{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:07:58Z","timestamp":1760216878537},"reference-count":38,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,5,1]],"date-time":"2004-05-01T00:00:00Z","timestamp":1083369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genomics"],"published-print":{"date-parts":[[2004,5]]},"DOI":"10.1016\/j.ygeno.2003.10.005","type":"journal-article","created":{"date-parts":[[2004,1,13]],"date-time":"2004-01-13T10:24:13Z","timestamp":1073989453000},"page":"765-771","source":"Crossref","is-referenced-by-count":13,"title":["Inconsistent susceptibility to autoimmunity in inbred LEW rats is due to genetic crossbreeding involving segregation of the arthritis-regulating gene Ncf1"],"prefix":"10.1016","volume":"83","author":[{"given":"Peter","family":"Olofsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c5sa","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Wedekind","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingrid","family":"Kl\u00f6ting","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Klinga-Levan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shemin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rikard","family":"Holmdahl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygeno.2003.10.005_BIB1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","article-title":"The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis","volume":"31","author":"Arnett","year":"1988","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB2","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.4049\/jimmunol.164.3.1564","article-title":"Evidence for common autoimmune disease genes controlling onset, severity, and chronicity based on experimental models for multiple sclerosis and rheumatoid arthritis","volume":"164","author":"Bergsteinsdottir","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB3","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1002\/eji.1830210910","article-title":"Genetic differences in the T cell receptor alleles of LEW rats and their encephalomyelitis-resistant derivative, LER, and their impact on the inheritance of EAE resistance","volume":"21","author":"Blankenhorn","year":"1991","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB4","series-title":"The Molecular Pathology of Autoimmune Diseases","author":"Bona","year":"1993"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB5","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1002\/(SICI)1097-4547(19960915)45:6<714::AID-JNR8>3.0.CO;2-B","article-title":"Possible mechanism for the TCR beta-chain associated EAE resistance of LER rats","volume":"45","author":"Bourque","year":"1996","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB6","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1073\/pnas.88.7.2753","article-title":"Autosomal recessive chronic granulomatous disease caused by deletion at a dinucleotide repeat","volume":"88","author":"Casimir","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB7","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1007\/BF00372462","article-title":"The genes for nonsusceptibility to EAE in the Le-R and BH rat strains are not linked to RT1","volume":"17","author":"Gasser","year":"1983","journal-title":"Immunogenetics"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB8","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0165-5728(93)90046-2","article-title":"The origin of the autoimmune disease-resistant LER rat: an outcross between the buffalo and autoimmune disease-prone Lewis inbred rat strains","volume":"44","author":"Goldmuntz","year":"1993","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0165-5728(94)90240-2","article-title":"Variable susceptibility of Lewis rats to experimental autoimmune encephalomyelitis","volume":"54","author":"Gould","year":"1994","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB10","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/art.1780240605","article-title":"Immunogenetic control of experimental type II collagen-induced arthritis. I. Susceptibility and resistance among inbred strains of rats","volume":"24","author":"Griffiths","year":"1981","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB11","unstructured":"H.J. Heidrich, Genetic Monitoring of Inbred Strains of Rats, VCH, Stuttgart\/New York, 1990."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB12","first-page":"879","article-title":"The susceptibility of rat strains to experimental allergic encephalomyelitis","volume":"24","author":"Hughes","year":"1973","journal-title":"Immunology"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB13","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0165-5728(94)90115-5","article-title":"Evidence for genetic contamination of inbred buffalo rats (RT-1b) obtained from a commercial vendor","volume":"52","author":"Jones","year":"1994","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB14","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1002\/eji.1830120712","article-title":"Low susceptibility to the induction of experimental autoimmune encephalomyelitis in a substrain of the otherwise susceptible Lewis rat","volume":"12","author":"Kallen","year":"1982","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB15","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/jlb.67.3.396","article-title":"Phorbol myristate acetate induces neutrophil NADPH-oxidase activity by two separate signal transduction pathways: dependent or independent of phosphatidylinositol 3-kinase","volume":"67","author":"Karlsson","year":"2000","journal-title":"J. Leukocyte Biol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB16","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s003359900511","article-title":"Comparison of genetic variability at microsatellite loci in wild rats and inbred rat strains (Rattus norvegicus)","volume":"8","author":"Kloting","year":"1997","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB17","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/417785a","article-title":"Full house","volume":"417","author":"Knight","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB18","doi-asserted-by":"crossref","first-page":"824","DOI":"10.3181\/00379727-143-37421","article-title":"Polyarthritis induced in the rat with cell walls from several bacteria and two Streptomyces species","volume":"143","author":"Koga","year":"1973","journal-title":"Proc. Soc. Exp. Biol. Med."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB19","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1042\/0264-6021:3380359","article-title":"Characterization and partial purification of a novel neutrophil membrane-associated kinase capable of phosphorylating the respiratory burst component p47phox","volume":"338","author":"Lal","year":"1999","journal-title":"Biochem. J."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB20","doi-asserted-by":"crossref","first-page":"6383","DOI":"10.1073\/pnas.95.11.6383","article-title":"Identification of rat susceptibility loci for adjuvant-oil-induced arthritis","volume":"95","author":"Lorentzen","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB21","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1038\/sj.ejhg.5200832","article-title":"Both common and unique susceptibility genes in different rat strains with pristane-induced arthritis","volume":"10","author":"Lu","year":"2002","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB22","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.4049\/jimmunol.115.5.1456","article-title":"The immune response against an encephalitogenic fragment of guinea pig basic protein in the Lewis and Brown Norway strains of rat","volume":"115","author":"McFarlin","year":"1975","journal-title":"J. Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB23","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1182\/blood.V97.1.305","article-title":"Autosomal recessive chronic granulomatous disease caused by defects in NCF-1, the gene encoding the phagocyte p47-phox: mutations not arising in the NCF-1 pseudogenes","volume":"97","author":"Noack","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/ng1058","article-title":"Positional identification of Ncf1 as a gene that regulates arthritis severity in rats","volume":"33","author":"Olofsson","year":"2003","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB25","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/BF00352364","article-title":"Use of simple sequence length polymorphisms for genetic characterization of rat inbred strains","volume":"6","author":"Otsen","year":"1995","journal-title":"Mamm. Genome"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB26","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/0008-8749(89)90096-8","article-title":"Genetic resistance in experimental autoimmune encephalomyelitis. I. Analysis of the mechanism of LeR resistance using radiation chimeras","volume":"122","author":"Pelfrey","year":"1989","journal-title":"Cell Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB27","first-page":"191","article-title":"The susceptibility of several inbred strains of rats to adjuvant-induced arthritis and experimental allergic encephalomyelitis","volume":"147","author":"Perlik","year":"1974","journal-title":"Z. Immunitatsforsch. Exp. Klin. Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB28","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1182\/blood.V95.6.2150","article-title":"Recombination events between the p47-phox gene and its highly homologous pseudogenes are the main cause of autosomal recessive chronic granulomatous disease","volume":"95","author":"Roesler","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB29","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1093\/rheumatology\/31.9.583","article-title":"Cartilage oligomeric matrix protein: a novel marker of cartilage turnover detectable in synovial fluid and blood","volume":"31","author":"Saxne","year":"1992","journal-title":"Br. J. Rheumatol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB30","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/00005792-200005000-00004","article-title":"Genetic, biochemical, and clinical features of chronic granulomatous disease","volume":"79","author":"Segal","year":"2000","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.ygeno.2003.10.005_BIB31","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1093\/intimm\/11.4.529","article-title":"Identification of genomic regions controlling experimental autoimmune uveoretinitis in rats","volume":"11","author":"Sun","year":"1999","journal-title":"Int. Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB32","unstructured":"G.E. Truett, P. Heeger, R.L. Mynatt, A.A. Truett, J.A. Walker, M.L. Warman. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and Tris (HotSHOT). Biotechniques 29 (2000) 52, 54."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB33","doi-asserted-by":"crossref","first-page":"5177","DOI":"10.4049\/jimmunol.164.10.5177","article-title":"Superoxide prevents nitric oxide-mediated suppression of helper T lymphocytes: decreased autoimmune encephalomyelitis in nicotinamide adenine dinucleotide phosphate oxidase knockout mice","volume":"164","author":"van der Veen","year":"2000","journal-title":"J. Immunol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB34","first-page":"1675","article-title":"Pristane-induced arthritis in rats: a new model for rheumatoid arthritis with a chronic disease course influenced by both major histocompatibility complex and non-major histocompatibility complex genes","volume":"149","author":"Vingsbo","year":"1996","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB35","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1038\/3887","article-title":"Genetic control of arthritis onset, severity and chronicity in a model for rheumatoid arthritis in rats","volume":"20","author":"Vingsbo-Lundberg","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB36","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1002\/1529-0131(199803)41:3<544::AID-ART21>3.0.CO;2-#","article-title":"Increased serum levels of cartilage oligomeric matrix protein in chronic erosive arthritis in rats","volume":"41","author":"Vingsbo-Lundberg","year":"1998","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB37","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1084\/jem.153.1.61","article-title":"Genetic resistance to the induction of experimental allergic encephalomyelitis in Lewis rats. I. Genetic analysis of an apparent mutant strain with phenotypic resistance to experimental allergic encephalomyelitis","volume":"153","author":"Waxman","year":"1981","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ygeno.2003.10.005_BIB38","doi-asserted-by":"crossref","first-page":"948","DOI":"10.4049\/jimmunol.162.2.948","article-title":"Identification of quantitative trait loci governing arthritis severity and humoral responses in the murine model of Lyme disease","volume":"162","author":"Weis","year":"1999","journal-title":"J. Immunol."}],"container-title":["Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754303003380?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754303003380?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T18:29:53Z","timestamp":1682620193000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0888754303003380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,5]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,5]]}},"alternative-id":["S0888754303003380"],"URL":"https:\/\/doi.org\/10.1016\/j.ygeno.2003.10.005","relation":{},"ISSN":["0888-7543"],"issn-type":[{"value":"0888-7543","type":"print"}],"subject":[],"published":{"date-parts":[[2004,5]]}}}