{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T23:45:31Z","timestamp":1778888731503,"version":"3.51.4"},"reference-count":12,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.ygyno.2012.07.118","type":"journal-article","created":{"date-parts":[[2012,8,4]],"date-time":"2012-08-04T01:04:02Z","timestamp":1344042242000},"page":"312-315","source":"Crossref","is-referenced-by-count":99,"title":["Vulvar intraepithelial neoplasia (VIN 2\/3): Comparing clinical outcomes and evaluating risk factors for recurrence"],"prefix":"10.1016","volume":"127","author":[{"given":"J.J.","family":"Wallbillich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.E.","family":"Rhodes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"Milbourne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.F.","family":"Munsell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Frumovitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.L.","family":"Trimble","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.M.","family":"Schmeler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.ygyno.2012.07.118_bb0005","first-page":"613","article-title":"Trends in vulvar neoplasia. Increasing incidence of vulvar intraepithelial neoplasia and squamous cell carcinoma of the vulva in young women","volume":"45","author":"Joura","year":"2000","journal-title":"J Reprod Med"},{"issue":"5","key":"10.1016\/j.ygyno.2012.07.118_bb0010","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1097\/01.AOG.0000210268.57527.a1","article-title":"Trends in the incidence of invasive and in situ vulvar carcinoma","volume":"107","author":"Judson","year":"2006","journal-title":"Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.ygyno.2012.07.118_bb0015","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1097\/01.AOG.0000187301.76283.7f","article-title":"Vulvar intraepithelial neoplasia: aspects of the natural history and outcome in 405 women","volume":"106","author":"Jones","year":"2005","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ygyno.2012.07.118_bb0020","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.ygyno.2005.02.012","article-title":"Is the assumed natural history of vulvar intraepithelial neoplasia III based on enough evidence? A systematic review of 3322 published patients","volume":"97","author":"van Seters","year":"2005","journal-title":"Gynecol Oncol"},{"issue":"2","key":"10.1016\/j.ygyno.2012.07.118_bb0070","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1006\/gyno.1995.1046","article-title":"Vulvar intraepithelial neoplasia III: a viral disease of undetermined progressive potential","volume":"56","author":"H\u00f8rding","year":"1995","journal-title":"Gynecol Oncol"},{"issue":"3","key":"10.1016\/j.ygyno.2012.07.118_bb0035","first-page":"140","article-title":"Risk factors for recurrent VIN. Role of multifocality and grade of disease","volume":"42","author":"K\u00fcppers","year":"1997","journal-title":"J Reprod Med"},{"issue":"6","key":"10.1016\/j.ygyno.2012.07.118_bb0040","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/S0029-7844(98)00350-0","article-title":"Vulvar intraepithelial neoplasia III: occult cancer and the impact of margin status on recurrence","volume":"92","author":"Modesitt","year":"1998","journal-title":"Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.ygyno.2012.07.118_bb0075","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1097\/01.AOG.0000258783.49564.5c","article-title":"Surgical treatments for vulvar and vaginal dysplasia: a randomized controlled trial","volume":"109","author":"von Gruenigen","year":"2007","journal-title":"Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.ygyno.2012.07.118_bb0055","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/j.1471-0528.1996.tb09771.x","article-title":"Vulvar intraepithelial neoplasia: long term follow up of treated and untreated women","volume":"103","author":"Herod","year":"1996","journal-title":"Br J Obstet Gynaecol"},{"issue":"1","key":"10.1016\/j.ygyno.2012.07.118_bb0080","first-page":"CD007928","article-title":"Surgical interventions for high grade vulval intraepithelial neoplasia","author":"Kaushik","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1016\/j.ygyno.2012.07.118_bb0065","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.ygyno.2005.08.012","article-title":"Evaluation of different treatment modalities for vulvar intraepithelial neoplasia (VIN): CO(2) laser vaporization, photodynamic therapy, excision and vulvectomy","volume":"100","author":"Hillemanns","year":"2006","journal-title":"Gynecol Oncol"},{"issue":"4","key":"10.1016\/j.ygyno.2012.07.118_bb0085","first-page":"CD007924","article-title":"Medical interventions for high grade vulval intraepithelial neoplasia","author":"Pepas","year":"2011","journal-title":"Cochrane Database Syst Rev"}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825812006440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825812006440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,21]],"date-time":"2018-11-21T12:58:28Z","timestamp":1542805108000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825812006440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,11]]}},"alternative-id":["S0090825812006440"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2012.07.118","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}