{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T21:28:14Z","timestamp":1773955694357,"version":"3.50.1"},"reference-count":98,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100009790","name":"University at Albany","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009790","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01-MH112768"],"award-info":[{"award-number":["R01-MH112768"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R15-MH118692"],"award-info":[{"award-number":["R15-MH118692"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Hormones and Behavior"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.yhbeh.2021.105044","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T05:54:27Z","timestamp":1631080467000},"page":"105044","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Alterations in corticotropin-releasing factor receptor type 1 in the preoptic area and hypothalamus in mice during the postpartum period"],"prefix":"10.1016","volume":"135","author":[{"given":"Rose M.","family":"De Guzman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary J.","family":"Rosinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine E.","family":"Parra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason S.","family":"Jacobskind","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas J.","family":"Justice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damian G.","family":"Zuloaga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.yhbeh.2021.105044_bb0005","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1007\/s00737-014-0491-y","article-title":"Maternal anxiety from pregnancy to 2 years postpartum: transactional patterns of maternal early adversity and child temperament","volume":"18","author":"Agrati","year":"2015","journal-title":"Arch. Womens Ment. Health"},{"issue":"10","key":"10.1016\/j.yhbeh.2021.105044_bb0010","first-page":"2954","article-title":"Suppression of hypothalmic-pituitary-adrenal axis responses to stress in lactating women","volume":"80","author":"Altemus","year":"1995","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0015","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1469-7610.1991.tb00321.x","article-title":"Maternal anxiety: a 5-year review of an intervention study","volume":"32","author":"Barnett","year":"1991","journal-title":"J. Child Psychol. Psychiatry"},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb0020","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/cne.1325","article-title":"Suckling stimulus suppresses messenger RNA for tyrosine hydroxylase in arcuate neurons during lactation","volume":"438","author":"Berghorn","year":"2001","journal-title":"J. Comp. Neurol."},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0025","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/GRF.0b013e3181b52930","article-title":"Impact of antenatal and postpartum maternal mental illness: how are the children?","volume":"52","author":"Brand","year":"2009","journal-title":"Clin. Obstet. Gynecol."},{"issue":"12","key":"10.1016\/j.yhbeh.2021.105044_bb0030","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1111\/jne.12223","article-title":"Prolactin regulation of kisspeptin neurones in the mouse brain and its role in the lactation-induced suppression of kisspeptin expression","volume":"26","author":"Brown","year":"2014","journal-title":"J. Neuroendocrinol."},{"issue":"9","key":"10.1016\/j.yhbeh.2021.105044_bb0035","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1111\/jne.12297","article-title":"Effects of prolactin and lactation on A15 dopamine neurones in the rostral preoptic area of female mice","volume":"27","author":"Brown","year":"2015","journal-title":"J. Neuroendocrinol."},{"issue":"19","key":"10.1016\/j.yhbeh.2021.105044_bb0040","doi-asserted-by":"crossref","first-page":"8967","DOI":"10.1073\/pnas.90.19.8967","article-title":"Expression cloning of a human corticotropin-releasing-factor receptor","volume":"90","author":"Chen","year":"1993","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0045","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1177\/1524838015584369","article-title":"Childhood maltreatment and perinatal mood and anxiety disorders: a systematic review","volume":"17","author":"Choi","year":"2016","journal-title":"Trauma Violence Abuse"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0196-9781(85)90128-7","article-title":"Anatomy and physiology of the neuroendocrine arcuate nucleus","volume":"6","author":"Chronwall","year":"1985","journal-title":"Peptides"},{"issue":"7","key":"10.1016\/j.yhbeh.2021.105044_bb0055","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1038\/nrendo.2009.106","article-title":"Stress and disorders of the stress system","volume":"5","author":"Chrousos","year":"2009","journal-title":"Nat. Rev. Endocrinol."},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb0060","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.pbb.2010.06.012","article-title":"Forced swim test behavior in postpartum rats","volume":"96","author":"Craft","year":"2010","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0065","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.jad.2016.08.008","article-title":"Effects of corticotropin-releasing hormone receptor 1 SNPs on major depressive disorder are influenced by sex and smoking status","volume":"205","author":"da Silva","year":"2016","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0070","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2010.12.017","article-title":"Tyrosine hydroxylase and regulation of dopamine synthesis","volume":"508","author":"Daubner","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0075","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.bbr.2018.07.012","article-title":"High nursing demand reduces depression-like behavior despite increasing glucocorticoid concentrations and reducing hippocampal neurogenesis in late postpartum rats","volume":"353","author":"De Guzman","year":"2018","journal-title":"Behav. Brain Res."},{"issue":"10","key":"10.1016\/j.yhbeh.2021.105044_bb0080","doi-asserted-by":"crossref","first-page":"3807","DOI":"10.1210\/en.2012-2136","article-title":"Estrogen, predominantly via estrogen receptor a, attenuates postpartum-induced anxiety- and depression-like behaviors in female rats","volume":"154","author":"Furuta","year":"2013","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/ncomms11937","article-title":"Hypothalamic CRH neurons orchestrate complex behaviours after stress","volume":"7","author":"F\u00fczesi","year":"2016","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0090","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1471-2202-8-17","article-title":"Altered maternal profiles in corticotropin-releasing factor receptor 1 deficient mice","volume":"8","author":"Gammie","year":"2007","journal-title":"BMC Neurosci."},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0095","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.neuroscience.2008.09.026","article-title":"Deletion of corticotropin-releasing factor binding protein selectively impairs maternal, but not intermale aggression","volume":"157","author":"Gammie","year":"2008","journal-title":"Neuroscience"},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb0100","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0121125","article-title":"Sex differences between CRF1 receptor deficient mice following naloxone-precipitated morphine withdrawal in a conditioned place aversion paradigm: implication of HPA axis","volume":"10","author":"Garc\u00eda-Carmona","year":"2015","journal-title":"PLoS One"},{"issue":"5 Part 1","key":"10.1016\/j.yhbeh.2021.105044_bb0105","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1097\/01.AOG.0000183597.31630.db","article-title":"Perinatal depression: a systematic review of prevalence and incidence","volume":"106","author":"Gavin","year":"2005","journal-title":"Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.yhbeh.2021.105044_bb0110","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00213-010-2089-z","article-title":"Functional topography of midbrain and pontine serotonergic systems: implications for synaptic regulation of serotonergic circuits","volume":"213","author":"Hale","year":"2011","journal-title":"Psychopharmacology"},{"issue":"10","key":"10.1016\/j.yhbeh.2021.105044_bb0115","doi-asserted-by":"crossref","first-page":"4798","DOI":"10.1210\/jcem.86.10.7919","article-title":"Effects of suckling on hypothalamic-pituitary-adrenal axis responses to psychosocial stress in postpartum lactating women","volume":"86","author":"Heinrichs","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.yhbeh.2021.105044_bb0120","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.brainresrev.2007.05.006","article-title":"Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V)","volume":"57","author":"Herbison","year":"2008","journal-title":"Brain Res. Rev."},{"issue":"14","key":"10.1016\/j.yhbeh.2021.105044_bb0125","doi-asserted-by":"crossref","first-page":"4093","DOI":"10.1523\/JNEUROSCI.2232-15.2016","article-title":"Episodic social stress-escalated cocaine self-administration: role of phasic and tonic corticotropin releasing factor in the anterior and posterior ventral tegmental area","volume":"36","author":"Holly","year":"2016","journal-title":"J. Neurosci."},{"issue":"11","key":"10.1016\/j.yhbeh.2021.105044_bb0130","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.biopsych.2013.10.013","article-title":"Sex differences in corticotropin-releasing factor receptor-1 action within the dorsal raphe nucleus in stress responsivity","volume":"75","author":"Howerton","year":"2014","journal-title":"Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0135","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/adb.12189","article-title":"Dissociation of \u00b5-opioid receptor and CRF-R1 antagonist effects on escalated ethanol consumption and mPFC serotonin in C57BL\/6J mice","volume":"21","author":"Hwa","year":"2016","journal-title":"Addict. Biol."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0140","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/0169-328X(96)00011-3","article-title":"Corticotropin-releasing factor up-regulates its own receptor mRNA in the paraventricular nucleus of the hypothalamus","volume":"38","author":"Imaki","year":"1996","journal-title":"Mol. Brain Res."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0145","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.brainres.2017.09.020","article-title":"Hypothalamic-pituitary-adrenal axis responsiveness to methamphetamine is modulated by gonadectomy in males","volume":"1677","author":"Jacobskind","year":"2017","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0150","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.bbr.2019.03.034","article-title":"Stress-induced neural activation is altered during early withdrawal from chronic methamphetamine","volume":"366","author":"Jacobskind","year":"2019","journal-title":"Behav. Brain Res."},{"issue":"8","key":"10.1016\/j.yhbeh.2021.105044_bb0155","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1523\/JNEUROSCI.1492-17.2017","article-title":"Local corticotropin-releasing factor signaling in the hypothalamic paraventricular nucleus","volume":"38","author":"Jiang","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2019.100192","article-title":"CRF signaling between neurons in the paraventricular nucleus of the hypothalamus (PVN) coordinates stress responses","volume":"11","author":"Jiang","year":"2019","journal-title":"Neurobiol. Stress"},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb0165","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/cne.21848","article-title":"Type 1 corticotropin-releasing factor receptor expression reported in BAC transgenic mice: implications for reconciling ligand-receptor mismatch in the central corticotropin-releasing factor system","volume":"511","author":"Justice","year":"2008","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.yfrne.2019.01.001","article-title":"Mom doesn\u2019t care: when increased brain CRF system activity leads to maternal neglect in rodents","volume":"53","author":"Klampfl","year":"2019","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0175","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.psyneuen.2015.11.015","article-title":"CRF-R1 activation in the anterior-dorsal BNST induces maternal neglect in lactating rats via an HPA axis-independent central mechanism","volume":"64","author":"Klampfl","year":"2016","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0180","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.neuropharm.2018.02.019","article-title":"Maternal stress and the MPOA: activation of CRF receptor 1 impairs maternal behavior and triggers local oxytocin release in lactating rats","volume":"133","author":"Klampfl","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0185","series-title":"Parental Care in Mammals","first-page":"347","article-title":"The evolution of male parental investment in mammals","author":"Kleiman","year":"1981"},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0190","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.neuron.2011.11.030","article-title":"Evoked axonal oxytocin release in the central amygdala attenuates fear response","volume":"73","author":"Knobloch","year":"2012","journal-title":"Neuron"},{"issue":"9","key":"10.1016\/j.yhbeh.2021.105044_bb0195","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12634","article-title":"Analysis of prolactin receptor expression in the murine brain using a novel prolactin receptor reporter mouse","volume":"30","author":"Kokay","year":"2018","journal-title":"J. Neuroendocrinol."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0200","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/npp.2009.110","article-title":"Neurocircuitry of addiction","volume":"35","author":"Koob","year":"2010","journal-title":"Neuropsychopharmacology"},{"issue":"5","key":"10.1016\/j.yhbeh.2021.105044_bb0205","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.pnpbp.2011.02.008","article-title":"Neuromolecular basis of parental behavior in laboratory mice and rats: with special emphasis on technical issues of using mouse genetics","volume":"35","author":"Kuroda","year":"2011","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb0210","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/j.neuroscience.2006.07.027","article-title":"The effect of single or repeated restraint stress on several signal molecules in paraventricular nucleus, arcuate nucleus and locus coeruleus","volume":"142","author":"Kwon","year":"2006","journal-title":"Neuroscience"},{"issue":"7124","key":"10.1016\/j.yhbeh.2021.105044_bb0215","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nature05453","article-title":"Genome-wide atlas of gene expression in the adult mouse brain","volume":"445","author":"Lein","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0220","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/(SICI)1096-9861(19960101)364:1<151::AID-CNE12>3.0.CO;2-1","article-title":"Immunocytochemical distribution of catecholamine-synthesizing neurons in the hypothalamus and pituitary gland of pigs: tyrosine hydroxylase and dopamine-beta-hydroxylase","volume":"364","author":"Leshin","year":"1996","journal-title":"J. Comp. Neurol."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0225","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s00213-020-05652-3","article-title":"CRF-5-HT interactions in the dorsal raphe nucleus and motivation for stress-induced opioid reinstatement","volume":"238","author":"Li","year":"2021","journal-title":"Psychopharmacology"},{"issue":"5","key":"10.1016\/j.yhbeh.2021.105044_bb0230","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1210\/endo-124-5-2358","article-title":"Lactation inhibits stress-mediated secretion of corticosterone and oxytocin and hypothalamic accumulation of corticotropin-releasing factor and enkephalin messenger ribonucleic acids","volume":"124","author":"Lightman","year":"1989","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0235","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.neuron.2020.02.009","article-title":"The raphe dopamine system controls the expression of incentive memory","volume":"106","author":"Lin","year":"2020","journal-title":"Neuron"},{"issue":"5","key":"10.1016\/j.yhbeh.2021.105044_bb0240","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.tins.2021.01.002","article-title":"The raphe dopamine system: roles in salience encoding, memory expression, and addiction","volume":"44","author":"Lin","year":"2021","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0245","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1210\/en.2013-1621","article-title":"Lactational anovulation in mice results from a selective loss of kisspeptin input to GnRH neurons","volume":"155","author":"Liu","year":"2014","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0250","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.pbb.2013.06.011","article-title":"Oxytocin, motivation and the role of dopamine","volume":"119","author":"Love","year":"2014","journal-title":"Pharmacol. Biochem. Behav."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb9000","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1210\/en.2004-0800","article-title":"Prolactin-regulated tyrosine hydroxylase activity and messenger ribonucleic acid expression in mediobasal hypothalamic cultures: the differential role of specific protein kinases","volume":"146","author":"Ma","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0255","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.yhbeh.2018.02.011","article-title":"Histone deacetylase inhibitor treatment induces postpartum-like maternal behavior and immediate early gene expression in the maternal neural pathway in virgin mice","volume":"108","author":"Mayer","year":"2019","journal-title":"Horm. Behav."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0260","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.psyneuen.2017.12.003","article-title":"Inability to suppress the stress-induced activation of the HPA axis during the peripartum period engenders deficits in postpartum behaviors in mice","volume":"90","author":"Mel\u00f3n","year":"2018","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0265","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3389\/fpsyt.2019.00101","article-title":"Is the HPA axis as target for depression outdated, or is there a new hope?","volume":"10","author":"Menke","year":"2019","journal-title":"Front. Psych."},{"issue":"5","key":"10.1016\/j.yhbeh.2021.105044_bb0270","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0306-4530(01)00007-5","article-title":"Antidepressant-like actions of pregnancy, and progesterone in wistar rats forced to swim","volume":"26","author":"Molina-Hern\u00e1ndez","year":"2001","journal-title":"Psychoneuroendocrinology"},{"issue":"9","key":"10.1016\/j.yhbeh.2021.105044_bb0275","doi-asserted-by":"crossref","first-page":"2910","DOI":"10.1016\/S0021-9258(18)93832-9","article-title":"Tyrosine hydroxylase: the initial step in norepinephrine biosynthesis","volume":"239","author":"Nagatsu","year":"1964","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.yhbeh.2021.105044_bb0280","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1002\/cne.24857","article-title":"Distributions of hypothalamic neuron populations coexpressing tyrosine hydroxylase and the vesicular GABA transporter in the mouse","volume":"528","author":"Negishi","year":"2020","journal-title":"J. Comp. Neurol."},{"issue":"5","key":"10.1016\/j.yhbeh.2021.105044_bb0285","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0306-4530(98)00023-7","article-title":"Increased basal activity of the hypothalamo\u2013pituitary\u2013adrenal axis during pregnancy in rats bred for high anxiety-related behaviour","volume":"23","author":"Neumann","year":"1998","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0290","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/dev.20198","article-title":"Motivational systems and the neural circuitry of maternal behavior in the rat","volume":"49","author":"Numan","year":"2007","journal-title":"Dev. Psychobiol."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0295","first-page":"246","article-title":"Paternal behavior","author":"Numan","year":"2003","journal-title":"Neurobiol. Parental Behav."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0300","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.yfrne.2008.10.002","article-title":"Medial preoptic area interactions with dopamine neural systems in the control of the onset and maintenance of maternal behavior in rats","volume":"30","author":"Numan","year":"2009","journal-title":"Front. Neuroendocrinol."},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb9010","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1037\/a0016204","article-title":"Temporary inactivation of ventral tegmental area neurons with either muscimol or baclofen reversibly disrupts maternal behavior in rats through different underlying mechanisms","volume":"123","author":"Numan","year":"2009","journal-title":"Behav Neurosci."},{"issue":"12","key":"10.1016\/j.yhbeh.2021.105044_bb0305","doi-asserted-by":"crossref","first-page":"2148","DOI":"10.1038\/sj.npp.1300267","article-title":"Altered serotonergic neurotransmission but normal hypothalamic\u2013pituitary\u2013adrenocortical axis activity in mice chronically treated with the corticotropin-releasing hormone receptor type 1 antagonist NBI 30775","volume":"28","author":"Oshima","year":"2003","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0310","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/0006-8993(82)90660-6","article-title":"Selective depletion of somatostatin in rat brain by cysteamine","volume":"240","author":"Palkovits","year":"1982","journal-title":"Brain Res."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0315","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.bbr.2017.02.047","article-title":"Maternal care associates with differences in morphological complexity in the medial preoptic area","volume":"326","author":"Parent","year":"2017","journal-title":"Behav. Brain Res."},{"issue":"21","key":"10.1016\/j.yhbeh.2021.105044_bb0320","doi-asserted-by":"crossref","first-page":"7077","DOI":"10.1523\/JNEUROSCI.16-21-07077.1996","article-title":"Gonadal steroids exert facilitating and \u201cbuffering\u201d effects on glucocorticoid-mediated transcriptional regulation of corticotropin-releasing hormone and corticosteroid receptor genes in rat brain","volume":"16","author":"Patchev","year":"1996","journal-title":"J. Neurosci."},{"issue":"6","key":"10.1016\/j.yhbeh.2021.105044_bb9020","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/S0893-133X(97)00197-8","article-title":"Effects of corticotropin-releasing factor on brain serotonergic activity","volume":"18","author":"Price","year":"1998","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0330","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/nn.4491","article-title":"Hypothalamic CRFR1 is essential for HPA axis regulation following chronic stress","volume":"20","author":"Ramot","year":"2017","journal-title":"Nat. Neurosci."},{"issue":"6051","key":"10.1016\/j.yhbeh.2021.105044_bb0335","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1126\/science.1202107","article-title":"Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1","volume":"333","author":"Refojo","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0340","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.neuroscience.2017.08.016","article-title":"Distribution of corticotropin-releasing factor receptor 1 in the developing mouse forebrain: a novel sex difference revealed in the rostral periventricular hypothalamus","volume":"361","author":"Rosinger","year":"2017","journal-title":"Neuroscience"},{"issue":"6","key":"10.1016\/j.yhbeh.2021.105044_bb0345","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1002\/cne.24588","article-title":"Characterization and gonadal hormone regulation of a sexually dimorphic corticotropin-releasing factor receptor 1 cell group","volume":"527","author":"Rosinger","year":"2019","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0350","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.neuroscience.2019.04.045","article-title":"A sexually dimorphic distribution of corticotropin-releasing factor receptor 1 in the paraventricular hypothalamus","volume":"409","author":"Rosinger","year":"2019","journal-title":"Neuroscience"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0355","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.112847","article-title":"Sex-dependent effects of chronic variable stress on discrete corticotropin-releasing factor receptor 1 cell populations","volume":"219","author":"Rosinger","year":"2020","journal-title":"Physiol. Behav."},{"issue":"4639","key":"10.1016\/j.yhbeh.2021.105044_bb0360","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1126\/science.6141639","article-title":"Estradiol is concentrated in tyrosine hydroxylase-containing neurons of the hypothalamus","volume":"223","author":"Sar","year":"1984","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0365","first-page":"69","article-title":"Ovariectomy alters gene expression of the hippocampal formation in middle-aged rats","volume":"158","author":"S\u00e1rv\u00e1ri","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0370","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/j.psyneuen.2016.09.015","article-title":"Corticotropin-releasing hormone induces depression-like changes of sleep electroencephalogram in healthy women","volume":"74","author":"Sch\u00fcssler","year":"2016","journal-title":"Psychoneuroendocrinology"},{"issue":"7570","key":"10.1016\/j.yhbeh.2021.105044_bb0375","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nature15378","article-title":"A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion","volume":"525","author":"Scott","year":"2015","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.yhbeh.2021.105044_bb0380","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1037\/a0017666","article-title":"Transient inactivation of the ventral tegmental area selectively disrupts the expression of conditioned place preference for pup-but not cocaine-paired contexts","volume":"123","author":"Seip","year":"2009","journal-title":"Behav. Neurosci."},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0385","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13041-019-0490-z","article-title":"Increased depression-related behavior during the postpartum period in inbred BALB\/c and C57BL\/6 strains","volume":"12","author":"Shoji","year":"2019","journal-title":"Mol. Brain"},{"issue":"1","key":"10.1016\/j.yhbeh.2021.105044_bb0390","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1146\/annurev.neuro.25.112701.142745","article-title":"Wired for reproduction: organization and development of sexually dimorphic circuits in the mammalian forebrain","volume":"25","author":"Simerly","year":"2002","journal-title":"Annu. Rev. Neurosci."},{"issue":"25","key":"10.1016\/j.yhbeh.2021.105044_bb0395","doi-asserted-by":"crossref","first-page":"14077","DOI":"10.1073\/pnas.94.25.14077","article-title":"Estrogen receptor-dependent sexual differentiation of dopaminergic neurons in the preoptic region of the mouse","volume":"94","author":"Simerly","year":"1997","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"6","key":"10.1016\/j.yhbeh.2021.105044_bb0400","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0896-6273(00)80491-2","article-title":"Corticotropin releasing factor receptor 1\u2013deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development","volume":"20","author":"Smith","year":"1998","journal-title":"Neuron"},{"issue":"6","key":"10.1016\/j.yhbeh.2021.105044_bb0405","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1523\/JNEUROSCI.5562-08.2009","article-title":"Synaptic overflow of dopamine in the nucleus accumbens arises from neuronal activity in the ventral tegmental area","volume":"29","author":"Sombers","year":"2009","journal-title":"J. Neurosci."},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0410","first-page":"301","article-title":"Perinatal mood disorders: position paper","volume":"34","author":"Steiner","year":"1998","journal-title":"Psychopharmacol. Bull."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0415","doi-asserted-by":"crossref","DOI":"10.1016\/j.yfrne.2019.04.002","article-title":"Experience-dependent mechanisms in the regulation of parental care","volume":"54","author":"Stolzenberg","year":"2019","journal-title":"Front. Neuroendocrinol."},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb0420","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1002\/cne.901630406","article-title":"The central adrenergic system. an immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-beta-hydroxylase as a marker","volume":"163","author":"Swanson","year":"1975","journal-title":"J. Comp. Neurol."},{"issue":"6","key":"10.1016\/j.yhbeh.2021.105044_bb0425","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1159\/000123111","article-title":"Paraventricular nucleus: a site for the integration of neuroendocrine and autonomic mechanisms","volume":"31","author":"Swanson","year":"1980","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0430","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s00737-014-0423-x","article-title":"Maternal bonding in mothers with postpartum anxiety disorder: the crucial role of subclinical depressive symptoms and maternal avoidance behaviour","volume":"17","author":"Tietz","year":"2014","journal-title":"Arch. Womens Ment. Health"},{"key":"10.1016\/j.yhbeh.2021.105044_bb0435","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1126\/science.6267699","article-title":"Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and \u00df-endorphin","author":"Vale","year":"1981","journal-title":"Science"},{"issue":"4","key":"10.1016\/j.yhbeh.2021.105044_bb0440","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1002\/cne.1043","article-title":"Evidence for regional heterogeneity in corticotropin-releasing factor interactions in the dorsal raphe nucleus","volume":"435","author":"Valentino","year":"2001","journal-title":"J. Comp. Neurol."},{"issue":"2","key":"10.1016\/j.yhbeh.2021.105044_bb0445","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/1096-9861(20001211)428:2<191::AID-CNE1>3.0.CO;2-U","article-title":"Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse","volume":"428","author":"Van Pett","year":"2000","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.yhbeh.2021.105044_bb0450","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2019.111981","article-title":"Anxiety-like behavior induced by 6-OHDA animal model of Parkinson's disease may be related to a dysregulation of neurotransmitter systems in brain areas related to anxiety","volume":"371","author":"Vieira","year":"2019","journal-title":"Behav. Brain Res."},{"issue":"8","key":"10.1016\/j.yhbeh.2021.105044_bb0455","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1365-2826.1995.tb00799.x","article-title":"Dissociation between behavioral and hormonal responses to the forced swim stress in lactating rats","volume":"7","author":"Walker","year":"1995","journal-title":"J. Neuroendocrinol."},{"issue":"3\u20134","key":"10.1016\/j.yhbeh.2021.105044_bb0460","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000503006","article-title":"Differential roles of hypothalamic AVPV and arcuate kisspeptin neurons in estradiol feedback regulation of female reproduction","volume":"110","author":"Wang","year":"2020","journal-title":"Neuroendocrinology"},{"issue":"5","key":"10.1016\/j.yhbeh.2021.105044_bb0465","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/mp.2016.136","article-title":"Loss of hypothalamic corticotropin-releasing hormone markedly reduces anxiety behaviors in mice","volume":"22","author":"Zhang","year":"2017","journal-title":"Mol. Psychiatry"},{"issue":"3","key":"10.1016\/j.yhbeh.2021.105044_bb0470","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0022-3956(00)00016-9","article-title":"Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated","volume":"34","author":"Zobel","year":"2000","journal-title":"J. Psychiatr. Res."},{"issue":"2","key":"10.1016\/j.yhbeh.2021.105044_bb0475","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.yhbeh.2006.10.003","article-title":"Androgen-sensitivity of somata and dendrites of spinal nucleus of the bulbocavernosus (SNB) motoneurons in male C57BL6J mice","volume":"51","author":"Zuloaga","year":"2007","journal-title":"Horm. Behav."},{"issue":"2","key":"10.1016\/j.yhbeh.2021.105044_bb0480","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/cne.23400","article-title":"Estrogen receptor \u00df expression in the mouse forebrain: age and sex differences","volume":"522","author":"Zuloaga","year":"2014","journal-title":"J. Comp. Neurol."}],"container-title":["Hormones and Behavior"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X21001239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0018506X21001239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T12:41:59Z","timestamp":1762173719000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0018506X21001239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":98,"alternative-id":["S0018506X21001239"],"URL":"https:\/\/doi.org\/10.1016\/j.yhbeh.2021.105044","relation":{},"ISSN":["0018-506X"],"issn-type":[{"value":"0018-506X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alterations in corticotropin-releasing factor receptor type 1 in the preoptic area and hypothalamus in mice during the postpartum period","name":"articletitle","label":"Article Title"},{"value":"Hormones and Behavior","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yhbeh.2021.105044","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105044"}}