{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T19:48:44Z","timestamp":1787255324671,"version":"build-2736575974"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.yjmcc.2013.11.009","type":"journal-article","created":{"date-parts":[[2013,11,20]],"date-time":"2013-11-20T23:16:38Z","timestamp":1384989398000},"page":"133-140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["The time-of-day variation in vascular smooth muscle contractility depends on a nitric oxide signalling pathway"],"prefix":"10.1016","volume":"66","author":[{"given":"M.","family":"Denniff","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen E.","family":"Turrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8156-1608","authenticated-orcid":false,"given":"Andrew","family":"Vanezis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn C.","family":"Rodrigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yjmcc.2013.11.009_bb0005","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1161\/01.HYP.18.2.199","article-title":"Quantitative analysis of the 24-hour blood pressure and heart rate patterns in young men","volume":"18","author":"Degaute","year":"1991","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0010","first-page":"H982","article-title":"Nocturnal variations in peripheral blood flow, systemic blood pressure, and heart rate in humans","volume":"261","author":"Sindrup","year":"1991","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0015","first-page":"R779","article-title":"Diurnal patterns of hemodynamic performance in nonhuman primates","volume":"253","author":"Engel","year":"1987","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0020","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1161\/01.HYP.26.1.55","article-title":"Circadian profile of systemic hemodynamics","volume":"26","author":"Veerman","year":"1995","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0025","first-page":"H1335","article-title":"Hemodynamic monitoring for 24h in unanesthetized rats","volume":"253","author":"Smith","year":"1987","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0030","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.pharmthera.2005.11.008","article-title":"The importance of circadian rhythms on drug response in hypertension and coronary heart disease\u2014from mice and man","volume":"111","author":"Lemmer","year":"2006","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0035","first-page":"S42","article-title":"Dippers versus non-dippers","volume":"9","author":"Verdecchia","year":"1991","journal-title":"J Hypertens Suppl"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0040","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S0895-7061(97)00317-8","article-title":"Leg versus forearm flow: 24h monitoring in 14 normotensive subjects and in 14 age-matched hypertensive patients confined to bed","volume":"11","author":"Casiglia","year":"1998","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0045","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3109\/07420529808998678","article-title":"Effects of SCN lesions on circadian blood pressure rhythm in normotensive and transgenic hypertensive rats","volume":"15","author":"Witte","year":"1998","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0050","first-page":"S125","article-title":"Circadian blood pressure variations under different pathophysiological conditions","volume":"8","author":"Imai","year":"1990","journal-title":"J Hypertens Suppl"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0055","doi-asserted-by":"crossref","first-page":"465","DOI":"10.3109\/07420529609020917","article-title":"Twenty-four-hour variations in the sensitivity of rat aorta to vasoactive agents","volume":"13","author":"Keskil","year":"1996","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0060","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1081\/CBI-100106080","article-title":"Day-night variation in the in vitro contractility of aorta and mesenteric and renal arteries in transgenic hypertensive rats","volume":"18","author":"Witte","year":"2001","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0065","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1161\/01.CIR.103.6.806","article-title":"Diurnal variation in endothelium-dependent vasodilatation is not apparent in coronary artery disease","volume":"103","author":"Shaw","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0070","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1038\/sj.bjp.0701940","article-title":"Nitric oxide (NO)-induced activation of large conductance Ca2+-dependent K+ channels (BK(Ca)) in smooth muscle cells isolated from the rat mesenteric artery","volume":"124","author":"Mistry","year":"1998","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0075","doi-asserted-by":"crossref","first-page":"7583","DOI":"10.1073\/pnas.91.16.7583","article-title":"Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase","volume":"91","author":"Archer","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0080","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1124\/pr.110.002907","article-title":"cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action","volume":"62","author":"Francis","year":"2010","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0085","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/S0008-6363(95)00072-0","article-title":"Contribution of the nitric oxide-guanylyl cyclase system to circadian regulation of blood pressure in normotensive Wistar\u2013Kyoto rats","volume":"30","author":"Witte","year":"1995","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0090","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1177\/074873099129000722","article-title":"Nocturnal increase in plasma cGMP levels in humans","volume":"14","author":"Zhdanova","year":"1999","journal-title":"J Biol Rhythms"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0095","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1124\/jpet.105.095828","article-title":"Further characterization of the time-dependent vascular effects of delta9-tetrahydrocannabinol","volume":"317","author":"O'Sullivan","year":"2006","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0100","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1161\/CIRCRESAHA.109.213942","article-title":"Inotropic response of cardiac ventricular myocytes to beta-adrenergic stimulation with isoproterenol exhibits diurnal variation: involvement of nitric oxide","volume":"106","author":"Collins","year":"2010","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0105","doi-asserted-by":"crossref","first-page":"H621","DOI":"10.1152\/ajpheart.00825.2011","article-title":"Altered clock gene expression and vascular smooth muscle diurnal contractile variations in type 2 diabetic db\/db mice","volume":"302","author":"Su","year":"2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0110","first-page":"H76","article-title":"Nitrovasodilators relax mesenteric microvessels by cGMP-induced stimulation of Ca-activated K channels","volume":"273","author":"Carrier","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0115","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1081\/CBI-120002915","article-title":"Circadian variation of nitric oxide synthase activity in mouse tissue","volume":"19","author":"anaTunctan","year":"2002","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0120","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1097\/00004872-200306000-00010","article-title":"Circadian gene expression of clock genes and plasminogen activator inhibitor-1 in heart and aorta of spontaneously hypertensive and Wistar\u2013Kyoto rats","volume":"21","author":"Naito","year":"2003","journal-title":"J Hypertens"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0125","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/00005344-200308000-00012","article-title":"Involvement of the beta3 adrenoceptor in nebivolol-induced vasorelaxation in the rat aorta","volume":"42","author":"de Groot","year":"2003","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0130","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1161\/CIRCULATIONAHA.104.532960","article-title":"Endothelial beta3-adrenoreceptors mediate nitric oxide-dependent vasorelaxation of coronary microvessels in response to the third-generation beta-blocker nebivolol","volume":"112","author":"Dessy","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0135","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1161\/01.CIR.0000139331.85766.AF","article-title":"Endothelial beta3-adrenoceptors mediate vasorelaxation of human coronary microarteries through nitric oxide and endothelium-dependent hyperpolarization","volume":"110","author":"Dessy","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0140","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s00395-010-0110-7","article-title":"Altered circadian rhythm of cardiac beta3-adrenoceptor activity following myocardial infarction in the rat","volume":"106","author":"Zhou","year":"2011","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0145","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/sj.bjp.0706369","article-title":"Direct demonstration of beta1- and evidence against beta2- and beta3-adrenoceptors, in smooth muscle cells of rat small mesenteric arteries","volume":"146","author":"Briones","year":"2005","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0150","doi-asserted-by":"crossref","first-page":"4527","DOI":"10.1074\/jbc.R000028200","article-title":"Dedicated myosin light chain kinases with diverse cellular functions","volume":"276","author":"Kamm","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0155","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1152\/physrev.00023.2003","article-title":"Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase","volume":"83","author":"Somlyo","year":"2003","journal-title":"Physiol Rev"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1074\/jbc.R400035200","article-title":"The biology of cyclic GMP-dependent protein kinases","volume":"280","author":"Hofmann","year":"2005","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0165","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1161\/CIRCRESAHA.107.165779","article-title":"cGMP-dependent protein kinase I and smooth muscle relaxation: a tale of two isoforms","volume":"101","author":"Surks","year":"2007","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0170","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1042\/bj2520269","article-title":"Cyclic GMP-dependent protein kinase phosphorylates phospholamban in isolated sarcoplasmic reticulum from cardiac and smooth muscle","volume":"252","author":"Raeymaekers","year":"1988","journal-title":"Biochem J"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0175","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/35004606","article-title":"Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta","volume":"404","author":"Schlossmann","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0180","doi-asserted-by":"crossref","first-page":"G1006","DOI":"10.1152\/ajpgi.00465.2002","article-title":"Inhibition of sustained smooth muscle contraction by PKA and PKG preferentially mediated by phosphorylation of RhoA","volume":"284","author":"Murthy","year":"2003","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0185","first-page":"H2173","article-title":"Role of nitric oxide in vasodilator response induced by salbutamol in rat diaphragmatic microcirculation","volume":"272","author":"Chang","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0190","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/sj.bjp.0702797","article-title":"Beta 3-adrenoceptor stimulation induces vasorelaxation mediated essentially by endothelium-derived nitric oxide in rat thoracic aorta","volume":"128","author":"Trochu","year":"1999","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0195","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.pharmthera.2005.12.002","article-title":"beta3-adrenoceptors in the cardiovascular system: putative roles in human pathologies","volume":"111","author":"Rozec","year":"2006","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0200","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1080\/07420520802257695","article-title":"Effect of NO synthase inhibition on cardiovascular circadian rhythms in wild-type and eNOS-knock-out mice","volume":"25","author":"Lemmer","year":"2008","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0205","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1080\/07420520701795357","article-title":"Endothelial nitric oxide is not involved in circadian rhythm generation of blood pressure: experiments in wild-type C57 and eNOS knock-out mice under light-dark and free-run conditions","volume":"24","author":"Arraj","year":"2007","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0210","doi-asserted-by":"crossref","first-page":"e55","DOI":"10.1161\/01.RES.0000047529.26278.4D","article-title":"Nonendothelial source of nitric oxide in arterioles but not in venules: alternative source revealed in vivo by diaminofluorescein microfluorography","volume":"91","author":"Kashiwagi","year":"2002","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.11.009_bb0215","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1161\/CIRCRESAHA.109.209957","article-title":"The cardiomyocyte circadian clock: emerging roles in health and disease","volume":"106","author":"Durgan","year":"2010","journal-title":"Circ Res"}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282813003416?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282813003416?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T05:58:29Z","timestamp":1762667909000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282813003416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":43,"alternative-id":["S0022282813003416"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2013.11.009","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The time-of-day variation in vascular smooth muscle contractility depends on a nitric oxide signalling pathway","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2013.11.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}