:25:12Z","timestamp":1792632312149,"version":"4.5.0"},"reference-count":77,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T00:00:00Z","timestamp":1617062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003549","name":"Hungarian Scientific Research Fund","doi-asserted-by":"publisher","award":["115394\/K"],"award-info":[{"award-number":["115394\/K"]}],"id":[{"id":"10.13039\/501100003549","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Cell Research"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.yexcr.2021.112583","type":"journal-article","created":{"date-parts":[[2021,3,31]],"date-time":"2021-03-31T15:42:57Z","timestamp":1617205377000},"page":"112583","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Fractalkine enhances endometrial receptivity and activates iron transport towards trophoblast cells in an in vitro co-culture system of HEC-1A and JEG-3\u00a0cells"],"prefix":"10.1016","volume":"403","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5012-3242","authenticated-orcid":false,"given":"Edina","family":"Pandur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram\u00f3na","family":"Pap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gergely","family":"Montsk\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gergely","family":"J\u00e1nosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Sipos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor L.","family":"Kov\u00e1cs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yexcr.2021.112583_bib1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/978-3-319-15856-3_10","article-title":"Implantation and establishment of pregnancy in human and nonhuman primates","volume":"216","author":"Su","year":"2015","journal-title":"Adv. Anat. Embryol. Cell Biol."},{"key":"10.1016\/j.yexcr.2021.112583_bib2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.12717\/DR.2017.21.4.351","article-title":"A review of mechanisms of implantation","volume":"21","author":"Kim","year":"2017","journal-title":"Dev. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib3","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1749-6632.1994.tb21743.x","article-title":"The role of leukemia inhibitory factor (LIF) and other cytokines in regulating implantation in mammals","volume":"734","author":"Stewart","year":"1994","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.yexcr.2021.112583_bib4","doi-asserted-by":"crossref","first-page":"3822","DOI":"10.3390\/ijms20153822","article-title":"Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?","volume":"20","author":"Marquardt","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.yexcr.2021.112583_bib5","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1002\/dvdy.23991","article-title":"Morphogenetic analysis of peri-implantation development","volume":"242","author":"Wallingford","year":"2013","journal-title":"Dev. Dynam."},{"key":"10.1016\/j.yexcr.2021.112583_bib6","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.tem.2018.04.001","article-title":"Progesterone receptor regulation of uterine adaptation for pregnancy","volume":"29","author":"Wu","year":"2018","journal-title":"Trends Endocrinol. Metabol."},{"key":"10.1016\/j.yexcr.2021.112583_bib7","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/humupd\/dml004","article-title":"Endometrial receptivity markers, the journey to successful embryo implantation","volume":"12","author":"Achache","year":"2006","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.yexcr.2021.112583_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep24171","article-title":"Mouse Sox17 haploinsufficiency leads to female subfertility due to impaired implantation","volume":"6","author":"Hirate","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.yexcr.2021.112583_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-51751-3","article-title":"Uterine SOX17: a key player in human endometrial receptivity and embryo implantation","volume":"9","author":"Kinnear","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.yexcr.2021.112583_bib10","first-page":"1","article-title":"SOX17 regulates uterine epithelial\u2013stromal cross-talk acting via a distal enhancer upstream of Ihh","volume":"9","author":"Wang","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.yexcr.2021.112583_bib11","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1210\/me.2011-1355","article-title":"Research resource: genome-wide profiling of progesterone receptor binding in the mouse uterus","volume":"26","author":"Rubel","year":"2012","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.yexcr.2021.112583_bib12","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/humupd\/dmi023","article-title":"Cytokines, chemokines and growth factors in endometrium related to implantation","volume":"11","author":"Dimitriadis","year":"2005","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.yexcr.2021.112583_bib13","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/jnr.10304","article-title":"Fractalkine and fractalkine receptors in human neurons and glial cells","volume":"69","author":"Hatori","year":"2002","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.yexcr.2021.112583_bib14","doi-asserted-by":"crossref","first-page":"7478","DOI":"10.4049\/jimmunol.179.11.7478","article-title":"Dose-dependent differential regulation of cytokine secretion from macrophages by fractalkine","volume":"179","author":"Mizutani","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib15","doi-asserted-by":"crossref","first-page":"6119","DOI":"10.1210\/jc.2003-031379","article-title":"Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodeling","volume":"89","author":"Hannan","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.yexcr.2021.112583_bib16","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1477-7827-9-95","article-title":"Fractalkine is expressed in the human ovary and increases progesterone biosynthesis in human luteinised granulosa cells","volume":"9","author":"Huang","year":"2011","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.yexcr.2021.112583_bib17","doi-asserted-by":"crossref","first-page":"RC87","DOI":"10.1523\/JNEUROSCI.20-15-j0004.2000","article-title":"Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage","volume":"20","author":"Chapman","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yexcr.2021.112583_bib18","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s10555-019-09807-3","article-title":"Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors","volume":"38","author":"Bronger","year":"2019","journal-title":"Canc. Metastasis Rev."},{"key":"10.1016\/j.yexcr.2021.112583_bib19","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.3390\/cells9102277","article-title":"The impact of the CX3CL1\/CX3CR1 Axis in neurological disorders","volume":"9","author":"Pawelec","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.yexcr.2021.112583_bib20","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/cmi.2014.116","article-title":"Differential expression of the fractalkine chemokine receptor (CX 3 CR1) in human monocytes during differentiation","volume":"12","author":"Panek","year":"2015","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib21","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1002\/(SICI)1521-4141(199805)28:05<1516::AID-IMMU1516>3.0.CO;2-J","article-title":"A lymphocyte-specific CC chemokine, secondary lymphoid tissue chemokine (SLC), is a highly efficient chemoattractant for B cells and activated T cells","volume":"28","author":"Nagira","year":"1998","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib22","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1095\/biolreprod.105.045518","article-title":"The chemokines, CX3CL1, CCL14, and CCL4, promote human trophoblast migration at the feto-maternal interface","volume":"74","author":"Hannan","year":"2006","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib23","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1517\/14728220903540265","article-title":"Fractalkine\/CX3CR1: why a single chemokine-receptor duo bears a major and unique therapeutic potential","volume":"14","author":"D'Haese","year":"2010","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.yexcr.2021.112583_bib24","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/19336918.2015.1089378","article-title":"The role of CX3CL1 in fetal-maternal interaction during human gestation","volume":"10","author":"Kervancioglu Demirci","year":"2016","journal-title":"Cell Adhes. Migrat."},{"key":"10.1016\/j.yexcr.2021.112583_bib25","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1016\/j.ajpath.2015.01.019","article-title":"Placental fractalkine is up-regulated in severe early-onset preeclampsia","volume":"185","author":"Siwetz","year":"2015","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yexcr.2021.112583_bib26","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.3390\/ijms21093175","article-title":"Fractalkine regulates hec-1a\/jeg-3 interaction by influencing the expression of implantation-related genes in an in vitro co-culture model","volume":"21","author":"Pap","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.yexcr.2021.112583_bib27","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3389\/fncel.2018.00365","article-title":"Role of the fractalkine receptor in CNS autoimmune inflammation: new approach utilizing a mouse model expressing the human CX3CR1I249\/M280 variant","volume":"12","author":"Cardona","year":"2018","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.yexcr.2021.112583_bib28","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s10571-019-00694-4","article-title":"Fractalkine induces hepcidin expression of BV-2 microglia and causes iron accumulation in SH-SY5Y cells, cell","volume":"39","author":"Pandur","year":"2019","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.yexcr.2021.112583_bib29","doi-asserted-by":"crossref","first-page":"480941","DOI":"10.1155\/2014\/480941","article-title":"Role of fractalkine\/CX3CL1 and its receptor in the pathogenesis of inflammatory and malignant diseases with emphasis on B cell malignancies","volume":"2014","author":"Ferretti","year":"2014","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.yexcr.2021.112583_bib30","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1097\/01.AOG.0000238333.37423.ab","article-title":"Iron intake and risk of ovulatory infertility","volume":"108","author":"Chavarro","year":"2006","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.yexcr.2021.112583_bib31","doi-asserted-by":"crossref","DOI":"10.4137\/CMWH.S8780","article-title":"Correlation between iron status parameters and hormone levels in women with polycystic ovary syndrome","volume":"5","author":"Al-Hakeim","year":"2012","journal-title":"Clin. Med. Insights Women's Health"},{"key":"10.1016\/j.yexcr.2021.112583_bib32","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1093\/molehr\/gan033","article-title":"Potential involvement of iron in the pathogenesis of peritoneal endometriosis","volume":"14","author":"Defr\u00e8re","year":"2008","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib33","doi-asserted-by":"crossref","first-page":"2810","DOI":"10.1093\/humrep\/del261","article-title":"Iron overload enhances epithelial cell proliferation in endometriotic lesions induced in a murine model","volume":"21","author":"Defr\u00e8re","year":"2006","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib34","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1477-7827-2-58","article-title":"Endometrial glands as a source of nutrients, growth factors and cytokines during the first trimester of human pregnancy: a morphological and immunohistochemical study","volume":"2","author":"Hempstock","year":"2004","journal-title":"Reprod. Biol. Endocrinol."},{"key":"10.1016\/j.yexcr.2021.112583_bib35","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1159\/000355112","article-title":"Severe iron deficiency is associated with a reduced conception rate in female rats","volume":"77","author":"Li","year":"2014","journal-title":"Gynecol. Obstet. Invest."},{"key":"10.1016\/j.yexcr.2021.112583_bib36","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.fertnstert.2016.04.002","article-title":"Endometrial expression and in vitro modulation of the iron transporter divalent metal transporter-1: implications for endometriosis","volume":"106","author":"Alvarado-D\u00edaz","year":"2016","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.yexcr.2021.112583_bib37","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1172\/JCI127341","article-title":"Effects of maternal iron status on placental and fetal iron homeostasis","volume":"130","author":"Sangkhae","year":"2020","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.yexcr.2021.112583_bib38","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1107\/S1399004715013073","article-title":"Iron binding to human heavy-chain ferritin","volume":"71","author":"Pozzi","year":"2015","journal-title":"Acta Crystallogr. Sect. D Biol. Crystallogr."},{"key":"10.1016\/j.yexcr.2021.112583_bib39","doi-asserted-by":"crossref","first-page":"1559S","DOI":"10.3945\/ajcn.117.155804","article-title":"Current understanding of iron homeostasis","volume":"106","author":"Anderson","year":"2017","journal-title":"Am. J. Clin. Nutr."},{"key":"10.1016\/j.yexcr.2021.112583_bib40","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.cmet.2005.01.003","article-title":"The iron exporter ferroportin\/Slc40a1 is essential for iron homeostasis","volume":"1","author":"Donovan","year":"2005","journal-title":"Cell Metabol."},{"key":"10.1016\/j.yexcr.2021.112583_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep33811","article-title":"Compartmentalized gene expression profiling of receptive endometrium reveals progesterone regulated ENPP3 is differentially expressed and secreted in glycosylated form","volume":"6","author":"Boggavarapu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.yexcr.2021.112583_bib42","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.abb.2011.02.001","article-title":"Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin 1 mRNA suppression in macrophages","volume":"508","author":"Harada","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.yexcr.2021.112583_bib43","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1089\/ars.2017.7176","article-title":"The roles of NRF2 in modulating cellular iron homeostasis","volume":"29","author":"Kerins","year":"2018","journal-title":"Antioxidants Redox Signal."},{"key":"10.1016\/j.yexcr.2021.112583_bib44","author":"ImageJ"},{"key":"10.1016\/j.yexcr.2021.112583_bib45","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.ab.2004.03.049","article-title":"Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells","volume":"331","author":"Riemer","year":"2004","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.yexcr.2021.112583_bib46","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0015-0282(16)58140-0","article-title":"Endometrial progesterone receptors and markers of uterine receptivity in the window of implantation","volume":"65","author":"Lessey","year":"1996","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.yexcr.2021.112583_bib47","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007787","article-title":"FOXO1 regulates uterine epithelial integrity and progesterone receptor expression critical for embryo implantation","volume":"14","author":"Vasquez","year":"2018","journal-title":"PLoS Genet."},{"key":"10.1016\/j.yexcr.2021.112583_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-51751-3","article-title":"Uterine SOX17: a key player in human endometrial receptivity and embryo implantation","volume":"9","author":"Kinnear","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.yexcr.2021.112583_bib49","first-page":"7673","article-title":"Correlation of NRF2 and progesterone receptor and its effects on ovarian cancer biology","volume":"11","author":"Czogalla","year":"2019","journal-title":"Canc. Manag. Res."},{"key":"10.1016\/j.yexcr.2021.112583_bib50","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1093\/oxfordjournals.humrep.a135793","article-title":"Progressive rise in the expression of interleukin-6 in human endometrium during menstrual cycle is initiated during the implantation window","volume":"10","author":"Tabibzadeh","year":"1995","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jri.2015.03.006","article-title":"Expression and localization of interleukin 1 beta and interleukin 1 receptor (type I) in the bovine endometrium and embryo","volume":"110","author":"Correia-\u00c1lvarez","year":"2015","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib52","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1034\/j.1600-0897.2002.01151.x","article-title":"Regulation of trophoblast invasion by IL-1\u03b2 and TGF-\u03b21","volume":"48","author":"Karmakar","year":"2002","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib53","first-page":"5130","article-title":"Correlation of il-1 and hb-egf with endometrial receptivity","volume":"16","author":"Wang","year":"2018","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.yexcr.2021.112583_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/aji.12173","article-title":"Interdisciplinary collaborative team for blastocyst implantation research: inception and perspectives","volume":"71","author":"Yoshinaga","year":"2014","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib55","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.molmed.2020.02.004","article-title":"Haptoglobin therapeutics and compartmentalization of cell-free hemoglobin toxicity","volume":"26","author":"Buehler","year":"2020","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.yexcr.2021.112583_bib56","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/molehr\/7.8.747","article-title":"Haptoglobin is present in human endometrium and shows elevated levels in the decidua during pregnancy","volume":"7","author":"Berkova","year":"2001","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib57","first-page":"e3257","article-title":"Bilaminar co-culture of primary rat cortical neurons and glia","volume":"57","author":"Shimizu","year":"2011","journal-title":"JoVE"},{"key":"10.1016\/j.yexcr.2021.112583_bib58","doi-asserted-by":"crossref","first-page":"803930","DOI":"10.1155\/2012\/803930","article-title":"A modified technique for culturing primary fetal rat cortical neurons","volume":"2012","author":"Xu","year":"2012","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.yexcr.2021.112583_bib59","doi-asserted-by":"crossref","first-page":"10563","DOI":"10.1074\/jbc.M109.035477","article-title":"Interactions between Chemokines: regulation of fractalkine\/CX 3CL1 homeostasis by SDF\/CXCL12 in cortical neurons","volume":"285","author":"Cook","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexcr.2021.112583_bib60","doi-asserted-by":"crossref","first-page":"844","DOI":"10.2174\/1389203720666190305165722","article-title":"Crosstalk between the CX3CL1\/CX3CR1 Axis and inflammatory signaling pathways in tissue injury","volume":"20","author":"Zhuang","year":"2019","journal-title":"Curr. Protein Pept. Sci."},{"key":"10.1016\/j.yexcr.2021.112583_bib61","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1095\/biolreprod.107.066480","article-title":"CX3CL1 and CCL14 regulate extracellular matrix and adhesion molecules in the trophoblast: potential roles in human embryo implantation","volume":"79","author":"Hannan","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib62","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/aji.12557","article-title":"Fractalkine\/CX3CR1 is involved in the pathogenesis of endometriosis by regulating endometrial stromal cell proliferation and invasion","volume":"76","author":"Hou","year":"2016","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib63","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0165-0378(98)00019-9","article-title":"The hormonal control of endometrial receptivity: estrogen (E2) and progesterone","volume":"39","author":"De Ziegler","year":"1998","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.yexcr.2021.112583_bib64","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1038\/s41598-017-18643-w","article-title":"The high concentration of progesterone is harmful for endometrial receptivity and decidualization","volume":"8","author":"Liang","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.yexcr.2021.112583_bib65","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.mce.2011.09.017","article-title":"Role of phosphorylation in progesterone receptor signaling and specificity","volume":"357","author":"Hagan","year":"2012","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.yexcr.2021.112583_bib66","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.redox.2012.10.001","article-title":"The Keap-1-Nrf2 pathway: mechanisms of activation and dysregulation in cancer","volume":"1","author":"Kansanen","year":"2013","journal-title":"Redox Biol"},{"key":"10.1016\/j.yexcr.2021.112583_bib67","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.freeradbiomed.2013.02.008","article-title":"Regulation of Nrf2 - an update","volume":"66","author":"Niture","year":"2014","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.yexcr.2021.112583_bib68","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1042\/BST20150014","article-title":"Dissecting molecular cross-talk between Nrf2 and NF-\u03baB response pathways","volume":"43","author":"Wardyn","year":"2015","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.yexcr.2021.112583_bib69","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1159\/000101737","article-title":"Uterine receptivity and cytokines: new concepts and new applications","volume":"64","author":"L\u00e9d\u00e9e","year":"2007","journal-title":"Gynecol. Obstet. Invest."},{"key":"10.1016\/j.yexcr.2021.112583_bib70","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.cellsig.2010.06.004","article-title":"Suppression of NF-\u03baB signaling by KEAP-1 regulation of IKK\u03b2 activity through autophagic degradation and inhibition of phosphorylation","volume":"22","author":"Kim","year":"2010","journal-title":"Cell. Signal."},{"key":"10.1016\/j.yexcr.2021.112583_bib71","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1095\/biolreprod.109.077800","article-title":"Models for study of human embryo implantation: choice of cell lines?","volume":"82","author":"Hannan","year":"2010","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib72","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1306.001","article-title":"Iron metabolism and the IRE\/IRP regulatory system: an update","volume":"1012","author":"Pantopoulos","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.yexcr.2021.112583_bib73","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.yjmcc.2008.09.714","article-title":"Downregulation of ferritin heavy chain increases labile iron pool, oxidative stress and cell death in cardiomyocytes","volume":"46","author":"Omiya","year":"2009","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.yexcr.2021.112583_bib74","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/humrep\/dem430","article-title":"Haemoglobin expression in human endometrium","volume":"23","author":"Dassen","year":"2008","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.yexcr.2021.112583_bib75","doi-asserted-by":"crossref","first-page":"148","DOI":"10.2337\/diaclin.34.3.148","article-title":"Role of haptoglobin in health and disease: a focus on diabetes","volume":"34","author":"MacKellar","year":"2016","journal-title":"Clin. Diabetes"},{"key":"10.1016\/j.yexcr.2021.112583_bib76","doi-asserted-by":"crossref","first-page":"523652","DOI":"10.1155\/2013\/523652","article-title":"The haptoglobin-cd163-heme oxygenase-1 pathway for hemoglobin scavenging","volume":"2013","author":"Thomsen","year":"2013","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.yexcr.2021.112583_bib77","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1530\/REP-18-0450","article-title":"Trophoblast-derived hyaluronan promotes the regulatory phenotype of decidual macrophages","volume":"157","author":"Wang","year":"2019","journal-title":"Reproduction"}],"container-title":["Experimental Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482721001154?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482721001154?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:18:07Z","timestamp":1762147087000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014482721001154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":77,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S0014482721001154"],"URL":"https:\/\/doi.org\/10.1016\/j.yexcr.2021.112583","relation":{},"ISSN":["0014-4827"],"issn-type":[{"value":"0014-4827","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fractalkine enhances endometrial receptivity and activates iron transport towards trophoblast cells in an in vitro co-culture system of HEC-1A and JEG-3\u00a0cells","name":"articletitle","label":"Article Title"},{"value":"Experimental Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yexcr.2021.112583","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"112583"}}