{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:52:44Z","timestamp":1775303564621,"version":"3.50.1"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,7,20]],"date-time":"2013-07-20T00:00:00Z","timestamp":1374278400000},"content-version":"vor","delay-in-days":2361,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genomics"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.ygeno.2006.10.001","type":"journal-article","created":{"date-parts":[[2006,11,30]],"date-time":"2006-11-30T15:10:51Z","timestamp":1164899451000},"page":"167-177","source":"Crossref","is-referenced-by-count":32,"title":["Genome-wide linkage scan of schizophrenia: A cross-isolate study"],"prefix":"10.1016","volume":"89","author":[{"given":"Kazima B.","family":"Bulayeva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J.","family":"Glatt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oleg A.","family":"Bulayev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatiana A.","family":"Pavlova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming T.","family":"Tsuang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygeno.2006.10.001_bib1","series-title":"Schizophrenia: The Epigenetic Puzzle","author":"Gottesman","year":"1982"},{"key":"10.1016\/j.ygeno.2006.10.001_bib2","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4899-0170-5_5","article-title":"The inheritance of mood disorders","author":"Tsuang","year":"1996"},{"key":"10.1016\/j.ygeno.2006.10.001_bib3","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/sj.mp.4001356","article-title":"Genome-wide scan in a large complex pedigree with predominantly male schizophrenics from the island of Kosrae: evidence for linkage to chromosome 2q","volume":"8","author":"Wijsman","year":"2003","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib4","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/ajmg.1320540108","article-title":"Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12\u2013q13.1, Part 1","volume":"54","author":"Pulver","year":"1994","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib5","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1002\/ajmg.1320600407","article-title":"Linkage analysis of chromosome 22q12\u201313 in a United Kingdom\/Icelandic sample of 23 multiplex schizophrenia families","volume":"60","author":"Kalsi","year":"1995","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib6","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1126\/science.288.5466.678","article-title":"Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22","volume":"288","author":"Brzustowicz","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.ygeno.2006.10.001_bib7","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1086\/376578","article-title":"A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain","volume":"73","author":"Bray","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib8","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1176\/appi.ajp.160.3.469","article-title":"Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies","volume":"160","author":"Glatt","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib9","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1086\/376549","article-title":"Genome scan meta-analysis of schizophrenia and bipolar disorder. Part II. Schizophrenia","volume":"73","author":"Lewis","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib10","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/ng1195-241","article-title":"Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results","volume":"11","author":"Lander","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib11","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/sj.mp.4001444","article-title":"The molecular genetics of schizophrenia: new findings promise new insights","volume":"9","author":"Owen","year":"2004","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib12","series-title":"Minority Populations: Genetics Demography and Health","first-page":"1","article-title":"Minority populations as genetic isolates: the interpretation of inbreeding results","author":"Neel","year":"1992"},{"key":"10.1016\/j.ygeno.2006.10.001_bib13","doi-asserted-by":"crossref","first-page":"2507","DOI":"10.1093\/hmg\/11.20.2507","article-title":"Gene finding in genetically isolated populations","volume":"11","author":"Heutink","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib14","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1353\/hub.2004.0003","article-title":"Genetics and population history of Caucasus populations","volume":"75","author":"Bulayeva","year":"2003","journal-title":"Hum. Biol."},{"key":"10.1016\/j.ygeno.2006.10.001_bib15","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1002\/ajhb.20531","article-title":"Ethnogenomic diversity of Caucasus","volume":"18","author":"Bulayeva","year":"2006","journal-title":"Daghestan. Am. J. Hum. Biol."},{"key":"10.1016\/j.ygeno.2006.10.001_bib16","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1002\/ajmg.b.30073","article-title":"Mapping genes of complex psychiatric diseases in Daghestan genetic isolates","volume":"132","author":"Bulayeva","year":"2005","journal-title":"Am. J. Med. Genet. B"},{"key":"10.1016\/j.ygeno.2006.10.001_bib17","series-title":"History of the Daghestan","author":"Gadjiev","year":"1996"},{"key":"10.1016\/j.ygeno.2006.10.001_bib18","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1001\/archpsyc.1994.03950110009002","article-title":"Diagnostic interview for genetic studies: rationale, unique features and training","volume":"51","author":"Nurnberger","year":"1994","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib19","first-page":"1079","article-title":"Evidence for human meiotic recombination: interference obtained through construction of a short tandem repeat-polymorphism linkage map of chromosome 19","volume":"53","author":"Weber","year":"1993","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib20","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1086\/301904","article-title":"PedCheck: a program for identifying genotype incompatibilities in linkage analysis","volume":"63","author":"O\u2019Connell","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib21","first-page":"1323","article-title":"Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker sharing statistics","volume":"58","author":"Sobel","year":"1996","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib22","doi-asserted-by":"crossref","first-page":"118","DOI":"10.2307\/2533202","article-title":"A class of tests for linkage using affected pedigree members","volume":"50","author":"Whittemore","year":"1994","journal-title":"J. Biometrics"},{"key":"10.1016\/j.ygeno.2006.10.001_bib23","series-title":"Handbook of Human Genetic Linkage","author":"Terwilliger","year":"1994"},{"key":"10.1016\/j.ygeno.2006.10.001_bib24","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1093\/hmg\/ddg302","article-title":"Recent advances in the genetics of schizophrenia","volume":"12","author":"O\u2019Donovan","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib25","first-page":"27","article-title":"Molecular genetics of schizophrenia: past, present and future","author":"Prasad","year":"2002","journal-title":"J. Biosci."},{"key":"10.1016\/j.ygeno.2006.10.001_bib26","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1093\/hmg\/10.26.3037","article-title":"Genome-wide scan in a nationwide study sample of schizophrenia families in Finland reveals susceptibility loci on chromosomes 2q and 5q","volume":"10","author":"Paunio","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib27","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1086\/380206","article-title":"A systematic genomewide linkage study in 353 sib pairs with schizophrenia","volume":"73","author":"Williams","year":"2003","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib28","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0006-3223(97)00203-5","article-title":"Genetic association between reduced P300 amplitude and the DRD2 dopamine receptor A1 allele in children at high risk for alcoholism","volume":"43","author":"Hill","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib29","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1038\/sj.mp.4001321","article-title":"Meta-analysis identifies an association between the dopamine D2 receptor gene and schizophrenia","volume":"8","author":"Glatt","year":"2003","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ajmg.b.20135","article-title":"Serotonin transporter polymorphism and depressive-related symptoms in schizophrenia","volume":"126","author":"Golimbet","year":"2004","journal-title":"Am. J. Med. Genet. B"},{"key":"10.1016\/j.ygeno.2006.10.001_bib31","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0888-7543(03)00101-0","article-title":"Molecular cloning and characterization of human RAI1, a gene associated with schizophrenia","volume":"82","author":"Toulouse","year":"2003","journal-title":"Genomics"},{"key":"10.1016\/j.ygeno.2006.10.001_bib32","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/ajmg.1320540108","article-title":"Sequential strategy to identify a susceptibility gene for schizophrenia: report of potential linkage on chromosome 22q12\u2013q13.1, Part 1","volume":"54","author":"Pulver","year":"1994","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib33","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1176\/appi.ajp.160.3.469","article-title":"Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies","volume":"160","author":"Glatt","year":"2003","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib34","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1002\/ajmg.1320600407","article-title":"Linkage analysis of chromosome 22q12\u201313 in a United Kingdom\/Icelandic sample of 23 multiplex schizophrenia families","volume":"60","author":"Kalsi","year":"1995","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib35","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/(SICI)1096-8628(19970725)74:4<361::AID-AJMG4>3.0.CO;2-S","article-title":"No evidence for a schizophrenia susceptibility gene in the vicinity of IL2RB on chromosome 22","volume":"74","author":"Parsian","year":"1997","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib36","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/(SICI)1096-8628(19961122)67:6<515::AID-AJMG2>3.0.CO;2-G","article-title":"No evidence for linkage of chromosome 22 markers to schizophrenia in southern African Bantu-speaking families","volume":"67","author":"Riley","year":"1996","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib37","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/sj.mp.4001012","article-title":"Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia","volume":"7","author":"Badner","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.ygeno.2006.10.001_bib38","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1086\/344514","article-title":"A highly significant association between a COMT haplotype and schizophrenia","volume":"71","author":"Shifman","year":"2002","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2006.10.001_bib39","doi-asserted-by":"crossref","first-page":"4680","DOI":"10.1073\/pnas.032069099","article-title":"Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22","volume":"99","author":"Mimmack","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.ygeno.2006.10.001_bib40","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/ajmg.b.20007","article-title":"Apolipoprotein E in schizophrenia: a French association study and meta-analysis","volume":"119","author":"Schurhoff","year":"2003","journal-title":"Am. J. Med. Genet. B"},{"key":"10.1016\/j.ygeno.2006.10.001_bib41","doi-asserted-by":"crossref","first-page":"4066","DOI":"10.1073\/pnas.071056198","article-title":"Increased CNS levels of apolipoprotein D in schizophrenic and bipolar subjects: implications for the pathophysiology of psychiatric disorders","volume":"98","author":"Thomas","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA."}],"container-title":["Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754306002953?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754306002953?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,22]],"date-time":"2019-04-22T17:14:58Z","timestamp":1555953298000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0888754306002953"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S0888754306002953"],"URL":"https:\/\/doi.org\/10.1016\/j.ygeno.2006.10.001","relation":{},"ISSN":["0888-7543"],"issn-type":[{"value":"0888-7543","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]}}}