{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T06:08:20Z","timestamp":1783490900774,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","gynecologiconcology-online.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.ygyno.2020.12.003","type":"journal-article","created":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T08:27:24Z","timestamp":1608712044000},"page":"389-395","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Effect of surgical approach on risk of recurrence after vaginal brachytherapy in early-stage high-intermediate risk endometrial cancer"],"prefix":"10.1016","volume":"160","author":[{"given":"L.","family":"Philp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tannenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Haber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Saini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. St","family":"Laurent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"James","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.M.","family":"Feltmate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.L.","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.B.","family":"Growdon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.ygyno.2020.12.003_bb0005","first-page":"7","article-title":"Cancer statistics, 2020","volume":"70","author":"Siegel","year":"2020","journal-title":"CA Cancer J. Clin."},{"issue":"10023","key":"10.1016\/j.ygyno.2020.12.003_bb0010","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/S0140-6736(15)00130-0","article-title":"Endometrial cancer","volume":"387","author":"Morice","year":"2016","journal-title":"Lancet."},{"issue":"3","key":"10.1016\/j.ygyno.2020.12.003_bb0015","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S1470-2045(17)30068-2","article-title":"A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study","volume":"18","author":"Rossi","year":"2017","journal-title":"Lancet Oncol."},{"issue":"1","key":"10.1016\/j.ygyno.2020.12.003_bb0020","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ygyno.2008.01.023","article-title":"Prospective assessment of lymphatic dissemination in endometrial cancer: a paradigm shift in surgical staging","volume":"109","author":"Mariani","year":"2008","journal-title":"Gynecol. Oncol."},{"issue":"9213","key":"10.1016\/j.ygyno.2020.12.003_bb0025","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/S0140-6736(00)02139-5","article-title":"Surgery and postoperative radiotherapy versus surgery alone for patients with stage-1 endometrial carcinoma: multicentre randomised trial","volume":"355","author":"Creutzberg","year":"2000","journal-title":"Lancet."},{"issue":"3","key":"10.1016\/j.ygyno.2020.12.003_bb0030","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.ygyno.2003.11.048","article-title":"A phase III trial of surgery with or without adjunctive external pelvic radiation therapy in intermediate risk endometrial adenocarcinoma: a gynecologic oncology group study","volume":"92","author":"Keys","year":"2004","journal-title":"Gynecol. Oncol."},{"key":"10.1016\/j.ygyno.2020.12.003_bb0035","series-title":"Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial","first-page":"2","volume":"375","author":"Nout","year":"2010"},{"issue":"12","key":"10.1016\/j.ygyno.2020.12.003_bb0040","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1001\/jama.2017.2068","article-title":"Effect of total laparoscopic hysterectomy vs total abdominal hysterectomy on disease-free survival among women with stage i endometrial cancer: a randomized clinical trial","volume":"317","author":"Janda","year":"2017","journal-title":"JAMA - J Am Med Assoc."},{"issue":"7","key":"10.1016\/j.ygyno.2020.12.003_bb0045","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1200\/JCO.2011.38.8645","article-title":"Recurrence and survival after random assignment to laparoscopy versus laparotomy for comprehensive surgical staging of uterine cancer: gynecologic oncology group LAP2 study","volume":"30","author":"Walker","year":"2012","journal-title":"J. Clin. Oncol."},{"issue":"3","key":"10.1016\/j.ygyno.2020.12.003_bb0050","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.ygyno.2016.10.016","article-title":"Impact of histology and surgical approach on survival among women with early-stage, high-grade uterine cancer: an NRG oncology\/gynecologic oncology group ancillary analysis","volume":"143","author":"Fader","year":"2016","journal-title":"Gynecol. Oncol."},{"issue":"2","key":"10.1016\/j.ygyno.2020.12.003_bb0055","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ygyno.2012.04.028","article-title":"Minimally invasive surgery versus laparotomy in women with high grade endometrial cancer: a multi-site study performed at high volume cancer centers","volume":"126","author":"Fader","year":"2012","journal-title":"Gynecol. Oncol."},{"issue":"2016","key":"10.1016\/j.ygyno.2020.12.003_bb0060","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ejca.2016.07.001","article-title":"Long-term oncological safety of minimally invasive surgery in high-risk endometrial cancer","volume":"65","author":"Koskas","year":"2016","journal-title":"Eur. J. Cancer"},{"issue":"20","key":"10.1016\/j.ygyno.2020.12.003_bb0065","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1056\/NEJMoa1806395","article-title":"Minimally invasive versus abdominal radical hysterectomy for cervical Cancer","volume":"379","author":"Ramirez","year":"2018","journal-title":"N. Engl. J. Med."},{"issue":"20","key":"10.1016\/j.ygyno.2020.12.003_bb0070","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1056\/NEJMoa1804923","article-title":"Survival after minimally invasive radical hysterectomy for early-stage cervical cancer","volume":"379","author":"Melamed","year":"2018","journal-title":"N. Engl. J. Med."},{"issue":"32","key":"10.1016\/j.ygyno.2020.12.003_bb0075","doi-asserted-by":"crossref","first-page":"5331","DOI":"10.1200\/JCO.2009.22.3248","article-title":"Laparoscopy compared with laparotomy for comprehensive surgical staging of uterine cancer: gynecologic oncology group study LAP2","volume":"27","author":"Walker","year":"2009","journal-title":"J. Clin. Oncol."},{"issue":"3","key":"10.1016\/j.ygyno.2020.12.003_bb0080","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1097\/IGC.0b013e318244248c","article-title":"Laparoscopic versus abdominal approach to endometrial cancer: a 10-year retrospective multicenter analysis","volume":"22","author":"Palomba","year":"2012","journal-title":"Int. J. Gynecol. Cancer"},{"issue":"8","key":"10.1016\/j.ygyno.2020.12.003_bb0085","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S1470-2045(10)70143-1","article-title":"Safety of laparoscopy versus laparotomy in early-stage endometrial cancer: a randomised trial","volume":"11","author":"Mourits","year":"2010","journal-title":"Lancet Oncol."},{"issue":"4","key":"10.1016\/j.ygyno.2020.12.003_bb0090","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.ajog.2005.02.131","article-title":"A prospective randomized comparison between laparoscopic and laparotomic approaches in women with early stage endometrial cancer: a focus on the quality of life","volume":"193","author":"Zullo","year":"2005","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"3","key":"10.1016\/j.ygyno.2020.12.003_bb0095","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.ygyno.2014.11.014","article-title":"The trend towards minimally invasive surgery (MIS) for endometrial cancer: an ACS-NSQIP evaluation of surgical outcomes","volume":"136","author":"Scalici","year":"2015","journal-title":"Gynecol. Oncol."},{"issue":"2","key":"10.1016\/j.ygyno.2020.12.003_bb0100","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1136\/ijgc-2019-000838","article-title":"A comparison of disease recurrence between robotic versus laparotomy approach in patients with intermediate-risk endometrial cancer","volume":"30","author":"Song","year":"2020","journal-title":"Int. J. Gynecol. Cancer"},{"issue":"9717","key":"10.1016\/j.ygyno.2020.12.003_bb0105","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S0140-6736(09)62163-2","article-title":"Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial","volume":"375","author":"Nout","year":"2010","journal-title":"Lancet."},{"issue":"3","key":"10.1016\/j.ygyno.2020.12.003_bb0110","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/AOG.0b013e318264f848","article-title":"Vaginal cuff dehiscence in a series of 12,398 hysterectomies: effect of different types of colpotomy and vaginal closure","volume":"120","author":"Ucella","year":"2012","journal-title":"Obstet. Gynecol."},{"issue":"8 Suppl","key":"10.1016\/j.ygyno.2020.12.003_bb0115","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1002\/1097-0142(19901015)60:8+<2035::AID-CNCR2820601515>3.0.CO;2-8","article-title":"Surgical pathologic spread patterns of endometrial cancer A Gynecologic Oncology Group Study","volume":"60","author":"Creasman","year":"1987","journal-title":"Cancer."},{"issue":"1","key":"10.1016\/j.ygyno.2020.12.003_bb0120","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ygyno.2019.04.002","article-title":"Lymph node dissection in endometrial cancer and clinical outcome: a population-based study in 5546 patients","volume":"154","author":"P\u00f6lcher","year":"2019","journal-title":"Gynecol. Oncol."},{"issue":"1041","key":"10.1016\/j.ygyno.2020.12.003_bb0125","doi-asserted-by":"crossref","DOI":"10.1259\/bjr.20140146","article-title":"Recent developments and best practice in brachytherapy treatment planning","volume":"87","author":"Lee","year":"2014","journal-title":"Br J Radiol"},{"issue":"6","key":"10.1016\/j.ygyno.2020.12.003_bb0130","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.jmig.2018.01.010","article-title":"Robotic, laparoscopic, or open hysterectomy: surgical outcomes by approach in endometrial Cancer","volume":"25","author":"Beck","year":"2018","journal-title":"J. Minim. Invasive Gynecol."},{"issue":"6","key":"10.1016\/j.ygyno.2020.12.003_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2019.07.009","article-title":"Impact of surgical approach on oncologic outcomes in women undergoing radical hysterectomy for cervical cancer","volume":"221","author":"Cusimano","year":"2019","journal-title":"Am J Obstet Gynecol"}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825820341743?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825820341743?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T03:54:50Z","timestamp":1758772490000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825820341743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["S0090825820341743"],"URL":"https:\/\/doi.org\/10.1016\/j.ygyno.2020.12.003","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of surgical approach on risk of recurrence after vaginal brachytherapy in early-stage high-intermediate risk endometrial cancer","name":"articletitle","label":"Article Title"},{"value":"Gynecologic Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ygyno.2020.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}