{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T03:30:19Z","timestamp":1790307019776,"version":"4.1.0"},"reference-count":64,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,19]],"date-time":"2025-03-19T00:00:00Z","timestamp":1742342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010256","name":"Guangzhou Municipal Science and Technology Project","doi-asserted-by":"publisher","award":["2024B03J1353"],"award-info":[{"award-number":["2024B03J1353"]}],"id":[{"id":"10.13039\/501100010256","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFD1300100"],"award-info":[{"award-number":["2021YFD1300100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genomics"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.ygeno.2025.111035","type":"journal-article","created":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T10:24:08Z","timestamp":1742552648000},"page":"111035","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Transcriptome and metabolome reveal the mechanism of neuroendocrine regulation in ovarian development of broiler breeders"],"prefix":"10.1016","volume":"117","author":[{"given":"Xiaoli","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chutian","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiming","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhexia","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuerong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aijun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiquan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingbin","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygeno.2025.111035_bb0005","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1146\/annurev-animal-022513-114132","article-title":"Evolution of the modern broiler and feed efficiency","volume":"2","author":"Siegel","year":"2014","journal-title":"Annu Rev Anim Biosci"},{"key":"10.1016\/j.ygeno.2025.111035_bb0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.101957","article-title":"Evolution of maternal feed restriction practices over 60 years of selection for broiler productivity","volume":"101","author":"Carney","year":"2022","journal-title":"Poult. Sci."},{"issue":"Suppl. 1","key":"10.1016\/j.ygeno.2025.111035_bb0015","article-title":"Review: physiological growth trend of current meat broilers and dietary protein and energy management approaches for sustainable broiler production","volume":"15","author":"Maharjan","year":"2021","journal-title":"Animal"},{"key":"10.1016\/j.ygeno.2025.111035_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102942","article-title":"Effects of energy restriction during growing phase on the productive performance of Hyline Brown laying hens aged 6 to 72 wk","volume":"102","author":"Lu","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0025","doi-asserted-by":"crossref","first-page":"707","DOI":"10.3389\/fphys.2020.00707","article-title":"Should I lay or should I grow: photoperiodic versus metabolic cues in chickens","volume":"11","author":"Hanlon","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0030","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.anireprosci.2008.09.017","article-title":"Intra-ovarian growth factors regulating ovarian function in avian species: a review","volume":"111","author":"Onagbesan","year":"2009","journal-title":"Anim. Reprod. Sci."},{"issue":"Suppl. 4","key":"10.1016\/j.ygeno.2025.111035_bb0035","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1439-0531.2012.02087.x","article-title":"Follicle selection in the avian ovary","volume":"47","author":"Johnson","year":"2012","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.ygeno.2025.111035_bb0040","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1002\/jez.a.306","article-title":"Interactions of gonadotropin-releasing hormone (GnRH) and gonadotropin-inhibitory hormone (GnIH) in birds and mammals","volume":"305","author":"Bentley","year":"2006","journal-title":"J. Exp. Zool. A Comp. Exp. Biol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2020.110914","article-title":"Discovery of gonadotropin-inhibitory hormone (GnIH), progress in GnIH research on reproductive physiology and behavior and perspective of GnIH research on neuroendocrine regulation of reproduction","volume":"514","author":"Tsutsui","year":"2020","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0050","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1210\/endo.142.7.8240","article-title":"Regulation of steroidogenic acute regulatory protein and luteinizing hormone receptor messenger ribonucleic acid in hen granulosa cells","volume":"142","author":"Johnson","year":"2001","journal-title":"Endocrinology"},{"key":"10.1016\/j.ygeno.2025.111035_bb0055","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3389\/fnins.2013.00038","article-title":"Neuroendocrine regulation of gonadotropin secretion in seasonally breeding birds","volume":"7","author":"Ubuka","year":"2013","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0060","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1530\/REP-08-0406","article-title":"Expression of anti-Mullerian hormone in hens selected for different ovulation rates","volume":"137","author":"Johnson","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.ygeno.2025.111035_bb0065","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.3382\/ps.0711750","article-title":"Effect of feed allowance during rearing and breeding on female broiler breeders. 2. Ovarian morphology and production","volume":"71","author":"Yu","year":"1992","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0070","doi-asserted-by":"crossref","first-page":"6248","DOI":"10.3390\/cimb46060373","article-title":"The omics revolution in understanding chicken reproduction: a comprehensive review","volume":"46","author":"Wadood","year":"2024","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.anireprosci.2020.106354","article-title":"The \u2018omics\u2019 revolution: use of genomic, transcriptomic, proteomic and metabolomic tools to predict male reproductive traits that impact fertility in livestock and poultry","volume":"220","author":"Long","year":"2020","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0080","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.anireprosci.2008.09.017","article-title":"Intra-ovarian growth factors regulating ovarian function in avian species: a review","volume":"111","author":"Onagbesan","year":"2009","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0085","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nmeth.3317","article-title":"HISAT: a fast spliced aligner with low memory requirements","volume":"12","author":"Kim","year":"2015","journal-title":"Nat. Methods"},{"key":"10.1016\/j.ygeno.2025.111035_bb0090","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/nbt.3122","article-title":"StringTie enables improved reconstruction of a transcriptome from RNA-seq reads","volume":"33","author":"Pertea","year":"2015","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0095","doi-asserted-by":"crossref","first-page":"R106","DOI":"10.1186\/gb-2010-11-10-r106","article-title":"Differential expression analysis for sequence count data","volume":"11","author":"Anders","year":"2010","journal-title":"Genome Biol."},{"issue":"Suppl. 4","key":"10.1016\/j.ygeno.2025.111035_bb0100","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1439-0531.2012.02087.x","article-title":"Follicle selection in the avian ovary","volume":"47","author":"Johnson","year":"2012","journal-title":"Reprod. Domest. Anim."},{"key":"10.1016\/j.ygeno.2025.111035_bb0105","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ygcen.2008.11.012","article-title":"Dynamics of avian ovarian follicle development: cellular mechanisms of granulosa cell differentiation","volume":"163","author":"Johnson","year":"2009","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0110","doi-asserted-by":"crossref","first-page":"781","DOI":"10.3382\/ps\/peu008","article-title":"Ovarian follicle selection and granulosa cell differentiation","volume":"94","author":"Johnson","year":"2015","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0115","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/jez.1402320316","article-title":"Regulation of the follicular hierarchy and ovulation","volume":"232","author":"Bahr","year":"1984","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.ygeno.2025.111035_bb0120","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1002\/jez.2649","article-title":"Seasonality in tropical birds","volume":"337","author":"Renthlei","year":"2022","journal-title":"J. Exp. Zool. A Ecol. Integr. Physiol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0125","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ygcen.2014.11.020","article-title":"Deep-brain photoreceptors (DBPs) involved in the photoperiodic gonadal response in an avian species, Gallus gallus","volume":"211","author":"Kang","year":"2015","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0130","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.813881","article-title":"OPN5 regulating mechanism of follicle development through the TSH-DIO2\/DIO3 pathway in mountain ducks under different photoperiods","volume":"13","author":"Liufu","year":"2022","journal-title":"Front. Physiol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0135","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3389\/fendo.2020.00303","article-title":"Hypothalamic-pituitary-thyroid Axis crosstalk with the hypothalamic-pituitary-gonadal Axis and metabolic regulation in the Eurasian tree sparrow during mating and non-mating periods","volume":"11","author":"Nabi","year":"2020","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.ygeno.2025.111035_bb0140","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0739-7240(03)00048-1","article-title":"Vasotocin and reproductive functions of the domestic chicken","volume":"25","author":"Jurkevich","year":"2003","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0145","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.physbeh.2016.07.001","article-title":"Expression of arginine vasotocin and estrogen receptor alpha (ERalpha) in the shell gland altered by the specific phase relations of neural oscillations affects the reproductive physiology of Japanese quail","volume":"165","author":"Srivastava","year":"2016","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.ygeno.2025.111035_bb0150","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0016-6480(90)90048-Q","article-title":"Vasoactive intestinal peptide is a hypothalamic prolactin-releasing neuropeptide in the Turkey (Meleagris gallopavo)","volume":"78","author":"El","year":"1990","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0155","doi-asserted-by":"crossref","first-page":"3562","DOI":"10.1210\/en.2016-1141","article-title":"Characterization of neuropeptide B (NPB), neuropeptide W (NPW), and their receptors in chickens: evidence for NPW being a novel inhibitor of pituitary GH and prolactin secretion","volume":"157","author":"Bu","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.ygeno.2025.111035_bb0160","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.anireprosci.2007.02.005","article-title":"Endocrine regulations of reproductive seasonality, follicular development and incubation in Magang geese","volume":"104","author":"Huang","year":"2008","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0165","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1080\/00071668.2012.719147","article-title":"Changes in plasma gonadotrophins, 17beta-oestradiol, progesterone, prolactin, thyroxine and triiodothyronine concentrations in female Japanese quail (Coturnix coturnix japonica) of a heavy body weight line during photo-induced ovarian growth and regression","volume":"53","author":"Henare","year":"2012","journal-title":"Br. Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0170","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.domaniend.2011.03.002","article-title":"Prolactin plays a stimulatory role in ovarian follicular development and egg laying in chicken hens","volume":"41","author":"Li","year":"2011","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0175","doi-asserted-by":"crossref","first-page":"4809","DOI":"10.1080\/10495398.2023.2196551","article-title":"Endocrine and molecular regulation mechanisms of follicular development and egg-laying in quails under different photoperiods","volume":"34","author":"Zhou","year":"2023","journal-title":"Anim. Biotechnol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0180","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22158056","article-title":"Matrix metalloproteinases (MMPs) and inhibitors of MMPs in the avian reproductive system: an overview","volume":"22","author":"Hrabia","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0185","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1095\/biolreprod.113.114249","article-title":"Expression and regulation of MMP1, MMP3, and MMP9 in the chicken ovary in response to gonadotropins, sex hormones, and TGFB1","volume":"90","author":"Zhu","year":"2014","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ygeno.2025.111035_bb0190","doi-asserted-by":"crossref","first-page":"327","DOI":"10.17221\/31\/2022-CJAS","article-title":"Ovary transcriptome profiling in high- and low-yielding Chinese Chahua laying chickens","volume":"67","author":"Du","year":"2022","journal-title":"Czeh J. Anim. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0195","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/mrd.1127","article-title":"Molecular cloning and partial characterization of medaka fish stromelysin-3 and its restricted expression in the oocytes of small growing follicles of the ovary","volume":"61","author":"Ogiwara","year":"2002","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.ygeno.2025.111035_bb0200","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1530\/REP-10-0211","article-title":"Bone morphogenetic protein 2 inhibits FSH responsiveness in hen granulosa cells","volume":"140","author":"Haugen","year":"2010","journal-title":"Reproduction"},{"key":"10.1016\/j.ygeno.2025.111035_bb0205","doi-asserted-by":"crossref","first-page":"E973","DOI":"10.1152\/ajpendo.00104.2003","article-title":"BMPs and BMPRs in chicken ovary and effects of BMP-4 and -7 on granulosa cell proliferation and progesterone production in vitro","volume":"285","author":"Onagbesan","year":"2003","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.ygeno.2025.111035_bb0210","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.psj.2020.10.024","article-title":"Differential analysis of gut microbiota and the effect of dietary enterococcus faecium supplementation in broiler breeders with high or low laying performance","volume":"100","author":"Wang","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102227","article-title":"Expression of GnIH and its effects on follicle development and steroidogenesis in quail ovaries under different photoperiods","volume":"101","author":"Zhou","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0220","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1677\/JOE-07-0143","article-title":"Expression and biological effects of bone morphogenetic protein-15 in the hen ovary","volume":"194","author":"Elis","year":"2007","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0225","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1530\/REP-09-0071","article-title":"Testosterone stimulates progesterone production and STAR, P450 cholesterol side-chain cleavage and LH receptor mRNAs expression in hen (Gallus domesticus) granulosa cells","volume":"138","author":"Rangel","year":"2009","journal-title":"Reproduction"},{"key":"10.1016\/j.ygeno.2025.111035_bb0230","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.anireprosci.2004.07.002","article-title":"Testosterone immunization blocks the ovulatory process in laying hens without affecting ovarian follicular development","volume":"86","author":"Rangel","year":"2005","journal-title":"Anim. Reprod. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0235","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1530\/rep.1.01067","article-title":"Testosterone antagonist (flutamide) blocks ovulation and preovulatory surges of progesterone, luteinizing hormone and oestradiol in laying hens","volume":"131","author":"Rangel","year":"2006","journal-title":"Reproduction"},{"key":"10.1016\/j.ygeno.2025.111035_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2021.145928","article-title":"Molecular characterization, expression profile and transcriptional regulation of the CYP19 gene in goose ovarian follicles","volume":"806","author":"Deng","year":"2022","journal-title":"Gene"},{"key":"10.1016\/j.ygeno.2025.111035_bb0245","article-title":"Characterization of ovarian follicles, serum steroid hormone concentration, and steroidogenic gene expression profiles in the developing ovarian follicles in white king pigeons","volume":"102","author":"Wang","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.103241","article-title":"Transcriptome profiling reveals SLC5A5 regulates chicken ovarian follicle granulosa cell proliferation, apoptosis, and steroid hormone synthesis","volume":"103","author":"Shen","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0255","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.theriogenology.2021.10.013","article-title":"Transcriptional downregulation of ABC transporters is related to follicular degeneration after vitrification and in vitro culture of ovine ovarian tissue","volume":"177","author":"Sales","year":"2022","journal-title":"Theriogenology"},{"key":"10.1016\/j.ygeno.2025.111035_bb0260","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1095\/biolreprod35.5.1096","article-title":"Ovarian steroidogenesis during follicular maturation in the domestic fowl (Gallus domesticus)","volume":"35","author":"Robinson","year":"1986","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.ygeno.2025.111035_bb0265","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1006\/gcen.1996.0019","article-title":"Steroid metabolism in theca externa cells from preovulatory follicles of domestic hen (Gallus domesticus)","volume":"101","author":"Rodriguez-Maldonado","year":"1996","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102292","article-title":"Transcriptomic analysis of the thyroid and ovarian stroma reveals key pathways and potential candidate genes associated with egg production in ducks","volume":"102","author":"He","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.ygeno.2025.111035_bb0275","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1186\/s12864-023-09895-0","article-title":"Transcriptome analysis of hypothalamus and pituitary tissues reveals genetic mechanisms associated with high egg production rates in Changshun green-shell laying hens","volume":"24","author":"Xu","year":"2023","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ygeno.2025.111035_bb0280","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1186\/s12864-021-07688-x","article-title":"Transcriptome analysis of ovary tissues from low- and high-yielding Changshun green-shell laying hens","volume":"22","author":"Mu","year":"2021","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ygeno.2025.111035_bb0285","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.fertnstert.2007.11.031","article-title":"Increased acylation-stimulating protein, C-reactive protein, and lipid levels in young women with polycystic ovary syndrome","volume":"91","author":"Wu","year":"2009","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ygeno.2025.111035_bb0290","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1186\/s12902-024-01801-3","article-title":"The relationship between serum CTRP-5, C3a\/desArg, and complement-C3 levels and hypothyroidism in women with polycystic ovary syndrome","volume":"24","author":"Abdul-Ameer","year":"2024","journal-title":"BMC Endocr. Disord."},{"key":"10.1016\/j.ygeno.2025.111035_bb0295","doi-asserted-by":"crossref","first-page":"199","DOI":"10.3945\/an.113.004747","article-title":"Obesity-induced dysfunctions in female reproduction: lessons from birds and mammals","volume":"5","author":"Walzem","year":"2014","journal-title":"Adv. Nutr."},{"key":"10.1016\/j.ygeno.2025.111035_bb0300","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.steroids.2010.01.020","article-title":"The interplay between bioactive sphingolipids and steroid hormones","volume":"75","author":"Lucki","year":"2010","journal-title":"Steroids"},{"key":"10.1016\/j.ygeno.2025.111035_bb0305","doi-asserted-by":"crossref","DOI":"10.3390\/genes13091516","article-title":"Mechanism of SCD participation in lipid droplet-mediated steroidogenesis in goose granulosa cells","volume":"13","author":"Yuan","year":"2022","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.ygeno.2025.111035_bb0310","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.domaniend.2016.05.001","article-title":"Characteristics, tissue-specific expression, and hormonal regulation of expression of tyrosine aminotransferase in the avian female reproductive tract","volume":"57","author":"Lim","year":"2016","journal-title":"Domest. Anim. Endocrinol."},{"key":"10.1016\/j.ygeno.2025.111035_bb0315","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.fertnstert.2012.06.008","article-title":"Sphingosine-1-phosphate inhibits H2O2-induced granulosa cell apoptosis via the PI3K\/Akt signaling pathway","volume":"98","author":"Nakahara","year":"2012","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ygeno.2025.111035_bb0320","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ygcen.2016.06.029","article-title":"Sphingosine-1-phosphate, regulated by FSH and VEGF, stimulates granulosa cell proliferation","volume":"236","author":"Hernandez-Coronado","year":"2016","journal-title":"Gen. Comp. Endocrinol."}],"container-title":["Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754325000515?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754325000515?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T03:27:55Z","timestamp":1762313275000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0888754325000515"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":64,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["S0888754325000515"],"URL":"https:\/\/doi.org\/10.1016\/j.ygeno.2025.111035","relation":{},"ISSN":["0888-7543"],"issn-type":[{"value":"0888-7543","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptome and metabolome reveal the mechanism of neuroendocrine regulation in ovarian development of broiler breeders","name":"articletitle","label":"Article Title"},{"value":"Genomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygeno.2025.111035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111035"}}