{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:32:17Z","timestamp":1792157537197,"version":"4.4.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5T35AG038027-07"],"award-info":[{"award-number":["5T35AG038027-07"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["I01CX000934-01A1"],"award-info":[{"award-number":["I01CX000934-01A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21 167800"],"award-info":[{"award-number":["R21 167800"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gynecologiconcology-online.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.ygyno.2017.03.010","type":"journal-article","created":{"date-parts":[[2017,3,28]],"date-time":"2017-03-28T01:01:15Z","timestamp":1490662875000},"page":"526-530","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["Frailty measure is more predictive of outcomes after curative therapy for endometrial cancer than traditional risk factors in women 60 and older"],"prefix":"10.1016","volume":"145","author":[{"given":"Jane A.","family":"Driver","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akila N.","family":"Viswanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ygyno.2017.03.010_bb0005","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.ygyno.2005.11.009","article-title":"The effect of age on clinical\/pathologic features, surgical morbidity, and outcome in patients with endometrial cancer","volume":"101","author":"Lachance","year":"2006","journal-title":"Gynecol. Oncol."},{"issue":"1","key":"10.1016\/j.ygyno.2017.03.010_bb0010","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/gyno.2000.5917","article-title":"Age as a prognostic factor for recurrence in patients with endometrial carcinoma","volume":"79","author":"Mundt","year":"2000","journal-title":"Gynecol. Oncol."},{"issue":"11","key":"10.1016\/j.ygyno.2017.03.010_bb0015","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1002\/cncr.11830","article-title":"Is endometrial carcinoma intrinsically more aggressive in elderly patients?","volume":"98","author":"Alektiar","year":"2003","journal-title":"Cancer"},{"issue":"6","key":"10.1016\/j.ygyno.2017.03.010_bb0020","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1097\/AOG.0000000000001140","article-title":"Management for elderly women with advanced-stage, high-grade endometrial cancer","volume":"126","author":"Rauh-Hain","year":"2015","journal-title":"Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.ygyno.2017.03.010_bb0025","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1097\/IGC.0000000000000605","article-title":"Adjuvant treatment and clinical trials in elderly patients with endometrial cancer: a time for change?","volume":"26","author":"Clark","year":"2016","journal-title":"International Journal of Gynecological Cancer: Official Journal of the International Gynecological Cancer Society"},{"issue":"9213","key":"10.1016\/j.ygyno.2017.03.010_bb0030","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/S0140-6736(00)02139-5","article-title":"Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial. PORTEC study group. Post operative radiation therapy in endometrial carcinoma","volume":"355","author":"Creutzberg","year":"2000","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.ygyno.2017.03.010_bb0035","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ygyno.2010.10.038","article-title":"Is older age a poor prognostic factor in stage I and II endometrioid endometrial adenocarcinoma?","volume":"120","author":"Fleming","year":"2011","journal-title":"Gynecol. Oncol."},{"issue":"1","key":"10.1016\/j.ygyno.2017.03.010_bb0040","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ygyno.2015.04.010","article-title":"Risk-adjusted outcomes in elderly endometrial cancer patients: implications of the contrasting impact of age on progression-free and cause-specific survival","volume":"138","author":"AlHilli","year":"2015","journal-title":"Gynecol. Oncol."},{"issue":"8","key":"10.1016\/j.ygyno.2017.03.010_bb0045","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/s12094-012-0986-9","article-title":"Do comorbidity influences acute toxicity and outcome in elderly patients with endometrial cancer treated by adjuvant radiotherapy plus brachytherapy?","volume":"15","author":"Fiorentino","year":"2013","journal-title":"Clinical & Translational Oncology: Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico"},{"issue":"3","key":"10.1016\/j.ygyno.2017.03.010_bb0050","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1159\/000350859","article-title":"Chemotherapy in elderly patients with gynecological cancer","volume":"85","author":"Palaia","year":"2013","journal-title":"Oncology"},{"issue":"5","key":"10.1016\/j.ygyno.2017.03.010_bb0055","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/S0360-3016(97)00552-X","article-title":"Radiotherapy for cancer patients aged 80 and older: a study of effectiveness and side effects","volume":"39","author":"Zachariah","year":"1997","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"9868","key":"10.1016\/j.ygyno.2017.03.010_bb0060","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/S0140-6736(12)62167-9","article-title":"Frailty in elderly people","volume":"381","author":"Clegg","year":"2013","journal-title":"Lancet"},{"issue":"20","key":"10.1016\/j.ygyno.2017.03.010_bb0065","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1200\/JCO.2015.65.4327","article-title":"Validation of a prediction tool for chemotherapy toxicity in older adults with cancer","volume":"34","author":"Hurria","year":"2016","journal-title":"J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol."},{"issue":"2","key":"10.1016\/j.ygyno.2017.03.010_bb0070","doi-asserted-by":"crossref","first-page":"162","DOI":"10.6004\/jnccn.2012.0019","article-title":"Senior adult oncology","volume":"10","author":"Hurria","year":"2012","journal-title":"Journal of the National Comprehensive Cancer Network: JNCCN"},{"issue":"4","key":"10.1016\/j.ygyno.2017.03.010_bb0075","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.jgo.2015.05.003","article-title":"Non-hematologic predictors of mortality improve the prognostic value of the international prognostic scoring system for MDS in older adults","volume":"6","author":"Fega","year":"2015","journal-title":"Journal of Geriatric Oncology"},{"issue":"9","key":"10.1016\/j.ygyno.2017.03.010_bb0080","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.leukres.2013.05.013","article-title":"Geriatric assessment in older patients with acute myeloid leukemia: a retrospective study of associated treatment and outcomes","volume":"37","author":"Sherman","year":"2013","journal-title":"Leuk. Res."},{"issue":"13","key":"10.1016\/j.ygyno.2017.03.010_bb0085","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1016\/j.ejca.2010.06.002","article-title":"Sequential adjuvant chemotherapy and radiotherapy in endometrial cancer\u2014results from two randomised studies","volume":"46","author":"Hogberg","year":"2010","journal-title":"Eur. J. Cancer"},{"issue":"1","key":"10.1016\/j.ygyno.2017.03.010_bb0090","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ygyno.2006.02.007","article-title":"Final analysis of RTOG 9708: adjuvant postoperative irradiation combined with cisplatin\/paclitaxel chemotherapy following surgery for patients with high-risk endometrial cancer","volume":"103","author":"Greven","year":"2006","journal-title":"Gynecol. Oncol."},{"issue":"4","key":"10.1016\/j.ygyno.2017.03.010_bb0095","doi-asserted-by":"crossref","first-page":"e631","DOI":"10.1016\/j.ijrobp.2011.04.013","article-title":"Fifteen-year radiotherapy outcomes of the randomized PORTEC-1 trial for endometrial carcinoma","volume":"81","author":"Creutzberg","year":"2011","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"issue":"3","key":"10.1016\/j.ygyno.2017.03.010_bb0100","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.ygyno.2003.11.048","article-title":"A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a Gynecologic Oncology Group study","volume":"92","author":"Keys","year":"2004","journal-title":"Gynecol. Oncol."},{"issue":"3","key":"10.1016\/j.ygyno.2017.03.010_bb0105","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.ygyno.2011.09.005","article-title":"The importance of chemotherapy and radiation in uterine papillary serous carcinoma","volume":"123","author":"Viswanathan","year":"2011","journal-title":"Gynecol. Oncol."},{"issue":"7447","key":"10.1016\/j.ygyno.2017.03.010_bb0110","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nature12113","article-title":"Integrated genomic characterization of endometrial carcinoma","volume":"497","author":"Cancer Genome Atlas Research","year":"2013","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.ygyno.2017.03.010_bb0115","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.ygyno.2017.03.010_bb0120","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1471-2318-8-24","article-title":"A standard procedure for creating a frailty index","volume":"8","author":"Searle","year":"2008","journal-title":"BMC Geriatr."},{"issue":"000","key":"10.1016\/j.ygyno.2017.03.010_bb0125","first-page":"000","article-title":"Frailty as determined by a comprehensive geriatric assessment-derived deficit accumulation index in older patients with cancer who receive chemotherapy","volume":"000","author":"Cohen","year":"2016","journal-title":"Cancer"},{"issue":"12","key":"10.1016\/j.ygyno.2017.03.010_bb0130","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1245\/s10434-015-4763-1","article-title":"Radiographic sarcopenia and self-reported exhaustion independently predict NSQIP serious complications after pancreaticoduodenectomy in older adults","volume":"22","author":"Sur","year":"2015","journal-title":"Ann. Surg. Oncol."}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825817302263?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825817302263?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:57:29Z","timestamp":1777474649000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825817302263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,6]]}},"alternative-id":["S0090825817302263"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2017.03.010","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Frailty measure is more predictive of outcomes after curative therapy for endometrial cancer than traditional risk factors in women 60 and older","name":"articletitle","label":"Article Title"},{"value":"Gynecologic Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygyno.2017.03.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}