{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:48:47Z","timestamp":1787240927244,"version":"build-2736575974"},"reference-count":75,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,2,1]],"date-time":"2018-02-01T00:00:00Z","timestamp":1517443200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100008641","name":"Chung Shan Medical University","doi-asserted-by":"publisher","award":["CSMU-INT-106-02"],"award-info":[{"award-number":["CSMU-INT-106-02"]}],"id":[{"id":"10.13039\/501100008641","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Chung Hsing University and Chung Shan Medical University","award":["NCHU-CSMU-10607"],"award-info":[{"award-number":["NCHU-CSMU-10607"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hormones and Behavior"],"published-print":{"date-parts":[[2018,2]]},"DOI":"10.1016\/j.yhbeh.2017.12.019","type":"journal-article","created":{"date-parts":[[2018,1,10]],"date-time":"2018-01-10T23:04:06Z","timestamp":1515625446000},"page":"173-182","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Role of hypothalamic leptin-LepRb signaling in NPY-CART-mediated appetite suppression in amphetamine-treated rats"],"prefix":"10.1016","volume":"98","author":[{"given":"Shu-Chen","family":"Chu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Ni","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeng-Rung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Han","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yih-Shou","family":"Hsieh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Yih","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yhbeh.2017.12.019_bb0005","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1006\/mcne.2000.0947","article-title":"Selective introduction of antisense oligonucleotides into single adult CNS progenitor cells using electroporation demonstrates the requirement of STAT3 activation for CNTF-induced gliogenesis","volume":"17","author":"Aberg","year":"2001","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0010","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1177\/0004563213489670","article-title":"The biochemical utility of chromogranin A, chromogranin B and cocaine- and amphetamine-regulated transcript for neuroendocrine neoplasia","volume":"51","author":"Bech","year":"2014","journal-title":"Ann. Clin. Biochem."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0015","doi-asserted-by":"crossref","first-page":"3485","DOI":"10.1210\/endo.139.8.6154","article-title":"Expression of leptin receptor isoforms in rat brain microvessels","volume":"139","author":"Bj\u00f8rbaek","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0020","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.molmet.2016.03.003","article-title":"PI3K p110\u03b2 subunit in leptin receptor expressing cells is required for the acute hypophagia induced by endotoxemia","volume":"5","author":"Borges","year":"2016","journal-title":"Mol. Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0025","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/sms.12194","article-title":"A time-efficient reduction of fat mass in 4days with exercise and caloric restriction","volume":"25","author":"Calbet","year":"2015","journal-title":"Scand. J. Med. Sci. Sports"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0030","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1172\/JCI200317490","article-title":"The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men","volume":"111","author":"Chan","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0035","doi-asserted-by":"crossref","first-page":"3380","DOI":"10.1523\/JNEUROSCI.4031-09.2010","article-title":"Neuropeptide Y suppresses anorexigenic output from the ventromedial nucleus of the hypothalamus","volume":"30","author":"Chee","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0040","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/BF02256608","article-title":"Evidence for the involvement of dopamine D1 and D2 receptors in mediating the decrease of food intake during repeated treatment with amphetamine","volume":"8","author":"Chen","year":"2001","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0045","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.fct.2011.12.016","article-title":"Dioscorea nipponica Makino inhibits migration and invasion of human oral cancer HSC-3 cells by transcriptional inhibition of matrix metalloproteinase-2 through modulation of CREB and AP-1 activity","volume":"50","author":"Chien","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0055","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.yhbeh.2014.11.005","article-title":"Both neuropeptide Y knockdown and Y1 receptor inhibition modulate CART-mediated appetite control","volume":"67","author":"Chu","year":"2015","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0060","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cmet.2013.05.010","article-title":"Leptin at the intersection of neuroendocrinology and metabolism: current evidence and therapeutic perspectives","volume":"18","author":"Dalamaga","year":"2013","journal-title":"Cell Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0065","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2015.27","article-title":"Argon blocks the expression of locomotor sensitization to amphetamine through antagonism at the vesicular monoamine transporter-2 and mu-opioid receptor in the nucleus accumbens","volume":"5","author":"David","year":"2015","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0070","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.cmet.2014.07.022","article-title":"The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus","volume":"20","author":"Dodd","year":"2014","journal-title":"Cell Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0075","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1002\/(SICI)1096-9861(19980615)395:4<535::AID-CNE9>3.0.CO;2-2","article-title":"Distributions of leptin receptor mRNA isoforms in the rat brain","volume":"395","author":"Elmquist","year":"1998","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0080","doi-asserted-by":"crossref","first-page":"11582","DOI":"10.1523\/JNEUROSCI.5712-08.2009","article-title":"Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity","volume":"29","author":"Ernst","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0085","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1210\/me.2015-1232","article-title":"Minireview: CNS mechanisms of leptin action","volume":"30","author":"Flak","year":"2016","journal-title":"Mol. Endocrinol."},{"issue":"51","key":"10.1016\/j.yhbeh.2017.12.019_bb0090","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.neuron.2006.09.006","article-title":"Leptin regulation of the mesoaccumbens dopamine pathway","volume":"21","author":"Fulton","year":"2006","journal-title":"Neuron"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030485","article-title":"Over-expression of leptin receptors in hypothalamic POMC neurons increases susceptibility to diet-induced obesity","volume":"7","author":"Gamber","year":"2012","journal-title":"PLoS One"},{"issue":"101","key":"10.1016\/j.yhbeh.2017.12.019_bb0100","doi-asserted-by":"crossref","first-page":"4661","DOI":"10.1073\/pnas.0303992101","article-title":"Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation","volume":"30","author":"Gao","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0105","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1210\/en.2007-0945","article-title":"Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein\/neuropeptide Y neurons for normal energy homeostasis","volume":"149","author":"Gong","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0110","doi-asserted-by":"crossref","first-page":"E939","DOI":"10.1152\/ajpendo.00343.2016","article-title":"Fourth-ventricle leptin infusions dose-dependently activate hypothalamic signal transducer and activator of transcription 3","volume":"311","author":"Harris","year":"2016","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0115","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1113\/JP271257","article-title":"Effects of acute and chronic systemic methamphetamine on respiratory, cardiovascular and metabolic function, and cardiorespiratory reflexes","volume":"594","author":"Hassan","year":"2016","journal-title":"J. Physiol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0120","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1111\/bph.13520","article-title":"Key role of heat shock protein 90 in leptin-induced STAT3 activation and feeding regulation","volume":"173","author":"Hosoi","year":"2016","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0125","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.regpep.2004.11.007","article-title":"Amphetamine, an appetite suppressant, decreases neuropeptide Y immunoreactivity in rat hypothalamic paraventriculum","volume":"127","author":"Hsieh","year":"2005","journal-title":"Regul. Pept."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0130","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1152\/ajpendo.00195.2006","article-title":"Intracerebral administration of protein kinase A (PKA) or c-AMP response element binding protein (CREB) antisense oligonucleiotide can modulate amphetamine-mediated appetite suppression in free-moving rats","volume":"292","author":"Hsieh","year":"2007","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0135","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s00204-012-0947-7","article-title":"Neuropeptide Y Y1 receptor knockdown can modify glutathione peroxidase and c-AMP response element binding protein in phenylpropanolamine-treated rats","volume":"87","author":"Hsieh","year":"2013","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0140","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1756-6606-6-46","article-title":"The neuropeptide Y Y1 receptor knockdown modulates activator protein 1-involved feeding behavior in amphetamine-treated rats","volume":"6","author":"Hsieh","year":"2013","journal-title":"Mol. Brain"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0145","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.neuro.2015.03.011","article-title":"Involvement of oxidative stress in the regulation of NPY\/CART-mediated appetite control in amphetamine-treated rats","volume":"48","author":"Hsieh","year":"2015","journal-title":"NeuroToxicology"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0150","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0167-0115(95)00110-W","article-title":"ICV administration of anti-NPY antisense oligonucleotide: effects on feeding behavior, body weight, peptide content and peptide release","volume":"59","author":"Hulsey","year":"1995","journal-title":"Regul. Pept."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0155","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/ijo.2016.169","article-title":"Roanthocyanidins potentiate hypothalamic leptin\/STAT3 signalling and Pomc gene expression in rats with diet-induced obesity","volume":"41","author":"Ibars","year":"2017","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0160","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1210\/me.2015-1232","article-title":"Minireview: CNS mechanisms of leptin action","volume":"30","author":"Jonathan","year":"2016","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0165","doi-asserted-by":"crossref","first-page":"3255","DOI":"10.1007\/s00018-010-0414-7","article-title":"Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis","volume":"67","author":"Jordan","year":"2010","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0170","doi-asserted-by":"crossref","first-page":"8905","DOI":"10.1074\/jbc.M109.079590","article-title":"Enhanced hypothalamic leptin signaling in mice lacking dopamine D2 receptors","volume":"285","author":"Kim","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0175","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1096\/fj.02-0805fje","article-title":"A role for arcuate cocaine and amphetamine-regulated transcript in hyperphagia, thermogenesis, and cold adaptation","volume":"17","author":"Kong","year":"2003","journal-title":"FASEB J."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0180","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/BF02256023","article-title":"Co-administration of dopamine D1 and D2 agonists additively decreases daily food intake, body weight and hypothalamic neuropeptide Y level","volume":"9","author":"Kuo","year":"2002","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0185","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1038\/sj.bjp.0706754","article-title":"Hypothalamic neuropeptide Y (NPY) and the attenuation of hyperphagia in streptozotocin diabetic rats treated with dopamine D1\/D2 agonists","volume":"148","author":"Kuo","year":"2006","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0190","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0024-3205(01)01401-1","article-title":"Role of hypothalamic neuropeptide Y (NPY) in the change of feeding behavior induced by repeated treatment of amphetamine","volume":"70","author":"Kuo","year":"2001","journal-title":"Life Sci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0195","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.cbi.2009.03.013","article-title":"Amphetamine-evoked changes of oxidative stress and neuropeptide Y gene expression in hypothalamus: regulation by the protein kinase C-delta signaling","volume":"180","author":"Kuo","year":"2009","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0200","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1089\/ars.2010.3738","article-title":"Role of reactive oxygen species-related enzymes in neuropeptide Y and proopiomelanocortin-mediated appetite control: a study using atypical protein kinase C knockdown","volume":"15","author":"Kuo","year":"2011","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0205","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1016\/j.neuropharm.2011.11.014","article-title":"NF-\u03baB knockdown can modulate amphetamine-mediated feeding response","volume":"62","author":"Kuo","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0210","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.neuropharm.2012.06.018","article-title":"Involvement of neuropeptide Y Y1 receptor in the regulation of amphetamine-mediated appetite suppression","volume":"63","author":"Kuo","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0215","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.npep.2016.03.006","article-title":"Temperature dependence of the control of energy homeostasis requires CART signaling","volume":"59","author":"Lau","year":"2016","journal-title":"Neuropeptides"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0220","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1177\/0269881116667708","article-title":"Low-anxiety rats are more sensitive to amphetamine in comparison to high-anxiety rats","volume":"31","author":"Lehner","year":"2017","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0225","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.cmet.2009.06.011","article-title":"Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding","volume":"10","author":"Leinninger","year":"2009","journal-title":"Cell Metab."},{"issue":"14","key":"10.1016\/j.yhbeh.2017.12.019_bb0230","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.cmet.2011.06.016","article-title":"Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance","volume":"7","author":"Leinninger","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0235","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1038\/sj.ijo.0802142","article-title":"Leptin: a review of its peripheral actions and interactions","volume":"26","author":"Margetic","year":"2002","journal-title":"Int. J. Obes. Relat. Metab. Disord."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0240","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.yfrne.2011.06.001","article-title":"The role of NPY in hypothalamic mediated food intake","volume":"32","author":"Mercer","year":"2011","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0245","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.brainres.2009.09.077","article-title":"A possible role of neuropeptide Y in depression and stress","volume":"1314","author":"Morales-Medina","year":"2010","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0250","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/cne.902900305","article-title":"Neuronal localization of neuropeptide Y gene expression in rat brain","volume":"290","author":"Morris","year":"1989","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0255","doi-asserted-by":"crossref","first-page":"E1247","DOI":"10.1152\/ajpendo.00274.2009","article-title":"Recent advances in understanding leptin signaling and leptin resistance","volume":"297","author":"Morris","year":"2009","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0260","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.metabol.2014.09.010","article-title":"Structure, production and signaling of leptin","volume":"64","author":"M\u00fcnzberg","year":"2015","journal-title":"Metabolism"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0265","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/chemse\/23.2.249","article-title":"Current status of antisense DNA methods in behavioral studies","volume":"23","author":"Ogawa","year":"1998","journal-title":"Chem. Senses"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0270","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.metabol.2014.08.004","article-title":"Physiology of leptin: energy homeostasis, neuroendocrine function and metabolism","volume":"64","author":"Park","year":"2015","journal-title":"Metabolism"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0275","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.brainres.2011.01.010","article-title":"Molecular mapping of mouse brain regions innervated by leptin receptor-expressing cells","volume":"1378","author":"Patterson","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0280","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0285","doi-asserted-by":"crossref","first-page":"965","DOI":"10.2119\/molmed.2010.00259","article-title":"STATus and context within the mammalian nervous system","volume":"17","author":"Rajan","year":"2011","journal-title":"Mol. Med."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0290","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.molmet.2014.07.008","article-title":"Leptin receptor neurons in the dorsomedial hypothalamus are key regulators of energy expenditure and body weight, but not food intake","volume":"3","author":"Rezai-Zadeh","year":"2014","journal-title":"Mol. Metab."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0295","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.pbb.2010.04.015","article-title":"Involvement of nitric oxide in lipopolysaccharide induced anorexia","volume":"97","author":"Riediger","year":"2010","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0300","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1126\/science.6264602","article-title":"Glucoreceptors controlling feeding and blood glucose: location in the hindbrain","volume":"213","author":"Ritter","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0305","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.physbeh.2008.04.005","article-title":"Molecular and neural mediators of leptin action","volume":"94","author":"Robertson","year":"2008","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0310","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0014-2999(97)01014-5","article-title":"Centrally administered oligodeoxynucleotides in rats: occurrence of non-specific effects","volume":"331","author":"Sch\u00f6bitz","year":"1997","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0315","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.brainres.2014.07.043","article-title":"Cocaine- and amphetamine-regulated transcript peptide increases mitochondrial respiratory chain complex II activity and protects against oxygen-glucose deprivation in neurons","volume":"1582","author":"Sha","year":"2014","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0320","doi-asserted-by":"crossref","first-page":"4429","DOI":"10.1074\/jbc.M110.196402","article-title":"Development and characterization of high affinity leptins and leptin antagonists","volume":"286","author":"Shpilman","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0325","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s12035-012-8240-6","article-title":"Functional heterogeneity of arcuate nucleus pro-opiomelanocortin neurons: implications for diverging melanocortin pathways","volume":"45","author":"Sohn","year":"2012","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0330","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s002130100901","article-title":"Hypolocomotor effects of acute and daily d-amphetamine in mice lacking the dopamine transporter","volume":"159","author":"Spielewoy","year":"2001","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0335","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1177\/34.5.3517144","article-title":"The unlabeled antibody method: comparison of peroxidase-antiperoxidase with avidin-biotin complex by a new method of quantification","volume":"34","author":"Sternberger","year":"1986","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0340","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.npep.2009.11.005","article-title":"Differential effect of prolonged food restriction and fasting on hypothalamic malonyl-CoA concentration and expression of orexigenic and anorexigenic neuropeptides genes in rats","volume":"44","author":"Sucajtys-Szulc","year":"2010","journal-title":"Neuropeptides"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0345","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/0024-3205(89)90494-3","article-title":"Comparative study of cathinone and amphetamine on brown adipose thermogenesis","volume":"44","author":"Tariq","year":"1989","journal-title":"Life Sci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0350","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.biopsych.2012.10.026","article-title":"Presynaptic leptin action suppresses excitatory synaptic transmission onto ventral tegmental area dopamine neurons","volume":"73","author":"Thompson","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0355","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1124\/jpet.105.091512","article-title":"The CART (cocaine- and amphetamine-regulated transcript) system in appetite and drug addiction","volume":"320","author":"Vicentic","year":"2007","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0360","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1210\/en.2006-1119","article-title":"Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding","volume":"148","author":"Xu","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0365","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.appet.2017.02.010","article-title":"Participation of ghrelin signalling in the reciprocal regulation of hypothalamic NPY\/POMC-mediated appetite control in amphetamine-treated rats","volume":"113","author":"Yu","year":"2017","journal-title":"Appetite"},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0370","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0304-3940(93)90299-Z","article-title":"Antisense oligodeoxynucleotide reduces brain dopamine D2 receptors: behavioral correlates","volume":"161","author":"Zhang","year":"1993","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0375","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1523\/JNEUROSCI.3223-10.2011","article-title":"Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits","volume":"31","author":"Zhang","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2017.12.019_bb0380","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1126\/science.8140422","article-title":"Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6","volume":"264","author":"Zhong","year":"1994","journal-title":"Science"}],"container-title":["Hormones and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X17304397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X17304397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T10:31:02Z","timestamp":1575541862000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0018506X17304397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":75,"alternative-id":["S0018506X17304397"],"URL":"https:\/\/doi.org\/10.1016\/j.yhbeh.2017.12.019","relation":{},"ISSN":["0018-506X"],"issn-type":[{"value":"0018-506X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of hypothalamic leptin-LepRb signaling in NPY-CART-mediated appetite suppression in amphetamine-treated rats","name":"articletitle","label":"Article Title"},{"value":"Hormones and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yhbeh.2017.12.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}