{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T05:52:19Z","timestamp":1768974739897,"version":"3.49.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental and Molecular Pathology"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.yexmp.2010.03.004","type":"journal-article","created":{"date-parts":[[2010,3,18]],"date-time":"2010-03-18T08:25:39Z","timestamp":1268900739000},"page":"380-387","source":"Crossref","is-referenced-by-count":19,"title":["The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats"],"prefix":"10.1016","volume":"88","author":[{"given":"F.","family":"Bardag-Gorce","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Oliva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.C.","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.A.","family":"French","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.W.","family":"French","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.yexmp.2010.03.004_bib1","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1002\/hep.22231","article-title":"S-Adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation","volume":"47","author":"Ara","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.yexmp.2010.03.004_bib2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1053\/gast.2002.34177","article-title":"The importance of cycling of blood alcohol levels in the pathogenesis of experimental alcoholic liver disease in rats","volume":"123","author":"Bardag-Gorce","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.yexmp.2010.03.004_bib3","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.yexmp.2006.10.006","article-title":"Histone acetyltransferase p300 modulates in an epigenetic manner at high blood alcohol levels","volume":"82","author":"Bardag-Gorce","year":"2007","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib4","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1111\/j.1530-0277.2008.00885.x","article-title":"Chronic ethanol feeding alters hepatocyte memory which is not altered by acute feeding","volume":"33","author":"Bardag-Gorce","year":"2009","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.yexmp.2010.03.004_bib5","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"issue":"4","key":"10.1016\/j.yexmp.2010.03.004_bib37","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1155\/2000\/801735","article-title":"Mechanisms of alcoholic liver injury","volume":"14","author":"French","year":"2000","journal-title":"Can. J. Gastroenterol."},{"issue":"11 Suppl","key":"10.1016\/j.yexmp.2010.03.004_bib6","first-page":"1585","article-title":"The pathogenesis and significance of the urinary alcoholic cycle in rats fed ethanol intragastrically","volume":"29","author":"French","year":"2005","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.yexmp.2010.03.004_bib7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.yexmp.2005.06.006","article-title":"Microarray analysis of gene expression of the liver during urinary ethanol cycle in rats fed ethanol intragastrically at a constant rate","volume":"79","author":"French","year":"2005","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib8","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1007\/s12072-008-9082-1","article-title":"Effects of S-adenosylmethionine on liver methionine metabolism and steatosis with ethanol-induced liver injury in rats","volume":"2","author":"Gong","year":"2008","journal-title":"Hepatol. Inst."},{"key":"10.1016\/j.yexmp.2010.03.004_bib9","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1002\/hep.21138","article-title":"Differential liver sensitization to Toll-like receptor pathways in mice with cirrhotic fatty liver","volume":"43","author":"Gustot","year":"2006","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.yexmp.2010.03.004_bib10","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.ccr.2007.05.005","article-title":"Chromatin modulation by oncogenic transcription factors: new complexity, new therapeutic targets","volume":"11","author":"Hormaeche","year":"2007","journal-title":"Cancer Cell"},{"key":"10.1016\/j.yexmp.2010.03.004_bib11","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1002\/hep.22470","article-title":"The critical role of Toll-like receptor (TLR)4 in alcoholic liver disease is independent of the common TLR ad adapter MyD88","volume":"48","author":"Hritz","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.yexmp.2010.03.004_bib12","first-page":"C14","article-title":"Changes in methionine adenosyltransferase during liver regeneration in the rat","volume":"225","author":"Huang","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib13","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1002\/hep.510290525","article-title":"Differential effect of thioacemide on hepatic methionine adenosyltransferase expression in the rat","volume":"29","author":"Huang","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.yexmp.2010.03.004_bib14","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/SHK.0b013e318160f417","article-title":"S-Adenosyl-l-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model","volume":"30","author":"Karaa","year":"2008","journal-title":"Shock"},{"issue":"Suppl 462A","key":"10.1016\/j.yexmp.2010.03.004_bib15","article-title":"Modification to the liver mitochondrial proteasome by chronic alcohol consumption and S-adenosylmethionine","volume":"48","author":"Kelley","year":"2008","journal-title":"Hepatology"},{"issue":"Suppl 635A","key":"10.1016\/j.yexmp.2010.03.004_bib16","article-title":"S-Adenosylmethionine attenuates chronic alcohol-induced mitochondrial dysfunction and hypoxia in liver","volume":"48","author":"King","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.yexmp.2010.03.004_bib17","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1038\/labinvest.2008.69","article-title":"Changes in S-adenosyl-methionine and GSH homeostasis during endotoxemia in mice","volume":"88","author":"Ko","year":"2008","journal-title":"Lab. Invest."},{"key":"10.1016\/j.yexmp.2010.03.004_bib18","doi-asserted-by":"crossref","first-page":"G118","DOI":"10.1152\/ajpgi.2000.279.1.G118","article-title":"Mechanism of the alcohol cycle pattern: role of the hypothalamic\u2013pituitary\u2013thyroid axis","volume":"279","author":"Li","year":"2000","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib19","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/exmp.2001.2381","article-title":"Thyroid hormone causes liver necrosis in rats fed ethanol intragastrically","volume":"76","author":"Li","year":"2001","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib20","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1016\/j.lfs.2004.05.032","article-title":"Catecholamines are involved in the mechanism of the urinary alcohol level cycle in rats fed ethanol intragastrically at a constant rate","volume":"75","author":"Li","year":"2004","journal-title":"Life Sci."},{"key":"10.1016\/j.yexmp.2010.03.004_bib21","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.yexmp.2004.12.001","article-title":"Uncoupling of oxidative phosphorylation prevents the urinary alcohol level cycling caused b feeding ethanol continuously at a constant rate","volume":"78","author":"Li","year":"2005","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib22","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.yexmp.2009.11.003","article-title":"The effect of propranolol on gene expression during blood alcohol cycle of rats fed ethanol intragastrically","volume":"88","author":"Li","year":"2010","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib23","article-title":"Gene expression modification in the liver caused by binge drinking and S-adenosylmethionine feeding. The role of epigenetic changes","author":"Li","year":"2009","journal-title":"Gene Nutr."},{"key":"10.1016\/j.yexmp.2010.03.004_bib24","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.yexmp.2004.08.005","article-title":"The effect of rotenone on the urinary ethanol cycle in rats fed ethanol intragastrically","volume":"77","author":"Li","year":"2004","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib25","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1096\/fj.01-0401rev","article-title":"S-adenosylmethionine: a control switch that regulates liver function","volume":"16","author":"Mato","year":"2002","journal-title":"FASEB J."},{"key":"10.1016\/j.yexmp.2010.03.004_bib26","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0741-8329(02)00224-0","article-title":"S-adenosylmethionine cytokines and alcohol liver disease","volume":"27","author":"McClain","year":"2002","journal-title":"Alcohol"},{"key":"10.1016\/j.yexmp.2010.03.004_bib27","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3748\/wjg.15.705","article-title":"Epigenetics of proteasome inhibition in the liver of rats fed ethanol chronically","volume":"15","author":"Oliva","year":"2009","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib28","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.yexmp.2008.11.002","article-title":"Betaine prevents Mallory\u2013Denk body formation in drug-primed mice by epigenetic mechanisms","volume":"86","author":"Oliva","year":"2009","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib29","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.lfs.2007.07.030","article-title":"Ethanol and chromatin remodeling histone H3, methylation of lys 4 and lys 9 correlates with up and down regulation of genes in rat hepatocytes","volume":"81","author":"Pal-Bhaara","year":"2007","journal-title":"Life Sci."},{"key":"10.1016\/j.yexmp.2010.03.004_bib30","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1111\/j.1530-0277.2008.00729.x","article-title":"Emerging role of epigenetics in the actions of alcohol","volume":"32","author":"Shukla","year":"2008","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.yexmp.2010.03.004_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1530-0277.2008.00803.x","article-title":"S-Adenosyl-methionine co-administration prevents the ethanol-elicited dissociation of hepatic mitochondrial ribosomes in male rats","volume":"33","author":"Sykora","year":"2009","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.yexmp.2010.03.004_bib32","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1111\/j.1440-1746.2009.05854.x","article-title":"Toll-like receptors and their role in gastrointestinal disease","volume":"24","author":"Testro","year":"2009","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.yexmp.2010.03.004_bib33","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1530-0277.1985.tb05046.x","article-title":"Cyclic pattern of blood alcohol levels during continuous intragastric ethanol infusion in rats","volume":"9","author":"Tsukamoto","year":"1985","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.yexmp.2010.03.004_bib34","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1002\/hep.1840170512","article-title":"Changes in type IV collagen content in livers of patients with alcoholic liver disease","volume":"17","author":"Tsutsumi","year":"1983","journal-title":"Hepatology"},{"key":"10.1016\/j.yexmp.2010.03.004_bib35","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/nature04431","article-title":"The polycomb group protein EZH2 directly controls DNA methylation","volume":"439","author":"Vire","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.yexmp.2010.03.004_bib36","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1152\/ajpgi.00406.2005","article-title":"Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E1476 cells","volume":"29s","author":"Wu","year":"2006","journal-title":"Am. J. Physiol. Gastrointest. Liver Phys."}],"container-title":["Experimental and Molecular Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014480010000456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014480010000456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,24]],"date-time":"2021-10-24T23:29:31Z","timestamp":1635118171000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014480010000456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S0014480010000456"],"URL":"https:\/\/doi.org\/10.1016\/j.yexmp.2010.03.004","relation":{},"ISSN":["0014-4800"],"issn-type":[{"value":"0014-4800","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]}}}