{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T21:17:33Z","timestamp":1774559853660,"version":"3.50.1"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Natural Sciences and Engineering Research Council of Canada (NSERC)"},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["1P01HD075750-1"],"award-info":[{"award-number":["1P01HD075750-1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hormones and Behavior"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.yhbeh.2016.04.007","type":"journal-article","created":{"date-parts":[[2016,5,15]],"date-time":"2016-05-15T03:45:19Z","timestamp":1463283919000},"page":"56-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats"],"prefix":"10.1016","volume":"82","author":[{"given":"Dan","family":"Madularu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Praveen","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason R.","family":"Yee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"Kenkel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waqqas M.","family":"Shams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig F.","family":"Ferris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wayne G.","family":"Brake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.yhbeh.2016.04.007_bb0005","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/S0278-5846(03)00161-1","article-title":"Adjunctive estrogen treatment in women with chronic schizophrenia: a double-blind, randomized, and placebo-controlled trial","volume":"27","author":"Akhondzadeh","year":"2003","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0010","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.1210\/en.2012-1458","article-title":"Estrogen receptors are found in glia and at extranuclear neuronal sites in the dorsal striatum of female rats: evidence for cholinergic but not dopaminergic colocalization","volume":"153","author":"Almey","year":"2012","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0015","doi-asserted-by":"crossref","first-page":"136","DOI":"10.3389\/fnbeh.2013.00136","article-title":"Deficits in latent inhibition induced by estradiol replacement are ameliorated by haloperidol treatment","volume":"7","author":"Almey","year":"2013","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0020","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0006-8993(86)91547-7","article-title":"Behavioral effects of a single neuroleptic treatment grow with the passage of time","volume":"385","author":"Antelman","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0025","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/0006-8993(91)91709-A","article-title":"One experience with \u2018lower\u2019 or \u2018higher\u2019 intensity stressors, respectively enhances or diminishes responsiveness to haloperidol weeks later: implications for understanding drug variability","volume":"566","author":"Antelman","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0030","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0024-3205(92)90084-3","article-title":"One brief exposure to a psychological stressor induces long-lasting, time-dependent sensitization of both the cataleptic and neurochemical responses to haloperidol","volume":"51","author":"Antelman","year":"1992","journal-title":"Life Sci."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0035","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0006-8993(94)91229-7","article-title":"Sex differences in the rapid and acute effects of estrogen on striatal D2 dopamine receptor binding","volume":"637","author":"Bazzett","year":"1994","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0040","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0304-3940(90)90618-J","article-title":"Estrogen rapidly potentiates amphetamine-induced striatal dopamine release and rotational behavior during microdialysis","volume":"118","author":"Becker","year":"1990","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0045","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0169-328X(97)00082-X","article-title":"Ovariectomy and estradiol treatment affect the dopamine transporter and its gene expression in the rat brain","volume":"46","author":"Bosse","year":"1997","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0050","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1677\/JOE-07-0017","article-title":"Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system","volume":"193","author":"Brailoiu","year":"2007","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0055","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S0730-725X(03)00204-2","article-title":"Changes in MRI signal intensity during hypercapnic challenge under conscious and anesthetized conditions","volume":"21","author":"Brevard","year":"2003","journal-title":"Magn. Reson. Imaging"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0060","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0920-9964(98)00070-X","article-title":"Differences in distribution of ages of onset in males and females with schizophrenia","volume":"33","author":"Castle","year":"1998","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.euroneuro.2015.10.002","article-title":"5-HT receptors modulate the expression of antipsychotic-induced dopamine supersensitivity","author":"Charron","year":"2015","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0070","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/0006-8993(79)90547-X","article-title":"Estrogen increases both spiperone-induced catalepsy and brain levels of [3H]spiperone in the rat","volume":"172","author":"Chiodo","year":"1979","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0075","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/0091-3057(82)90489-0","article-title":"Estrogen and haloperidol-induced versus handling-related catalepsy in male rats","volume":"17","author":"De Ryck","year":"1982","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2015.03.012","article-title":"Antipsychotic treatment leading to dopamine supersensitivity persistently alters nucleus accumbens function","author":"El Hage","year":"2015","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0085","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0022-3565(25)32149-X","article-title":"Antidopaminergic effect of estrogens at the striatal level","volume":"214","author":"Euvrard","year":"1980","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0090","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1016\/j.pnpbp.2007.08.025","article-title":"The amphetamine-induced sensitized state as a model of schizophrenia","volume":"31","author":"Featherstone","year":"2007","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0095","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1523\/JNEUROSCI.3801-04.2005","article-title":"Estrogen influences cocaine-induced blood oxygen level-dependent signal changes in female rats","volume":"25","author":"Febo","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0100","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3389\/fneur.2014.00094","article-title":"Studies on the Q175 knock-in model of Huntington's disease using functional imaging in awake mice: evidence of olfactory dysfunction","volume":"5","author":"Ferris","year":"2014","journal-title":"Front. Neurol."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0105","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1016\/j.euroneuro.2012.10.013","article-title":"Haloperidol modulates midbrain-prefrontal functional connectivity in the rat brain","volume":"23","author":"Gass","year":"2013","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0110","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1006\/nimg.2001.1037","article-title":"Thresholding of statistical maps in functional neuroimaging using the false discovery rate","volume":"15","author":"Genovese","year":"2002","journal-title":"NeuroImage"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0115","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1177\/070674370204700504","article-title":"The role of estrogen in schizophrenia: implications for schizophrenia practice guidelines for women","volume":"47","author":"Grigoriadis","year":"2002","journal-title":"Can. J. Psychiatr."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0120","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0014-2999(80)90081-3","article-title":"Estrogen treatment enhances dopamine receptor sensitivity in the rat striatum","volume":"61","author":"Hruska","year":"1980","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0125","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1126\/science.7189902","article-title":"Increased dopamine receptor sensitivity after estrogen treatment using the rat rotation model","volume":"208","author":"Hruska","year":"1980","journal-title":"Science"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0130","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0091-3057(82)90162-9","article-title":"Effects of estrogen on striatal dopamine receptor function in male and female rats","volume":"16","author":"Hruska","year":"1982","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0135","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1176\/appi.ajp.157.4.514","article-title":"Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia","volume":"157","author":"Kapur","year":"2000","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0140","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jneumeth.2005.04.011","article-title":"Procedure for minimizing stress for fMRI studies in conscious rats","volume":"148","author":"King","year":"2005","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0145","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0920-9964(96)82949-5","article-title":"A clinical trial of the effects of estrogen in acutely psychotic women","volume":"20","author":"Kulkarni","year":"1996","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0150","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0920-9964(00)00088-8","article-title":"Estrogen \u2014 a potential treatment for schizophrenia","volume":"48","author":"Kulkarni","year":"2001","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0155","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/BF02246489","article-title":"Schizophrenia and psychostimulant abuse: a review and re-analysis of clinical evidence","volume":"121","author":"LeDuc","year":"1995","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0160","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/ejn.12401","article-title":"Estrogen potentiates the behavioral and nucleus accumbens dopamine response to continuous haloperidol treatment in female rats","volume":"39","author":"Madularu","year":"2014","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2015.05.025","article-title":"Changes in brain volume in response to estradiol levels, amphetamine sensitization and haloperidol treatment in awake female rats","author":"Madularu","year":"2015","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0170","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.psyneuen.2015.02.022","article-title":"Integration of neural networks activated by amphetamine in females with different estrogen levels: a functional imaging study in awake rats","volume":"56","author":"Madularu","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0175","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/j.jpain.2005.07.007","article-title":"Pharmacokinetics and effects of 17beta-estradiol and progesterone implants in ovariectomized rats","volume":"6","author":"Mannino","year":"2005","journal-title":"J. Pain"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0180","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1111\/j.1365-2826.2008.01743.x","article-title":"Oestrogen receptor alpha localisation in the prefrontal cortex of three mammalian species","volume":"20","author":"Montague","year":"2008","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0185","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0169-328X(97)00351-3","article-title":"Differential distribution and regulation of estrogen receptor-alpha and -beta mRNA within the female rat brain","volume":"54","author":"Osterlund","year":"1998","journal-title":"Brain Res. Mol. Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0190","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1080\/15287397809529700","article-title":"Concentrations of circulating steroids in normal prepubertal and adult male and female humans, chimpanzees, rhesus monkeys, rats, mice, and hamsters: a literature survey","volume":"4","author":"Overpeck","year":"1978","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0195","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1002\/syn.890190108","article-title":"Amphetamine-induced time-dependent sensitization of dopamine neurotransmission in the dorsal and ventral striatum: a microdialysis study in behaving rats","volume":"19","author":"Paulson","year":"1995","journal-title":"Synapse"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0200","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1007\/BF02244248","article-title":"Time course of transient behavioral depression and persistent behavioral sensitization in relation to regional brain monoamine concentrations during amphetamine withdrawal in rats","volume":"103","author":"Paulson","year":"1991","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0205","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.bbr.2008.03.037","article-title":"Amphetamine sensitization in rats as an animal model of schizophrenia","volume":"191","author":"Peleg-Raibstein","year":"2008","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0210","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/j.pnpbp.2008.06.002","article-title":"Acute dehydroepiandrosterone treatment exerts different effects on dopamine and serotonin turnover ratios in the rat corpus striatum and nucleus accumbens","volume":"32","author":"Perez-Neri","year":"2008","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0215","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0006-8993(91)91706-7","article-title":"Estradiol enhances behavioral sensitization to cocaine and amphetamine-stimulated striatal [3H]dopamine release","volume":"566","author":"Peris","year":"1991","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0220","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1093\/schbul\/20.1.203","article-title":"Can estradiol modulate schizophrenic symptomatology?","volume":"20","author":"Riecher-Rossler","year":"1994","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0225","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/BF00431451","article-title":"Behavioral sensitization: characterization of enduring changes in rotational behavior produced by intermittent injections of amphetamine in male and female rats","volume":"84","author":"Robinson","year":"1984","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0230","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0006-8993(82)90690-4","article-title":"Long-term facilitation of amphetamine-induced rotational behavior and striatal dopamine release produced by a single exposure to amphetamine: sex differences","volume":"253","author":"Robinson","year":"1982","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0235","doi-asserted-by":"crossref","first-page":"e141","DOI":"10.1371\/journal.pmed.0020141","article-title":"A systematic review of the prevalence of schizophrenia","volume":"2","author":"Saha","year":"2005","journal-title":"PLoS Med."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0240","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.pnpbp.2013.06.008","article-title":"Can antipsychotic treatment contribute to drug addiction in schizophrenia?","volume":"52","author":"Samaha","year":"2014","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0245","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1523\/JNEUROSCI.5416-06.2007","article-title":"\u201cBreakthrough\u201d dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time","volume":"27","author":"Samaha","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0250","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.biopsych.2008.01.010","article-title":"Less is more: antipsychotic drug effects are greater with transient rather than continuous delivery","volume":"64","author":"Samaha","year":"2008","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0255","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1111\/j.1755-5949.2010.00163.x","article-title":"Steroids-dopamine interactions in the pathophysiology and treatment of CNS disorders","volume":"16","author":"Sanchez","year":"2010","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0260","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.psyneuen.2011.06.012","article-title":"Effect of a chronic treatment with 17beta-estradiol on striatal dopamine neurotransmission and the Akt\/GSK3 signaling pathway in the brain of ovariectomized monkeys","volume":"37","author":"Sanchez","year":"2012","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2014.06.020","article-title":"Estradiol and isotype-selective estrogen receptor agonists modulate the mesocortical dopaminergic system in gonadectomized female rats","author":"Sarvari","year":"2014","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0270","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/BF03033244","article-title":"Behavioural sensitization in addiction, schizophrenia, Parkinson's disease and dyskinesia","volume":"10","author":"Schmidt","year":"2006","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0275","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/sj.mp.4000336","article-title":"Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors","volume":"3","author":"Seeman","year":"1998","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0280","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/cne.1054","article-title":"Distribution of estrogen receptor beta immunoreactivity in the rat central nervous system","volume":"436","author":"Shughrue","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0285","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1159\/000333296","article-title":"Novel G protein-coupled oestrogen receptor GPR30 shows changes in mRNA expression in the rat brain over the oestrous cycle","volume":"21","author":"Spary","year":"2013","journal-title":"Neurosignals"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0290","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0920-9964(03)00009-4","article-title":"Amphetamine-sensitized animals show a sensorimotor gating and neurochemical abnormality similar to that of schizophrenia","volume":"64","author":"Tenn","year":"2003","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0295","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/0091-3057(88)90015-9","article-title":"Haloperidol, but not apomorphine, differentially affects low response rates of male and female Wistar rats","volume":"29","author":"Van Hest","year":"1988","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0300","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1016\/j.biopsych.2010.11.010","article-title":"Effect of chronic antipsychotic treatment on brain structure: a serial magnetic resonance imaging study with ex vivo and postmortem confirmation","volume":"69","author":"Vernon","year":"2011","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0305","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.biopsych.2011.12.004","article-title":"Contrasting effects of haloperidol and lithium on rodent brain structure: a magnetic resonance imaging study with postmortem confirmation","volume":"71","author":"Vernon","year":"2012","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0310","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.biopsych.2013.09.012","article-title":"Reduced cortical volume and elevated astrocyte density in rats chronically treated with antipsychotic drugs-linking magnetic resonance imaging findings to cellular pathology","volume":"75","author":"Vernon","year":"2014","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0315","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1523\/JNEUROSCI.16-07-02411.1996","article-title":"D1 dopamine receptor activation is necessary for the induction of sensitization by amphetamine in the ventral tegmental area","volume":"16","author":"Vezina","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0320","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1046\/j.1471-4159.1996.67010352.x","article-title":"Acute and repeated systemic amphetamine administration: effects on extracellular glutamate, aspartate, and serine levels in rat ventral tegmental area and nucleus accumbens","volume":"67","author":"Xue","year":"1996","journal-title":"J. Neurochem."},{"key":"10.1016\/j.yhbeh.2016.04.007_bb0325","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0306-4522(00)00344-4","article-title":"GABA(B) receptors: altered coupling to G-proteins in rats sensitized to amphetamine","volume":"101","author":"Zhang","year":"2000","journal-title":"Neuroscience"}],"container-title":["Hormones and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X15301987?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X15301987?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T14:19:55Z","timestamp":1748960395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0018506X15301987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":65,"alternative-id":["S0018506X15301987"],"URL":"https:\/\/doi.org\/10.1016\/j.yhbeh.2016.04.007","relation":{},"ISSN":["0018-506X"],"issn-type":[{"value":"0018-506X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats","name":"articletitle","label":"Article Title"},{"value":"Hormones and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yhbeh.2016.04.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}