{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T07:43:59Z","timestamp":1719906239887},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["General and Comparative Endocrinology"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.ygcen.2013.01.007","type":"journal-article","created":{"date-parts":[[2013,2,8]],"date-time":"2013-02-08T21:47:09Z","timestamp":1360360029000},"page":"67-79","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Rab3a ablation related changes in morphology of secretory vesicles in major endocrine pancreatic cells, pituitary melanotroph cells and adrenal gland chromaffin cells in mice"],"prefix":"10.1016","volume":"185","author":[{"given":"Sa\u0161ka","family":"Lipov\u0161ek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franc","family":"Jan\u017eekovi\u010d","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerd","family":"Leitinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjan Slak","family":"Rupnik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ygcen.2013.01.007_b0005","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.ceb.2006.06.010","article-title":"Biogenesis of secretory granules","volume":"18","author":"Borgonovo","year":"2006","journal-title":"Curr. Opin. Cell Biol."},{"issue":"7","key":"10.1016\/j.ygcen.2013.01.007_b0010","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1073\/pnas.0510790103","article-title":"The unique cytoarchitecture of human pancreatic islets has implications for islet cell function","volume":"103","author":"Cabrera","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ygcen.2013.01.007_b0015","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/BF00342585","article-title":"The ultrastructural basis for the identification of cell types in the pancreatic islets. I. Guinea pig","volume":"67","author":"Caramia","year":"1965","journal-title":"Z. Zellforsch. Mikrosk. Anat."},{"issue":"5","key":"10.1016\/j.ygcen.2013.01.007_b0025","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0736-5748(89)90003-8","article-title":"The development and maturation of adrenal medullary chromaffin cells of the rat in vivo: a descriptive and quantitative study","volume":"7","author":"Coupland","year":"1989","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.ygcen.2013.01.007_b0270","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.aanat.2005.10.009","article-title":"Histomorphology and ultrastructure of pancreatic islet tissue during in vivo maturation of rat pancreas","volume":"188","author":"de F. Carvalho","year":"2006","journal-title":"Ann. Anat."},{"key":"10.1016\/j.ygcen.2013.01.007_b0030","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/jemt.1060130305","article-title":"High-pressure freezing for the preservation of biological structure: theory and practice","volume":"13","author":"Dahl","year":"1989","journal-title":"J. Electron. Microsc. Tech."},{"key":"10.1016\/j.ygcen.2013.01.007_b0035","doi-asserted-by":"crossref","first-page":"5692","DOI":"10.1073\/pnas.87.15.5692","article-title":"Association of the GTP-binding protein Rab3A with bovine adrenal chromaffin granules","volume":"87","author":"Darchen","year":"1990","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ygcen.2013.01.007_b0040","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0300-9084(00)00219-4","article-title":"Multiple aspects of Rab protein action in the secretory pathway: focus on Rab3 and Rab6","volume":"82","author":"Darchen","year":"2000","journal-title":"Biochimie"},{"key":"10.1016\/j.ygcen.2013.01.007_b0045","doi-asserted-by":"crossref","first-page":"24232","DOI":"10.1074\/jbc.M203345200","article-title":"Ca2+-dependent dephosphorylation of kinesin heavy chain on \u03b2-granules in pancreatic \u03b2-cells. Implications for regulated \u03b2-granule transport and insulin exocytosis","volume":"277","author":"Donelan","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.ygcen.2013.01.007_b0050","first-page":"629","article-title":"An immunocytochemical and morphometric study of the rat pancreatic islets","volume":"186","author":"Elayat","year":"1995","journal-title":"J. Anat."},{"issue":"4","key":"10.1016\/j.ygcen.2013.01.007_b0055","first-page":"253","article-title":"Ultrastructural immunogold study on the various cell types of cultured pancreatic islets of adult rats","volume":"59","author":"El-Naggar","year":"2000","journal-title":"Folia Morphol."},{"key":"10.1016\/j.ygcen.2013.01.007_b0060","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1006\/gcen.2000.7427","article-title":"Characterization of pancreatic endocrine cells of the European common frog, Rana temporaria","volume":"117","author":"Etayo","year":"2000","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.ygcen.2013.01.007_b0065","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1007\/s00125-011-2438-4","article-title":"Novel standards in the measurement of rat insulin granules combining electron microscopy, high-content image analysis and in silico modelling","volume":"55","author":"Fava","year":"2012","journal-title":"Diabetologia"},{"key":"10.1016\/j.ygcen.2013.01.007_b0070","doi-asserted-by":"crossref","first-page":"10971","DOI":"10.1016\/S0021-9258(19)78076-4","article-title":"Rab3C is a synaptic vesicle protein that dissociates from synaptic vesicles after stimulation of exocytosis","volume":"269","author":"Fischer von Mollard","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ygcen.2013.01.007_b0075","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1073\/pnas.87.5.1988","article-title":"Rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles","volume":"87","author":"Fischer von Mollard","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ygcen.2013.01.007_b0080","doi-asserted-by":"crossref","first-page":"2801","DOI":"10.1007\/s00018-008-8351-4","article-title":"Regulation of secretory vesicle traffic by Rab small GTPases","volume":"65","author":"Fukuda","year":"2008","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ygcen.2013.01.007_b0085","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/369493a0","article-title":"The role of Rab3A in neurotransmitter release","volume":"369","author":"Geppert","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.ygcen.2013.01.007_b0090","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1146\/annurev.neuro.21.1.75","article-title":"Rab3 and synaptotagmin: the yin and yang of synaptic membrane fusion","volume":"21","author":"Geppert","year":"1998","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.ygcen.2013.01.007_b0095","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0300-9084(00)00195-4","article-title":"Signal-mediated sorting of neuropeptides and prohormones: secretory granule biogenesis revisited","volume":"82","author":"Glombik","year":"2000","journal-title":"Biochimie"},{"key":"10.1016\/j.ygcen.2013.01.007_b0100","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.neuron.2009.04.022","article-title":"Wnt signalling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus","volume":"62","author":"Gogolla","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.ygcen.2013.01.007_b0105","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/S0092-8674(00)80585-1","article-title":"Regulation of membrane trafficking: structural insights from a Rab\/effector complex","volume":"96","author":"Gonzales","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.ygcen.2013.01.007_b0110","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1152\/jn.00316.2005","article-title":"Mouse chromaffin cells have two populations of dense core vesicles","volume":"94","author":"Grabner","year":"2005","journal-title":"J. Neurophysiol."},{"issue":"32","key":"10.1016\/j.ygcen.2013.01.007_b0115","doi-asserted-by":"crossref","first-page":"11821","DOI":"10.1073\/pnas.0601617103","article-title":"Rabs and their effectors: achieving specificity in membrane traffic","volume":"103","author":"Grosshans","year":"2006","journal-title":"PNAS"},{"key":"10.1016\/j.ygcen.2013.01.007_b0120","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1463-1326.2007.00789.x","article-title":"Secretory vesicle docking to the plasma membrane: molecular mechanism and functional significance","volume":"9","author":"Izumi","year":"2007","journal-title":"Diabetes Obes. Metab."},{"key":"10.1016\/j.ygcen.2013.01.007_b0130","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0896-6273(91)90078-E","article-title":"Rab3A attachment to the synaptic vesicle membrane mediated by a conserved polyisoprenylated carboxy-terminal sequence","volume":"7","author":"Johnston","year":"1991","journal-title":"Neuron"},{"key":"10.1016\/j.ygcen.2013.01.007_b0135","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1365-2818.1992.tb03260.x","article-title":"Artefacts and morphological changes during chemical fixation","volume":"168","author":"Kellenberger","year":"1992","journal-title":"J. Microsc."},{"issue":"2","key":"10.1016\/j.ygcen.2013.01.007_b0140","doi-asserted-by":"crossref","first-page":"165","DOI":"10.4081\/823","article-title":"An immunohistochemical study of endocrine cells in the pancreas of the Red-bellied frog (Bombina orientalis)","volume":"47","author":"Lee","year":"2003","journal-title":"Eur. J. Histochem."},{"key":"10.1016\/j.ygcen.2013.01.007_b0145","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/jcp.20938","article-title":"Visualization of Rab3A dissociation during exocytosis: a study by total internal reflection microscopy","volume":"211","author":"Lin","year":"2007","journal-title":"J. Cell. Physiol."},{"issue":"9","key":"10.1016\/j.ygcen.2013.01.007_b0150","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1210\/me.2007-0077","article-title":"Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine \u03b2-cells","volume":"21","author":"Marsh","year":"2007","journal-title":"Mol. Endocrinol."},{"issue":"12","key":"10.1016\/j.ygcen.2013.01.007_b0155","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1111\/j.1600-0854.2000.11207.x","article-title":"Rab3A and Rab3D control the total granule number and the fraction of granules docked at the plasma membrane in PC12 cells","volume":"1","author":"Martelli","year":"2001","journal-title":"Traffic"},{"key":"10.1016\/j.ygcen.2013.01.007_b0160","doi-asserted-by":"crossref","first-page":"600","DOI":"10.2337\/diabetes.55.03.06.db05-1054","article-title":"Pancreatic \u03b2-cells secrete insulin in fast- and slow-release forms","volume":"55","author":"Michael","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.ygcen.2013.01.007_b0165","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/0006-291X(89)90835-8","article-title":"Tissue distribution of smg p25A, a ras p21-like GTP-binding protein, studied by use of a specific monoclonal antibody","volume":"162","author":"Mizoguchi","year":"1989","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ygcen.2013.01.007_b0170","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1006\/bbrc.1994.2063","article-title":"Localization of Rabphilin-3A on the synaptic vesicle","volume":"202","author":"Mizoguchi","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ygcen.2013.01.007_b0175","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1247\/csf.27.421","article-title":"Autophagosome formation in mammalian cells","volume":"27","author":"Mizushima","year":"2002","journal-title":"Cell Struct. Funct."},{"key":"10.1016\/j.ygcen.2013.01.007_b0180","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.brainresrev.2008.04.006","article-title":"Rab GTPases and their roles in brain neurons and glia","volume":"58","author":"Ng","year":"2008","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.ygcen.2013.01.007_b0185","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/S0955-0674(97)80025-7","article-title":"The diversity of Rab proteins in vesicle transport","volume":"9","author":"Novick","year":"1997","journal-title":"Curr. Opin. Cell Biol."},{"issue":"10","key":"10.1016\/j.ygcen.2013.01.007_b0190","doi-asserted-by":"crossref","first-page":"e1000229","DOI":"10.1371\/journal.pbio.1000229","article-title":"Intracellular serotonin modulates insulin secretion from pancreatic \u03b2-cells by protein serotonylation","volume":"7","author":"Paulmann","year":"2009","journal-title":"PLoS Biol."},{"issue":"2","key":"10.1016\/j.ygcen.2013.01.007_b0195","doi-asserted-by":"crossref","first-page":"77","DOI":"10.4161\/sgtp.2.2.15201","article-title":"Distinct yet overlapping roles of Rab GTPases on synaptic vesicles","volume":"2","author":"Pavlos","year":"2011","journal-title":"Small GTPases"},{"key":"10.1016\/j.ygcen.2013.01.007_b0200","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1113\/jphysiol.2004.064410","article-title":"Recapture after exocytosis causes differential retention of protein in granules of bovine chromaffin cells","volume":"560","author":"Perrais","year":"2004","journal-title":"J. Physiol."},{"key":"10.1016\/j.ygcen.2013.01.007_b0205","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1007\/s00125-003-1153-1","article-title":"Insulin granule dynamics in pancreatic beta cells","volume":"46","author":"Rorsman","year":"2003","journal-title":"Diabetologia"},{"key":"10.1016\/j.ygcen.2013.01.007_b0210","doi-asserted-by":"crossref","first-page":"C98","DOI":"10.1152\/ajpcell.00005.2006","article-title":"Distinct role of Rab3a and Rab3b in secretory activity of rat melanotrophs","volume":"292","author":"Rupnik","year":"2007","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"43","key":"10.1016\/j.ygcen.2013.01.007_b0215","doi-asserted-by":"crossref","first-page":"40919","DOI":"10.1074\/jbc.M203704200","article-title":"Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion","volume":"277","author":"Schl\u00fcter","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ygcen.2013.01.007_b0220","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1111\/j.1600-0854.2010.01107.x","article-title":"Rab3 proteins involved in vesicle biogenesis and priming in embryonic mouse chromaffin cells","volume":"11","author":"Schonn","year":"2010","journal-title":"Traffic"},{"key":"10.1016\/j.ygcen.2013.01.007_b0225","unstructured":"Sedej, S., Skelin, M., Schl\u00fcter, O.M., Slak Rupnik, M., Rab3a controls the high Ca2+-affinity release of \u03b1-melanocyte stimulating hormone in murine pituitary cells, in preparation."},{"key":"10.1016\/j.ygcen.2013.01.007_b0230","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0896-6273(00)80292-5","article-title":"Function of Rab3 GDP-GTP exchange, minireview","volume":"18","author":"S\u00fcdhof","year":"1997","journal-title":"Neuron"},{"key":"10.1016\/j.ygcen.2013.01.007_b0235","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1146\/annurev.neuro.26.041002.131412","article-title":"The synaptic vesicle cycle","volume":"27","author":"S\u00fcdhof","year":"2004","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.ygcen.2013.01.007_b0240","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1046\/j.1365-2443.1996.00257.x","article-title":"Rab3A small GTP-binding protein in Ca2+-dependent exocytosis, review","volume":"1","author":"Takai","year":"1996","journal-title":"Gene Cell"},{"key":"10.1016\/j.ygcen.2013.01.007_b0245","doi-asserted-by":"crossref","first-page":"9715","DOI":"10.1074\/jbc.M211352200","article-title":"Insulin secretory deficiency and glucose intolerance in Rab3a null mice","volume":"278","author":"Yaekura","year":"2003","journal-title":"J. Biol. Chem."},{"issue":"12","key":"10.1016\/j.ygcen.2013.01.007_b0250","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1111\/j.1745-7254.2005.00235.x","article-title":"Molecular mechanism and regulation of autophagy","volume":"26","author":"Yang","year":"2005","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.ygcen.2013.01.007_b0255","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1093\/nar\/16.3.1204","article-title":"Complete coding sequences of the ras related rab 3 and 4 cDNAs","volume":"16","author":"Zahraoui","year":"1988","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ygcen.2013.01.007_b0260","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/35052055","article-title":"Rab proteins as membrane organizers","volume":"2","author":"Zerial","year":"2001","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ygcen.2013.01.007_b0265","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1016\/0006-291X(72)90769-3","article-title":"Physical and biological properties of guinea pig insulin","volume":"46","author":"Zimmerman","year":"1972","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["General and Comparative Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016648013000476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016648013000476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T19:06:44Z","timestamp":1714936004000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016648013000476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":52,"alternative-id":["S0016648013000476"],"URL":"https:\/\/doi.org\/10.1016\/j.ygcen.2013.01.007","relation":{},"ISSN":["0016-6480"],"issn-type":[{"value":"0016-6480","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}