{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:06:15Z","timestamp":1792757175669,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["CIHR-MOP-133547"],"award-info":[{"award-number":["CIHR-MOP-133547"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.yjmcc.2019.04.008","type":"journal-article","created":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T12:31:34Z","timestamp":1555504294000},"page":"29-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Heparanase protects the heart against chemical or ischemia\/reperfusion injury"],"prefix":"10.1016","volume":"131","author":[{"given":"Fulong","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Pulinilkunnil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane","family":"Flibotte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey","family":"Nislow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israel","family":"Vlodavsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahira","family":"Hussein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.yjmcc.2019.04.008_bb0005","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a004952","article-title":"Heparan sulfate proteoglycans","volume":"3","author":"Sarrazin","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"35","key":"10.1016\/j.yjmcc.2019.04.008_bb0010","doi-asserted-by":"crossref","first-page":"30377","DOI":"10.1074\/jbc.M111.254789","article-title":"Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype","volume":"286","author":"Purushothaman","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.yjmcc.2019.04.008_bb0015","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.tibs.2017.10.007","article-title":"Opposing functions of heparanase-1 and heparanase-2 in cancer progression","volume":"43","author":"Vlodavsky","year":"2018","journal-title":"Trends Biochem. Sci."},{"issue":"4","key":"10.1016\/j.yjmcc.2019.04.008_bb0020","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrneph.2017.6","article-title":"Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease","volume":"13","author":"Rabelink","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0025","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1096\/fj.04-1970com","article-title":"Heparanase accelerates wound angiogenesis and wound healing in mouse and rat models","volume":"19","author":"Zcharia","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0030","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.drup.2016.10.001","article-title":"Heparanase: from basic research to therapeutic applications in cancer and inflammation","volume":"29","author":"Vlodavsky","year":"2016","journal-title":"Drug Resist. Updat."},{"issue":"8","key":"10.1016\/j.yjmcc.2019.04.008_bb0035","doi-asserted-by":"crossref","first-page":"5053","DOI":"10.1074\/jbc.M114.600569","article-title":"Overexpression of heparanase lowers the amyloid burden in amyloid-beta precursor protein transgenic mice","volume":"290","author":"Jendresen","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"18","key":"10.1016\/j.yjmcc.2019.04.008_bb0040","doi-asserted-by":"crossref","first-page":"6473","DOI":"10.1073\/pnas.0502287102","article-title":"In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein a amyloidosis","volume":"102","author":"Li","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.yjmcc.2019.04.008_bb0045","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2337\/db16-0761","article-title":"Heparanase overexpression induces glucagon resistance and protects animals from chemically induced diabetes","volume":"66","author":"Zhang","year":"2017","journal-title":"Diabetes"},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0050","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1093\/cvr\/cvw211","article-title":"High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature","volume":"112","author":"Wang","year":"2016","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0055","first-page":"193","article-title":"ER protein quality control and the unfolded protein response in the heart","volume":"414","author":"Arrieta","year":"2018","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0060","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.yjmcc.2018.02.013","article-title":"The unfolded protein response in ischemic heart disease","volume":"117","author":"Wang","year":"2018","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"10","key":"10.1016\/j.yjmcc.2019.04.008_bb0065","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1161\/CIRCRESAHA.110.227033","article-title":"Biology of endoplasmic reticulum stress in the heart","volume":"107","author":"Groenendyk","year":"2010","journal-title":"Circ. Res."},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0070","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.tibs.2015.01.002","article-title":"UPR, autophagy, and mitochondria crosstalk underlies the ER stress response","volume":"40","author":"Senft","year":"2015","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0075","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3389\/fcvm.2017.00029","article-title":"Role of endoplasmic reticulum stress, autophagy, and inflammation in cardiovascular disease","volume":"4","author":"Zhang","year":"2017","journal-title":"Front. Cardiovasc. Med."},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0080","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1161\/CIRCRESAHA.108.187427","article-title":"Autophagy in ischemic heart disease","volume":"104","author":"Gustafsson","year":"2009","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0085","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.bbadis.2014.05.010","article-title":"The role of the autophagy in myocardial ischemia\/reperfusion injury","volume":"1852","author":"Ma","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"issue":"6","key":"10.1016\/j.yjmcc.2019.04.008_bb0090","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1161\/01.RES.0000261924.76669.36","article-title":"Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy","volume":"100","author":"Matsui","year":"2007","journal-title":"Circ. Res."},{"issue":"18","key":"10.1016\/j.yjmcc.2019.04.008_bb0095","doi-asserted-by":"crossref","first-page":"3946","DOI":"10.1158\/0008-5472.CAN-15-0037","article-title":"Heparanase enhances tumor growth and chemoresistance by promoting autophagy","volume":"75","author":"Shteingauz","year":"2015","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0100","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/S0008-6363(96)00201-5","article-title":"Cardiac lipoprotein lipase in the spontaneously hypertensive rat","volume":"33","author":"Sambandam","year":"1997","journal-title":"Cardiovasc. Res."},{"issue":"114","key":"10.1016\/j.yjmcc.2019.04.008_bb0105","doi-asserted-by":"crossref","DOI":"10.3791\/54012","article-title":"Isolation, culture and transduction of adult mouse cardiomyocytes","author":"Judd","year":"2016","journal-title":"J. Vis. Exp."},{"issue":"99","key":"10.1016\/j.yjmcc.2019.04.008_bb0110","doi-asserted-by":"crossref","DOI":"10.3791\/52197","article-title":"Minimal invasive surgical procedure of inducing myocardial infarction in mice","author":"Curaj","year":"2015","journal-title":"J. Vis. Exp."},{"issue":"12","key":"10.1016\/j.yjmcc.2019.04.008_bb0115","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"issue":"16","key":"10.1016\/j.yjmcc.2019.04.008_bb0120","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1093\/bioinformatics\/bts356","article-title":"RSeQC: quality control of RNA-seq experiments","volume":"28","author":"Wang","year":"2012","journal-title":"Bioinformatics"},{"issue":"7","key":"10.1016\/j.yjmcc.2019.04.008_bb0125","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/nbt.1883","article-title":"Full-length transcriptome assembly from RNA-Seq data without a reference genome","volume":"29","author":"Grabherr","year":"2011","journal-title":"Nat. Biotechnol."},{"issue":"5","key":"10.1016\/j.yjmcc.2019.04.008_bb0130","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.molmet.2017.02.005","article-title":"Loss of hepatic DEPTOR alters the metabolic transition to fasting","volume":"6","author":"Caron","year":"2017","journal-title":"Mol. Metab."},{"issue":"22","key":"10.1016\/j.yjmcc.2019.04.008_bb0135","first-page":"7733","article-title":"Heparanase affects adhesive and tumorigenic potential of human glioma cells","volume":"63","author":"Zetser","year":"2003","journal-title":"Cancer Res."},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0140","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nrm3270","article-title":"The unfolded protein response: controlling cell fate decisions under ER stress and beyond","volume":"13","author":"Hetz","year":"2012","journal-title":"Nat. Rev. Mol. Cell. Bio."},{"issue":"5","key":"10.1016\/j.yjmcc.2019.04.008_bb0145","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1161\/CIRCRESAHA.116.310266","article-title":"ATF6 decreases myocardial ischemia\/reperfusion damage and links ER stress and oxidative stress Signaling pathways in the heart","volume":"120","author":"Jin","year":"2017","journal-title":"Circ. Res."},{"issue":"11","key":"10.1016\/j.yjmcc.2019.04.008_bb0150","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1089\/ars.2010.3486","article-title":"Cardioprotection by endoplasmic reticulum stress-induced autophagy","volume":"14","author":"Petrovski","year":"2011","journal-title":"Antioxid. Redox Signal."},{"issue":"9","key":"10.1016\/j.yjmcc.2019.04.008_bb0155","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1038\/sj.embor.7400779","article-title":"Mediators of endoplasmic reticulum stress-induced apoptosis","volume":"7","author":"Szegezdi","year":"2006","journal-title":"EMBO Rep."},{"issue":"5","key":"10.1016\/j.yjmcc.2019.04.008_bb0160","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/aps.2013.18","article-title":"The protective roles of autophagy in ischemic preconditioning","volume":"34","author":"Yan","year":"2013","journal-title":"Acta Pharmacol. Sin."},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0165","doi-asserted-by":"crossref","first-page":"310","DOI":"10.4161\/auto.18673","article-title":"Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning","volume":"8","author":"Sheng","year":"2012","journal-title":"Autophagy"},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0170","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.amjcard.2010.03.032","article-title":"Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy","volume":"106","author":"Turer","year":"2010","journal-title":"Am. J. Cardiol."},{"issue":"7","key":"10.1016\/j.yjmcc.2019.04.008_bb0175","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/nrcardio.2017.35","article-title":"Myocardial stress and autophagy: mechanisms and potential therapies","volume":"14","author":"Delbridge","year":"2017","journal-title":"Nat. Rev. Cardiol."},{"issue":"7","key":"10.1016\/j.yjmcc.2019.04.008_bb0180","first-page":"850","article-title":"Autophagy, metabolic disease, and pathogenesis of heart dysfunction","volume":"33","author":"Wang","year":"2017","journal-title":"Can. J. Cardiol."},{"issue":"5","key":"10.1016\/j.yjmcc.2019.04.008_bb0185","doi-asserted-by":"crossref","first-page":"3009","DOI":"10.1074\/jbc.M114.592261","article-title":"Calcium-independent phospholipase A2gamma enhances activation of the ATF6 transcription factor during endoplasmic reticulum stress","volume":"290","author":"Elimam","year":"2015","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0190","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1177\/0271678X16650218","article-title":"Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome","volume":"37","author":"Yu","year":"2017","journal-title":"J. Cereb. Blood Flow Metab."},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0195","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1172\/JCI82670","article-title":"Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease","volume":"126","author":"Naranjo","year":"2016","journal-title":"J. Clin. Invest."},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0200","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/jnc.12981","article-title":"Deletion of Atf6alpha impairs astroglial activation and enhances neuronal death following brain ischemia in mice","volume":"132","author":"Yoshikawa","year":"2015","journal-title":"J. Neurochem."},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0205","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.neuint.2015.12.009","article-title":"Deletion of Atf6alpha enhances kainate-induced neuronal death in mice","volume":"92","author":"Kezuka","year":"2016","journal-title":"Neurochem. Int."},{"issue":"8","key":"10.1016\/j.yjmcc.2019.04.008_bb0210","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1016\/j.metabol.2012.01.004","article-title":"Atf6alpha-null mice are glucose intolerant due to pancreatic beta-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance","volume":"61","author":"Usui","year":"2012","journal-title":"Metabolism"},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0215","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1002\/hep.24396","article-title":"Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish","volume":"54","author":"Cinaroglu","year":"2011","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.yjmcc.2019.04.008_bb0220","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.cell.2012.03.050","article-title":"A thrombospondin-dependent pathway for a protective ER stress response","volume":"149","author":"Lynch","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0225","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1038\/s41421-017-0003-0","article-title":"ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells","volume":"4","author":"Wang","year":"2018","journal-title":"Cell Discov."},{"issue":"5","key":"10.1016\/j.yjmcc.2019.04.008_bb0230","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1016\/j.yjmcc.2012.01.017","article-title":"Regulation of microRNA expression in the heart by the ATF6 branch of the ER stress response","volume":"52","author":"Belmont","year":"2012","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0235","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.yjmcc.2013.09.018","article-title":"Roles for ATF6 and the sarco\/endoplasmic reticulum protein quality control system in the heart","volume":"71","author":"Glembotski","year":"2014","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.yjmcc.2019.04.008_bb0240","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.37168","article-title":"Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins","volume":"7","author":"Paxman","year":"2018","journal-title":"Elife"},{"issue":"11","key":"10.1016\/j.yjmcc.2019.04.008_bb0245","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1080\/15548627.2015.1091141","article-title":"ER stress: autophagy induction, inhibition and selection","volume":"11","author":"Rashid","year":"2015","journal-title":"Autophagy"},{"issue":"1","key":"10.1016\/j.yjmcc.2019.04.008_bb0250","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cell.2007.12.018","article-title":"Autophagy in the pathogenesis of disease","volume":"132","author":"Levine","year":"2008","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.yjmcc.2019.04.008_bb0255","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/nrm4024","article-title":"Autophagy at the crossroads of catabolism and anabolism","volume":"16","author":"Kaur","year":"2015","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"5","key":"10.1016\/j.yjmcc.2019.04.008_bb0260","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.tcb.2012.02.006","article-title":"Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling","volume":"22","author":"Appenzeller-Herzog","year":"2012","journal-title":"Trends Cell Biol."},{"issue":"4","key":"10.1016\/j.yjmcc.2019.04.008_bb0265","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.3892\/ol.2015.3508","article-title":"Interplay between unfolded protein response and autophagy promotes tumor drug resistance (review)","volume":"10","author":"Yan","year":"2015","journal-title":"Oncol. Lett."},{"issue":"4","key":"10.1016\/j.yjmcc.2019.04.008_bb0270","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/aps.2014.151","article-title":"The divergent roles of autophagy in ischemia and preconditioning","volume":"36","author":"Sheng","year":"2015","journal-title":"Acta Pharmacol. Sin."},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0275","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.semcancer.2010.06.005","article-title":"Tumorigenic and adhesive properties of heparanase","volume":"20","author":"Levy-Adam","year":"2010","journal-title":"Semin. Cancer Biol."},{"issue":"4","key":"10.1016\/j.yjmcc.2019.04.008_bb0280","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1161\/01.CIR.93.4.810","article-title":"Heparin and heparan sulfate block angiotensin II-induced hypertrophy in cultured neonatal rat cardiomyocytes. A possible role of intrinsic heparin-like molecules in regulation of cardiomyocyte hypertrophy","volume":"93","author":"Akimoto","year":"1996","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.yjmcc.2019.04.008_bb0285","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0034313","article-title":"Heparanase affects food intake and regulates energy balance in mice","volume":"7","author":"Karlsson-Lindahl","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.yjmcc.2019.04.008_bb0290","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1096\/fj.03-0572com","article-title":"Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior","volume":"18","author":"Zcharia","year":"2004","journal-title":"FASEB J."}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282818312835?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282818312835?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:21:39Z","timestamp":1777418499000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282818312835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":58,"alternative-id":["S0022282818312835"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2019.04.008","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Heparanase protects the heart against chemical or ischemia\/reperfusion injury","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2019.04.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}