{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:34:07Z","timestamp":1791858847523,"version":"4.3.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1016\/j.ygyno.2004.08.040","type":"journal-article","created":{"date-parts":[[2004,12,19]],"date-time":"2004-12-19T07:26:17Z","timestamp":1103441177000},"page":"307-313","source":"Crossref","is-referenced-by-count":12,"title":["Twenty-five year outcome of sequential abdominal radiotherapy and melphalan:implications for future management of epithelial carcinoma of the ovary"],"prefix":"10.1016","volume":"96","author":[{"given":"Kathryn E.","family":"Dusenbery","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen E.","family":"Bellairs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger A.","family":"Potish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leo B.","family":"Twiggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew P.","family":"Boente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygyno.2004.08.040_bib1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3322\/canjclin.54.1.8","article-title":"Cancer statistics, 2004","volume":"53","author":"Jamal","year":"2004","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.ygyno.2004.08.040_bib2","series-title":"Clinical gynecologic oncology","first-page":"289","article-title":"Epithelial ovarian cancer","author":"DiSaia","year":"2002"},{"key":"10.1016\/j.ygyno.2004.08.040_bib3","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1148\/114.3.695","article-title":"Results of postoperative megavoltage radiotherapy of malignant surface epithelial surface tumors of the ovary","volume":"114","author":"Hintz","year":"1975","journal-title":"Radiology"},{"key":"10.1016\/j.ygyno.2004.08.040_bib4","first-page":"149","article-title":"Postoperative treatment of early cancer of the ovary: a random trial between postoperative irradiation and chemotherapy","volume":"42","author":"Smith","year":"1975","journal-title":"Natl. Cancer Inst. Monogr."},{"key":"10.1016\/j.ygyno.2004.08.040_bib5","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1200\/JCO.1987.5.6.897","article-title":"Analysis of postoperative radiation therapy in stage I through III epithelial ovarian carcinoma","volume":"5","author":"Fuller","year":"1987","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib6","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1200\/JCO.1985.3.7.901","article-title":"Postoperative radiation therapy for epithelial ovarian cancer: the curative role based on a 24-year experience","volume":"3","author":"Martinez","year":"1985","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib7","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1002\/1097-0142(19850501)55:9+<2285::AID-CNCR2820551436>3.0.CO;2-4","article-title":"Abdominopelvic radiotherapy in ovarian cancer: a 10-year experience","volume":"55","author":"Dembo","year":"1985","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2004.08.040_bib8","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0002-9378(83)90086-8","article-title":"Logistic models for prediction of enteric morbidity in the treatment of ovarian and cervical cancers","volume":"147","author":"Potish","year":"1983","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib9","doi-asserted-by":"crossref","first-page":"2754","DOI":"10.1002\/1097-0142(19800601)45:11<2754::AID-CNCR2820451109>3.0.CO;2-Q","article-title":"Sequential surgery, radiation therapy, and Alkeran in the management of epithelial carcinoma of the ovary","volume":"45","author":"Potish","year":"1980","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2004.08.040_bib10","first-page":"263","article-title":"Changes in definitions of clinical staging for carcinoma of the cervix and ovary: International Federation of Gynecologists and Oncologists","volume":"156","author":"Anon","year":"1987","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib11","article-title":"Histologic typing of ovarian tumors","volume":"vol. 9","author":"Serov","year":"1973"},{"key":"10.1016\/j.ygyno.2004.08.040_bib12","first-page":"376","article-title":"Carcinoma: grading and practical application","volume":"2","author":"Borders","year":"1926","journal-title":"Arch. Pathol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib13","doi-asserted-by":"crossref","first-page":"457","DOI":"10.2307\/2281868","article-title":"Nonparametric estimation from incomplete observation","volume":"53","author":"Kaplan","year":"1958","journal-title":"Am. Stat. Assoc. J."},{"key":"10.1016\/j.ygyno.2004.08.040_bib14","first-page":"163","article-title":"Evaluation of survival data and two new rank-order statistics arising in its consideration","volume":"50","author":"Mantel","year":"1966","journal-title":"Cancer Chemother. Rep."},{"key":"10.1016\/j.ygyno.2004.08.040_bib15","series-title":"Manual for staging of cancer","first-page":"11","article-title":"Reporting of cancer survival and end results","author":"Beahrs","year":"1988"},{"key":"10.1016\/j.ygyno.2004.08.040_bib16","unstructured":"Anon. Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0, DCTD, NCI, NIH, DHHS. 2003. (http:\/\/ctep.cancer.gov)."},{"key":"10.1016\/j.ygyno.2004.08.040_bib17","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1006\/gyno.1994.1347","article-title":"Chemotherapy in advanced ovarian carcinoma: current standards of care based on randomized trials","volume":"55","author":"Thigpen","year":"1994","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib18","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1056\/NEJM197707282970402","article-title":"Acute leukemia after alkylating-agent therapy of ovarian cancer","volume":"297","author":"Reimer","year":"1977","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ygyno.2004.08.040_bib19","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/S0360-3016(03)00510-8","article-title":"High-dose whole abdominal and pelvic irradiation for treatment of ovarian carcinoma: long-term toxicity and outcomes","volume":"57","author":"Firat","year":"2003","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib20","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1006\/gyno.1998.5184","article-title":"Consolidation radiotherapy after carboplatin-based chemotherapy in radically operated advanced ovarian cancer","volume":"72","author":"Pickel","year":"1999","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib21","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1046\/j.1525-1438.2003.13193.x","article-title":"Consolidation treatment of advanced (FIGO stage III) ovarian carcinoma in complete surgical remission after induction chemotherapy: a randomized, controlled, clinical trial comparing whole abdominal radiotherapy, chemotherapy, and no further treatment","volume":"13","author":"Sorbe","year":"2003","journal-title":"Int. J. Gynecol. Cancer"},{"key":"10.1016\/j.ygyno.2004.08.040_bib22","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1200\/JCO.1993.11.3.440","article-title":"A randomized clinical trial comparing single-agent carboplatinum followed by radiotherapy for advanced ovarian cancer. North Thames Ovary Group Study","volume":"11","author":"Lambert","year":"1993","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib23","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/S0936-6555(05)80210-9","article-title":"A randomized trial comparing whole abdominal radiotherapy with chemotherapy following cisplatinum cytoreduction in epithelial ovarian cancer. West Midlands Ovarian Cancer Group Trial II","volume":"2","author":"Lawton","year":"1990","journal-title":"Clin. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0090-8258(90)90080-5","article-title":"Chemotherapy versus radiotherapy in the management of ovarian cancer patients with pathological complete response or minimal residual disease at second look","volume":"38","author":"Bruzzone","year":"1990","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib25","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1177\/030089160108700407","article-title":"Consolidation radiation therapy following cytoreductive surgery, chemotherapy and second-look laparotomy for epithelial ovarian carcinoma: long-term follow-up","volume":"87","author":"Goldberg","year":"2001","journal-title":"Tumori"},{"key":"10.1016\/j.ygyno.2004.08.040_bib26","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1002\/cncr.2820710441","article-title":"Integrating radiation therapy into the management of ovarian cancer","volume":"71","author":"Thomas","year":"1993","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2004.08.040_bib27","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1093\/jnci\/61.5.1195","article-title":"Second primary neoplasms following ovarian cancer","volume":"61","author":"Reimer","year":"1978","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.ygyno.2004.08.040_bib28","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1023\/A:1008356806417","article-title":"Second primary malignancies following the treatment of early stage ovarian cancer: update of a study by the National Cancer Institute of Canada-Clinical Trials Group (NCIC-CTG)","volume":"11","author":"Dent","year":"2000","journal-title":"Ann. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib29","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0020-7292(00)00357-X","article-title":"Prior, synchronous, and secondary malignancies in women with ovarian cancer","volume":"73","author":"Kehoe","year":"2001","journal-title":"Int. J. Gynecol. Obstet."},{"key":"10.1016\/j.ygyno.2004.08.040_bib30","first-page":"995","article-title":"Second primary ovarian cancer among women previously diagnosed with cancer","volume":"10","author":"Hall","year":"2001","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"10.1016\/j.ygyno.2004.08.040_bib31","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1002\/1097-0142(19830401)51:7<1273::AID-CNCR2820510717>3.0.CO;2-T","article-title":"The use of intravenous phenylalanine mustard followed by supervoltage irradiation in the treatment of carcinoma of the ovary","volume":"51","author":"Nevin","year":"1983","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2004.08.040_bib32","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0360-3016(98)00066-2","article-title":"A randomized study of two doses of abdominopelvic radiation therapy for patients with optimally debulked stage I, II, and III ovarian cancer","volume":"41","author":"Fyles","year":"1998","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib33","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/S0360-3016(02)02921-8","article-title":"IMRT of large fields: whole-abdomen irradiation","volume":"54","author":"Hong","year":"2002","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib34","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/S0360-3016(03)00663-1","article-title":"Whole abdominopelvic radiotherapy (WAPRT) using intensity-modulated arc therapy (IMAT): first clinical experience","volume":"57","author":"Duthoy","year":"2003","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib35","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0167-8140(96)01859-2","article-title":"Respiration-induced motion of the kidneys in whole abdominal radiotherapy: implications for treatment planning and late toxicity","volume":"42","author":"Ahmad","year":"1997","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib36","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.ijrobp.2003.08.025","article-title":"Alterations in normal liver doses due to organ motion","volume":"57","author":"Rosu","year":"2003","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib37","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/S0360-3016(03)00521-2","article-title":"Intensity-modulated radiotherapy as a means of reducing dose to bone marrow in gynecologic patients receiving whole pelvic radiotherapy","volume":"57","author":"Lujan","year":"2003","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib38","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/S0360-3016(03)00409-7","article-title":"Does prone positioning reduce small bowel dose in pelvic radiation with intensity-modulated radiotherapy for gynecologic cancer?","volume":"57","author":"Adli","year":"2003","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib39","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/0360-3016(92)90779-H","article-title":"Complications of whole abdominal and pelvic radiotherapy following chemotherapy for advanced ovarian cancer","volume":"22","author":"Whelan","year":"1992","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.ygyno.2004.08.040_bib40","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1002\/cncr.10766","article-title":"Current concepts in radiation enteritis and implications for future clinical trials","volume":"95","author":"Nguyen","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2004.08.040_bib41","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1667\/RR3128","article-title":"Gene expression profile in human late radiation enteritis obtained by high-density cDNA array hybridization","volume":"161","author":"Vozenin-Brotons","year":"2004","journal-title":"Radiat. Res."},{"key":"10.1016\/j.ygyno.2004.08.040_bib42","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1080\/0955300031000150594","article-title":"\u2018In-field\u2019 and \u2018out-of-field\u2019 functional impairment during subacute and chronic phases of experimental radiation enteropathy in the rat","volume":"79","author":"Francois","year":"2003","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib43","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1097\/01.COC.0000027269.06091.E9","article-title":"Melphalan for the treatment of patients with recurrent epithelial ovarian cancer","volume":"26","author":"Davis-Perry","year":"2003","journal-title":"Am. J. Clin. Oncol."},{"key":"10.1016\/j.ygyno.2004.08.040_bib44","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1038\/sj.bjc.6601044","article-title":"Oral melphalan as a treatment for platinum-resistant ovarian cancer","volume":"88","author":"Hasan","year":"2003","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.ygyno.2004.08.040_bib45","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1200\/JCO.2003.02.153","article-title":"Phase III trial of carbolplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a gynecologic oncology group study","volume":"21","author":"Ozols","year":"2003","journal-title":"J. Clin. Oncol."}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825804007000?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825804007000?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T16:56:33Z","timestamp":1548867393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825804007000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":45,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0090825804007000"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2004.08.040","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}