{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T20:54:23Z","timestamp":1780433663240,"version":"3.54.1"},"reference-count":15,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gynecologiconcology-online.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.ygyno.2020.11.007","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T18:33:07Z","timestamp":1606242787000},"page":"413-417","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Continued medical treatment for persistent early endometrial cancer in young women"],"prefix":"10.1016","volume":"160","author":[{"given":"Angela","family":"Cho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-Wha","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Yeol","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae-Yeon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae-Shik","family":"Suh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Hyeok","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Man","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Tak","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ygyno.2020.11.007_bb0005","first-page":"9","article-title":"Cancer statistics, 2014","volume":"64","author":"Siegel","year":"2014","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.ygyno.2020.11.007_bb0010","series-title":"Annual Report of Cancer Statistics in Korea in 2017","author":"N.C.C. Korea Central Cancer Registry","year":"2019"},{"issue":"2 Suppl","key":"10.1016\/j.ygyno.2020.11.007_bb0015","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1016\/j.ygyno.2008.07.056","article-title":"Sparing fertility in young patients with endometrial cancer","volume":"111","author":"Chiva","year":"2008","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2020.11.007_bb0020","author":"National Comprehensive Cancer Network"},{"issue":"3","key":"10.1016\/j.ygyno.2020.11.007_bb0025","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/ijgo.12882","article-title":"A systematic review and meta-analysis of prognostic factors for remission in fertility-sparing management of endometrial atypical hyperplasia and adenocarcinoma","volume":"146","author":"Guillon","year":"2019","journal-title":"Int. J. Gynecol. Obstet."},{"issue":"7","key":"10.1016\/j.ygyno.2020.11.007_bb0030","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1097\/IGC.0000000000000493","article-title":"European Society of Gynecological Oncology Task Force for fertility preservation: clinical recommendations for fertility-sparing management in young endometrial cancer patients","volume":"25","author":"Rodolakis","year":"2015","journal-title":"Int. J. Gynecol. Cancer"},{"issue":"1","key":"10.1016\/j.ygyno.2020.11.007_bb0035","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/AOG.0b013e3182964ce3","article-title":"Hormonal therapy for women with stage IA endometrial cancer of all grades","volume":"122","author":"Park","year":"2013","journal-title":"Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.ygyno.2020.11.007_bb0040","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1136\/ijgc-2018-000036","article-title":"Pregnancy and oncologic outcomes after fertility-sparing management for early stage endometrioid endometrial cancer","volume":"29","author":"Chae","year":"2019","journal-title":"Int. J. Gynecol. Cancer"},{"issue":"2","key":"10.1016\/j.ygyno.2020.11.007_bb0045","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.ygyno.2014.02.020","article-title":"Fertility sparing treatment of complex atypical hyperplasia and low grade endometrial cancer using oral progestin","volume":"133","author":"Simpson","year":"2014","journal-title":"Gynecol. Oncol."},{"issue":"4","key":"10.1016\/j.ygyno.2020.11.007_bb0050","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1136\/ijgc-2018-000081","article-title":"Impact of treatment duration in fertility-preserving management of endometrial cancer or atypical endometrial hyperplasia","volume":"29","author":"Wang","year":"2019","journal-title":"Int. J. Gynecol. Cancer"},{"issue":"2 Pt 2","key":"10.1016\/j.ygyno.2020.11.007_bb0055","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/AOG.0b013e3181719b92","article-title":"Reverse of progestin-resistant atypical endometrial hyperplasia by metformin and oral contraceptives","volume":"112","author":"Shen","year":"2008","journal-title":"Obstet. Gynecol."},{"issue":"3","key":"10.1016\/j.ygyno.2020.11.007_bb0060","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.ygyno.2015.09.078","article-title":"Prognostic factors of oncological and reproductive outcomes in fertility-sparing treatment of complex atypical hyperplasia and low-grade endometrial cancer using oral progestin in Chinese patients","volume":"139","author":"Zhou","year":"2015","journal-title":"Gynecol. Oncol."},{"issue":"4","key":"10.1016\/j.ygyno.2020.11.007_bb0065","doi-asserted-by":"crossref","first-page":"266.e1","DOI":"10.1016\/j.ajog.2012.08.011","article-title":"Regression, relapse, and live birth rates with fertility-sparing therapy for endometrial cancer and atypical complex endometrial hyperplasia: a systematic review and metaanalysis","volume":"207","author":"Gallos","year":"2012","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.ygyno.2020.11.007_bb0070","doi-asserted-by":"crossref","DOI":"10.3802\/jgo.2018.29.e21","article-title":"Is repeated high-dose medroxyprogesterone acetate (MPA) therapy permissible for patients with early stage endometrial cancer or atypical endometrial hyperplasia who desire preserving fertility?","volume":"29","author":"Yamagami","year":"2018","journal-title":"J. Gynecol. Oncol."},{"issue":"6","key":"10.1016\/j.ygyno.2020.11.007_bb0075","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1007\/s10147-019-01404-2","article-title":"Prolonged conservative treatment in patients with recurrent endometrial cancer after primary fertility-sparing therapy: 15-year experience","volume":"24","author":"Wang","year":"2019","journal-title":"Int. J. Clin. Oncol."}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825820341159?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825820341159?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T03:57:07Z","timestamp":1758772627000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825820341159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S0090825820341159"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2020.11.007","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Continued medical treatment for persistent early endometrial cancer in young women","name":"articletitle","label":"Article Title"},{"value":"Gynecologic Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygyno.2020.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}