{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:32:05Z","timestamp":1790886725306,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81271769"],"award-info":[{"award-number":["81271769"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81872542"],"award-info":[{"award-number":["81872542"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006765","name":"Chinese Medical Association","doi-asserted-by":"publisher","award":["81271769"],"award-info":[{"award-number":["81271769"]}],"id":[{"id":"10.13039\/501100006765","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006765","name":"Chinese Medical Association","doi-asserted-by":"publisher","award":["81872542"],"award-info":[{"award-number":["81872542"]}],"id":[{"id":"10.13039\/501100006765","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental and Molecular Pathology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.yexmp.2020.104589","type":"journal-article","created":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T10:44:36Z","timestamp":1607165076000},"page":"104589","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["miRNA microarray profiling in patients with androgenic alopecia and the effects of miR-133b on hair growth"],"prefix":"10.1016","volume":"118","author":[{"given":"Wenjia","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaojian","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yexmp.2020.104589_bb0005","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1083\/jcb.201404001","article-title":"MicroRNA-214 controls skin and hair follicle development by modulating the activity of the Wnt pathway","volume":"207","author":"Ahmed","year":"2014","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0010","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1111\/exd.12785","article-title":"MicroRNAs (miRNAs) in the control of HF development and cycling: the next frontiers in hair research","volume":"24","author":"Andl","year":"2015","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0015","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.cub.2006.04.005","article-title":"The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles","volume":"16","author":"Andl","year":"2006","journal-title":"Curr. Biol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0020","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.3389\/fphar.2019.01528","article-title":"Dihydrotestosterone regulates hair growth through the Wnt\/b-catenin pathway in C57BL\/6 mice and in vitro organ culture","volume":"10","author":"Chen","year":"2020","journal-title":"Front. Pharmacol."},{"issue":"8","key":"10.1016\/j.yexmp.2020.104589_bb0025","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1016\/j.celrep.2019.10.062","article-title":"miR-29a\/b1 inhibits hair follicle stem cell lineage progression by spatiotemporally suppressing WNT and BMP signaling","volume":"29","author":"Ge","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.yexmp.2020.104589_bb0030","doi-asserted-by":"crossref","first-page":"135","DOI":"10.4110\/in.2011.11.3.135","article-title":"MicroRNAs in human diseases: from cancer to cardiovascular disease","volume":"11","author":"Ha","year":"2011","journal-title":"Immune Netw"},{"key":"10.1016\/j.yexmp.2020.104589_bb0035","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s12895-017-0054-9","article-title":"Expression profiling and bioinformatic analyses suggest new target genes and pathways for human hair follicle related microRNAs","volume":"17","author":"Hochfeld","year":"2017","journal-title":"BMC Dermatol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0040","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ijpharm.2017.08.073","article-title":"Peptide modified mesenchymal stem cells as targeting delivery system transfected with miR-133b for the treatment of cerebral ischemia","volume":"531","author":"Huang","year":"2017","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.yexmp.2020.104589_bb0045","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1111\/j.1365-2133.2005.06453.x","article-title":"Interferongamma is a potent inducer of catagen-like changes in cultured human anagen hair follicles","volume":"152","author":"Ito","year":"2005","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0050","doi-asserted-by":"crossref","first-page":"181","DOI":"10.5021\/ad.2013.25.2.181","article-title":"The annual changes of clinical manifestation of androgenetic alopecia clinic in korean males and females: a outpatient-based study","volume":"25","author":"Jang","year":"2013","journal-title":"Ann. Dermatol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0055","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1600-0625.2009.00939.x","article-title":"Methods in hair research: how to objectively distinguish between anagen and catagen in human hair follicle organ culture","volume":"19","author":"Kloepper","year":"2010","journal-title":"Exp. Dermatol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0060","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s00403-005-0619-z","article-title":"Human hair growth ex vivo is correlated with in vivo hair growth: selective categorization of hair follicles for more reliable hair follicle organ culture","volume":"297","author":"Kwon","year":"2006","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.yexmp.2020.104589_bb0065","doi-asserted-by":"crossref","first-page":"243","DOI":"10.5021\/ad.2012.24.3.243","article-title":"Characteristics of androgenetic alopecia in asian","volume":"24","author":"Lee","year":"2012","journal-title":"Ann. Dermatol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0070","doi-asserted-by":"crossref","first-page":"50193","DOI":"10.18632\/oncotarget.16745","article-title":"miR-133b, a particular member of myomiRs, coming into playing its unique pathological role in human cancer","volume":"8","author":"Li","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.yexmp.2020.104589_bb0075","doi-asserted-by":"crossref","first-page":"3869","DOI":"10.1096\/fj.10-160663","article-title":"Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle","volume":"24","author":"Mardaryev","year":"2010","journal-title":"FASEB J."},{"key":"10.1016\/j.yexmp.2020.104589_bb0080","first-page":"804","article-title":"A random study of Asian male androgenetic alopecia in Bangkok","volume":"28","author":"Pathomvanich","year":"2002","journal-title":"Thailand. Dermatologic Surgery"},{"key":"10.1016\/j.yexmp.2020.104589_bb0085","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1046\/j.0022-202X.2004.22224.x","article-title":"Wnt signaling through the beta-catenin pathway is sufficient to maintain, but not restore, anagen-phase characteristics of dermal papilla cells","volume":"122","author":"Shimizu","year":"2004","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.yexmp.2020.104589_bb0090","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.4065\/80.10.1316","article-title":"Psychological effect, pathophysiology, and management of androgenetic alopecia in men","volume":"80","author":"Stough","year":"2005","journal-title":"Mayo Clin. Proc."},{"issue":"1","key":"10.1016\/j.yexmp.2020.104589_bb0095","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/jmcb\/mjy032","article-title":"\u03b2-Catenin activation in hair follicle dermal stem cells induces ectopic hair outgrowth and skin fibrosis","volume":"11","author":"Tao","year":"2019","journal-title":"J. Mol. Cell Biol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0100","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.yexcr.2016.03.027","article-title":"MicroRNA-133b inhibits hepatocellular carcinoma cell progression by targeting Sirt1","volume":"343","author":"Tian","year":"2016","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.yexmp.2020.104589_bb0105","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1111\/j.1365-2133.2010.09640.x","article-title":"Prevalence of androgenetic alopecia in China: a community-based study in six cities","volume":"162","author":"Wang","year":"2010","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0110","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1038\/ncb2827","article-title":"MicroRNA-205 controls neonatal expansion of skin stem cells by modulating the PI(3)K pathway","volume":"15","author":"Wang","year":"2013","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0115","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1159\/000095251","article-title":"Effect of 5\u03b1-dihydrotestosterone and testosterone on apoptosis in human dermal papilla cells","volume":"19","author":"Winiarska","year":"2006","journal-title":"Skin Pharmacol. Physiol."},{"issue":"5","key":"10.1016\/j.yexmp.2020.104589_bb0120","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s00403-009-0929-7","article-title":"Inhibition of glycogen synthase kinase-3 enhances the expression of alkaline phosphatase and insulin-like growth factor-1 in human primary dermal papilla cell culture and maintains mouse hair bulbs in organ culture","volume":"301","author":"Yamauchi","year":"2009","journal-title":"Arch. Dermatol. Res."},{"issue":"3","key":"10.1016\/j.yexmp.2020.104589_bb0125","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.jdermsci.2012.09.011","article-title":"Versican gene: regulation by the \u03b2-catenin signaling pathway plays a significant role in dermal papilla cell aggregative growth","volume":"68","author":"Yang","year":"2012","journal-title":"J. Dermatol. Sci."},{"key":"10.1016\/j.yexmp.2020.104589_bb0130","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/ng1744","article-title":"Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs","volume":"38","author":"Yi","year":"2006","journal-title":"Nat. Genet."},{"issue":"7184","key":"10.1016\/j.yexmp.2020.104589_bb0135","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/nature06642","article-title":"A skin microRNA promotes differentiation by repressing \u2018stemness\u2019","volume":"13","author":"Yi","year":"2008","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.yexmp.2020.104589_bb0140","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1005253","article-title":"Post-transcriptional regulation of keratinocyte progenitor cell expansion, differentiation and hair follicle regression by miR-22","volume":"11","author":"Yuan","year":"2015","journal-title":"PLoS Genet."},{"key":"10.1016\/j.yexmp.2020.104589_bb0145","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.stem.2011.01.014","article-title":"Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment","volume":"8","author":"Zhang","year":"2011","journal-title":"Cell Stem Cell"},{"issue":"11","key":"10.1016\/j.yexmp.2020.104589_bb0150","doi-asserted-by":"crossref","first-page":"20329","DOI":"10.1002\/jcp.28633","article-title":"miR-218-5p regulates skin and hair follicle development through Wnt\/\u03b2-catenin signaling pathway by targeting SFRP2","volume":"234","author":"Zhao","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.yexmp.2020.104589_bb0155","article-title":"Lin C (2018) miR-195-5p regulates hair follicle inductivity of dermal papilla cells by suppressing Wnt\/\u03b2-catenin activation","volume":"4924356","author":"Zhu","year":"2018","journal-title":"Biomed. Res. Int."}],"container-title":["Experimental and Molecular Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014480020308662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014480020308662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T03:07:45Z","timestamp":1757992065000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014480020308662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":31,"alternative-id":["S0014480020308662"],"URL":"https:\/\/doi.org\/10.1016\/j.yexmp.2020.104589","relation":{},"ISSN":["0014-4800"],"issn-type":[{"value":"0014-4800","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"miRNA microarray profiling in patients with androgenic alopecia and the effects of miR-133b on hair growth","name":"articletitle","label":"Article Title"},{"value":"Experimental and Molecular Pathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yexmp.2020.104589","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104589"}}