{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T16:32:00Z","timestamp":1785774720999,"version":"3.56.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["jmmc-online.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1016\/j.yjmcc.2014.09.029","type":"journal-article","created":{"date-parts":[[2014,10,6]],"date-time":"2014-10-06T06:02:55Z","timestamp":1412575375000},"page":"73-79","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":54,"special_numbering":"C","title":["The role of autophagic degradation in the heart"],"prefix":"10.1016","volume":"78","author":[{"given":"Kazuhiko","family":"Nishida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Taneike","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kinya","family":"Otsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yjmcc.2014.09.029_bb0005","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1038\/nrm3696","article-title":"The autophagosome: origins unknown, biogenesis complex","volume":"14","author":"Lamb","year":"2013","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0010","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1146\/annurev-cellbio-092910-154005","article-title":"The role of Atg proteins in autophagosome formation","volume":"27","author":"Mizushima","year":"2011","journal-title":"Annu Rev Cell Dev Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0015","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.cell.2011.10.026","article-title":"Autophagy: renovation of cells and tissues","volume":"147","author":"Mizushima","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0020","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1038\/nature03029","article-title":"The role of autophagy during the early neonatal starvation period","volume":"432","author":"Kuma","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0025","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1083\/jcb.200412022","article-title":"Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice","volume":"169","author":"Komatsu","year":"2005","journal-title":"J Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0030","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.exger.2014.01.021","article-title":"Mitochondrial homeostasis: the interplay between mitophagy and mitochondrial biogenesis","volume":"56","author":"Palikaras","year":"2014","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0035","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrm3028","article-title":"Mechanisms of mitophagy","volume":"12","author":"Youle","year":"2011","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0040","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/sj.emboj.7601963","article-title":"Fission and selective fusion govern mitochondrial segregation and elimination by autophagy","volume":"27","author":"Twig","year":"2008","journal-title":"EMBO J"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0045","first-page":"451","article-title":"Mitochondrial dismissal in mammals, from protein degradation to mitophagy","volume":"2014","author":"Campello","year":"1837","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0050","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/ncb2220","article-title":"During autophagy mitochondria elongate, are spared from degradation and sustain cell viability","volume":"13","author":"Gomes","year":"2011","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0055","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/nature11910","article-title":"Autophagosomes form at ER-mitochondria contact sites","volume":"495","author":"Hamasaki","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0060","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1083\/jcb.200803137","article-title":"Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum","volume":"182","author":"Axe","year":"2008","journal-title":"J Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0065","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1083\/jcb.201202061","article-title":"Atg9 vesicles are an important membrane source during early steps of autophagosome formation","volume":"198","author":"Yamamoto","year":"2012","journal-title":"J Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0070","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.tibs.2013.12.001","article-title":"At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy","volume":"39","author":"Shen","year":"2014","journal-title":"Trends Biochem Sci"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0075","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1126\/science.1174447","article-title":"A gene network regulating lysosomal biogenesis and function","volume":"325","author":"Sardiello","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0080","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.cell.2012.11.001","article-title":"The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes\/lysosomes","volume":"151","author":"Itakura","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0085","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.febslet.2010.01.018","article-title":"Atg8-family interacting motif crucial for selective autophagy","volume":"584","author":"Noda","year":"2010","journal-title":"FEBS Lett"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0090","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.devcel.2009.06.013","article-title":"Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy","volume":"17","author":"Okamoto","year":"2009","journal-title":"Dev Cell"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0095","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.devcel.2009.06.014","article-title":"Atg32 is a mitochondrial protein that confers selectivity during mitophagy","volume":"17","author":"Kanki","year":"2009","journal-title":"Dev Cell"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0100","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/cdd.2009.16","article-title":"Role of BNIP3 and NIX in cell death, autophagy, and mitophagy","volume":"16","author":"Zhang","year":"2009","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0105","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/embor.2009.256","article-title":"Nix is a selective autophagy receptor for mitochondrial clearance","volume":"11","author":"Novak","year":"2010","journal-title":"EMBO Rep"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0110","doi-asserted-by":"crossref","first-page":"19094","DOI":"10.1074\/jbc.M111.322933","article-title":"Microtubule-associated protein 1 light chain 3 (LC3) interacts with Bnip3 protein to selectively remove endoplasmic reticulum and mitochondria via autophagy","volume":"287","author":"Hanna","year":"2012","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0115","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/ncb2422","article-title":"Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells","volume":"14","author":"Liu","year":"2012","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0120","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/33416","article-title":"Mutations in the Parkin gene cause autosomal recessive juvenile parkinsonism","volume":"392","author":"Kitada","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0125","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1126\/science.1096284","article-title":"Hereditary early-onset Parkinson's disease caused by mutations in PINK1","volume":"304","author":"Valente","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0130","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1038\/ncb2012","article-title":"PINK1\/Parkin-mediated mitophagy is dependent on VDAC1 and p62\/SQSTM1","volume":"12","author":"Geisler","year":"2010","journal-title":"Nat Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0135","doi-asserted-by":"crossref","first-page":"4861","DOI":"10.1093\/hmg\/ddq419","article-title":"Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1\/Parkin-dependent manner upon induction of mitophagy","volume":"19","author":"Gegg","year":"2010","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0140","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1161\/CIRCRESAHA.112.265819","article-title":"Mitochondria and mitophagy: the yin and yang of cell death control","volume":"111","author":"Kubli","year":"2012","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0145","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1083\/jcb.201001039","article-title":"Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy","volume":"189","author":"Lee","year":"2010","journal-title":"J Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0150","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.4161\/auto.6.8.13426","article-title":"p62\/SQSTM1 is required for parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both","volume":"6","author":"Narendra","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0155","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/j.molcel.2009.01.020","article-title":"A role for NBR1 in autophagosomal degradation of ubiquitinated substrates","volume":"33","author":"Kirkin","year":"2009","journal-title":"Mol Cell"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0160","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.molcel.2014.06.001","article-title":"Bcl-2 family proteins participate in mitochondrial quality control by regulating parkin\/PINK1-dependent mitophagy","volume":"55","author":"Hollville","year":"2014","journal-title":"Mol Cell"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0165","doi-asserted-by":"crossref","first-page":"10249","DOI":"10.1523\/JNEUROSCI.1917-11.2011","article-title":"Parkin interacts with Ambra1 to induce mitophagy","volume":"31","author":"Van Humbeeck","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0170","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0165-3806(01)00234-6","article-title":"Differential expression and tissue distribution of parkin isoforms during mouse development","volume":"130","author":"Huynh","year":"2001","journal-title":"Dev Brain Res"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0175","doi-asserted-by":"crossref","first-page":"48120","DOI":"10.1074\/jbc.M306889200","article-title":"Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age","volume":"278","author":"Pawlyk","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0180","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1083\/jcb.200910140","article-title":"PINK1 stabilized by mitochondrial depolarization recruits parkin to damaged mitochondria and activates latent parkin for mitophagy","volume":"189","author":"Matsuda","year":"2010","journal-title":"J Cell Biol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0185","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1161\/01.RES.56.3.377","article-title":"Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, and from human hearts","volume":"56","author":"Schaper","year":"1985","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0190","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/nm1574","article-title":"The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress","volume":"13","author":"Nakai","year":"2007","journal-title":"Nat Med"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0195","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/nature08455","article-title":"Discovery of Atg5\/Atg7-independent alternative macroautophagy","volume":"461","author":"Nishida","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0200","doi-asserted-by":"crossref","first-page":"4004","DOI":"10.1038\/ncomms5004","article-title":"Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes","volume":"5","author":"Honda","year":"2014","journal-title":"Nat Commun"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0205","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1007\/s10741-012-9346-7","article-title":"Alterations in mitochondrial function in cardiac hypertrophy and heart failure","volume":"18","author":"Osterholt","year":"2013","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0210","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1056\/NEJM199005313222203","article-title":"Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study","volume":"322","author":"Levy","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0215","doi-asserted-by":"crossref","first-page":"4123","DOI":"10.1073\/pnas.1015081108","article-title":"Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy","volume":"108","author":"Cao","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0220","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/j.bbrc.2013.10.135","article-title":"Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading","volume":"441","author":"Oyabu","year":"2013","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0225","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1146\/annurev.me.36.020185.002203","article-title":"Reversal of cardiac hypertrophy by medical treatment","volume":"36","author":"Tarazi","year":"1985","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0230","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/0003-4975(96)00533-4","article-title":"Left ventricular mass regression early after aortic valve replacement","volume":"62","author":"Christakis","year":"1996","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0235","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1161\/01.CIR.98.7.656","article-title":"Regression of cellular hypertrophy after left ventricular assist device support","volume":"98","author":"Zafeiridis","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0240","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1001\/jama.1996.03530430051039","article-title":"Reversal of left ventricular hypertrophy in essential hypertension. A meta-analysis of randomized double-blind studies","volume":"275","author":"Schmieder","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0245","doi-asserted-by":"crossref","first-page":"e51632","DOI":"10.1371\/journal.pone.0051632","article-title":"Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heart","volume":"8","author":"Hariharan","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0250","doi-asserted-by":"crossref","first-page":"e000016","DOI":"10.1161\/JAHA.113.000016","article-title":"Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy","volume":"2","author":"Cao","year":"2013","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0255","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.cardiores.2003.11.014","article-title":"Metabolic remodelling of the failing heart: the cardiac burn-out syndrome?","volume":"61","author":"Vanbilsen","year":"2004","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0260","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/cdd.2008.163","article-title":"The role of autophagy in the heart","volume":"16","author":"Nishida","year":"2009","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0265","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nature10992","article-title":"Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure","volume":"485","author":"Oka","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0270","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1172\/JCI27523","article-title":"Cardiac autophagy is a maladaptive response to hemodynamic stress","volume":"117","author":"Zhu","year":"2007","journal-title":"J Clin Invest"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0275","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1161\/CIRCRESAHA.108.186551","article-title":"Autophagy in load-induced heart disease","volume":"103","author":"Rothermel","year":"2008","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0280","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1212\/WNL.31.1.51","article-title":"Lysosomal glycogen storage disease with normal acid maltase","volume":"31","author":"Danon","year":"1981","journal-title":"Neurology"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0285","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/jhg.2012.72","article-title":"Danon disease: focusing on heart","volume":"57","author":"Cheng","year":"2012","journal-title":"J Hum Genet"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0290","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1038\/35022595","article-title":"Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice","volume":"406","author":"Tanaka","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0295","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1038\/35022604","article-title":"Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease)","volume":"406","author":"Nishino","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0300","doi-asserted-by":"crossref","first-page":"9745","DOI":"10.1073\/pnas.0706802105","article-title":"Autophagy is an adaptive response in desmin-related cardiomyopathy","volume":"105","author":"Tannous","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0305","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1161\/CIRCRESAHA.110.237339","article-title":"Atg7 induces basal autophagy and rescues autophagic deficiency in CryABR120G cardiomyocytes","volume":"109","author":"Pattison","year":"2011","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0310","doi-asserted-by":"crossref","first-page":"5284","DOI":"10.1172\/JCI70877","article-title":"Enhanced autophagy ameliorates cardiac proteinopathy","volume":"123","author":"Bhuiyan","year":"2013","journal-title":"J Clin Invest"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0315","article-title":"Autophagy and mitophagy in diabetic cardiomyopathy","author":"Kobayashi","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0320","doi-asserted-by":"crossref","first-page":"18077","DOI":"10.1074\/jbc.M113.474650","article-title":"Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes","volume":"288","author":"Xu","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0325","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1161\/CIRCRESAHA.111.246108","article-title":"Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities","volume":"110","author":"Dutta","year":"2012","journal-title":"Circ Res"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0330","doi-asserted-by":"crossref","first-page":"600","DOI":"10.4161\/auto.6.5.11947","article-title":"Inhibition of autophagy in the heart induces age-related cardiomyopathy","volume":"6","author":"Taneike","year":"2010","journal-title":"Autophagy"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0335","doi-asserted-by":"crossref","first-page":"2300","DOI":"10.1038\/ncomms3300","article-title":"Overexpression of Atg5 in mice activates autophagy and extends lifespan","volume":"4","author":"Pyo","year":"2013","journal-title":"Nat Commun"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0340","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.yjmcc.2014.07.013","article-title":"Mitochondrial quality control in the myocardium: cooperation between protein degradation and mitophagy","volume":"75","author":"Hammerling","year":"2014","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0345","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1038\/ncomms3308","article-title":"Cytosolic p53 inhibits parkin-mediated mitophagy and promotes mitochondrial dysfunction in the mouse heart","volume":"4","author":"Hoshino","year":"2013","journal-title":"Nat Commun"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0350","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1074\/jbc.M112.411363","article-title":"Parkin protein deficiency exacerbates cardiac injury and reduces survival following myocardial infarction","volume":"288","author":"Kubli","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.yjmcc.2014.09.029_bb0355","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1471-4159.2007.04762.x","article-title":"Mortality, oxidative stress and tau accumulation during ageing in parkin null mice","volume":"103","author":"Rodriguez-Navarro","year":"2007","journal-title":"J Neurochem"}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282814003101?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282814003101?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T13:35:36Z","timestamp":1717421736000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282814003101"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":71,"alternative-id":["S0022282814003101"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2014.09.029","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of autophagic degradation in the heart","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2014.09.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}