{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:50:50Z","timestamp":1778932250219,"version":"3.51.4"},"reference-count":97,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"vor","delay-in-days":546,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01 DA044872"],"award-info":[{"award-number":["R01 DA044872"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genomics"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.ygeno.2021.08.013","type":"journal-article","created":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T01:22:24Z","timestamp":1629336144000},"page":"3461-3475","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["HIV-1 Tat and cocaine impact astrocytic energy reservoir influence on miRNA epigenetic regulation"],"prefix":"10.1016","volume":"113","author":[{"given":"Mayur","family":"Doke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatah","family":"Kashanchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mansoor A.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thangavel","family":"Samikkannu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygeno.2021.08.013_bb0005","series-title":"U.S. Statistics | HIV.gov, Underst. Addressing Violence against Women","first-page":"1","author":"World Health Organization","year":"2018"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0010","doi-asserted-by":"crossref","first-page":"9006","DOI":"10.1128\/JVI.79.14.9006-9018.2005","article-title":"Changes in human immunodeficiency virus type 1 fitness and genetic diversity during disease progression","volume":"79","author":"Troyer","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0015","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1007\/s11904-010-0070-4","article-title":"Pathogenesis of HIV in the central nervous system","volume":"8","author":"Valcour","year":"2011","journal-title":"Curr. HIV\/AIDS Rep."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0020","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/j.1365-2362.2006.01657.x","article-title":"Role of the pro-inflammatory cytokines TNF-\u03b1 and IL-1\u03b2 in HIV-associated dementia","volume":"36","author":"Brabers","year":"2006","journal-title":"Eur. J. Clin. Investig."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0025","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1440-1789.2008.00996.x","article-title":"In vivo expression of proinflammatory cytokines in HIV encephalitis: an analysis of 11 autopsy cases: original article","volume":"29","author":"Xing","year":"2009","journal-title":"Neuropathology."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0030","doi-asserted-by":"crossref","first-page":"12844","DOI":"10.1523\/JNEUROSCI.4154-07.2007","article-title":"Gap junctions mediate human immunodeficiency virus-bystander killing in astrocytes","volume":"27","author":"Eugenin","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0035","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1742-4690-7-33","article-title":"The macrophage in HIV-1 infection: from activation to deactivation?","volume":"7","author":"Herbein","year":"2010","journal-title":"Retrovirology."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0040","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1080\/15592294.2016.1221569","article-title":"Epigenome-wide differential DNA methylation between HIV-infected and uninfected individuals","volume":"11","author":"Zhang","year":"2016","journal-title":"Epigenetics."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106348","article-title":"Immunopathogenesis of HIV infection in cocaine users: role of arachidonic acid","volume":"9","author":"Samikkannu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0050","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0022-510X(02)00207-1","article-title":"The role of macrophage\/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis","volume":"202","author":"Minagar","year":"2002","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0055","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/0092-8674(86)90017-6","article-title":"The trans-activator gene of the human T cell lymphotropic virus type III is required for replication","volume":"44","author":"Dayton","year":"1986","journal-title":"Cell."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0060","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2174\/1570162X13666150311164201","article-title":"Mechanisms of HIV-1 tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders","volume":"13","author":"Fields","year":"2015","journal-title":"Curr. HIV Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0065","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/8910396","article-title":"Oxidative stress during HIV infection: mechanisms and consequences","volume":"2016","author":"Ivanov","year":"2016","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0070","doi-asserted-by":"crossref","DOI":"10.1038\/s41419-018-0422-3","article-title":"Astrocytic metabolic switch is a novel etiology for Cocaine and HIV-1 Tat-mediated neurotoxicity article","volume":"9","author":"Natarajaseenivasan","year":"2018","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0075","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2015.01111","volume":"6","author":"Dash","year":"2015","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0080","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1128\/CMR.16.2.209-219.2003","article-title":"Microbial infections, immunomodulation, and drugs of abuse","volume":"16","author":"Friedman","year":"2003","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0085","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1097\/00002030-200004140-00011","article-title":"Correlates of HIV infection among young adult short-term injection drug users","volume":"14","author":"Doherty","year":"2000","journal-title":"AIDS."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0090","article-title":"Deteriorating effects of cocaine abuse on brain metabolic function of HIV infected patients","volume":"57","author":"Fardin","year":"2016","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0095","doi-asserted-by":"crossref","first-page":"281","DOI":"10.31887\/DCNS.2009.11.3\/mbelanger","article-title":"The role of astroglia in neuroprotection","volume":"11","author":"B\u00e9langer","year":"2009","journal-title":"Dialogues Clin. Neurosci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0100","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.3389\/fnins.2019.01301","article-title":"Energy dynamics in the brain: contributions of astrocytes to metabolism and pH homeostasis","volume":"13","author":"Deitmer","year":"2019","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0105","first-page":"1","article-title":"HIV-tat and cocaine impact brain energy metabolism: redox modification and mitochondrial biogenesis influence NRF transcription-mediated Neurodegeneration","author":"Sivalingam","year":"2020","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0110","article-title":"HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation","author":"Doke","year":"2020","journal-title":"Epigenetics"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0115","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1203\/pdr.0b013e3180457684","article-title":"Epigenetics and microRNAs","volume":"61","author":"Chuang","year":"2007","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0120","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1146\/annurev.neuro.29.051605.113009","article-title":"Neural mechanisms of addiction: the role of reward-related learning and memory","volume":"29","author":"Hyman","year":"2006","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0125","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1016\/j.neuropharm.2011.01.036","article-title":"Synaptic plasticity and addiction: learning mechanisms gone awry","volume":"61","author":"Mameli","year":"2011","journal-title":"Neuropharmacology."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0130","doi-asserted-by":"crossref","first-page":"335","DOI":"10.31887\/DCNS.2014.16.3\/pkenny","volume":"16","author":"Kenny","year":"2014","journal-title":"Dialogues Clin. Neurosci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0135","doi-asserted-by":"crossref","first-page":"65","DOI":"10.21037\/jphe.2017.05.11","article-title":"MicroRNA profiling in plasma of HIV-1 infected patients: potential markers of infection and immune status","volume":"1","author":"Qi","year":"2017","journal-title":"J. Public Heal. Emerg."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms21186970","article-title":"Comparison of miRNA expression profiles between HIV-1 and HIV-2 infected monocyte-derived macrophages (MDMs) and peripheral blood mononuclear cells (PBMCs)","volume":"21","author":"Biswas","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0145","article-title":"Cocaine Directly Impairs Memory Extinction and Alters Brain DNA Methylation Dynamics in Honey Bees","volume":"79","author":"S\u00f8vik","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0150","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/ddr.430020505","article-title":"The nootropic concept and its prospective implications","volume":"2","author":"Giurgea","year":"1982","journal-title":"Drug Dev. Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0155","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1527-3458.2005.tb00268.x","article-title":"Piracetam: a review of pharmacological properties and clinical uses","volume":"11","author":"Winblad","year":"2005","journal-title":"CNS Drug Rev."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0160","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0252895","article-title":"Psychostimulants and opioids differentially influence the epigenetic modification of histone acetyltransferase and histone deacetylase in astrocytes","volume":"16","author":"Doke","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0165","doi-asserted-by":"crossref","first-page":"611","DOI":"10.3390\/brainsci10090611","article-title":"Neuroprotective effect of Piracetam against cocaine-induced Neuro epigenetic modification of DNA methylation in astrocytes","volume":"10","author":"Sivalingam","year":"2020","journal-title":"Brain Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0170","doi-asserted-by":"crossref","first-page":"W537","DOI":"10.1093\/nar\/gky379","article-title":"The galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update","volume":"46","author":"Afgan","year":"2018","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0175","unstructured":"S. Andrews, Babraham bioinformatics - FastQC a quality control tool for high throughput sequence data, Soil. 5 (n.d.) 47\u201381. http:\/\/www.bioinformatics.babraham.ac.uk\/projects\/fastqc\/ (accessed December 14, 2020)."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0180","author":"Krueger"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0185","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/gb-2009-10-3-r25","article-title":"Ultrafast and memory-efficient alignment of short DNA sequences to the human genome","volume":"10","author":"Langmead","year":"2009","journal-title":"Genome Biol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0190","doi-asserted-by":"crossref","DOI":"10.2202\/1544-6115.1027","article-title":"Linear models and empirical bayes methods for assessing differential expression in microarray experiments","volume":"3","author":"Smyth","year":"2004","journal-title":"Stat. Appl. Genet. Mol. Biol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0195","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1214\/16-AOAS920","article-title":"Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression","volume":"10","author":"Phipson","year":"2016","journal-title":"Ann. Appl. Stat."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0200","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkv007","article-title":"Limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0205","doi-asserted-by":"crossref","first-page":"R29","DOI":"10.1186\/gb-2014-15-2-r29","article-title":"Voom: precision weights unlock linear model analysis tools for RNA-seq read counts","volume":"15","author":"Law","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0210","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/nar\/gkr688","article-title":"MiRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades","volume":"40","author":"Friedl\u00e4nder","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0215","doi-asserted-by":"crossref","first-page":"D68","DOI":"10.1093\/nar\/gkt1181","article-title":"MiRBase: annotating high confidence microRNAs using deep sequencing data","volume":"42","author":"Kozomara","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0220","article-title":"Small noncoding RNA discovery and profiling with sRNAtools based on high-throughput sequencing","author":"Liu","year":"2019","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0225","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.jbi.2011.05.002","article-title":"MiRWalk - database: prediction of possible miRNA binding sites by \u201c walking\u201d the genes of three genomes","volume":"44","author":"Dweep","year":"2011","journal-title":"J. Biomed. Inform."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0230","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/nmeth.3485","article-title":"MiRWalk2.0: a comprehensive atlas of microRNA-target interactions","volume":"12","author":"Dweep","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0235","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1002\/pro.3715","article-title":"Toward understanding the origin and evolution of cellular organisms","volume":"28","author":"Kanehisa","year":"2019","journal-title":"Protein Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0240","article-title":"KEGG: integrating viruses and cellular organisms","author":"Kanehisa","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0245","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1093\/nar\/28.1.27","article-title":"KEGG: Kyoto encyclopedia of genes and genomes","volume":"28","author":"Kanehisa","year":"2000","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0250","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1093\/bioinformatics\/btu684","article-title":"DOSE: an R\/bioconductor package for disease ontology semantic and enrichment analysis","volume":"31","author":"Yu","year":"2015","journal-title":"Bioinformatics."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0255","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"ClusterProfiler: an R package for comparing biological themes among gene clusters","volume":"16","author":"Yu","year":"2012","journal-title":"Omi. A J. Integr. Biol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0260","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1039\/C5MB00663E","article-title":"ReactomePA: an R\/bioconductor package for reactome pathway analysis and visualization","volume":"12","author":"Yu","year":"2016","journal-title":"Mol. BioSyst."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0265","author":"Wickham"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0270","doi-asserted-by":"crossref","first-page":"3766","DOI":"10.1093\/bioinformatics\/bty410","article-title":"Using meshes for MeSH term enrichment and semantic analyses","volume":"34","author":"Yu","year":"2018","journal-title":"Bioinformatics."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0275","unstructured":"Broad Institute, Morpheus, (n.d.). https:\/\/software.broadinstitute.org\/morpheus\/ (accessed December 14, 2020)."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0280","doi-asserted-by":"crossref","first-page":"2021","DOI":"10.1097\/QAD.0000000000001160","article-title":"Plasma microRNA profiling predicts HIV-associated neurocognitive disorder","volume":"30","author":"Asahchop","year":"2016","journal-title":"AIDS"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0285","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2013.00043","article-title":"MicroRNAs and drug addiction","volume":"4","author":"Bali","year":"2013","journal-title":"Front. Genet."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0290","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1006360","article-title":"MicroRNAs upregulated during HIV infection target peroxisome biogenesis factors: Implications for virus biology, disease mechanisms and neuropathology","volume":"13","author":"Xu","year":"2017","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0295","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s13578-020-00436-w","article-title":"MicroRNA-7: expression and function in brain physiological and pathological processes","volume":"10","author":"Zhao","year":"2020","journal-title":"Cell Biosci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0300","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s11481-019-09869-8","article-title":"HIV-1 tat-induced Astrocytic extracellular vesicle miR-7 impairs synaptic architecture","volume":"15","author":"Hu","year":"2020","journal-title":"J. NeuroImmune Pharmacol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0305","first-page":"1002","volume":"23","author":"Xi","year":"2019","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0310","doi-asserted-by":"crossref","first-page":"5354","DOI":"10.1111\/jcmm.13808","article-title":"Exosomal miR-95-5p regulates chondrogenesis and cartilage degradation via histone deacetylase 2\/8","volume":"22","author":"Mao","year":"2018","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0315","doi-asserted-by":"crossref","first-page":"75038","DOI":"10.18632\/oncotarget.12602","article-title":"miR-885-5p suppresses hepatocellular carcinoma metastasis and inhibits Wnt\/\u03b2-catenin signaling pathway","volume":"7","author":"Zhang","year":"2016","journal-title":"Oncotarget"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0320","article-title":"MicroRNA-96-5p represses breast cancer proliferation and invasion through Wnt\/\u03b2-catenin signaling via targeting CTNND1","volume":"10","author":"Gao","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.jstrokecerebrovasdis.2020.105037","article-title":"MiR-139 protects against oxygen-glucose deprivation\/reoxygenation (OGD\/R)-induced nerve injury through targeting c-Jun to inhibit NLRP3 inflammasome activation","volume":"29","author":"Wang","year":"2020","journal-title":"J. Stroke Cerebrovasc. Dis."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0330","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1097\/QAD.0000000000002368","article-title":"MicroRNA biomarkers associated with type 1 myocardial infarction in HIV-positive individuals","volume":"33","author":"Yuan","year":"2019","journal-title":"AIDS."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0335","first-page":"569","article-title":"MiR-139-5p affects cell proliferation, migration and adipogenesis by targeting insulin-like growth factor 1 receptor in hemangioma stem cells","volume":"45","author":"Wu","year":"2020","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0340","doi-asserted-by":"crossref","first-page":"981","DOI":"10.2147\/OTT.S228576","article-title":"MicroRNA 885-5p inhibits hepatocellular carcinoma metastasis by repressing AEG1","volume":"13","author":"Li","year":"2020","journal-title":"Onco. Targets. Ther."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0345","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s00439-017-1858-8","article-title":"Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population","volume":"137","author":"Li","year":"2018","journal-title":"Hum. Genet."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0350","first-page":"707","article-title":"Prediction and analysis of SOCS1 SNPs in the pathogenesis of multiple sclerosis with the alternation of some microRNAs binding sites","volume":"5","author":"Kakhki","year":"2014","journal-title":"J. North Khorasan Univ. Med. Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0355","series-title":"Elucidating the consequence and cause of microRNA Elucidating the consequence and cause of microRNA dysregulation in amyotrophic lateral sclerosis (ALS) dysregulation in amyotrophic lateral sclerosis (ALS)","author":"Hawley","year":"2020"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0360","doi-asserted-by":"crossref","first-page":"451","DOI":"10.3389\/fpls.2015.00451","article-title":"NPK macronutrients and microRNA homeostasis","volume":"6","author":"Kulcheski","year":"2015","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0365","doi-asserted-by":"crossref","DOI":"10.3390\/biomedicines9030321","article-title":"Characterization of differentially expressed circulating mirnas in metabolically healthy versus unhealthy obesity","volume":"9","author":"Rovira-Llopis","year":"2021","journal-title":"Biomedicines"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0370","author":"Duly"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0375","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cell.2004.12.035","article-title":"Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets","volume":"120","author":"Lewis","year":"2005","journal-title":"Cell."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0380","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1582-4934.2008.00556.x","article-title":"miR-21: A small multi-faceted RNA","volume":"13","author":"Krichevsky","year":"2009","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0385","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1084\/jem.20131244","article-title":"Broadly neutralizing antibodies that inhibit HIV-1 cell to cell transmission","volume":"210","author":"Malbec","year":"2013","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0390","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1038\/nrmicro1972","article-title":"Avoiding the void: cell-to-cell spread of human viruses","volume":"6","author":"Sattentau","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0395","first-page":"1501","article-title":"Interventions for HIV and Hepatitis C Virus Infections in Recreational Drug Users","volume":"50","author":"Mayer","year":"2010","journal-title":"Clinical Infectious Diseases"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0400","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0405","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18040840","article-title":"Coordinated actions of microRNAs with other epigenetic factors regulate skeletal muscle development and adaptation","volume":"18","author":"Bianchi","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0410","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.3389\/fonc.2019.01293","article-title":"Epigenetic regulation of miRNA expression in malignant mesothelioma: miRNAs as biomarkers of early diagnosis and therapy","volume":"9","author":"Tomasetti","year":"2019","journal-title":"Front. Oncol."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0415","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0225186","article-title":"Mineral absorption is an enriched pathway in a brain region of restless legs syndrome patients with reduced MEIS1 expression","volume":"14","author":"Sarayloo","year":"2019","journal-title":"PLoS One"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0420","first-page":"1","article-title":"Supplementary online content eAppendix 1","author":"Me","year":"2016","journal-title":"Members of the Schizophrenia Working Group of the Psychiatric"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0425","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.ajhg.2018.10.006","article-title":"NFIB Haploinsufficiency Is Associated with Intellectual Disability and Macrocephaly","volume":"103","author":"Schanze","year":"2018","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0430","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/j.ajhg.2019.02.016","article-title":"Mutations in the Neuronal Vesicular SNARE VAMP2 Affect Synaptic Membrane Fusion and Impair Human Neurodevelopment","volume":"104","author":"Salpietro","year":"2019","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0435","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13073-017-0452-y","article-title":"Novel promoters and coding first exons in DLG2 linked to developmental disorders and intellectual disability","volume":"9","author":"Reggiani","year":"2017","journal-title":"Genome Med."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0440","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.50416","article-title":"PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins","volume":"8","author":"Berndsen","year":"2019","journal-title":"Elife."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0445","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.neuroscience.2010.04.056","article-title":"Dopamine receptor expression and distribution dynamically change in the rat nucleus accumbens after withdrawal from cocaine self-administration","volume":"169","author":"Conrad","year":"2010","journal-title":"Neuroscience."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0450","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.neuron.2011.02.010","article-title":"How addictive drugs disrupt presynaptic dopamine neurotransmission","volume":"69","author":"Sulzer","year":"2011","journal-title":"Neuron."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0455","first-page":"578","article-title":"MicroRNA in schizophrenia: genetic and expression analysis of miR-130b (22q11)","volume":"72","author":"Burmistrova","year":"2007","journal-title":"Biochem."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0460","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.biopsych.2010.09.039","article-title":"Altered MicroRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder","volume":"69","author":"Moreau","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0465","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1261\/rna.2775511","article-title":"microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs","volume":"17","author":"Eipper-Mains","year":"2011","journal-title":"RNA"},{"key":"10.1016\/j.ygeno.2021.08.013_bb0470","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1021\/cr500457h","article-title":"Sirtuins in epigenetic regulation","volume":"115","author":"Jing","year":"2015","journal-title":"Chem. Rev."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0475","doi-asserted-by":"crossref","first-page":"3359","DOI":"10.1038\/onc.2016.485","article-title":"Interplay between epigenetics and metabolism in oncogenesis: mechanisms and therapeutic approaches","volume":"36","author":"Wong","year":"2017","journal-title":"Oncogene."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0480","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1182\/blood-2003-09-3071","article-title":"Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors","volume":"104","author":"Yusuf","year":"2004","journal-title":"Blood."},{"key":"10.1016\/j.ygeno.2021.08.013_bb0485","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.cell.2006.03.046","article-title":"A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span","volume":"125","author":"Lehtinen","year":"2006","journal-title":"Cell."}],"container-title":["Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754321003207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754321003207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T06:30:32Z","timestamp":1760164232000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0888754321003207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":97,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S0888754321003207"],"URL":"https:\/\/doi.org\/10.1016\/j.ygeno.2021.08.013","relation":{},"ISSN":["0888-7543"],"issn-type":[{"value":"0888-7543","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HIV-1 Tat and cocaine impact astrocytic energy reservoir influence on miRNA epigenetic regulation","name":"articletitle","label":"Article Title"},{"value":"Genomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygeno.2021.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc.","name":"copyright","label":"Copyright"}]}}