{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T12:27:54Z","timestamp":1782390474649,"version":"3.54.5"},"reference-count":51,"publisher":"Elsevier BV","issue":"3","content-domain":{"domain":["gynecologiconcology-online.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1016\/j.ygyno.2014.03.569","type":"journal-article","created":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T02:16:56Z","timestamp":1396318616000},"page":"499-505","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"title":["Intra-operative frozen section results reliably predict final pathology in endometrial cancer"],"prefix":"10.1016","volume":"133","author":[{"given":"Jean-Marie","family":"Stephan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Samuelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yenna","family":"Chin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Bender","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry D.","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Button","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Goodheart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ygyno.2014.03.569_bb0005","doi-asserted-by":"crossref","first-page":"212","DOI":"10.3322\/caac.20121","article-title":"Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths","volume":"61","author":"Siegel","year":"2011","journal-title":"CA Cancer J Clin"},{"issue":"Suppl. 1","key":"10.1016\/j.ygyno.2014.03.569_bb0010","doi-asserted-by":"crossref","first-page":"S105","DOI":"10.1016\/S0020-7292(06)60031-3","article-title":"Carcinoma of the corpus uteri. FIGO 26th Annual Report on the results of treatment in gynecological cancer","volume":"95","author":"Creasman","year":"2006","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0015","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0140-6736(08)61766-3","article-title":"Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study","volume":"373","author":"Kitchener","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0020","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1093\/jnci\/djn397","article-title":"Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial","volume":"100","author":"Benedetti Panici","year":"2008","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0025","doi-asserted-by":"crossref","first-page":"181963","DOI":"10.1155\/2010\/181963","article-title":"Controversies in surgical staging of endometrial cancer","volume":"2010","author":"Seracchioli","year":"2010","journal-title":"Obstet Gynecol Int"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0030","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1002\/1097-0142(19901015)60:8+<2035::AID-CNCR2820601515>3.0.CO;2-8","article-title":"Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group study","volume":"60","author":"Creasman","year":"1987","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0035","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.ygyno.2012.08.024","article-title":"A prospective assessment of the reliability of frozen section to direct intraoperative decision making in endometrial cancer","volume":"127","author":"Kumar","year":"2012","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0040","first-page":"798","article-title":"Accuracy of frozen section for the operative management of endometrial cancer","volume":"108","author":"Quinlivan","year":"2001","journal-title":"BJOG"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0045","first-page":"435","article-title":"Accuracy of frozen section diagnosis at surgery in pre-malignant and malignant lesions of the endometrium","volume":"29","author":"Attard Montalto","year":"2008","journal-title":"Eur J Gynaecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0050","doi-asserted-by":"crossref","first-page":"e21912","DOI":"10.1371\/journal.pone.0021912","article-title":"The role of frozen section in surgical staging of low risk endometrial cancer","volume":"6","author":"Kumar","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0055","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.jamcollsurg.2004.05.258","article-title":"Frozen section analyses as predictors of lymphatic spread in patients with early-stage uterine cancer","volume":"199","author":"Frumovitz","year":"2004","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0060","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ygyno.2008.01.023","article-title":"Prospective assessment of lymphatic dissemination in endometrial cancer: a paradigm shift in surgical staging","volume":"109","author":"Mariani","year":"2008","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0065","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/0029-7844(95)00105-Z","article-title":"Comparison of D&C and office endometrial biopsy in predicting final histopathologic grade in endometrial cancer","volume":"86","author":"Larson","year":"1995","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0070","first-page":"612","article-title":"Accuracy of office and operating room curettage in the grading of endometrial carcinoma","volume":"71","author":"Daniel","year":"1988","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0075","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/0090-8258(91)90346-7","article-title":"The ability to evaluate prognostic variables on frozen section in hysterectomies performed for endometrial carcinoma","volume":"42","author":"Noumoff","year":"1991","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0080","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0090-8258(90)90306-6","article-title":"Intraoperative frozen section diagnosis of depth of myometrial invasion in endometrial adenocarcinoma","volume":"37","author":"Fanning","year":"1990","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0085","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0002-9378(11)91420-3","article-title":"Evaluation of pretreatment transvaginal ultrasonography in the management of patients with endometrial carcinoma","volume":"167","author":"Shipley","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0090","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1111\/j.1471-0528.1994.tb13157.x","article-title":"Serum CA 125 levels and sonography in the pre-operative assessment of myometrial invasion of endometrial cancer","volume":"101","author":"Lehtovirta","year":"1994","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0095","doi-asserted-by":"crossref","first-page":"343","DOI":"10.3109\/00016349409015776","article-title":"Transvaginal sonography of myometrial invasion depth in endometrial cancer","volume":"73","author":"Prompeler","year":"1994","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0100","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1046\/j.1469-0705.1996.07060443.x","article-title":"Transvaginal sonography vs. hysteroscopy in the preoperative staging of endometrial carcinoma","volume":"7","author":"Gabrielli","year":"1996","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0105","first-page":"128","article-title":"The value of transvaginal sonography in the preoperative assessment of myometrial invasion in high and low grade endometrial cancer and in comparison to frozen section in grade 1 disease","volume":"21","author":"Fishman","year":"2000","journal-title":"Eur J Gynaecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0110","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1046\/j.1525-1438.2002.01083.x","article-title":"Preoperative selection of patients with low-stage endometrial cancer at high risk of pelvic lymph node metastases","volume":"12","author":"van Doorn","year":"2002","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0115","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1006\/gyno.1994.1184","article-title":"The value of ultrasound in preoperative assessment of the myometrial and cervical invasion in endometrial carcinoma","volume":"54","author":"Artner","year":"1994","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0120","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ygyno.2011.11.016","article-title":"A prospective blinded comparison of the accuracy of transvaginal sonography and frozen section in the assessment of myometrial invasion in endometrial cancer","volume":"124","author":"Savelli","year":"2012","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0125","doi-asserted-by":"crossref","first-page":"565","DOI":"10.2214\/ajr.158.3.1738995","article-title":"Myometrial invasion by endometrial carcinoma: assessment by MR imaging","volume":"158","author":"Sironi","year":"1992","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0130","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.ygyno.2005.12.028","article-title":"MR imaging in endometrial carcinoma as a diagnostic tool for the absence of myometrial invasion","volume":"102","author":"Nakao","year":"2006","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0135","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1525-1438.2006.00414.x","article-title":"Preoperative and intraoperative assessment of myometrial invasion and histologic grade in endometrial cancer: role of magnetic resonance imaging and frozen section","volume":"16","author":"Sanjuan","year":"2006","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0140","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.ygyno.2006.10.007","article-title":"Accuracy of MR imaging for the prediction of myometrial invasion of endometrial carcinoma","volume":"104","author":"Chung","year":"2007","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0145","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1111\/aogs.12048","article-title":"Preoperative and intraoperative assessment of myometrial invasion in endometrial cancer: comparison of magnetic resonance imaging and frozen sections","volume":"92","author":"Kisu","year":"2013","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0150","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1067\/mob.2003.318","article-title":"Combined use of magnetic resonance imaging, CA 125 assay, histologic type, and histologic grade in the prediction of lymph node metastasis in endometrial carcinoma","volume":"188","author":"Todo","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0155","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/01443610601056418","article-title":"Preoperative assessment of deep myometrial and cervical invasion in endometrial carcinoma: comparison of magnetic resonance imaging and histopathologic evaluation","volume":"27","author":"Vasconcelos","year":"2007","journal-title":"J Obstet Gynaecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0160","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ijgo.2008.10.021","article-title":"Magnetic resonance imaging to identify risk of lymph node metastasis in patients with endometrial cancer","volume":"104","author":"Undurraga","year":"2009","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0165","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.ygyno.2006.03.016","article-title":"The diagnostic accuracy of magnetic resonance imaging in detecting cervical involvement in endometrial cancer","volume":"103","author":"Nagar","year":"2006","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0170","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.ejogrb.2007.02.029","article-title":"Evaluation of the sensitivity, specificity, positive and negative predictive values of preoperative magnetic resonance imaging for staging endometrial cancer. A prospective study of 100 cases at the Dorset Cancer Centre","volume":"137","author":"Ortashi","year":"2008","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0175","first-page":"930","article-title":"Intraoperative evaluation of depth of myometrial invasion in stage I endometrial adenocarcinoma","volume":"74","author":"Doering","year":"1989","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0180","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/0029-7844(96)00161-5","article-title":"Prognostic significance of gross myometrial invasion with endometrial cancer","volume":"88","author":"Larson","year":"1996","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0185","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1006\/gyno.1999.5694","article-title":"Clinical value of intraoperative gross examination in endometrial cancer","volume":"76","author":"Franchi","year":"2000","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0190","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1111\/j.1600-0412.2012.01406.x","article-title":"Validity of intraoperative gross examination of myometrial invasion in patients with endometrial cancer: a meta-analysis","volume":"91","author":"Mavromatis","year":"2012","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0195","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1111\/IGC.0b013e3181bff64b","article-title":"Frozen section underestimates the need for surgical staging in endometrial cancer patients","volume":"19","author":"Papadia","year":"2009","journal-title":"Int J Gynecol Cancer"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0200","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.ygyno.2009.07.007","article-title":"How accurate is frozen section histology of pelvic lymph nodes in patients with endometrial cancer?","volume":"115","author":"Pristauz","year":"2009","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0205","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ejogrb.2012.11.004","article-title":"Accuracy of frozen-section examination for myometrial invasion and grade in endometrial cancer","volume":"167","author":"Turan","year":"2013","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0210","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1159\/000010215","article-title":"Accuracy of intraoperative frozen-section diagnosis in stage I endometrial adenocarcinoma","volume":"49","author":"Kucera","year":"2000","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0215","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1097\/01.AOG.0000245444.14015.00","article-title":"A prospective blinded evaluation of the accuracy of frozen section for the surgical management of endometrial cancer","volume":"108","author":"Case","year":"2006","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0220","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/gyno.1994.1064","article-title":"Invasive endometrial cancer in uteri resected for atypical endometrial hyperplasia","volume":"52","author":"Janicek","year":"1994","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0225","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/cncr.21650","article-title":"Concurrent endometrial carcinoma in women with a biopsy diagnosis of atypical endometrial hyperplasia: a Gynecologic Oncology Group study","volume":"106","author":"Trimble","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0230","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ygyno.2011.12.436","article-title":"Patients with atypical hyperplasia of the endometrium should be treated in oncological centers","volume":"125","author":"Antonsen","year":"2012","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0235","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/0002-9378(63)90060-7","article-title":"Precursors of corpus cancer. IV. Adenomatous hyperplasia as stage O carcinoma of the endometrium","volume":"87","author":"Gusberg","year":"1963","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0240","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1093\/ajcp\/70.5.770","article-title":"Endometrial lesions in uteri resected for atypical endometrial hyperplasia","volume":"70","author":"Tavassoli","year":"1978","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0245","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1016\/S0002-9378(96)70599-9","article-title":"Use of computerized morphometric analyses of endometrial hyperplasias in the prediction of coexistent cancer","volume":"174","author":"Dunton","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0250","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1002\/1097-0142(19820615)49:12<2547::AID-CNCR2820491224>3.0.CO;2-0","article-title":"Evaluation of criteria for distinguishing atypical endometrial hyperplasia from well-differentiated carcinoma","volume":"49","author":"Kurman","year":"1982","journal-title":"Cancer"},{"key":"10.1016\/j.ygyno.2014.03.569_bb0255","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.7314\/APJCP.2012.13.5.1953","article-title":"Accuracy of frozen sections for intraoperative diagnosis of complex atypical endometrial hyperplasia","volume":"13","author":"Turan","year":"2012","journal-title":"Asian Pac J Cancer Prev"}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825814008117?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825814008117?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T06:57:07Z","timestamp":1538722627000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825814008117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":51,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["S0090825814008117"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2014.03.569","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2014,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intra-operative frozen section results reliably predict final pathology in endometrial cancer","name":"articletitle","label":"Article Title"},{"value":"Gynecologic Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygyno.2014.03.569","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}