{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:23:51Z","timestamp":1761960231249,"version":"build-2065373602"},"reference-count":14,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,2,1]],"date-time":"2010-02-01T00:00:00Z","timestamp":1264982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2010,2]]},"DOI":"10.1016\/j.yjmcc.2009.10.015","type":"journal-article","created":{"date-parts":[[2009,10,30]],"date-time":"2009-10-30T04:17:10Z","timestamp":1256876230000},"page":"277-278","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Actin in action and inaction: The differential effects of hypertrophic and dilated cardiomyopathy actin mutations on thin filament regulation"],"prefix":"10.1016","volume":"48","author":[{"given":"Michael J.","family":"Greenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey R.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.yjmcc.2009.10.015_bib1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1111\/j.1540-8167.2007.00965.x","article-title":"Genetic basis of hypertrophic cardiomyopathy: from bench to the clinics","volume":"19","author":"Alcalai","year":"2008","journal-title":"J. Cardiovasc. Electrophysiol."},{"issue":"2","key":"10.1016\/j.yjmcc.2009.10.015_bib2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1086\/321978","article-title":"Many roads lead to a broken heart: the genetics of dilated cardiomyopathy","volume":"69","author":"Schonberger","year":"2001","journal-title":"Am. J. Hum. Genet."},{"issue":"24","key":"10.1016\/j.yjmcc.2009.10.015_bib3","doi-asserted-by":"crossref","first-page":"16777","DOI":"10.1074\/jbc.M512935200","article-title":"Functional consequences of a mutation in an expressed human alpha-cardiac actin at a site implicated in familial hypertrophic cardiomyopathy","volume":"281","author":"Bookwalter","year":"2006","journal-title":"J. Biol. Chem."},{"issue":"5364","key":"10.1016\/j.yjmcc.2009.10.015_bib4","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1126\/science.280.5364.750","article-title":"Actin mutations in dilated cardiomyopathy, a heritable form of heart failure","volume":"280","author":"Olson","year":"1998","journal-title":"Science (New York, NY"},{"issue":"9","key":"10.1016\/j.yjmcc.2009.10.015_bib5","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1006\/jmcc.2000.1204","article-title":"Inherited and de novo mutations in the cardiac actin gene cause hypertrophic cardiomyopathy","volume":"32","author":"Olson","year":"2000","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"2","key":"10.1016\/j.yjmcc.2009.10.015_bib6","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1152\/physrev.2000.80.2.853","article-title":"Regulation of contraction in striated muscle","volume":"80","author":"Gordon","year":"2000","journal-title":"Physiol. Rev."},{"issue":"1","key":"10.1016\/j.yjmcc.2009.10.015_bib7","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1006\/jmbi.1996.0800","article-title":"Steric-model for activation of muscle thin filaments","volume":"266","author":"Vibert","year":"1997","journal-title":"J. Mol. Biol."},{"issue":"2","key":"10.1016\/j.yjmcc.2009.10.015_bib8","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S0006-3495(93)81110-X","article-title":"Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament","volume":"65","author":"McKillop","year":"1993","journal-title":"Biophys. J."},{"issue":"4","key":"10.1016\/j.yjmcc.2009.10.015_bib9","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1016\/S0006-3495(03)74671-2","article-title":"Activation of the calcium-regulated thin filament by myosin strong binding","volume":"85","author":"Gorga","year":"2003","journal-title":"Biophys. J."},{"issue":"17","key":"10.1016\/j.yjmcc.2009.10.015_bib10","doi-asserted-by":"crossref","first-page":"6272","DOI":"10.1073\/pnas.83.17.6272","article-title":"Fluorescent actin filaments move on myosin fixed to a glass surface","volume":"83","author":"Kron","year":"1986","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"6467","key":"10.1016\/j.yjmcc.2009.10.015_bib11","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/368113a0","article-title":"Single myosin molecule mechanics: piconewton forces and nanometre steps","volume":"368","author":"Finer","year":"1994","journal-title":"Nature"},{"issue":"47","key":"10.1016\/j.yjmcc.2009.10.015_bib12","doi-asserted-by":"crossref","first-page":"16990","DOI":"10.1073\/pnas.0506326102","article-title":"Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin","volume":"102","author":"Kad","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S. A."},{"issue":"1","key":"10.1016\/j.yjmcc.2009.10.015_bib13","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1006\/jmbi.1994.0070","article-title":"An atomic model of the unregulated thin filament obtained by X-ray fiber diffraction on oriented actin-tropomyosin gels","volume":"246","author":"Lorenz","year":"1995","journal-title":"J. Mol. Biol."},{"issue":"2","key":"10.1016\/j.yjmcc.2009.10.015_bib14","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jsb.2006.02.020","article-title":"A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle","volume":"155","author":"Poole","year":"2006","journal-title":"J. Struct. Biol."}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002228280900457X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002228280900457X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T20:17:49Z","timestamp":1758313069000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002228280900457X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,2]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,2]]}},"alternative-id":["S002228280900457X"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2009.10.015","relation":{},"ISSN":["0022-2828"],"issn-type":[{"type":"print","value":"0022-2828"}],"subject":[],"published":{"date-parts":[[2010,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Actin in action and inaction: The differential effects of hypertrophic and dilated cardiomyopathy actin mutations on thin filament regulation","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2009.10.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}