{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:21:01Z","timestamp":1792038061812,"version":"4.4.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental and Molecular Pathology"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.yexmp.2004.08.012","type":"journal-article","created":{"date-parts":[[2004,12,16]],"date-time":"2004-12-16T05:02:41Z","timestamp":1103173361000},"page":"41-48","source":"Crossref","is-referenced-by-count":16,"title":["Pathological characterization of Kank in renal cell carcinoma"],"prefix":"10.1016","volume":"78","author":[{"given":"Badal","family":"Chandra Roy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teiichiro","family":"Aoyagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubhashish","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimie","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiichi","family":"Iwaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaaki","family":"Tachibana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryoiti","family":"Kiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yexmp.2004.08.012_bib1","first-page":"3941","article-title":"Two regions of deletion in 9p23\u201324 in sporadic breast cancer","volume":"59","author":"An","year":"1999","journal-title":"Cancer Res."},{"key":"10.1016\/j.yexmp.2004.08.012_bib2","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/j.1442-2042.1996.tb00560.x","article-title":"Gene expression of TGF-alpha, EGF and IL-6 in cultured renal tubular cells and renal cell carcinoma","volume":"3","author":"Aoyagi","year":"1996","journal-title":"Int. J. Urol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib3","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0002-9440(10)65120-6","article-title":"Evaluation of the clonal relationship between primary and metastatic renal cell carcinoma by comparative genomic hybridization","volume":"155","author":"Bissig","year":"1999","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib4","first-page":"224","article-title":"Localization of tumor suppressor loci on chromosome 9 in primary human renal cell carcinomas","volume":"55","author":"Cairns","year":"1995","journal-title":"Cancer Res."},{"key":"10.1016\/j.yexmp.2004.08.012_bib5","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0145-2126(03)00158-9","article-title":"Down-regulation of HP1 and up-regulation of negative regulators of JAK\/STAT signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral blood CD4+ T-cells","volume":"28","author":"Cheng","year":"2004","journal-title":"Leuk. Res."},{"key":"10.1016\/j.yexmp.2004.08.012_bib6","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.yexmp.2004.08.012_bib7","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/gcc.10266","article-title":"Classical Hodgkin lymphoma is associated with frequent gains of 17q","volume":"38","author":"Chui","year":"2003","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1016\/j.yexmp.2004.08.012_bib8","doi-asserted-by":"crossref","first-page":"6795","DOI":"10.1128\/MCB.18.11.6795","article-title":"Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation","volume":"18","author":"Danial","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib9","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s004390050205","article-title":"Characterization of double minute chromosomes' DNA content in a human high grade astrocytoma cell line by using comparative genomic hybridization and fluorescence in situ hybridization","volume":"98","author":"Giollant","year":"1996","journal-title":"Hum. Genet."},{"key":"10.1016\/j.yexmp.2004.08.012_bib10","first-page":"7731","article-title":"Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma: gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis","volume":"61","author":"Gunawan","year":"2001","journal-title":"Cancer Res."},{"key":"10.1016\/j.yexmp.2004.08.012_bib11","first-page":"6200","article-title":"Cytogenetic and morphologic typing of 58 papillary renal cell carcinomas: evidence for a cytogenetic evolution of type 2 from type 1 tumors","volume":"63","author":"Gunawan","year":"2003","journal-title":"Cancer Res."},{"key":"10.1016\/j.yexmp.2004.08.012_bib12","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/mc.1051","article-title":"A comprehensive analysis of loss of heterozygosity caused by hemizygous deletions in renal cell carcinoma using a subtraction library","volume":"31","author":"Hatano","year":"2001","journal-title":"Mol. Carcinog."},{"key":"10.1016\/j.yexmp.2004.08.012_bib13","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1046\/j.1365-2559.2002.01507.x","article-title":"Identifying BAC clones for diagnosis of conventional renal cell carcinoma by FISH","volume":"41","author":"Heinze","year":"2002","journal-title":"Histopathology"},{"key":"10.1016\/j.yexmp.2004.08.012_bib14","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/ijc.2910540507","article-title":"Deletions of the short arm of chromosome 9, including the interferon-alpha\/-beta genes, in acute lymphocytic leukemia. Studies on loss of heterozygosity, parental origin of deleted genes and prognosis","volume":"54","author":"Heyman","year":"1993","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.yexmp.2004.08.012_bib15","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1002\/ijc.10845","article-title":"Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2","volume":"103","author":"Joos","year":"2003","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.yexmp.2004.08.012_bib16","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.278.5341.1309","article-title":"A TEL\u2013JAK2 fusion protein with constitutive kinase activity in human leukemia","volume":"278","author":"Lacronique","year":"1997","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.yexmp.2004.08.012_bib17","doi-asserted-by":"crossref","first-page":"2369","DOI":"10.1182\/blood.V93.7.2369","article-title":"Constitutive activation of the JAK2\/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines","volume":"93","author":"Liu","year":"1999","journal-title":"Blood"},{"key":"10.1016\/j.yexmp.2004.08.012_bib18","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/375503a0","article-title":"Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16","volume":"375","author":"Lukas","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.yexmp.2004.08.012_bib19","first-page":"2491","article-title":"Multifocal renal cell carcinoma: evidence for a common clonal origin","volume":"4","author":"Miyake","year":"1998","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.yexmp.2004.08.012_bib20","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/dnares\/3.1.17","article-title":"Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161\u2013KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1","volume":"3","author":"Nagase","year":"1996","journal-title":"DNA Res."},{"key":"10.1016\/j.yexmp.2004.08.012_bib21","doi-asserted-by":"crossref","first-page":"601","DOI":"10.5858\/2003-127-0601-MMOCFC","article-title":"Molecular monitoring of cerebrospinal fluid can predict clinical relapse in acute lymphoblastic leukemia with eosinophilia","volume":"127","author":"Nunez","year":"2003","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.yexmp.2004.08.012_bib22","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1002\/(SICI)1098-2744(199807)22:3<158::AID-MC3>3.0.CO;2-H","article-title":"A whole-genome analysis of allelic changes in renal cell carcinoma by in-gel competitive reassociation","volume":"22","author":"Ohki","year":"1998","journal-title":"Mol. Carcinog."},{"key":"10.1016\/j.yexmp.2004.08.012_bib23","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1182\/blood.V90.7.2535","article-title":"Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia","volume":"90","author":"Peeters","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.yexmp.2004.08.012_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/gcc.1111","article-title":"Molecular cytogenetic characterization of early and late renal cell carcinomas in von Hippel\u2013Lindau disease","volume":"31","author":"Phillips","year":"2001","journal-title":"Genes Chromosomes Cancer"},{"key":"10.1016\/j.yexmp.2004.08.012_bib25","first-page":"13","article-title":"A differential genomic cloning for cancer study: an outline and applications","volume":"1","author":"Rodley","year":"2003","journal-title":"Recent Res. Devel. Mol. Biol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib26","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1016\/S0022-5347(05)65346-3","article-title":"Allelic loss on chromosomes 8 and 9 correlates with clinical outcome in locally advanced clear cell carcinoma of the kidney","volume":"167","author":"Presti","year":"2002","journal-title":"J. Urol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib27","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1097\/01.MP.0000086627.74271.13","article-title":"Allelic loss and tumor pathology in head and neck squamous cell carcinoma","volume":"16","author":"Rybicki","year":"2003","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib28","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S0002-9440(10)64260-5","article-title":"Unique patterns of allelic imbalance distinguish type 1 from type 2 sporadic papillary renal cell carcinoma","volume":"161","author":"Sanders","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib29","doi-asserted-by":"crossref","first-page":"36585","DOI":"10.1074\/jbc.M204244200","article-title":"A novel ankyrin repeat-containing gene (Kank) located at 9p24 is a growth suppressor of renal cell carcinoma","volume":"277","author":"Sarkar","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yexmp.2004.08.012_bib30","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1002\/(SICI)1096-9896(200003)190:4<457::AID-PATH551>3.0.CO;2-C","article-title":"Allelic loss at the D9S171 locus on chromosome 9p13 is associated with progression of papillary renal cell carcinoma","volume":"190","author":"Schraml","year":"2000","journal-title":"J. Pathol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib31","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/S0002-9440(10)64001-1","article-title":"CDKNA2A mutation analysis, protein expression, and deletion mapping of chromosome 9p in conventional clear-cell renal carcinomas: evidence for a second tumor suppressor gene proximal to CDKN2A","volume":"158","author":"Schraml","year":"2001","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib32","first-page":"817","article-title":"Deletion of chromosomes 9p and 17 associated with abnormal expression of p53, p16\/MTS1 and p15\/MTS2 gene protein in hepatocellular carcinomas","volume":"113","author":"Shao","year":"2000","journal-title":"Chin. Med. J. (Engl)"},{"key":"10.1016\/j.yexmp.2004.08.012_bib33","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1177\/39.6.1709656","article-title":"Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections","volume":"39","author":"Shi","year":"1991","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.yexmp.2004.08.012_bib34","first-page":"1025","article-title":"Patterns of chromosomal imbalances in muscle invasive bladder cancer","volume":"17","author":"Simon","year":"2000","journal-title":"Int. J. Oncol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib35","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1034\/j.1600-0609.2001.t01-1-00385.x","article-title":"Constitutive activation of STAT transcription factors in acute myelogenous leukemia","volume":"67","author":"Spiekermann","year":"2001","journal-title":"Eur. J. Haematol."},{"key":"10.1016\/j.yexmp.2004.08.012_bib36","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/(SICI)1098-2264(199710)20:2<208::AID-GCC13>3.0.CO;2-M","article-title":"Combined chromosome microdissection and comparative genomic hybridization detect multiple sites of amplification DNA in a human lung carcinoma cell line","volume":"20","author":"Taguchi","year":"1997","journal-title":"Genes Chromosomes Cancer"}],"container-title":["Experimental and Molecular Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014480004000899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014480004000899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T15:21:23Z","timestamp":1625152883000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014480004000899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0014480004000899"],"URL":"https:\/\/doi.org\/10.1016\/j.yexmp.2004.08.012","relation":{},"ISSN":["0014-4800"],"issn-type":[{"value":"0014-4800","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}