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Anat."},{"issue":"4","key":"10.1016\/j.yjmcc.2019.06.002_bb0355","first-page":"202","article-title":"Cells in peripheral leg lymph of normal men","volume":"11","author":"Sokolowski","year":"1978","journal-title":"Lymphology"},{"issue":"5","key":"10.1016\/j.yjmcc.2019.06.002_bb0360","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/0738-081X(95)00087-V","article-title":"Immune cell traffic from blood through the normal human skin to lymphatics","volume":"13","author":"Olszewski","year":"1995","journal-title":"Clin. Dermatol."},{"issue":"6","key":"10.1016\/j.yjmcc.2019.06.002_bb0365","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1007\/s00418-008-0525-5","article-title":"Developmental and pathological lymphangiogenesis: from models to human disease","volume":"130","author":"Maby-El Hajjami","year":"2008","journal-title":"Histochem. 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