{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T09:32:50Z","timestamp":1793007170515,"version":"4.5.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014761","name":"Natural Science Foundation of Qingdao","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014761","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Genomics"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.ygeno.2026.111328","type":"journal-article","created":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T14:19:10Z","timestamp":1792333150000},"page":"111328","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unveiling the long non-coding RNA profile of Aeromonas veronii-infected mouse abdominal macrophages"],"prefix":"10.1016","volume":"118","author":[{"given":"Haichao","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiqing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxiao","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygeno.2026.111328_bb0005","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202009045","article-title":"LNCcation: lncRNA localization and function","volume":"220","author":"Bridges","year":"2021","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0010","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/nrm.2017.104","article-title":"The functions and unique features of long intergenic non-coding RNA","volume":"19","author":"Ransohoff","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011340","article-title":"Roles of long non-coding RNAs in plant immunity","volume":"19","author":"Huang","year":"2023","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ygeno.2026.111328_bb0020","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/s41576-023-00662-1","article-title":"Non-coding RNAs in disease: from mechanisms to therapeutics","volume":"25","author":"Nemeth","year":"2024","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.ygeno.2026.111328_bb0025","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.gpb.2016.03.005","article-title":"Long non-coding RNAs in the cytoplasm","volume":"14","author":"Rashid","year":"2016","journal-title":"Genom. Proteom. Bioinformat."},{"key":"10.1016\/j.ygeno.2026.111328_bb0030","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s12943-022-01539-3","article-title":"Long non-coding RNA LINC00680 functions as a ceRNA to promote esophageal squamous cell carcinoma progression through the miR-423-5p\/PAK6 axis","volume":"21","author":"Xue","year":"2022","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.ygeno.2026.111328_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.128558","article-title":"Non-coding RNAs modulate pyroptosis in myocardial ischemia-reperfusion injury: a comprehensive review","volume":"257","author":"Sun","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0040","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1007\/s10571-022-01210-x","article-title":"Long non-coding RNAs in retinal ganglion cell apoptosis","volume":"43","author":"Zhang","year":"2023","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0045","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.00762","article-title":"A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics","volume":"2","author":"Rapicavoli","year":"2013","journal-title":"Elife"},{"key":"10.1016\/j.ygeno.2026.111328_bb0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.imbio.2021.152133","article-title":"Long non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4\/NF-\u03baB pathway","volume":"226","author":"Liu","year":"2021","journal-title":"Immunobiology"},{"key":"10.1016\/j.ygeno.2026.111328_bb0055","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/imr.13031","article-title":"Epigenetic regulation of natural killer cell memory","volume":"305","author":"Lau","year":"2022","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.ygeno.2026.111328_bb0060","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.it.2015.07.004","article-title":"Boosting vaccine efficacy the natural (killer) way","volume":"36","author":"Rydyznski","year":"2015","journal-title":"Trends Immunol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0065","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1038\/s41423-019-0280-7","article-title":"A host lncRNA regulates the innate immune response to an RNA virus","volume":"16","author":"Fukushima","year":"2019","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0070","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/s41419-020-2323-5","article-title":"Silencing lncRNA Lfar1 alleviates the classical activation and pyoptosis of macrophage in hepatic fibrosis","volume":"11","author":"Zhang","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.ygeno.2026.111328_bb0075","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1080\/15384101.2020.1867788","article-title":"LncRNA MIAT downregulates IL-1\u03b2, TNF-\u03b1 to suppress macrophage inflammation but is suppressed by ATP-induced NLRP3 inflammasome activation","volume":"20","author":"Wang","year":"2021","journal-title":"Cell Cycle"},{"key":"10.1016\/j.ygeno.2026.111328_bb0080","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/s12864-022-08402-1","article-title":"Analysis of global Aeromonas veronii genomes provides novel information on source of infection and virulence in human gastrointestinal diseases","volume":"23","author":"Liu","year":"2022","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ygeno.2026.111328_bb0085","doi-asserted-by":"crossref","first-page":"3442","DOI":"10.1111\/1462-2920.14390","article-title":"Aeromonas veronii and aerolysin are important for the pathogenesis of motile aeromonad septicemia in cyprinid fish","volume":"20","author":"Ran","year":"2018","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0090","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1182\/blood.2019003990","article-title":"The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice","volume":"136","author":"Wu","year":"2020","journal-title":"Blood"},{"key":"10.1016\/j.ygeno.2026.111328_bb0095","doi-asserted-by":"crossref","DOI":"10.1172\/JCI193793","article-title":"Macrophage transition to a myofibroblast state drives fibrotic disease in uropathogenic E. coli-induced epididymo-orchitis","volume":"135","author":"Wang","year":"2025","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ygeno.2026.111328_bb0100","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2419567","article-title":"PPAR\u03b1 exacerbates Salmonella typhimurium infection by modulating the immunometabolism and macrophage polarization","volume":"16","author":"Taddeo","year":"2024","journal-title":"Gut Microbes"},{"key":"10.1016\/j.ygeno.2026.111328_bb0105","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/s41586-024-07614-7","article-title":"Molecular definition of the endogenous toll-like receptor signalling pathways","volume":"631","author":"Fisch","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.ygeno.2026.111328_bb0110","doi-asserted-by":"crossref","first-page":"7077","DOI":"10.4049\/jimmunol.1002165","article-title":"Differential regulation of caspase-1 activation via NLRP3\/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection","volume":"185","author":"McCoy","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0115","doi-asserted-by":"crossref","DOI":"10.1038\/s41541-025-01339-y","article-title":"Comparative evaluation of 5 combination adjuvants on immunogenicity and efficacy of approved seasonal influenza vaccines","volume":"11","author":"Hernandez-Davies","year":"2026","journal-title":"NPJ Vaccines"},{"key":"10.1016\/j.ygeno.2026.111328_bb0120","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1111\/jfd.13760","article-title":"Critical roles of VipB protein on virulence and oxidative stress tolerance in Aeromonas veronii","volume":"46","author":"Song","year":"2023","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.ygeno.2026.111328_bb0125","first-page":"3","volume":"49","year":"2000","journal-title":"MMWR Recomm. Rep."},{"key":"10.1016\/j.ygeno.2026.111328_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.micpath.2024.106820","article-title":"Integration analysis of miRNA-mRNA uncovers the molecular immune mechanism of macrophage response to Aeromonas veronii infection","volume":"194","author":"Song","year":"2024","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ygeno.2026.111328_bb0135","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.ygeno.2026.111328_bb0140","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-1-0716-1795-3_4","article-title":"RNA-seq data analysis for differential expression","volume":"2391","author":"Gill","year":"2022","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0145","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s11427-024-2989-x","article-title":"Transcriptome-wide identification of glycoRNAs by Clier-seq pipeline","volume":"69","author":"Zhu","year":"2026","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.ygeno.2026.111328_bb0150","article-title":"RNA-Seq methods for transcriptome analysis","volume":"8","author":"Hrdlickova","year":"2017","journal-title":"Wiley Interdiscip. Rev.: RNA"},{"key":"10.1016\/j.ygeno.2026.111328_bb0155","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2105-12-323","article-title":"RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome","volume":"12","author":"Li","year":"2011","journal-title":"BMC Bioinformat."},{"key":"10.1016\/j.ygeno.2026.111328_bb0160","doi-asserted-by":"crossref","first-page":"7231","DOI":"10.1038\/s41598-018-25103-6","article-title":"Whole-transcriptome analysis of atrophic ovaries in broody chickens reveals regulatory pathways associated with proliferation and apoptosis","volume":"8","author":"Liu","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ygeno.2026.111328_bb0165","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3892\/ol.2020.11575","article-title":"Prognostic prediction of a 12-methylation gene-based risk score system on pancreatic adenocarcinoma","volume":"20","author":"Dou","year":"2020","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.ygeno.2026.111328_bb0170","doi-asserted-by":"crossref","first-page":"3787","DOI":"10.1093\/bioinformatics\/bti430","article-title":"Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary","volume":"21","author":"Mao","year":"2005","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ygeno.2026.111328_bb0175","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1186\/s12864-021-07780-2","article-title":"Identification and characterization of immune-related lncRNAs and lncRNA-miRNA-mRNA networks of Paralichthys olivaceus involved in vibrio anguillarum infection","volume":"22","author":"Ning","year":"2021","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ygeno.2026.111328_bb0180","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1186\/s12864-022-08997-5","article-title":"Analysis of long non-coding RNA expression profile of bovine monocyte-macrophage infected by Mycobacterium avium subsp. paratuberculosis","volume":"23","author":"Bao","year":"2022","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ygeno.2026.111328_bb0185","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/nrrheum.2015.169","article-title":"TNF biology, pathogenic mechanisms and emerging therapeutic strategies","volume":"12","author":"Kalliolias","year":"2016","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0190","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.smim.2014.05.004","article-title":"Regulation of NF-\u03baB by TNF family cytokines","volume":"26","author":"Hayden","year":"2014","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0195","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.it.2023.05.007","article-title":"Cell death checkpoints in the TNF pathway","volume":"44","author":"Huyghe","year":"2023","journal-title":"Trends Immunol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0200","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1016\/j.cell.2023.04.025","article-title":"A 360\u00b0 view of the inflammasome: mechanisms of activation, cell death, and diseases","volume":"186","author":"Barnett","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.ygeno.2026.111328_bb0205","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/nature10759","article-title":"Inflammasomes in health and disease","volume":"481","author":"Strowig","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.ygeno.2026.111328_bb0210","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.7150\/ijbs.40834","article-title":"Transcription factor RREB1: from target genes towards biological functions","volume":"16","author":"Deng","year":"2020","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.ygeno.2026.111328_bb0215","article-title":"The fate of speckled protein 100 (Sp100) during herpesviruses infection","volume":"10","author":"Collados Rodr\u00edguez","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0220","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.24040","article-title":"Clinical impact of antibodies to Sp100 on a bacterial infection in patients with primary biliary cholangitis","volume":"35","author":"Himoto","year":"2021","journal-title":"J. Clin. Lab. Anal."},{"key":"10.1016\/j.ygeno.2026.111328_bb0225","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.immuni.2011.05.006","article-title":"Toll-like receptors and their crosstalk with other innate receptors in infection and immunity","volume":"34","author":"Kawai","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.ygeno.2026.111328_bb0230","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.immuni.2010.03.012","article-title":"Intracellular toll-like receptors","volume":"32","author":"Blasius","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.ygeno.2026.111328_bb0235","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/nrrheum.2016.61","article-title":"Toll-like receptors and chronic inflammation in rheumatic diseases: new developments","volume":"12","author":"Joosten","year":"2016","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0240","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1122586","article-title":"The role of NOD-like receptors in innate immunity","volume":"14","author":"Almeida-da-Silva","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0245","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cytogfr.2017.02.001","article-title":"Role of NOD- like receptors in glioma angiogenesis: insights into future therapeutic interventions","volume":"34","author":"Saxena","year":"2017","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.ygeno.2026.111328_bb0250","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/cr.2010.178","article-title":"Crosstalk of reactive oxygen species and NF-\u03baB signaling","volume":"21","author":"Morgan","year":"2011","journal-title":"Cell Res."},{"key":"10.1016\/j.ygeno.2026.111328_bb0255","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/s41573-019-0019-2","article-title":"AMP-activated protein kinase: the current landscape for drug development","volume":"18","author":"Steinberg","year":"2019","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ygeno.2026.111328_bb0260","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2013.00346","article-title":"Impact of MAPK pathway activation in BRAF(V600) melanoma on T cell and dendritic cell function","volume":"4","author":"Ott","year":"2013","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ygeno.2026.111328_bb0265","doi-asserted-by":"crossref","first-page":"3703","DOI":"10.1128\/IAI.00579-13","article-title":"The p38 MAPK and JNK pathways protect host cells against Clostridium perfringens beta-toxin","volume":"81","author":"Nagahama","year":"2013","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ygeno.2026.111328_bb0270","first-page":"213","article-title":"TNF-\u03b1 and IL-6: the link between immune and bone system","volume":"21","author":"Wang","year":"2020","journal-title":"Curr. Drug Targets"}],"container-title":["Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754326001369?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754326001369?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T08:35:06Z","timestamp":1793003706000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0888754326001369"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["S0888754326001369"],"URL":"https:\/\/doi.org\/10.1016\/j.ygeno.2026.111328","relation":{},"ISSN":["0888-7543"],"issn-type":[{"value":"0888-7543","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unveiling the long non-coding RNA profile of Aeromonas veronii-infected mouse abdominal macrophages","name":"articletitle","label":"Article Title"},{"value":"Genomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygeno.2026.111328","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"111328"}}