{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:58:00Z","timestamp":1793051880035,"version":"4.5.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"publisher","award":["202240214"],"award-info":[{"award-number":["202240214"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Cell Research"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.yexcr.2023.113649","type":"journal-article","created":{"date-parts":[[2023,5,22]],"date-time":"2023-05-22T01:51:48Z","timestamp":1684720308000},"page":"113649","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["SPARC-YAP\/TAZ inhibition prevents the fibroblasts-myofibroblasts transformation"],"prefix":"10.1016","volume":"429","author":[{"given":"Jingxiao","family":"Du","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianwei","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenkai","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoyang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingfa","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0122-2070","authenticated-orcid":false,"given":"Zhihua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/IIO.0000000000000231","article-title":"Trabeculectomy: a brief history and Review of current trends","volume":"58","author":"Koike","year":"2018","journal-title":"Int. Ophthalmol. Clin."},{"issue":"5","key":"10.1016\/j.yexcr.2023.113649_bib2","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.ajo.2009.06.018","article-title":"Three-year follow-up of the tube versus trabeculectomy study","volume":"148","author":"Gedde","year":"2009","journal-title":"Am. J. Ophthalmol."},{"key":"10.1016\/j.yexcr.2023.113649_bib3","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.exer.2015.03.021","article-title":"Conjunctival fibrosis following filtering glaucoma surgery","volume":"142","author":"Schlunck","year":"2016","journal-title":"Exp. Eye Res."},{"issue":"5","key":"10.1016\/j.yexcr.2023.113649_bib4","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1038\/nrm809","article-title":"Myofibroblasts and mechano-regulation of connective tissue remodelling","volume":"3","author":"Tomasek","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.yexcr.2023.113649_bib5","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.exer.2017.09.004","article-title":"5-Aza-2'-deoxycytidine induces human Tenon's capsule fibroblasts differentiation and fibrosis by up-regulating TGF-beta type I receptor","volume":"165","author":"Fu","year":"2017","journal-title":"Exp. Eye Res."},{"key":"10.1016\/j.yexcr.2023.113649_bib6","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/7982051","article-title":"Suppression of human Tenon fibroblast cell proliferation by lentivirus-mediated VEGF small hairpin RNA","volume":"2017","author":"Li","year":"2017","journal-title":"J Ophthalmol"},{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib7","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/02713683.2020.1805470","article-title":"The expression and role of hypoxia-induced factor-1\u03b1 in human Tenon's capsule fibroblasts under hypoxia","volume":"46","author":"Qin","year":"2021","journal-title":"Curr. Eye Res."},{"issue":"10","key":"10.1016\/j.yexcr.2023.113649_bib8","doi-asserted-by":"crossref","first-page":"1822","DOI":"10.1016\/j.ophtha.2007.03.050","article-title":"A phase III study of subconjunctival human anti-transforming growth factor beta(2) monoclonal antibody (CAT-152) to prevent scarring after first-time trabeculectomy","volume":"114","author":"Khaw","year":"2007","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.yexcr.2023.113649_bib9","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1080\/02713683.2018.1449222","article-title":"Matricellular proteins play a potential role in acute primary angle closure","volume":"43","author":"Wang","year":"2018","journal-title":"Curr. Eye Res."},{"issue":"10","key":"10.1016\/j.yexcr.2023.113649_bib10","doi-asserted-by":"crossref","first-page":"3906","DOI":"10.1167\/iovs.18-24534","article-title":"Matricellular protein levels in aqueous humor and surgical outcomes of trabeculectomy","volume":"59","author":"Zhang","year":"2018","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"7","key":"10.1016\/j.yexcr.2023.113649_bib11","doi-asserted-by":"crossref","first-page":"4084","DOI":"10.1167\/iovs.13-12463","article-title":"TGF-\u03b22-mediated ocular hypertension is attenuated in SPARC-null mice","volume":"55","author":"Swaminathan","year":"2014","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"1","key":"10.1016\/j.yexcr.2023.113649_bib12","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1006\/exer.2000.0853","article-title":"Expression and characterization of SPARC in human lens and in the aqueous and vitreous humors","volume":"71","author":"Yan","year":"2000","journal-title":"Exp. Eye Res."},{"issue":"1","key":"10.1016\/j.yexcr.2023.113649_bib13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/bph.13653","article-title":"The SPARC protein: an overview of its role in lung cancer and pulmonary fibrosis and its potential role in chronic airways disease","volume":"174","author":"Wong","year":"2017","journal-title":"Br. J. Pharmacol."},{"issue":"9","key":"10.1016\/j.yexcr.2023.113649_bib14","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1093\/rheumatology\/kez583","article-title":"Extracellular SPARC cooperates with TGF-\u03b2 signalling to induce pro-fibrotic activation of systemic sclerosis patient dermal fibroblasts","volume":"59","author":"Carvalheiro","year":"2020","journal-title":"Rheumatology"},{"key":"10.1016\/j.yexcr.2023.113649_bib15","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.biomaterials.2018.11.023","article-title":"Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness","volume":"192","author":"Tanaka","year":"2019","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.yexcr.2023.113649_bib16","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1038\/s41467-020-20851-4","article-title":"Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries","volume":"12","author":"Gharahkhani","year":"2021","journal-title":"Nat. Commun."},{"issue":"4","key":"10.1016\/j.yexcr.2023.113649_bib17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41580-018-0086-y","article-title":"Hippo-YAP\/TAZ signalling in organ regeneration and regenerative medicine","volume":"20","author":"Moya","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.yexcr.2023.113649_bib18","doi-asserted-by":"crossref","first-page":"46","DOI":"10.15252\/emmm.201506089","article-title":"Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2","volume":"9","author":"Loforese","year":"2017","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.yexcr.2023.113649_bib19","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.canlet.2019.07.015","article-title":"YAP1-mediated pancreatic stellate cell activation inhibits pancreatic cancer cell proliferation","volume":"462","author":"Xiao","year":"2019","journal-title":"Cancer Lett."},{"issue":"6","key":"10.1016\/j.yexcr.2023.113649_bib20","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1167\/iovs.61.6.30","article-title":"Wnt activation after inhibition restores trabecular meshwork cells tow ard a normal phenotype","volume":"61","author":"Dhamodaran","year":"2020","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"2","key":"10.1016\/j.yexcr.2023.113649_bib21","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s10561-012-9325-1","article-title":"A standardized laboratory and surgical method for in vitro culture isolation and expansion of primary human Tenon's fibroblasts","volume":"14","author":"De Falco","year":"2013","journal-title":"Cell Tissue Bank."},{"issue":"8","key":"10.1016\/j.yexcr.2023.113649_bib22","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1167\/tvst.10.8.7","article-title":"Effect of vitamin D3 on regulating human Tenon's fibroblasts activity","volume":"10","author":"Jia","year":"2021","journal-title":"Transl Vis Sci Technol"},{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib23","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1161\/CIRCRESAHA.120.316958","article-title":"Myofibroblasts and fibrosis: mitochondrial and metabolic control of cellular differentiation","volume":"127","author":"Gibb","year":"2020","journal-title":"Circ. Res."},{"issue":"4","key":"10.1016\/j.yexcr.2023.113649_bib24","doi-asserted-by":"crossref","first-page":"L344","DOI":"10.1152\/ajplung.00300.2014","article-title":"Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis","volume":"308","author":"Liu","year":"2015","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib25","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.yexcr.2023.113649_bib26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000458483","article-title":"Enhanced trabeculectomy: the moorfields safer surgery system","volume":"59","author":"Khaw","year":"2017","journal-title":"Dev. Ophthalmol."},{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib27","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.ophtha.2019.10.002","article-title":"Treatment outcomes in the primary tube versus trabeculectomy study after 3 Years of follow-up","volume":"127","author":"Gedde","year":"2020","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.yexcr.2023.113649_bib28","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0039-6257(77)90088-1","article-title":"The effect of intraocular pressure on resistance to outflow","volume":"22","author":"Moses","year":"1977","journal-title":"Surv. Ophthalmol."},{"issue":"1","key":"10.1016\/j.yexcr.2023.113649_bib29","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.preteyeres.2005.05.001","article-title":"Thrombospondin 1, thrombospondin 2 and the eye","volume":"25","author":"Hiscott","year":"2006","journal-title":"Prog. Retin. Eye Res."},{"issue":"1","key":"10.1016\/j.yexcr.2023.113649_bib30","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.yexcr.2004.02.024","article-title":"Overexpression of myocilin in cultured human trabecular meshwork cells","volume":"297","author":"Wentz-Hunter","year":"2004","journal-title":"Exp. Cell Res."},{"issue":"4","key":"10.1016\/j.yexcr.2023.113649_bib31","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.exer.2008.11.032","article-title":"Matricellular proteins in the trabecular meshwork","volume":"88","author":"Rhee","year":"2009","journal-title":"Exp. Eye Res."},{"issue":"8","key":"10.1016\/j.yexcr.2023.113649_bib32","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S0945-053X(00)00133-5","article-title":"SPARC, a matricellular protein: at the crossroads of cell-matrix communication","volume":"19","author":"Brekken","year":"2001","journal-title":"Matrix Biol."},{"key":"10.1016\/j.yexcr.2023.113649_bib33","article-title":"The role of SPARC (secreted protein acidic and rich in cysteine) in the pathogenesis of obesity, type 2 diabetes, and non-alcoholic fatty liver disease","author":"Atorrasagasti","year":"2022","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.yexcr.2023.113649_bib34","doi-asserted-by":"crossref","first-page":"146","DOI":"10.2174\/1874312901206010146","article-title":"The function of SPARC as a mediator of fibrosis","volume":"6","author":"Trombetta-Esilva","year":"2012","journal-title":"Open Rheumatol. J."},{"key":"10.1016\/j.yexcr.2023.113649_bib35","first-page":"76","article-title":"Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells","volume":"15","author":"Kirwan","year":"2009","journal-title":"Mol. Vis."},{"key":"10.1016\/j.yexcr.2023.113649_bib36","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.preteyeres.2017.02.001","article-title":"Characterizing the \"POAGome\": a bioinformatics-driven approach to primary open-angle glaucoma","volume":"58","author":"Danford","year":"2017","journal-title":"Prog. Retin. Eye Res."},{"issue":"6","key":"10.1016\/j.yexcr.2023.113649_bib37","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1167\/iovs.63.6.8","article-title":"Effect of SPARC suppression in mice, perfused human anterior segments, and trabecular meshwork cells","volume":"63","author":"MacDonald","year":"2022","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.yexcr.2023.113649_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2021.109049","article-title":"SPARC knockdown attenuated TGF-beta1-induced fibrotic effects through Smad2\/3 pathways in human pterygium fibroblasts","volume":"713","author":"Fan","year":"2021","journal-title":"Arch. Biochem. Biophys."},{"issue":"5","key":"10.1016\/j.yexcr.2023.113649_bib39","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1167\/iovs.12-11362","article-title":"Overexpression of SPARC in human trabecular meshwork increases intraocular pressure and alters extracellular matrix","volume":"54","author":"Oh","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib40","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0039-6257(87)90091-9","article-title":"2nd: wound healing in glaucoma filtering surgery","volume":"32","author":"Skuta","year":"1987","journal-title":"Surv. Ophthalmol."},{"issue":"2","key":"10.1016\/j.yexcr.2023.113649_bib41","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s004170000241","article-title":"Transforming growth factor-beta 2 levels in aqueous humor of glaucomatous eyes","volume":"239","author":"Inatani","year":"2001","journal-title":"Graefes Arch. Clin. Exp. Ophthalmol."},{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib42","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0021-5155(01)00523-8","article-title":"Higher concentration of transforming growth factor-beta in aqueous humor of glaucomatous eyes and diabetic eyes","volume":"46","author":"Ochiai","year":"2002","journal-title":"Jpn. J. Ophthalmol."},{"issue":"14","key":"10.1016\/j.yexcr.2023.113649_bib43","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1167\/iovs.19-27091","article-title":"Coral K: lowered decorin with aberrant extracellular matrix remodeling in aqueous humor and Tenon's tissue from primary glaucoma patients","volume":"60","author":"NikhalaShree","year":"2019","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"1","key":"10.1016\/j.yexcr.2023.113649_bib44","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.exer.2004.08.018","article-title":"Comparative effects of TGF-beta 1 and TGF-beta 2 on extracellular matrix production, proliferation, migration, and collagen contraction of human Tenon's capsule fibroblasts in pseudoexfoliation and primary open-angle glaucoma","volume":"80","author":"Kottler","year":"2005","journal-title":"Exp. Eye Res."},{"issue":"6","key":"10.1016\/j.yexcr.2023.113649_bib45","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1111\/j.1582-4934.2011.01400.x","article-title":"In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon's fibroblasts: comparisons with mitomycin C","volume":"16","author":"Seet","year":"2012","journal-title":"J. Cell Mol. Med."},{"issue":"4","key":"10.1016\/j.yexcr.2023.113649_bib46","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1167\/iovs.12-11474","article-title":"Regulation of SPARC by transforming growth factor beta2 in human trabecular meshwork","volume":"54","author":"Kang","year":"2013","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.yexcr.2023.113649_bib47","first-page":"177","article-title":"SPARC is expressed in scars of the Tenon's capsule and mediates scarring properties of human Tenon's fibroblasts in vitro","volume":"17","author":"Fuchshofer","year":"2011","journal-title":"Mol. Vis."},{"key":"10.1016\/j.yexcr.2023.113649_bib48","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/5703286","article-title":"SPARC levels modulate the capacity of mitomycin to inhibit the proliferation of human Tenon's capsule fibroblasts","volume":"2020","author":"Guo","year":"2020","journal-title":"J Ophthalmol"},{"issue":"4","key":"10.1016\/j.yexcr.2023.113649_bib49","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1165\/rcmb.2021-0463OC","article-title":"Overexpression of decay accelerating factor mitigates fibrotic responses to lung injury","volume":"67","author":"Vittal","year":"2022","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.yexcr.2023.113649_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2022.120905","article-title":"C3aR contributes to unilateral ureteral obstruction-induced renal interstitial fibrosis via the activation of the NLRP3 inflammasome","volume":"308","author":"You","year":"2022","journal-title":"Life Sci."},{"key":"10.1016\/j.yexcr.2023.113649_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115496","article-title":"Potential shared therapeutic and hepatotoxic mechanisms of Tripterygium wilfordii polyglycosides treating three kinds of autoimmune skin diseases by regulating IL-17 signaling pathway and Th17 cell differentiation","volume":"296","author":"Chen","year":"2022","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.yexcr.2023.113649_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128178","article-title":"Interleukin 17A deficiency alleviates fluoride-induced testicular injury by inhibiting the immune response and apoptosis","volume":"263","author":"Li","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.yexcr.2023.113649_bib53","article-title":"A comprehensive network map of IL-17A signaling pathway","author":"Rex","year":"2022","journal-title":"J Cell Commun Signal"},{"issue":"2","key":"10.1016\/j.yexcr.2023.113649_bib54","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1096\/fj.201600840R","article-title":"A small-molecule inhibitor of NF-kappaB-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury","volume":"31","author":"Ren","year":"2017","journal-title":"Faseb. J."},{"issue":"6","key":"10.1016\/j.yexcr.2023.113649_bib55","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1002\/hep.27348","article-title":"Mouse hepatocyte overexpression of NF-kappaB-inducing kinase (NIK) triggers fatal macrophage-dependent liver injury and fibrosis","volume":"60","author":"Shen","year":"2014","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.yexcr.2023.113649_bib56","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.devcel.2019.06.003","article-title":"The Hippo signaling pathway in development and disease","volume":"50","author":"Zheng","year":"2019","journal-title":"Dev. Cell"},{"issue":"4","key":"10.1016\/j.yexcr.2023.113649_bib57","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/nrc3458","article-title":"The Hippo pathway and human cancer","volume":"13","author":"Harvey","year":"2013","journal-title":"Nat. Rev. Cancer"},{"issue":"21","key":"10.1016\/j.yexcr.2023.113649_bib58","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1101\/gad.1602907","article-title":"Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control","volume":"21","author":"Zhao","year":"2007","journal-title":"Genes Dev."},{"issue":"8","key":"10.1016\/j.yexcr.2023.113649_bib59","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1177\/0022034519851804","article-title":"YAP-induced endothelial-mesenchymal transition in oral submucous fibrosis","volume":"98","author":"Li","year":"2019","journal-title":"J. Dent. Res."},{"issue":"5","key":"10.1016\/j.yexcr.2023.113649_bib60","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1002\/hep.30928","article-title":"Hepatocyte stress increases expression of yes-associated protein and transcriptional coactivator with PDZ-binding motif in hepatocytes to promote parenchymal inflammation and fibrosis","volume":"71","author":"Mooring","year":"2020","journal-title":"Hepatology"},{"key":"10.1016\/j.yexcr.2023.113649_bib61","first-page":"129","article-title":"Ocular phenotypic consequences of a single copy deletion of the Yap1 gene (Yap1 (+\/-)) in mice","volume":"25","author":"Kim","year":"2019","journal-title":"Mol. Vis."},{"key":"10.1016\/j.yexcr.2023.113649_bib62","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2021.728932","article-title":"RhoA\/ROCK-YAP\/TAZ Axis regulates the fibrotic activity in dexamethasone-treated human trabecular meshwork cells","volume":"8","author":"Liu","year":"2021","journal-title":"Front. Mol. Biosci."},{"issue":"10","key":"10.1016\/j.yexcr.2023.113649_bib63","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1167\/iovs.61.10.41","article-title":"Crosslinked extracellular matrix stiffens human trabecular meshwork cells via dysregulating beta-catenin and YAP\/TAZ signaling pathways","volume":"61","author":"Yemanyi","year":"2020","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"issue":"5","key":"10.1016\/j.yexcr.2023.113649_bib64","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1681\/ASN.2019101052","article-title":"Tubule-specific mst1\/2 deficiency induces CKD via YAP and non-YAP mechanisms","volume":"31","author":"Xu","year":"2020","journal-title":"J. Am. Soc. Nephrol."},{"issue":"7","key":"10.1016\/j.yexcr.2023.113649_bib65","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/ncb2070","article-title":"The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing","volume":"12","author":"Jun","year":"2010","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.yexcr.2023.113649_bib66","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/978-1-4939-6430-7_34","article-title":"CCN2 in skin fibrosis","volume":"1489","author":"Leask","year":"2017","journal-title":"Methods Mol. Biol."}],"container-title":["Experimental Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482723001969?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482723001969?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T04:46:03Z","timestamp":1757997963000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014482723001969"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":66,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["S0014482723001969"],"URL":"https:\/\/doi.org\/10.1016\/j.yexcr.2023.113649","relation":{},"ISSN":["0014-4827"],"issn-type":[{"value":"0014-4827","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SPARC-YAP\/TAZ inhibition prevents the fibroblasts-myofibroblasts transformation","name":"articletitle","label":"Article Title"},{"value":"Experimental Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yexcr.2023.113649","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"113649"}}