{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T10:00:45Z","timestamp":1758189645047,"version":"3.44.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009633","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hormones and Behavior"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.yhbeh.2021.105039","type":"journal-article","created":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T19:42:30Z","timestamp":1626982950000},"page":"105039","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Performance on a modified signal detection task of attention is impaired in male and female rats following developmental exposure to the synthetic progestin, 17\u03b1-hydroxyprogesterone caproate"],"prefix":"10.1016","volume":"135","author":[{"given":"Melanie","family":"Lolier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roy O.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth I.","family":"Wood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine K.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.yhbeh.2021.105039_bb0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajog.2007.05.024","article-title":"Comparison of progesterone and glucocorticoid receptor binding and stimulation of gene expression by progesterone, 17-alpha hydroxyprogesterone caproate, and related progestins","volume":"197","author":"Attardi","year":"2007","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0010","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.bbr.2012.07.028","article-title":"Sex differences in attentional processes in adult rats as measured by performance on the 5-choice serial reaction time task","volume":"235","author":"Bayless","year":"2012","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0015","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.ajog.2012.03.010","article-title":"Progesterone and preterm birth prevention: translating clinical trials data into clinical practice","volume":"206","author":"Berghella","year":"2012","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0020","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0163-1047(86)90794-6","article-title":"Preserved spatial memory in old rats survives 10 months without training","volume":"45","author":"Bierley","year":"1986","journal-title":"Behav. Neural Biol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0025","doi-asserted-by":"crossref","first-page":"4320","DOI":"10.1523\/JNEUROSCI.20-11-04320.2000","article-title":"Medial frontal cortex mediates perceptual attentional set shifting in the rat","volume":"20","author":"Birrell","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0030","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bbr.2013.04.037","article-title":"Neural structures underlying set-shifting: roles of medial prefrontal cortex and anterior cingulate cortex","volume":"250","author":"Bissonette","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0035","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1007\/s002130000536","article-title":"The effects of d-amphetamine, chlordiazepoxide, a-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement in rats","volume":"152","author":"Cardinal","year":"2000","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.yhbeh.2021.105039_bb0040","doi-asserted-by":"crossref","first-page":"398.e1","DOI":"10.1016\/j.ajog.2012.08.015","article-title":"Pharmacology and placental transport of 17-hydroxyprogesterone caproate in singleton gestation","volume":"207","author":"Caritis","year":"2012","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnsys.2014.00160","article-title":"From attention to memory along the dorsal-ventral axis of the medial prefrontal cortex: some methodological considerations","volume":"8","author":"Cassaday","year":"2014","journal-title":"Front. Syst. Neurosci."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0050","first-page":"711","article-title":"Dopaminergic modulation of reward discounting: a systematic review and meta-analysis","author":"Castrellon","year":"2020","journal-title":"bioRxiv"},{"key":"10.1016\/j.yhbeh.2021.105039_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci10050292","article-title":"Attention-deficit\/hyperactivity disorder predominantly inattentive subtype\/presentation: research progress and translational studies","volume":"10","author":"De La Pe\u00f1a","year":"2020","journal-title":"Brain Sci."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0060","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S0140-6736(05)63326-0","article-title":"Low medial prefrontal dopaminergic activity in autistic children","volume":"350","author":"Ernst","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.yhbeh.2021.105039_bb0065","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.nlm.2007.10.007","article-title":"Differential effects of inactivation of the orbitofrontal cortex on strategy set-shifting and reversal learning","volume":"89","author":"Ghods-Sharifi","year":"2008","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0070","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1523\/JNEUROSCI.20-03-01208.2000","article-title":"Enhanced and impaired attentional performance after infusion of D1 dopaminergic receptor agents into rat prefrontal cortex","volume":"20","author":"Granon","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0075","doi-asserted-by":"crossref","first-page":"169.e1","DOI":"10.1016\/j.ajog.2007.11.065","article-title":"Transplacental transfer and metabolism of 17-alpha-hydroxyprogesterone caproate","volume":"199","author":"Hemauer","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0080","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1037\/0735-7044.117.1.76","article-title":"Sex-related differences in spatial divided attention and motor impulsivity in rats","volume":"117","author":"Jentsch","year":"2003","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyg.2013.00863","article-title":"Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs","volume":"4","author":"Lakens","year":"2013","journal-title":"Front. Psychol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0090","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12962","article-title":"Sex differences in dopamine innervation and microglia are altered by synthetic progestin in neonatal medial prefrontal cortex","volume":"33","author":"Lolier","year":"2021","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0095","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/11250008809386764","article-title":"Wistar rats retain for months memory of active avoidance learned behaviour","volume":"65","author":"Mariucci","year":"1998","journal-title":"Ital. J. Zool."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0100","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.bbr.2003.09.019","article-title":"Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat","volume":"146","author":"McAlonan","year":"2003","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0105","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1056\/NEJMoa035140","article-title":"Prevention of recurrent preterm delivery by 17 alpha-hydroxyprogesterone caproate","volume":"348","author":"Meis","year":"2003","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0110","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1097\/01.AOG.0000281348.51499.bc","article-title":"Follow-up of children exposed in utero to 17 alpha-hydroxyprogesterone caproate compared with placebo","volume":"110","author":"Northen","year":"2007","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0115","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1007\/s10548-017-0545-3","article-title":"Missing the target: the neural processing underlying the omission error","volume":"30","author":"Perri","year":"2017","journal-title":"Brain Topogr."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyt.2015.00122","article-title":"Attentional profiles and white matter correlates in attention-deficit\/hyperactivity disorder predominantly inattentive type","volume":"6","author":"Rossi","year":"2015","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.yhbeh.2021.105039_bb0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/jne.12862","article-title":"Developmental exposure to 17a-hydroxyprogesterone caproate impairs adult delayed reinforcement and reversal learning in male and female rats","volume":"32","author":"Serpa","year":"2020","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0130","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.bbr.2003.09.015","article-title":"What the rodent prefrontal cortex can teach us about attention-deficit\/ hyperactivity disorder: the critical role of early developmental events on prefrontal function","volume":"146","author":"Sullivan","year":"2003","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0135","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1006\/nlme.2001.4024","article-title":"Comparison of single unit responses to tone, light, and compound conditioned stimuli during rabbit classical eyeblink conditioning","volume":"76","author":"Tracy","year":"2001","journal-title":"Neurobiol. Learn. Mem."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fnbeh.2015.00370","article-title":"Measuring attention in rodents: comparison of a modified signal detection task and the 5-choice serial reaction time task","volume":"9","author":"Turner","year":"2016","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0145","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00213-006-0396-1","article-title":"Behavioral disinhibition requires dopamine receptor activation","volume":"187","author":"Van Gaalen","year":"2006","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.yhbeh.2021.105039_bb0150","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/cne.903360303","article-title":"Immunocytochemical evidence of well-developed dopaminergic and noradrenergic innervations in the frontal cerebral cortex of human fetuses at midgestation","volume":"336","author":"Verney","year":"1993","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0155","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.euroneuro.2015.01.002","article-title":"Anabolic-androgenic steroids impair set-shifting and reversal learning in male rats","volume":"25","author":"Wallin","year":"2015","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.yhbeh.2021.105039_bb0160","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1159\/000434725","article-title":"Progesterone receptor expression in the developing mesocortical dopamine pathway: importance for complex cognitive behavior in adulthood","volume":"103","author":"Willing","year":"2016","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.yhbeh.2021.105039_bb0165","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1210\/en.2015-1775","article-title":"Exposure to the synthetic progestin, 17a-hydroxyprogesterone caproate during development impairs cognitive flexibility in adulthood","volume":"157","author":"Willing","year":"2016","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2021.105039_bb0170","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1111\/j.1476-5381.2011.01323.x","article-title":"The utility of rat models of impulsivity in developing pharmacotherapies for impulse control disorders","volume":"164","author":"Winstanley","year":"2011","journal-title":"Br. J. Pharmacol."}],"container-title":["Hormones and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X21001185?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X21001185?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T00:42:57Z","timestamp":1758069777000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0018506X21001185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":34,"alternative-id":["S0018506X21001185"],"URL":"https:\/\/doi.org\/10.1016\/j.yhbeh.2021.105039","relation":{},"ISSN":["0018-506X"],"issn-type":[{"type":"print","value":"0018-506X"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Performance on a modified signal detection task of attention is impaired in male and female rats following developmental exposure to the synthetic progestin, 17\u03b1-hydroxyprogesterone caproate","name":"articletitle","label":"Article Title"},{"value":"Hormones and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yhbeh.2021.105039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105039"}}