{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:12:40Z","timestamp":1790233960168,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1016\/j.yjmcc.2013.12.004","type":"journal-article","created":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T02:00:17Z","timestamp":1387159217000},"page":"60-68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"special_numbering":"C","title":["The signaling pathway for aldosterone-induced mitochondrial production of superoxide anion in the myocardium"],"prefix":"10.1016","volume":"67","author":[{"given":"M.B.","family":"Nolly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.I.","family":"Caldiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Yeves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.C.","family":"Villa-Abrille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.E.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Amado Mondaca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique L.","family":"Portiansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.E.","family":"Chiappe de Cingolani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.E.","family":"Cingolani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.L.","family":"Ennis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yjmcc.2013.12.004_bb0005","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators","volume":"341","author":"Pitt","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0010","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1056\/NEJMoa030207","article-title":"Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction","volume":"348","author":"Pitt","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0015","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1009492","article-title":"Eplerenone in patients with systolic heart failure and mild symptoms","volume":"364","author":"Zannad","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0020","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s10557-010-6256-6","article-title":"Aldosterone inhibition and cardiovascular protection: more important than it once appeared","volume":"24","author":"Martinez","year":"2010","journal-title":"Cardiovasc Drugs Ther"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0025","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.mce.2009.02.005","article-title":"New aspects of rapid aldosterone signaling","volume":"308","author":"Grossmann","year":"2009","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0030","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1172\/JCI200524408","article-title":"Oxygen, oxidative stress, hypoxia, and heart failure","volume":"115","author":"Giordano","year":"2005","journal-title":"J Clin Invest"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0035","doi-asserted-by":"crossref","first-page":"28938","DOI":"10.1074\/jbc.M110.154948","article-title":"Impaired S-nitrosylation of the ryanodine receptor caused by xanthine oxidase activity contributes to calcium leak in heart failure","volume":"285","author":"Gonzalez","year":"2010","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0040","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.cardfail.2006.05.005","article-title":"The effect of xanthine oxidase inhibition upon ejection fraction in heart failure patients: La Plata Study","volume":"12","author":"Cingolani","year":"2006","journal-title":"J Card Fail"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0045","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1751-7133.2011.00200.x","article-title":"Uric acid as a predictor of all-cause mortality in heart failure: a meta-analysis","volume":"17","author":"Tamariz","year":"2011","journal-title":"Congest Heart Fail"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0050","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1161\/01.HYP.0000176236.55322.18","article-title":"Aldosterone stimulates matrix metalloproteinases and reactive oxygen species in adult rat ventricular cardiomyocytes","volume":"46","author":"Rude","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0055","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1291\/hypres.31.363","article-title":"Aldosterone nongenomically produces NADPH oxidase-dependent reactive oxygen species and induces myocyte apoptosis","volume":"31","author":"Hayashi","year":"2008","journal-title":"Hypertens Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0060","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1161\/CIRCULATIONAHA.110.983023","article-title":"Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction","volume":"123","author":"Fraccarollo","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0065","doi-asserted-by":"crossref","first-page":"F529","DOI":"10.1152\/ajprenal.00596.2010","article-title":"Aldosterone stimulates superoxide production in macula densa cells","volume":"301","author":"Zhu","year":"2011","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0070","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1152\/japplphysiol.01344.2010","article-title":"Silencing of NHE-1 blunts the slow force response to myocardial stretch","volume":"111","author":"Perez","year":"2011","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0075","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1038\/sj.gt.3302768","article-title":"AAV delivery of mineralocorticoid receptor shRNA prevents progression of cold-induced hypertension and attenuates renal damage","volume":"13","author":"Wang","year":"2006","journal-title":"Gene Ther"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0080","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1113\/jphysiol.2007.141689","article-title":"Mitochondrial reactive oxygen species activate the slow force response to stretch in feline myocardium","volume":"584","author":"Caldiz","year":"2007","journal-title":"J Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0085","first-page":"H1528","article-title":"Angiotensin II stimulates cardiac L-type Ca(2+) current by a Ca(2+)- and protein kinase C-dependent mechanism","volume":"280","author":"Aiello","year":"2001","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0090","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1074\/jbc.273.4.2015","article-title":"Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems","volume":"273","author":"Li","year":"1998","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0095","first-page":"H2039","article-title":"Cardiac oxidative stress is involved in heart failure induced by thiamine deprivation in rats","volume":"298","author":"Gioda","year":"2010","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0100","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1038\/sj.bjp.0706220","article-title":"Genomic and nongenomic effects of aldosterone in the rat heart: why is spironolactone cardioprotective?","volume":"145","author":"Chai","year":"2005","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0105","doi-asserted-by":"crossref","first-page":"7665","DOI":"10.1074\/jbc.M809460200","article-title":"Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells","volume":"284","author":"Maron","year":"2009","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0110","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1161\/HYPERTENSIONAHA.110.161653","article-title":"GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone","volume":"57","author":"Gros","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0115","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1161\/HYPERTENSIONAHA.109.136242","article-title":"Glucocorticoids activate cardiac mineralocorticoid receptors during experimental myocardial infarction","volume":"54","author":"Mihailidou","year":"2009","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0120","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1161\/CIRCRESAHA.106.144956","article-title":"Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: novel basis for modulation of cardiac conduction by gene therapy","volume":"100","author":"Kizana","year":"2007","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0125","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1161\/01.HYP.0000163462.98381.7f","article-title":"Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II","volume":"45","author":"Kimura","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0130","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/S0008-6363(98)00064-9","article-title":"Cyclosporine A limits myocardial infarct size even when administered after onset of ischemia","volume":"38","author":"Weinbrenner","year":"1998","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0135","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1161\/01.HYP.0000165019.32059.b2","article-title":"Triggering mitochondrial radical release: a new function for NADPH oxidases","volume":"45","author":"Brandes","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0140","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1084\/jem.192.7.1001","article-title":"Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the MPT in cardiac myocytes","volume":"192","author":"Zorov","year":"2000","journal-title":"J Exp Med"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0145","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00109-008-0323-5","article-title":"New insights on signaling cascades induced by cross-talk between angiotensin II and aldosterone","volume":"86","author":"Lemarie","year":"2008","journal-title":"J Mol Med"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0150","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1161\/ATVBAHA.108.168021","article-title":"Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways","volume":"28","author":"Montezano","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0155","doi-asserted-by":"crossref","first-page":"F1323","DOI":"10.1152\/ajprenal.90428.2008","article-title":"Aldosterone-induced mesangial cell proliferation is mediated by EGF receptor transactivation","volume":"296","author":"Huang","year":"2009","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0160","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1161\/HYPERTENSIONAHA.111.176024","article-title":"Aldosterone stimulates the cardiac Na(+)\/H(+) exchanger via transactivation of the epidermal growth factor receptor","volume":"58","author":"De Giusti","year":"2011","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0165","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1161\/01.RES.0000033523.08033.16","article-title":"Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators","volume":"91","author":"Seshiah","year":"2002","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0170","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.yjmcc.2003.12.013","article-title":"Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF","volume":"36","author":"Krieg","year":"2004","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0175","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1161\/CIRCRESAHA.107.162800","article-title":"Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction","volume":"102","author":"Doughan","year":"2008","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0180","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1196\/annals.1420.022","article-title":"Mapping preconditioning's signaling pathways: an engineering approach","volume":"1123","author":"Downey","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0185","first-page":"H406","article-title":"The direct physiological effects of mitoK(ATP) opening on heart mitochondria","volume":"290","author":"Costa","year":"2006","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0190","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1152\/japplphysiol.90616.2008","article-title":"Na+\/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action","volume":"105","author":"Garciarena","year":"2008","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0195","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.cell.2008.06.017","article-title":"Superoxide flashes in single mitochondria","volume":"134","author":"Wang","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0200","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1161\/hy02t2.102909","article-title":"Increased angiotensin II-mediated Src signaling via epidermal growth factor receptor transactivation is associated with decreased C-terminal Src kinase activity in vascular smooth muscle cells from spontaneously hypertensive rats","volume":"39","author":"Touyz","year":"2002","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0205","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1113\/jphysiol.2009.186619","article-title":"The Anrep effect requires transactivation of the epidermal growth factor receptor","volume":"588","author":"Villa-Abrille","year":"2010","journal-title":"J Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0210","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1124\/jpet.113.206243","volume":"347","author":"Ulu","year":"2013","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0215","doi-asserted-by":"crossref","first-page":"C1","DOI":"10.1152\/ajpcell.00620.2005","article-title":"ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors","volume":"291","author":"Ohtsu","year":"2006","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0220","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1161\/01.HYP.0000258594.87211.6b","article-title":"Measurement of reactive oxygen species in cardiovascular studies","volume":"49","author":"Dikalov","year":"2007","journal-title":"Hypertension"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0225","doi-asserted-by":"crossref","first-page":"5130","DOI":"10.1073\/pnas.1031526100","article-title":"Modulation of p47PHOX activity by site-specific phosphorylation: Akt-dependent activation of the NADPH oxidase","volume":"100","author":"Hoyal","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0230","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.yjmcc.2010.12.018","article-title":"Regulation of myocardial growth and death by NADPH oxidase","volume":"50","author":"Maejima","year":"2011","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0235","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1161\/CIRCRESAHA.109.213116","article-title":"Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes","volume":"106","author":"Ago","year":"2010","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0240","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1089\/ars.2008.2363","article-title":"Signaling components of redox active endosomes: the redoxosomes","volume":"11","author":"Oakley","year":"2009","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0245","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1161\/hh2401.101752","article-title":"Characteristics and superoxide-induced activation of reconstituted myocardial mitochondrial ATP-sensitive potassium channels","volume":"89","author":"Zhang","year":"2001","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0250","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0008-6363(02)00861-1","article-title":"Activation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals","volume":"58","author":"Krieg","year":"2003","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0255","first-page":"H2322","article-title":"ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases","volume":"283","author":"Krieg","year":"2002","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0260","first-page":"H2606","article-title":"Acetylcholine and bradykinin trigger preconditioning in the heart through a pathway that includes Akt and NOS","volume":"287","author":"Krieg","year":"2004","journal-title":"Am J Physiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0265","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1038\/bjp.2008.189","article-title":"Chronic inhibition of the Na+\/H+-exchanger causes regression of hypertrophy, heart failure, and ionic and electrophysiological remodelling","volume":"154","author":"Baartscheer","year":"2008","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0270","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1161\/01.RES.0000014966.97486.C0","article-title":"Inhibition of Na(+)\u2013H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice","volume":"90","author":"Engelhardt","year":"2002","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0275","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1161\/CIRCRESAHA.108.175141","article-title":"Activation of Na+\/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure","volume":"103","author":"Nakamura","year":"2008","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0280","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.yjmcc.2008.10.013","article-title":"Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress?","volume":"46","author":"Cook","year":"2009","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0285","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1159\/000325201","article-title":"Myocardial reperfusion injury: reactive oxygen species vs. NHE-1 reactivation","volume":"27","author":"Garciarena","year":"2011","journal-title":"Cell Physiol Biochem"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0290","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1161\/01.RES.82.10.1053","article-title":"Hydrogen peroxide activates mitogen-activated protein kinases and Na+\u2013H+ exchange in neonatal rat cardiac myocytes","volume":"82","author":"Sabri","year":"1998","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2013.12.004_bb0295","first-page":"H1125","article-title":"Transient opening of mitochondrial permeability transition pore by reactive oxygen species protects myocardium from ischemia-reperfusion injury","volume":"296","author":"Saotome","year":"2009","journal-title":"Am J Physiol"}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282813003532?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282813003532?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,4]],"date-time":"2019-08-04T19:29:08Z","timestamp":1564946948000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282813003532"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":59,"alternative-id":["S0022282813003532"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2013.12.004","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The signaling pathway for aldosterone-induced mitochondrial production of superoxide anion in the myocardium","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2013.12.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}