{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T01:45:34Z","timestamp":1780105534439,"version":"3.54.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1016\/j.ygyno.2007.03.010","type":"journal-article","created":{"date-parts":[[2007,4,27]],"date-time":"2007-04-27T11:13:42Z","timestamp":1177672422000},"page":"142-146","source":"Crossref","is-referenced-by-count":28,"title":["Recurrent gestational trophoblastic disease after hCG normalization following hydatidiform mole in The Netherlands"],"prefix":"10.1016","volume":"106","author":[{"given":"Linda G.W.","family":"Kerkmeijer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabien","family":"Wielsma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon F.A.G.","family":"Massuger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred C.G.J.","family":"Sweep","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris M.G.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygyno.2007.03.010_bib1","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/0029-7844(95)00268-V","article-title":"The changing clinical presentation of complete molar pregnancy","volume":"86","author":"Soto-Wright","year":"1995","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib2","first-page":"414","article-title":"Sonographic diagnosis of partial hydatidiform mole","volume":"73","author":"Fine","year":"1989","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib3","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1006\/gyno.2000.5839","article-title":"Gestational trophoblastic disease: a study of mode of evacuation and subsequent need for treatment with chemotherapy","volume":"78","author":"Tidy","year":"2000","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib4","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1054\/cdip.2002.0144","article-title":"Diagnosis of gestational trophoblastic disease in early pregnancy","volume":"8","author":"Sebire","year":"2002","journal-title":"Curr. Diagn. Pathol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib5","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1046\/j.1365-2559.1996.247295.x","article-title":"A clinical, histopathological and flow cytometric study of 149 complete moles, 146 partial moles and 107 non-molar hydropic abortions","volume":"28","author":"Paradinas","year":"1996","journal-title":"Histopathology"},{"key":"10.1016\/j.ygyno.2007.03.010_bib6","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1053\/hupa.2002.129421","article-title":"Immunohistochemical characterization of p57kip2 expression in early hydatidiform moles","volume":"33","author":"Fukunaga","year":"2002","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib7","first-page":"155","article-title":"Advances in the epidemiology of gestational trophoblastic disease","volume":"39","author":"Palmer","year":"1994","journal-title":"J. Reprod. Med."},{"key":"10.1016\/j.ygyno.2007.03.010_bib8","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0140-6736(00)02432-6","article-title":"Choriocarcinoma and partial hydatidiform moles","volume":"356","author":"Seckl","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.ygyno.2007.03.010_bib9","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1097\/01.AOG.0000136099.21216.45","article-title":"Low risk of relapse after achieving undetectable hCG levels in women with complete molar pregnancy","volume":"104","author":"Wolfberg","year":"2004","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib10","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/S0029-7844(03)00009-7","article-title":"Human chorionic gonadotropin follow-up in patients with molar pregnancy: a time for reevaluation","volume":"101","author":"Feltmate","year":"2003","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib11","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1200\/JCO.2002.07.166","article-title":"Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000","volume":"20","author":"McNeish","year":"2002","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib12","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1200\/JCO.1997.15.7.2636","article-title":"EMA\/CO for high-risk gestational trophoblastic tumors: results from a cohort of 272 patients","volume":"15","author":"Bower","year":"1997","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib13","first-page":"1","article-title":"Quantitative chorionic gonadotropin: prognostic value in hydatidiform mole and chorionepithelioma","volume":"9","author":"Delfs","year":"1957","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0140-6736(86)90179-0","article-title":"Hydatidiform mole in England and Wales 1973\u20131983","volume":"2","author":"Bagshawe","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.ygyno.2007.03.010_bib15","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.ygyno.2005.01.015","article-title":"The impact of molar pregnancy on psychological symptomatology, sexual function, and quality of life","volume":"97","author":"Petersen","year":"2005","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib16","first-page":"163","article-title":"Psychological, social and sexual effects of gestational trophoblastic disease on patients and their partners","volume":"39","author":"Wenzel","year":"1994","journal-title":"J. Reprod. Med."},{"key":"10.1016\/j.ygyno.2007.03.010_bib17","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1016\/j.ajog.2004.12.080","article-title":"Duration of human chorionic gonadotropin surveillance for partial hydatidiform moles","volume":"192","author":"Lavie","year":"2005","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib18","first-page":"95","article-title":"How long should patients be followed after molar pregnancy? Analysis of serum hCG follow-up data","volume":"112","author":"Batorfi","year":"2004","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib19","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1479-828X.2006.00539.x","article-title":"Persistent trophoblast disease following partial molar pregnancy","volume":"46","author":"Wielsma","year":"2006","journal-title":"Aust. N. Z. J. Obstet. Gynaecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib20","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1479-828X.2006.00538.x","article-title":"Guidelines following hydatidiform mole: a reappraisal","volume":"46","author":"Kerkmeijer","year":"2006","journal-title":"Aust. N.Z.J. Obstet. Gynaecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib21","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/01.AOG.0000227754.12848.4e","article-title":"Low risk of relapse after achieving undetectable hCG levels in women with partial molar pregnancy","volume":"108","author":"Wolfberg","year":"2006","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib22","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.ygyno.2004.11.011","article-title":"Relapse rate of patients with low-risk gestational trophoblastic tumor initially treated with single-agent chemotherapy","volume":"96","author":"Matsui","year":"2005","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib23","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/sj.bjc.6600041","article-title":"The effect of early pregnancy following chemotherapy on disease relapse and foetal outcome in women treated for gestational trophoblastic tumours","volume":"86","author":"Blagden","year":"2002","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.ygyno.2007.03.010_bib24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0020-7292(00)90001-8","article-title":"Figo staging classifications and clinical practice guidelines in the management of gynecologic cancers","volume":"70","author":"Benedet","year":"2000","journal-title":"Int. J. Gynecol. Obstet."},{"key":"10.1016\/j.ygyno.2007.03.010_bib25","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0002-9378(12)90820-0","article-title":"Identification of patients with persistent trophoblastic disease by means of a normal human chorionic gonadotropin regression curve","volume":"168","author":"Yedema","year":"1993","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.ygyno.2007.03.010_bib26","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1177\/000456328502200305","article-title":"Comparison of the analytical characteristics and clinical usefulness in tumour monitoring of fifteen hCG (-beta) immunoassay kits","volume":"22","author":"Thomas","year":"1985","journal-title":"Ann. Clin. Biochem."}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825807002028?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825807002028?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T15:02:35Z","timestamp":1556377355000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825807002028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["S0090825807002028"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2007.03.010","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2007,7]]}}}