{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:46:33Z","timestamp":1791107193940,"version":"4.1.0"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1016\/j.ygyno.2004.08.047","type":"journal-article","created":{"date-parts":[[2004,12,13]],"date-time":"2004-12-13T17:57:31Z","timestamp":1102960651000},"page":"77-83","source":"Crossref","is-referenced-by-count":62,"title":["Clinical applications of microarray technology: creatine kinase B is an up-regulated gene in epithelial ovarian cancer and shows promise as a serum marker"],"prefix":"10.1016","volume":"96","author":[{"given":"Heather G.","family":"Huddleston","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwong-kwok","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Welch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross S.","family":"Berkowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel C.","family":"Mok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygyno.2004.08.047_bib1","series-title":"Cancer facts and figures","author":"American Cancer Society","year":"2003"},{"key":"10.1016\/j.ygyno.2004.08.047_bib2","series-title":"SEER Cancer Statistics Review 1973\u20131995","author":"Ries","year":"1998"},{"issue":"Suppl. 1","key":"10.1016\/j.ygyno.2004.08.047_bib3","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/4434","article-title":"Expression profiling using cDNA microarrays","volume":"21","author":"Duggan","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ygyno.2004.08.047_bib4","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1126\/science.270.5235.467","article-title":"Quantitative monitoring of gene expression patterns with a complementary DNA microarray","volume":"270","author":"Schena","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.ygyno.2004.08.047_bib5","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1093\/jnci\/93.19.1458","article-title":"Prostasin is an upregulated gene in epithelial ovarian cancer with potential as a serum marker identified through microarray technology","volume":"93","author":"Mok","year":"2001","journal-title":"J. Natl. Cancer. Inst."},{"key":"10.1016\/j.ygyno.2004.08.047_bib6","first-page":"5656","article-title":"In vivo gene expression profile analysis of human breast cancer progession","volume":"595","author":"Sgroi","year":"1999","journal-title":"Cancer Res."},{"key":"10.1016\/j.ygyno.2004.08.047_bib7","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1006\/excr.1995.1184","article-title":"Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORF)","volume":"218","author":"Tsao","year":"1995","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.ygyno.2004.08.047_bib8","series-title":"Microarrays in cancer research","first-page":"127","article-title":"Gene expression analysis of ovarian cancer cells by cDNA microarray","author":"Wong","year":"2002"},{"key":"10.1016\/j.ygyno.2004.08.047_bib9","doi-asserted-by":"crossref","first-page":"670","DOI":"10.2144\/01303dd05","article-title":"Identification of differentially expressed genes from ovarian cancer cells by micromax cDNA microarray system","volume":"30","author":"Wong","year":"2001","journal-title":"BioTechniques"},{"key":"10.1016\/j.ygyno.2004.08.047_bib10","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.1001\/jama.287.13.1671","article-title":"Osteopontin as a potential diagnostic biomarker for ovarian cancer","volume":"287","author":"Kim","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.ygyno.2004.08.047_bib11","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0272-2712(18)30800-X","article-title":"Creatine kinase isoenzymes","volume":"5","author":"Lott","year":"1986","journal-title":"Clin. Lab. Med."},{"key":"10.1016\/j.ygyno.2004.08.047_bib12","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1002\/ana.410030108","article-title":"Creatine kinase BB isoenzyme levels by radioimmunoassay in patients with neurological disease","volume":"3","author":"Bell","year":"1978","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ygyno.2004.08.047_bib13","first-page":"333","article-title":"Significance of creatine-kinase (CKBB) in metastatic cancer of the prostate","volume":"9","author":"Forman","year":"1979","journal-title":"Ann. Clin. Lab. Sci."},{"key":"10.1016\/j.ygyno.2004.08.047_bib14","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1161\/01.CIR.47.2.263","article-title":"The importance of identification of the myocardial-specific isoencyme of creatine phosphokinase (MB form) in the diagnosis of acute myocardial infarction","volume":"47","author":"Wagner","year":"1973","journal-title":"Circulation"},{"key":"10.1016\/j.ygyno.2004.08.047_bib15","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1210\/mend-4-7-1000","article-title":"Estrogen regulation of creatine kinase-B in the rat uterus","volume":"4","author":"Pentecost","year":"1990","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.ygyno.2004.08.047_bib16","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1210\/me.6.2.231","article-title":"Delineation of sites mediating estrogen regulation of the rat creatine kinase B gene","volume":"6","author":"Wu-Peng","year":"1992","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.ygyno.2004.08.047_bib17","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/0009-9120(95)00010-7","article-title":"Quantification of creatine kinase BB isoenzyme in tumor cytosols and serum with an ultrasensitive time-resolved immunofluorometric technique","volume":"28","author":"Zarghami","year":"1995","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.ygyno.2004.08.047_bib18","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/bjc.1996.66","article-title":"Creatine kinase BB isoenzyme levels in tumour cytosols and survival of breast cancer patients","volume":"73","author":"Zarghami","year":"1996","journal-title":"Br. J. Cancer"}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825804006481?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825804006481?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,31]],"date-time":"2019-01-31T13:00:39Z","timestamp":1548939639000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825804006481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S0090825804006481"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2004.08.047","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}