{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:02:40Z","timestamp":1791266560037,"version":"4.1.0"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81773392"],"award-info":[{"award-number":["81773392"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81472935"],"award-info":[{"award-number":["81472935"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hormones and Behavior"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.yhbeh.2018.05.012","type":"journal-article","created":{"date-parts":[[2018,5,25]],"date-time":"2018-05-25T06:22:37Z","timestamp":1527229357000},"page":"129-138","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Bisphenol-A inhibits improvement of testosterone in anxiety- and depression-like behaviors in gonadectomied male mice"],"prefix":"10.1016","volume":"102","author":[{"given":"Yvfeng","family":"Liang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingjie","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kesheng","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.yhbeh.2018.05.012_bb0005","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1006\/hbeh.2002.1838","article-title":"Testosterone rapidly reduces anxiety in male house mice (Mus musculus)","volume":"42","author":"Aikey","year":"2002","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neulet.2018.01.030","article-title":"Behavioral effects of the combined use of alcohol and energy drinks on alcohol hangover in an experimental mice model","volume":"670","author":"Asorey","year":"2018","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0015","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.tox.2013.02.012","article-title":"The influence of study design and sex-differences on results from developmental neurotoxicity studies of bisphenol A, implications for toxicity testing","volume":"311","author":"Beronius","year":"2013","journal-title":"Toxicology"},{"issue":"5","key":"10.1016\/j.yhbeh.2018.05.012_bb0020","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1542\/peds.2011-1335","article-title":"Impact of early-life bisphenol A exposure on behavior and executive function in children","volume":"128","author":"Braun","year":"2011","journal-title":"Pediatrics"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0025","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1093\/toxsci\/kft035","article-title":"Prenatal bisphenol A exposure alters sex-specific estrogen receptor expression in the neonatal rat hypothalamus and amygdala","volume":"133","author":"Cao","year":"2013","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0030","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1530\/REP-13-0501","article-title":"Sex-specific Esr2 mRNA expression in the rat hypothalamus and amygdala is altered by neonatal bisphenol A exposure","volume":"147","author":"Cao","year":"2014","journal-title":"Reproduction"},{"issue":"5","key":"10.1016\/j.yhbeh.2018.05.012_bb0035","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.yhbeh.2012.03.001","article-title":"Testosterone and imipramine have antidepressant effects in socially isolated male but not female rats","volume":"61","author":"Carrier","year":"2012","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0040","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/j.biopsych.2011.11.028","article-title":"Extracellular signal-regulated kinase 2 signaling in the hippocampal dentate gyrus mediates the antidepressant effects of testosterone","volume":"71","author":"Carrier","year":"2012","journal-title":"Biol. Psychiatry"},{"issue":"7","key":"10.1016\/j.yhbeh.2018.05.012_bb0045","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.brainres.2014.05.010","article-title":"Sex differences in the adult HPA axis and affective behaviors are altered by perinatal exposure to a low dose of bisphenol A","volume":"1571","author":"Chen","year":"2014","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0050","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.yhbeh.2010.07.008","article-title":"Gestational exposure to bisphenol A and cross-fostering affect behaviors in juvenile mice","volume":"58","author":"Cox","year":"2010","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0055","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.yhbeh.2017.05.019","article-title":"Sex differences and sex hormones in anxiety-like behavior of aging rats","volume":"93","author":"Domonkos","year":"2017","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0060","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.tox.2011.07.011","article-title":"Hypermethylation of estrogen receptor promoter region in adult testis of rats exposed neonatally to bisphenol A","volume":"289","author":"Doshi","year":"2011","journal-title":"Toxicology"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0065","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.tox.2015.04.012","article-title":"Extensive metabolism and route-dependent pharmacokinetics of bisphenol A (BPA) in neonatal mice following oral or subcutaneous administration","volume":"333","author":"Draganov","year":"2015","journal-title":"Toxicology"},{"issue":"5","key":"10.1016\/j.yhbeh.2018.05.012_bb0070","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.psyneuen.2004.11.001","article-title":"Testosterone's anti-anxiety and analgesic effects may be due in part to actions of its 5\u03b1-reduced metabolites in the hippocampus","volume":"30","author":"Edinger","year":"2005","journal-title":"Psychoneuroendocrinology"},{"issue":"2","key":"10.1016\/j.yhbeh.2018.05.012_bb0075","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.yhbeh.2006.03.003","article-title":"Intrahippocampal administration of an androgen receptor antagonist, flutamide, can increase anxiety-like behavior in intact and DHT-replaced male rats","volume":"50","author":"Edinger","year":"2006","journal-title":"Horm. Behav."},{"issue":"5","key":"10.1016\/j.yhbeh.2018.05.012_bb0080","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.pedn.2009.05.006","article-title":"Bisphenol A exposure: human risk and health policy","volume":"25","author":"Erler","year":"2010","journal-title":"J. Pediatr. Nurs."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0085","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.neuro.2014.10.003","article-title":"Prenatal bisphenol A exposure and maternally reported behavior in boys and girls","volume":"45","author":"Evans","year":"2014","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0090","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.yhbeh.2017.05.014","article-title":"Anti-androgenic effects of bisphenol-A on spatial memory and synaptic plasticity of the hippocampus in mice","volume":"93","author":"Fang","year":"2017","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0095","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0091-3057(99)00136-7","article-title":"Perinatal exposure to the estrogenic pollutant bisphenol A affects behavior in male and female rats","volume":"64","author":"Farabollini","year":"1999","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0100","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.yhbeh.2008.07.013","article-title":"Androgens with activity at estrogen receptor beta have anxiolytic and cognitive-enhancing effects in male rats and mice","volume":"54","author":"Frye","year":"2008","journal-title":"Horm. Behav."},{"issue":"1","key":"10.1016\/j.yhbeh.2018.05.012_bb0105","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.brainres.2005.11.028","article-title":"Prenatal exposure to bisphenol A impairs sexual differentiation of exploratory behavior and increases depression-like behavior in rats","volume":"1068","author":"Fujimoto","year":"2006","journal-title":"Brain Res."},{"issue":"4","key":"10.1016\/j.yhbeh.2018.05.012_bb0110","doi-asserted-by":"crossref","first-page":"539","DOI":"10.2131\/jts.38.539","article-title":"Postnatal exposure to low-dose bisphenol A influences various emotional conditions","volume":"38","author":"Fujimoto","year":"2013","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0115","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.yhbeh.2007.05.006","article-title":"Developmental exposure to low-dose estrogenic endocrine disruptors alters sex differences in exploration and emotional responses in mice","volume":"52","author":"Gioiosa","year":"2007","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0120","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/j.yhbeh.2013.02.016","article-title":"The effects of bisphenol A on emotional behavior depend upon the timing of exposure, age and gender in mice","volume":"63","author":"Gioiosa","year":"2013","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0125","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.etap.2010.06.003","article-title":"Effects of prenatal and postnatal exposure to a low dose of bisphenol A on behavior and memory in rats","volume":"30","author":"Gonalves","year":"2010","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0130","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1017\/S0954579403000233","article-title":"Salivary testosterone diurnal variation and psychopathology in adolescent males and females: individual differences and developmental effects","volume":"15","author":"Granger","year":"2003","journal-title":"Dev. Psychopathol."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0135","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1210\/en.2006-1626","article-title":"Effects of androgens and estradiol on spine synapse formation in the prefrontal cortex of normal and testicular feminization mutant male rats","volume":"148","author":"Hajszan","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0140","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.yhbeh.2007.09.012","article-title":"An alternate pathway for androgen regulation of brain function: activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5alpha-androstane-3beta,17beta-diol","volume":"53","author":"Handa","year":"2008","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0145","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.envres.2013.06.004","article-title":"Prenatal and early childhood bisphenol A concentrations and behavior in school-aged children","volume":"126","author":"Harley","year":"2013","journal-title":"Environ. Res."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0150","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.brainres.2014.12.011","article-title":"Rapid increase of spines by dihydrotestosterone and testosterone in hippocampal neurons: dependence on synaptic androgen receptor and kinase networks","volume":"1621","author":"Hatanaka","year":"2015","journal-title":"Brain Res."},{"issue":"2","key":"10.1016\/j.yhbeh.2018.05.012_bb0155","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.pbb.2012.04.005","article-title":"The anxiolytic effect of testosterone in the rat is mediated via the androgen receptor","volume":"102","author":"Hodosy","year":"2012","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0160","doi-asserted-by":"crossref","first-page":"11715","DOI":"10.1073\/pnas.1107958108","article-title":"Disruption of adult expression of sexually selected traits by developmental exposure to bisphenol A","volume":"108","author":"Ja\u0161arevic","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.yhbeh.2018.05.012_bb0165","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.yhbeh.2012.09.009","article-title":"Sex and dose-dependent effects of developmental exposure to bisphenol A on anxiety and spatial learning in deer mice (Peromyscus maniculatus bairdii) offspring","volume":"63","author":"Ja\u0161arevi\u0107","year":"2013","journal-title":"Horm. Behav."},{"issue":"3","key":"10.1016\/j.yhbeh.2018.05.012_bb0170","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.nlm.2005.10.007","article-title":"Effects of gonadectomy and androgen supplementation on attention in male rats","volume":"85","author":"Johnson","year":"2006","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0175","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.yhbeh.2012.02.011","article-title":"Perinatal BPA exposure demasculinizes males in measures of affect but has no effect on water maze learning in adulthood","volume":"61","author":"Jones","year":"2012","journal-title":"Horm. Behav."},{"issue":"6","key":"10.1016\/j.yhbeh.2018.05.012_bb0180","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1037\/1064-1297.15.6.529","article-title":"Testosterone supplementation for depressed men: current research and suggested treatment guidelines","volume":"15","author":"Kanayama","year":"2007","journal-title":"Exp. Clin. Psychopharmacol."},{"issue":"5","key":"10.1016\/j.yhbeh.2018.05.012_bb0185","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1073\/pnas.1417731112","article-title":"Low-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish","volume":"112","author":"Kinch","year":"2015","journal-title":"Proc. Ntl. Acad. Sci. U. S."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0190","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.tox.2017.01.010","article-title":"Anxiety like behavior due to perinatal exposure to bisphenol-A is associated with decrease in excitatory to inhibitory synaptic density of male mouse brain","volume":"378","author":"Kumar","year":"2017","journal-title":"Toxicology"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0195","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ecoenv.2017.04.009","article-title":"In vitro and in vivo estrogenic activity of BPA, BPF and BPS in zebrafish-specific assays","volume":"142","author":"Le Fol","year":"2017","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0200","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/toxsci\/kfg150","article-title":"Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor","volume":"75","author":"Lee","year":"2003","journal-title":"Toxicol. Sci."},{"issue":"3","key":"10.1016\/j.yhbeh.2018.05.012_bb0205","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1210\/en.2007-1053","article-title":"Bisphenol A prevents the synaptogenic response to testosterone in the brain of adult male rat","volume":"149","author":"Leranth","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0210","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1126\/science.290.5489.131","article-title":"Molecular and neuronal substrate for the selective attenuation of anxiety","volume":"290","author":"L\u00f6w","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0215","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.fct.2013.07.037","article-title":"Pubertal exposure to bisphenol A increases anxiety-like behavior and decreases acetylcholinesterase activity of hippocampus in adult male mice","volume":"60","author":"Luo","year":"2013","journal-title":"Food Chem. Toxicol."},{"issue":"2","key":"10.1016\/j.yhbeh.2018.05.012_bb0220","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1093\/toxsci\/kfu085","article-title":"Maternal bisphenol A diet induces anxiety-like behavior in female juvenile with neuroimmun eactivation","volume":"140","author":"Luo","year":"2014","journal-title":"Toxicol. Sci. Off. J. Soc. Toxicol."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0225","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.chemosphere.2017.06.050","article-title":"Paternal bisphenol a diet changes prefrontal cortex proteome and provokes behavioral dysfunction in male offspring","volume":"184","author":"Luo","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0230","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1289\/ehp.7633","article-title":"The environmental estrogen bisphenol A inhibits estradiol-induced hippocampal synaptogenesis","volume":"113","author":"MacLusky","year":"2005","journal-title":"Environ. Health Perspect."},{"issue":"2","key":"10.1016\/j.yhbeh.2018.05.012_bb0235","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.pnpbp.2012.06.016","article-title":"Effects of perinatal exposure to low dose of bisphenol A on anxiety like behavior and dopamine metabolites in brain","volume":"39","author":"Matsuda","year":"2012","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0240","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.neuropharm.2011.08.040","article-title":"The GABA system in anxiety and depression and its therapeutic potential","volume":"62","author":"Mohler","year":"2012","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0245","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuro.2015.06.002","article-title":"Bisphenol A: human exposure and neurobehavior","volume":"49","author":"Mustieles","year":"2015","journal-title":"Neurotoxicology"},{"issue":"1\u20132","key":"10.1016\/j.yhbeh.2018.05.012_bb0250","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.toxlet.2010.02.002","article-title":"Bisphenol A may cause testosterone reduction by adversely affecting both testis and pituitary systems similar to estradiol","volume":"194","author":"Nakamura","year":"2010","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0255","article-title":"Opening the black box of endocrine disruption of brain development: lessons from the characterization of bisphenol A","author":"Nesan","year":"2017","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0260","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s11357-009-9088-1","article-title":"Chronic administration of androgens with actions at estrogen receptor beta have anti-anxiety and cognitive-enhancing effects in male rats","volume":"31","author":"Osborne","year":"2009","journal-title":"Age"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0265","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.yhbeh.2008.01.008","article-title":"Neonatal exposure to endocrine active compounds or an ER beta agonist increases adult anxiety and aggression in gonadally intact male rats","volume":"53","author":"Patisaul","year":"2008","journal-title":"Horm. Behav."},{"issue":"8","key":"10.1016\/j.yhbeh.2018.05.012_bb0270","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1289\/ehp.1104492","article-title":"Prenatal bisphenol a exposure and child behavior in an innerity cohort","volume":"120","author":"Perera","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0275","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.envres.2016.07.028","article-title":"Bisphenol A exposure and symptoms of anxiety and depression among inner city children at 10\u201312\u202fyears of age","volume":"151","author":"Perera","year":"2016","journal-title":"Environ. Res."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0280","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/j.neuroscience.2010.02.051","article-title":"Corticosterone-regulated actions in the rat brain are affected by perinatal exposure to low dose of bisphenol A","volume":"167","author":"Poimenova","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0285","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.bbr.2006.08.035","article-title":"The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress","volume":"175","author":"Qi","year":"2006","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0290","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.nbd.2008.05.003","article-title":"Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress","volume":"31","author":"Qi","year":"2008","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0295","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/toxsci\/kfu074","article-title":"Investigation of the effects of subchronic low dose oral exposure to bisphenol A (BPA) and ethinyl estradiol (EE) on estrogen receptor expression in the juvenile and adult female rat hypothalamus","volume":"140","author":"Rebuli","year":"2014","journal-title":"Toxicol. Sci."},{"issue":"1","key":"10.1016\/j.yhbeh.2018.05.012_bb0300","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.yhbeh.2009.03.021","article-title":"Gonadectomy negatively impacts social behavior of adolescent male primates","volume":"56","author":"Richards","year":"2009","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0305","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.yhbeh.2006.01.007","article-title":"Developmental exposure to environmental estrogens alters anxiety and spatial memory in female mice","volume":"50","author":"Ryan","year":"2006","journal-title":"Horm. Behav."},{"issue":"1","key":"10.1016\/j.yhbeh.2018.05.012_bb0310","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/npp.2009.83","article-title":"The neurocircuitry of fear, stress, and anxiety disorders","volume":"35","author":"Shin","year":"2010","journal-title":"Neuropsychopharmacology"},{"issue":"8","key":"10.1016\/j.yhbeh.2018.05.012_bb0315","doi-asserted-by":"crossref","first-page":"3251","DOI":"10.1523\/JNEUROSCI.22-08-03251.2002","article-title":"Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression","volume":"22","author":"Shirayama","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0320","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1677\/joe.0.1580327","article-title":"Several environmental oestrogens are also anti-androgens","volume":"158","author":"Sohoni","year":"1998","journal-title":"J. Endocrinol."},{"issue":"1","key":"10.1016\/j.yhbeh.2018.05.012_bb0325","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1471-4159.2001.00054.x","article-title":"The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory","volume":"76","author":"Sweatt","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0330","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1289\/ehp.1002514","article-title":"Similarity of bisphenol A pharmacokinetics in rhesus monkeys and mice: relevance for human exposure","volume":"119","author":"Taylor","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0335","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1590\/S1413-81232012000200015","article-title":"Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol A","volume":"17","author":"Vandenberg","year":"2012","journal-title":"Ci\u00ean Sa\u00fade Colet."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0340","doi-asserted-by":"crossref","DOI":"10.4161\/endo.25411","article-title":"Rapid estrogenic signaling activities of the modified (chlorinated, sulfonated, and glucuronidated) endocrine disruptor bisphenol A","volume":"1","author":"Vi\u00f1as","year":"2013","journal-title":"Endocr. Disruptors"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0345","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.bbr.2010.10.009","article-title":"Antidepressant-like properties of alpha2-containing GABA (A) receptors","volume":"217","author":"Vollenweider","year":"2011","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0350","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.reprotox.2014.01.007","article-title":"Bisphenol A (BPA) pharmacokinetics with daily oral bolus or continuous exposure via silastic capsules in pregnant rhesus monkeys: relevance for human exposures","volume":"45","author":"vom Saal","year":"2014","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0355","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.brainres.2013.07.018","article-title":"Adolescent exposure to bisphenol-A increases anxiety and sucrose preference but impairs spatial memory in rats independent of sex","volume":"1529","author":"Weinstein","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0360","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.yhbeh.2010.10.001","article-title":"The role of bisphenol A in shaping the brain, epigenome and behavior","volume":"59","author":"Wolstenholme","year":"2011","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0365","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.bbr.2007.09.013","article-title":"Effects of d-cycloserine on the behavior and ERK activity in the amygdala: role of individual anxiety levels","volume":"187","author":"Wu","year":"2008","journal-title":"Behav. Brain Res."},{"issue":"2\u20133","key":"10.1016\/j.yhbeh.2018.05.012_bb0370","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.tox.2005.08.006","article-title":"Evaluation of androgen receptor transcriptional activities of bisphenol A, octylphenol and nonylphenol in vitro","volume":"216","author":"Xu","year":"2005","journal-title":"Toxicology"},{"issue":"1","key":"10.1016\/j.yhbeh.2018.05.012_bb0375","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1002\/etc.18","article-title":"Perinatal exposure to bisphenol-A changes N-methyl-d-aspartate receptor expression in the hippocampus of male rat offspring","volume":"29","author":"Xu","year":"2010","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0380","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.taap.2010.09.007","article-title":"Bisphenol-A rapidly promotes dynamic changes in hippocampal dendritic morphology through estrogen receptor-mediated pathway by concomitant phosphorylation of NMDA receptor subunit NR2B","volume":"249","author":"Xu","year":"2010","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0385","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.neuropharm.2011.04.027","article-title":"Sex-specific influence of exposure to bisphenol-A between adolescence and young adulthood on mouse behaviors","volume":"61","author":"Xu","year":"2011","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0390","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.yhbeh.2012.08.005","article-title":"Gestational and lactational exposure to bisphenol-A affects anxiety- and depression-like behaviors in mice","volume":"62","author":"Xu","year":"2012","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0395","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1002\/hipo.22336","article-title":"Bisphenol A regulates the estrogen receptor alpha signaling in developing hippocampus of male rats through estrogen receptor","volume":"24","author":"Xu","year":"2014","journal-title":"Hippocampus"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0400","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.chemosphere.2014.07.021","article-title":"Sex-specific effects of long-term exposure to bisphenol-A on anxiety- and depression-like behaviors in adult mice","volume":"120","author":"Xu","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0405","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.chemosphere.2017.12.086","article-title":"Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons","volume":"195","author":"Yang","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.yhbeh.2018.05.012_bb0410","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.neuroscience.2010.03.029","article-title":"Effects of neonatal flutamide treatment on hippocampal neurogenesis and synaptogenesis correlate with depression-like behaviors in preadolescent male rats","volume":"169","author":"Zhang","year":"2010","journal-title":"Neuroscience"}],"container-title":["Hormones and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X18300096?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X18300096?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,5]],"date-time":"2019-12-05T10:32:46Z","timestamp":1575541966000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0018506X18300096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":82,"alternative-id":["S0018506X18300096"],"URL":"https:\/\/doi.org\/10.1016\/j.yhbeh.2018.05.012","relation":{},"ISSN":["0018-506X"],"issn-type":[{"value":"0018-506X","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bisphenol-A inhibits improvement of testosterone in anxiety- and depression-like behaviors in gonadectomied male mice","name":"articletitle","label":"Article Title"},{"value":"Hormones and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yhbeh.2018.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}