{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T05:04:08Z","timestamp":1789448648036,"version":"build-2803163510"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZIA HL006059"],"award-info":[{"award-number":["ZIA HL006059"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZIA HL002066"],"award-info":[{"award-number":["ZIA HL002066"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL136496"],"award-info":[{"award-number":["R01HL136496"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32ES0741"],"award-info":[{"award-number":["T32ES0741"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.yjmcc.2019.09.008","type":"journal-article","created":{"date-parts":[[2019,9,16]],"date-time":"2019-09-16T10:59:28Z","timestamp":1568631568000},"page":"95-101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["A knock-in mutation at cysteine 144 of TRIM72 is cardioprotective and reduces myocardial TRIM72 release"],"prefix":"10.1016","volume":"136","author":[{"given":"Natasha","family":"Fillmore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin M.","family":"Casin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prithvi","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhui","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanley","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Boylston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Noguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangshuo","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6034-5962","authenticated-orcid":false,"given":"Mark J.","family":"Kohr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.yjmcc.2019.09.008_bb0005","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.yjmcc.2014.01.010","article-title":"S-nitrosylation of TRIM72 at cysteine 144 is critical for protection against oxidation-induced protein degradation and cell death","volume":"69","author":"Kohr","year":"2014","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0010","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1161\/CIRCRESAHA.110.232173","article-title":"Simultaneous measurement of protein oxidation and S-nitrosylation during preconditioning and ischemia\/reperfusion injury with resin-assisted capture","volume":"108","author":"Kohr","year":"2011","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0015","doi-asserted-by":"crossref","first-page":"40184","DOI":"10.1074\/jbc.M111.243469","article-title":"Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore","volume":"286","author":"Nguyen","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0020","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1161\/CIRCRESAHA.107.155879","article-title":"Preconditioning results in S-nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport","volume":"101","author":"Sun","year":"2007","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0025","doi-asserted-by":"crossref","first-page":"H505","DOI":"10.1152\/ajpheart.00681.2015","article-title":"Characterization of the sex-dependent myocardial S-nitrosothiol proteome","volume":"310","author":"Shao","year":"2016","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0030","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.115.002251","article-title":"Molecular signature of nitroso-redox balance in idiopathic dilated cardiomyopathies","volume":"4","author":"Menazza","year":"2015","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0035","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1161\/CIRCRESAHA.112.271320","article-title":"Measurement of S-nitrosylation occupancy in the myocardium with cysteine-reactive tandem mass tags: short communication","volume":"111","author":"Kohr","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0040","doi-asserted-by":"crossref","first-page":"H1327","DOI":"10.1152\/ajpheart.00997.2010","article-title":"Characterization of potential S-nitrosylation sites in the myocardium","volume":"300","author":"Kohr","year":"2011","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0045","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/ncb1812","article-title":"MG53 nucleates assembly of cell membrane repair machinery","volume":"11","author":"Cai","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0050","doi-asserted-by":"crossref","first-page":"3314","DOI":"10.1074\/jbc.M808866200","article-title":"MG53 regulates membrane budding and exocytosis in muscle cells","volume":"284","author":"Cai","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0055","doi-asserted-by":"crossref","first-page":"225","DOI":"10.4161\/cib.2.3.8077","article-title":"Mitsugumin 53 (MG53) facilitates vesicle trafficking in striated muscle to contribute to cell membrane repair","volume":"2","author":"Weisleder","year":"2009","journal-title":"Commun. Integr. Biol."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0060","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1161\/CIRCULATIONAHA.110.954628","article-title":"MG53 constitutes a primary determinant of cardiac ischemic preconditioning","volume":"121","author":"Cao","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0065","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1093\/cvr\/cvr029","article-title":"MG53 participates in ischaemic postconditioning through the RISK signalling pathway","volume":"91","author":"Zhang","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0070","doi-asserted-by":"crossref","first-page":"H825","DOI":"10.1152\/ajpheart.00660.2013","article-title":"Postconditioning leads to an increase in protein S-nitrosylation","volume":"306","author":"Tong","year":"2014","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0075","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1161\/CIRCULATIONAHA.114.012285","article-title":"Upregulation of MG53 induces diabetic cardiomyopathy through transcriptional activation of peroxisome proliferation-activated receptor alpha","volume":"131","author":"Liu","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0080","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/nature11834","article-title":"Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders","volume":"494","author":"Song","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0085","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms3354","article-title":"MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling","volume":"4","author":"Yi","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0090","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1038\/cdd.2010.1","article-title":"TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1","volume":"17","author":"Lee","year":"2010","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0095","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1161\/CIRCULATIONAHA.118.037216","article-title":"Glucose-sensitive Myokine\/Cardiokine MG53 regulates systemic insulin response and metabolic homeostasis","volume":"139","author":"Wu","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0100","article-title":"Effect of metabolic syndrome on mitsugumin 53 expression and function","volume":"10","author":"Ma","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0105","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.97898","article-title":"Role of a TRIM72 ADP-ribosylation cycle in myocardial injury and membrane repair","volume":"3","author":"Ishiwata-Endo","year":"2018","journal-title":"JCI Insight"},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0110","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1161\/CIRCRESAHA.118.313956","article-title":"S-Nitrosoglutathione reductase is essential for protecting the female heart from ischemia-reperfusion injury","volume":"123","author":"Casin","year":"2018","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0115","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1074\/jbc.M113.525154","article-title":"Mitsugumin 53 (MG53) ligase ubiquitinates focal adhesion kinase during skeletal myogenesis","volume":"289","author":"Nguyen","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0120","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1161\/ATVBAHA.112.245134","article-title":"Targeted focal adhesion kinase activation in cardiomyocytes protects the heart from ischemia\/reperfusion injury","volume":"32","author":"Cheng","year":"2012","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0125","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.113.000457","article-title":"Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine hearts","volume":"2","author":"Perricone","year":"2013","journal-title":"J. Am. Heart Assoc."},{"key":"10.1016\/j.yjmcc.2019.09.008_bb0135","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/CIRCRESAHA.109.215822","article-title":"Cardioprotection of ischemia\/reperfusion injury by cholesterol-dependent MG53-mediated membrane repair","volume":"107","author":"Wang","year":"2010","journal-title":"Circ. Res."}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282819301907?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282819301907?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T23:00:38Z","timestamp":1778626838000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282819301907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":26,"alternative-id":["S0022282819301907"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2019.09.008","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A knock-in mutation at cysteine 144 of TRIM72 is cardioprotective and reduces myocardial TRIM72 release","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2019.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}