{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T13:01:13Z","timestamp":1792674073221,"version":"4.5.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,8]],"date-time":"2017-03-08T00:00:00Z","timestamp":1488931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004332","name":"Seoul National University Hospital","doi-asserted-by":"publisher","award":["03-2015-0070"],"award-info":[{"award-number":["03-2015-0070"]}],"id":[{"id":"10.13039\/501100004332","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","gynecologiconcology-online.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.ygyno.2017.02.042","type":"journal-article","created":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T03:15:43Z","timestamp":1488856543000},"page":"361-365","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"title":["Predictive value of circulating tumor cells (CTCs) captured by microfluidic device in patients with epithelial ovarian cancer"],"prefix":"10.1016","volume":"145","author":[{"given":"Maria","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Jae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youngnam","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunshin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Hoon","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noh Hyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Sang","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.ygyno.2017.02.042_bb0005","doi-asserted-by":"crossref","first-page":"E359","DOI":"10.1002\/ijc.29210","article-title":"Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012","volume":"136","author":"Ferlay","year":"2015","journal-title":"Int. J. Cancer"},{"issue":"3","key":"10.1016\/j.ygyno.2017.02.042_bb0010","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1158\/1940-6207.CAPR-10-0195","article-title":"Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens","volume":"4","author":"Cramer","year":"2011","journal-title":"Cancer Prev. Res. (Phila.)"},{"key":"10.1016\/j.ygyno.2017.02.042_bb0015","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/978-94-017-7215-0_14","article-title":"The role of CA 125 as tumor marker: biochemical and clinical aspects","volume":"867","author":"Bottoni","year":"2015","journal-title":"Adv. Exp. Med. Biol."},{"issue":"18","key":"10.1016\/j.ygyno.2017.02.042_bb0020","doi-asserted-by":"crossref","first-page":"4664","DOI":"10.1158\/1078-0432.CCR-16-0316","article-title":"A prospective evaluation of early detection biomarkers for ovarian cancer in the European EPIC cohort","volume":"22","author":"Terry","year":"2016","journal-title":"Clin. Cancer Res."},{"issue":"1\u20132","key":"10.1016\/j.ygyno.2017.02.042_bb0025","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s10555-012-9398-0","article-title":"Clinical application of circulating tumor cells in breast cancer: overview of the current interventional trials","volume":"32","author":"Bidard","year":"2013","journal-title":"Cancer Metastasis Rev."},{"issue":"19","key":"10.1016\/j.ygyno.2017.02.042_bb0030","doi-asserted-by":"crossref","first-page":"6302","DOI":"10.1158\/1078-0432.CCR-08-0872","article-title":"Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer","volume":"14","author":"de Bono","year":"2008","journal-title":"Clin. Cancer Res."},{"issue":"19","key":"10.1016\/j.ygyno.2017.02.042_bb0035","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.1200\/JCO.2007.15.8923","article-title":"Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer","volume":"26","author":"Cohen","year":"2008","journal-title":"J. Clin. Oncol."},{"issue":"1","key":"10.1016\/j.ygyno.2017.02.042_bb0040","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.ygyno.2012.09.021","article-title":"Molecular characterization of circulating tumor cells in patients with ovarian cancer improves their prognostic significance\u2014a study of the OVCAD consortium","volume":"128","author":"Obermayr","year":"2013","journal-title":"Gynecol. Oncol."},{"issue":"3","key":"10.1016\/j.ygyno.2017.02.042_bb0045","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.ygyno.2014.06.013","article-title":"Prognostic analysis of invasive circulating tumor cells (iCTCs) in epithelial ovarian cancer","volume":"134","author":"Pearl","year":"2014","journal-title":"Gynecol. Oncol."},{"issue":"1","key":"10.1016\/j.ygyno.2017.02.042_bb0050","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ygyno.2008.09.021","article-title":"Clinical significance of circulating tumor cells detected by an invasion assay in peripheral blood of patients with ovarian cancer","volume":"112","author":"Fan","year":"2009","journal-title":"Gynecol. Oncol."},{"issue":"6","key":"10.1016\/j.ygyno.2017.02.042_bb0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130873","article-title":"Prognostic value of circulating tumor cells in ovarian cancer: a meta-analysis","volume":"10","author":"Zhou","year":"2015","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.ygyno.2017.02.042_bb0060","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.7150\/thno.9627","article-title":"High-purity isolation and recovery of circulating tumor cells using conducting polymer-deposited microfluidic device","volume":"4","author":"Jeon","year":"2014","journal-title":"Theranostics"},{"issue":"1","key":"10.1016\/j.ygyno.2017.02.042_bb0065","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.ygyno.2011.06.022","article-title":"Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a gynecologic oncology group study","volume":"123","author":"Behbakht","year":"2011","journal-title":"Gynecol. Oncol."},{"issue":"3","key":"10.1016\/j.ygyno.2017.02.042_bb0070","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.ygyno.2011.05.028","article-title":"Circulating tumor cells predict progression free survival and overall survival in patients with relapsed\/recurrent advanced ovarian cancer","volume":"122","author":"Poveda","year":"2011","journal-title":"Gynecol. Oncol."},{"issue":"5","key":"10.1016\/j.ygyno.2017.02.042_bb0075","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.cell.2014.07.013","article-title":"Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis","volume":"158","author":"Aceto","year":"2014","journal-title":"Cell"},{"issue":"2","key":"10.1016\/j.ygyno.2017.02.042_bb0080","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.ygyno.2003.08.004","article-title":"Preoperative detection of peripherally circulating cancer cells and its prognostic significance in ovarian cancer","volume":"91","author":"Judson","year":"2003","journal-title":"Gynecol. Oncol."},{"issue":"5","key":"10.1016\/j.ygyno.2017.02.042_bb0085","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1097\/IGC.0b013e318216cb91","article-title":"Molecular profiling and prognostic relevance of circulating tumor cells in the blood of ovarian cancer patients at primary diagnosis and after platinum-based chemotherapy","volume":"21","author":"Aktas","year":"2011","journal-title":"Int. J. Gynecol. Cancer"},{"issue":"3","key":"10.1016\/j.ygyno.2017.02.042_bb0090","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.ygyno.2006.05.049","article-title":"Detection of disseminated tumor cells in patients with gynecological cancers","volume":"103","author":"Fehm","year":"2006","journal-title":"Gynecol. Oncol."},{"issue":"2","key":"10.1016\/j.ygyno.2017.02.042_bb0095","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/j.ygyno.2013.08.006","article-title":"Predictive value of circulating tumor cells (CTCs) in newly-diagnosed and recurrent ovarian cancer patients","volume":"131","author":"Liu","year":"2013","journal-title":"Gynecol. Oncol."},{"issue":"11","key":"10.1016\/j.ygyno.2017.02.042_bb0100","first-page":"3363","article-title":"The added value of circulating tumor cells examination in ovarian cancer staging","volume":"5","author":"Kolostova","year":"2015","journal-title":"Am. J. Cancer Res."}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825817301634?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825817301634?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,3]],"date-time":"2018-09-03T16:20:41Z","timestamp":1535991641000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825817301634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0090825817301634"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2017.02.042","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predictive value of circulating tumor cells (CTCs) captured by microfluidic device in patients with epithelial ovarian cancer","name":"articletitle","label":"Article Title"},{"value":"Gynecologic Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygyno.2017.02.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}