{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:16:59Z","timestamp":1791314219764,"version":"4.3.1"},"reference-count":63,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.ygyno.2011.12.435","type":"journal-article","created":{"date-parts":[[2011,12,20]],"date-time":"2011-12-20T15:23:18Z","timestamp":1324394598000},"page":"417-425","source":"Crossref","is-referenced-by-count":124,"title":["A randomized phase III clinical trial of a combined treatment for cachexia in patients with gynecological cancers: Evaluating the impact on metabolic and inflammatory profiles and quality of life"],"prefix":"10.1016","volume":"124","author":[{"given":"Antonio","family":"Macci\u00f2","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clelia","family":"Madeddu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Gramignano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Mulas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Floris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Sanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Chiara","family":"Cau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filomena","family":"Panzone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Mantovani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygyno.2011.12.435_bb0005","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3322\/caac.20073","article-title":"Cancer statistics, 2010","volume":"60","author":"Jemal","year":"2010","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0010","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1097\/01.NCC.0000290809.61206.ef","article-title":"Symptom clusters and quality of life in survivors of ovarian cancer","volume":"30","author":"Fox","year":"2007","journal-title":"Cancer Nurs"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0015","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.ygyno.2010.05.014","article-title":"A review of issues surrounding quality of life among women with ovarian cancer","volume":"119","author":"Arriba","year":"2010","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0020","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1615\/CritRevOncog.v9.i2.10","article-title":"Cytokine involvement in cancer anorexia\/cachexia: role of megestrol acetate and medroxyprogesterone acetate on cytokine downregulation and improvement of clinical symptoms","volume":"9","author":"Mantovani","year":"1998","journal-title":"Crit Rev Oncog"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0025","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1006\/gyno.1998.4974","article-title":"High serum levels of soluble IL-2 receptor, cytokines, and C reactive protein correlate with impairment of T cell response in patients with advanced epithelial ovarian cancer","volume":"69","author":"Macci\u00f2","year":"1998","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0030","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/ijc.10143","article-title":"Quantitative evaluation of oxidative stress, chronic inflammatory indices and leptin in cancer patients: correlation with stage and performance status","volume":"98","author":"Mantovani","year":"2002","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0035","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/s001090000137","article-title":"Serum levels of leptin and proinflammatory cytokines in patients with advanced-stage cancer at different sites","volume":"78","author":"Mantovani","year":"2000","journal-title":"J Mol Med (Berl)"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0040","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s001090100234","article-title":"Serum values of proinflammatory cytokines are inversely correlated with serum leptin levels in patients with advanced stage cancer at different sites","volume":"79","author":"Mantovani","year":"2001","journal-title":"J Mol Med (Berl)"},{"issue":"9B","key":"10.1016\/j.ygyno.2011.12.435_bb0045","doi-asserted-by":"crossref","first-page":"3951","DOI":"10.1111\/j.1582-4934.2008.00408.x","article-title":"Interleukin-6 and leptin as markers of energy metabolic changes in advanced ovarian cancer patients","volume":"13","author":"Macci\u00f2","year":"2009","journal-title":"J Cell Mol Med"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0050","doi-asserted-by":"crossref","first-page":"499","DOI":"10.2165\/00003495-200161040-00004","article-title":"Managing cancer-related anorexia\/cachexia","volume":"61","author":"Mantovani","year":"2001","journal-title":"Drugs"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0055","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1158\/1055-9965.1651.13.10","article-title":"Cancer-related anorexia\/cachexia syndrome and oxidative stress: an innovative approach beyond current treatment","volume":"13","author":"Mantovani","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0060","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1158\/1055-9965.EPI-05-0538","article-title":"A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia\/cachexia and oxidative stress","volume":"15","author":"Mantovani","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0065","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/BF02592554","article-title":"Megestrol acetate in neoplastic anorexia\/cachexia: clinical evaluation and comparison with cytokine levels in patients with head and neck carcinoma treated with neoadjuvant chemotherapy","volume":"25","author":"Mantovani","year":"1995","journal-title":"Int J Clin Lab Res"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0070","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1023\/A:1008291825695","article-title":"Improved quality of life with megestrol acetate in patients with endocrine-insensitive advanced cancer: a randomised placebo-controlled trial. Australasian Megestrol Acetate Cooperative Study Group","volume":"8","author":"Beller","year":"1997","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0075","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1002\/1097-0142(19900915)66:6<1279::AID-CNCR2820660630>3.0.CO;2-R","article-title":"A controlled trial of megestrol acetate on appetite, caloric intake, nutritional status, and other symptoms in patients with advanced cancer","volume":"66","author":"Bruera","year":"1990","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0080","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1093\/jnci\/82.13.1127","article-title":"Controlled trial of megestrol acetate for the treatment of cancer anorexia and cachexia","volume":"82","author":"Loprinzi","year":"1990","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0085","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1002\/cncr.2820690532","article-title":"Megestrol acetate in cancer anorexia and weight loss","volume":"69","author":"Tchekmedyian","year":"1992","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0090","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1200\/JCO.1993.11.4.762","article-title":"Phase III evaluation of four doses of megestrol acetate as therapy for patients with cancer anorexia and\/or cachexia","volume":"11","author":"Loprinzi","year":"1993","journal-title":"J Clin Oncol"},{"issue":"2","key":"10.1016\/j.ygyno.2011.12.435_bb0095","first-page":"CD004310","article-title":"Megestrol acetate for the treatment of anorexia\u2013cachexia syndrome","author":"Berenstein","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0100","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/(SICI)1097-0142(19980201)82:3<553::AID-CNCR18>3.0.CO;2-0","article-title":"Effects of medroxyprogesterone acetate on food intake, body composition, and resting energy expenditure in patients with advanced, nonhormone-sensitive cancer: a randomized, placebo-controlled trial","volume":"82","author":"Simons","year":"1998","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0105","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3322\/canjclin.52.2.72","article-title":"Cancer anorexia\u2013cachexia syndrome: current issues in research and management","volume":"52","author":"Inui","year":"2002","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0110","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1080\/10715760303849","article-title":"The impact of different antioxidant agents alone or in combination on reactive oxygen species, antioxidant enzymes and cytokines in a series of advanced cancer patients at different sites: correlation with disease progression","volume":"37","author":"Mantovani","year":"2003","journal-title":"Free Radic Res"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0115","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1007\/s00109-003-0476-1","article-title":"Antioxidant agents are effective in inducing lymphocyte progression through cell cycle in advanced cancer patients: assessment of the most important laboratory indexes of cachexia and oxidative stress","volume":"81","author":"Mantovani","year":"2003","journal-title":"J Mol Med"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0120","first-page":"887","article-title":"Phase II study of subcutaneously administered interleukin-2 in combination with medroxyprogesterone acetate and antioxidant agents as maintenance treatment in advanced cancer responders to previous chemotherapy","volume":"9","author":"Mantovani","year":"2002","journal-title":"Oncol Rep"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0125","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/sj.mp.4000805","article-title":"Acetyl-l-carnitine physical\u2013chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression","volume":"5","author":"Pettegrew","year":"2000","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0130","first-page":"345","article-title":"l-carnitine: therapeutic applications of a conditionally-essential amino acid","volume":"3","author":"Kelly","year":"1998","journal-title":"Altern Med Rev"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0135","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.nut.2005.06.003","article-title":"Efficacy of l-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy","volume":"22","author":"Gramignano","year":"2006","journal-title":"Nutrition"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0140","first-page":"505","article-title":"Evidence that long-term COX-treatment improves energy homeostasis and body composition in cancer patients with progressive cachexia","volume":"24","author":"Lundholm","year":"2004","journal-title":"Int J Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0145","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/hed.20662","article-title":"Results of a pilot study of the effects of celecoxib on cancer cachexia in patients with cancer of the head, neck, and gastrointestinal tract","volume":"30","author":"Lai","year":"2008","journal-title":"Head Neck"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0150","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0155","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1007\/s12603-009-0082-1","article-title":"Usage of megestrol acetate in the treatment of anorexia\u2013cachexia syndrome in the elderly","volume":"13","author":"Yeh","year":"2009","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0160","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1517\/14656560902960162","article-title":"Medroxyprogesterone acetate in the management of cancer cachexia","volume":"10","author":"Madeddu","year":"2009","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0165","first-page":"764","article-title":"Megestrol acetate therapy in geriatric patients: case reviews and associated deep vein thrombosis","volume":"18","author":"Marshall","year":"2003","journal-title":"Consult Pharm"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0170","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/S1470-2045(09)70232-3","article-title":"Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: a randomised, placebo-controlled, double-blind study","volume":"10","author":"Agnelli","year":"2009","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0175","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1634\/theoncologist.2010-0020","article-title":"Efficacy and safety of oral lactoferrin supplementation in combination with rHuEPO-beta for the treatment of anemia in advanced cancer patients undergoing chemotherapy: open-label, randomized controlled study","volume":"15","author":"Macci\u00f2","year":"2010","journal-title":"Oncologist"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0180","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s00520-005-0830-7","article-title":"Fatigue in gynaecological cancer patients: a pilot study","volume":"14","author":"Prue","year":"2006","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0185","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1007\/s00520-010-0969-8","article-title":"Toxicity and quality of life outcomes in ovarian cancer patients participating in randomized controlled trials","volume":"19","author":"Greimel","year":"2011","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0190","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ygyno.2007.08.088","article-title":"The prognostic effects of performance status and quality of life scores on progression-free survival and overall survival in advanced ovarian cancer","volume":"108","author":"Carey","year":"2008","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0195","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","article-title":"Toxicity and response criteria of the Eastern Cooperative Oncology Group","volume":"5","author":"Oken","year":"1982","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0200","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1182\/blood-2005-01-0160","article-title":"Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: role of inflammation in cancer-related anemia","volume":"106","author":"Macci\u00f2","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0205","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1017\/S0029665108007131","article-title":"An inflammation-based prognostic score and its role in the nutrition-based management of patients with cancer","volume":"67","author":"McMillan","year":"2008","journal-title":"Proc Nutr Soc"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0210","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1111\/IGC.0b013e3181e64bb1","article-title":"The inflammation-based Glasgow Prognostic Score predicts survival in patients with cervical cancer","volume":"20","author":"Polterauer","year":"2010","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0215","author":"National Cancer Institute"},{"issue":"2 Suppl. 6","key":"10.1016\/j.ygyno.2011.12.435_bb0220","first-page":"45","article-title":"Cytokine activity in cancer-related anorexia\/cachexia: role of megestrol acetate and medroxyprogesterone acetate","volume":"25","author":"Mantovani","year":"1998","journal-title":"Semin Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0225","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/SPC.0b013e3283311d09","article-title":"The role of cytokines in cancer cachexia","volume":"3","author":"Argil\u00e9s","year":"2009","journal-title":"Curr Opin Support Palliat Care"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0230","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1111\/j.1365-2796.2010.02218.x","article-title":"Energy regulation and neuroendocrine-immune control in chronic inflammatory diseases","volume":"267","author":"Straub","year":"2010","journal-title":"J Intern Med"},{"issue":"Suppl. 1","key":"10.1016\/j.ygyno.2011.12.435_bb0235","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1016\/j.ejphar.2011.07.007","article-title":"Anti-inflammatory therapies in cancer cachexia","volume":"668","author":"Argil\u00e9s","year":"2011","journal-title":"Eur J Pharmacol"},{"issue":"2B","key":"10.1016\/j.ygyno.2011.12.435_bb0240","first-page":"735","article-title":"Serum interleukin-6 levels in uterine malignancies. Preliminary data","volume":"14","author":"Ferdeghini","year":"1994","journal-title":"Anticancer Res"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0245","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1002\/ijc.2910570305","article-title":"Interleukin-6 serum levels in patients with gynecological tumors","volume":"57","author":"Scambia","year":"1994","journal-title":"Int J Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0250","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s11010-010-0437-2","article-title":"Oxidant\/anti-oxidant dynamics in patients with advanced cervical cancer: correlation with treatment response","volume":"341","author":"Sharma","year":"2010","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0255","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1097\/01.AOG.0000292085.50987.f2","article-title":"Association of elevated C-reactive protein levels with an impaired prognosis in patients with surgically treated endometrial cancer","volume":"110","author":"Schmid","year":"2007","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0260","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.ygyno.2007.06.001","article-title":"C-reactive protein is a prognostic parameter in patients with cervical cancer","volume":"107","author":"Polterauer","year":"2007","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0265","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ejca.2007.11.011","article-title":"Evaluation of an inflammation-based prognostic score in patients with advanced ovarian cancer","volume":"44","author":"Sharma","year":"2008","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0270","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.ejogrb.2009.12.027","article-title":"The inflammation-based modified Glasgow Prognostic Score in patients with vulvar cancer","volume":"149","author":"Hefler-Frischmuth","year":"2010","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0275","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/cncr.21147","article-title":"Psychosocial factors and interleukin-6 among women with advanced ovarian cancer","volume":"104","author":"Costanzo","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpainsymman.2010.10.261","article-title":"Pain, depression, and fatigue as a symptom cluster in advanced cancer","volume":"42","author":"Laird","year":"2011","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00520-009-0722-3","article-title":"Cancer cachexia: medical management","volume":"18","author":"Mantovani","year":"2010","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0290","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1634\/theoncologist.2010-0019","article-title":"More is better: a multimodality approach to cancer cachexia","volume":"15","author":"Del Fabbro","year":"2010","journal-title":"Oncologist"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0295","doi-asserted-by":"crossref","first-page":"S143","DOI":"10.2337\/diabetes.53.2007.S143","article-title":"Update on adipocyte hormones: regulation of energy balance and carbohydrate\/lipid metabolism","volume":"53","author":"Havel","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0300","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1097\/MPH.0b013e3181864a5e","article-title":"The effect of cyproheptadine hydrochloride (periactin) and megestrol acetate (megace) on weight in children with cancer\/treatment-related cachexia","volume":"30","author":"Couluris","year":"2008","journal-title":"Pediatr Hematol Oncol"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0305","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.jrn.2004.10.006","article-title":"Megestrol acetate in a moderate dose for the treatment of malnutrition\u2013inflammation complex in maintenance dialysis patients","volume":"15","author":"Rammohan","year":"2005","journal-title":"J Ren Nutr"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0310","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1093\/gerona\/58.2.M165","article-title":"Effects of testosterone replacement and\/or resistance training on interleukin-6, tumor necrosis factor alpha, and leptin in elderly men ingesting megestrol acetate: a randomized controlled trial","volume":"58","author":"Lambert","year":"2003","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.ygyno.2011.12.435_bb0315","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1089\/jpm.2011.0098","article-title":"Clinical outcomes and contributors to weight loss in a cancer cachexia clinic","volume":"14","author":"Del Fabbro","year":"2011","journal-title":"J Palliat Med"}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825811014302?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825811014302?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,6,11]],"date-time":"2023-06-11T23:43:53Z","timestamp":1686527033000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825811014302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":63,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S0090825811014302"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2011.12.435","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}