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Behav."},{"key":"10.1016\/j.yfrne.2014.09.004_b0235","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1126\/science.3024317","article-title":"A deletion truncating the gonadotropin-releasing hormone gene is responsible for hypogonadism in the hpg mouse","volume":"234","author":"Mason","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.yfrne.2014.09.004_b0240","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1126\/science.3097822","article-title":"The hypogonadal mouse: reproductive functions restored by gene therapy","volume":"234","author":"Mason","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.yfrne.2014.09.004_b0790","doi-asserted-by":"crossref","first-page":"4140","DOI":"10.1073\/pnas.0508881103","article-title":"Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2","volume":"103","author":"Matsumoto","year":"2006","journal-title":"Proc. Natl. Acad. Sci. 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(Lausanne)"},{"key":"10.1016\/j.yfrne.2014.09.004_b0615","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3389\/fendo.2013.00133","article-title":"Semaphorin signaling in the development and function of the gonadotropin hormone-releasing hormone system","volume":"4","author":"Messina","year":"2013","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.yfrne.2014.09.004_b0730","doi-asserted-by":"crossref","first-page":"4759","DOI":"10.1093\/hmg\/ddr403","article-title":"Dysregulation of Semaphorin7A\/beta1-integrin signaling leads to defective GnRH-1 cell migration, abnormal gonadal development and altered fertility","volume":"20","author":"Messina","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.yfrne.2014.09.004_b0605","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1210\/en.2009-0875","article-title":"Use of mutant mouse lines to investigate origin of gonadotropin-releasing hormone-1 neurons: lineage independent of the adenohypophysis","volume":"151","author":"Metz","year":"2010","journal-title":"Endocrinology"},{"key":"10.1016\/j.yfrne.2014.09.004_b0470","doi-asserted-by":"crossref","DOI":"10.1093\/hmg\/ddt353","article-title":"Patched1 is required in neural crest cells for the prevention of orofacial clefts","author":"Metzis","year":"2013","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.yfrne.2014.09.004_b0960","doi-asserted-by":"crossref","first-page":"4825","DOI":"10.1002\/cne.22497","article-title":"Composition of the migratory mass during development of the olfactory nerve","volume":"518","author":"Miller","year":"2010","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yfrne.2014.09.004_b0685","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1016\/j.ajhg.2013.04.008","article-title":"Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism","volume":"92","author":"Miraoui","year":"2013","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.yfrne.2014.09.004_b0145","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/0006-291X(82)90596-4","article-title":"Isolation and characterization of chicken hypothalamic luteinizing hormone-releasing hormone","volume":"107","author":"Miyamoto","year":"1982","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.yfrne.2014.09.004_b0080","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0167-0115(98)00005-6","article-title":"Chromatographic and immunological identification of GnRH (gonadotropin-releasing hormone) variants. 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Neurosci."},{"key":"10.1016\/j.yfrne.2014.09.004_b0345","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/BF00384722","article-title":"The origin of the luteinizing hormone-releasing hormone (LHRH) neurons in newts (Cynops pyrrhogaster): the effect of olfactory placode ablation","volume":"269","author":"Murakami","year":"1992","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.yfrne.2014.09.004_b0840","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1126\/science.1112103","article-title":"Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling","volume":"308","author":"Ng","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.yfrne.2014.09.004_b0690","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1111\/j.1440-169X.2007.00965.x","article-title":"Role of a transcription factor Pax6 in the developing vertebrate olfactory system","volume":"49","author":"Nomura","year":"2007","journal-title":"Dev. 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(Oxf.)"},{"key":"10.1016\/j.yfrne.2014.09.004_b0320","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1210\/en.2005-0468","article-title":"Forebrain gonadotropin-releasing hormone neuronal development: insights from transgenic medaka and the relevance to X-linked Kallmann syndrome","volume":"147","author":"Okubo","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.yfrne.2014.09.004_b0220","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s00441-006-0279-0","article-title":"Ontogeny of the GnRH systems in zebrafish brain: in situ hybridization and promoter-reporter expression analyses in intact animals","volume":"327","author":"Palevitch","year":"2007","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.yfrne.2014.09.004_b0215","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.ygcen.2009.07.001","article-title":"Cxcl12a-Cxcr4b signaling is important for proper development of the forebrain GnRH system in zebrafish","volume":"165","author":"Palevitch","year":"2010","journal-title":"Gen. 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Genet."},{"key":"10.1016\/j.yfrne.2014.09.004_b0750","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.ajhg.2013.03.024","article-title":"Loss-of-function mutations in SOX10 cause Kallmann syndrome with deafness","volume":"92","author":"Pingault","year":"2013","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.yfrne.2014.09.004_b0800","doi-asserted-by":"crossref","first-page":"17447","DOI":"10.1073\/pnas.0707173104","article-title":"Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism","volume":"104","author":"Pitteloud","year":"2007","journal-title":"Proc. Natl. Acad. Sci. 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