{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:43:04Z","timestamp":1777624984281,"version":"3.51.4"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100007670","name":"Dalhousie Medical Research Foundation","doi-asserted-by":"publisher","award":["394140"],"award-info":[{"award-number":["394140"]}],"id":[{"id":"10.13039\/100007670","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["-135230"],"award-info":[{"award-number":["-135230"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1016\/j.yjmcc.2020.09.001","type":"journal-article","created":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T10:58:40Z","timestamp":1599908320000},"page":"15-26","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Increased mast cell density is associated with decreased fibrosis in human atrial tissue"],"prefix":"10.1016","volume":"149","author":[{"given":"Stephanie A.","family":"Legere","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian D.","family":"Haidl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathieu C.","family":"Castonguay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith R.","family":"Brunt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Fran\u00e7ois","family":"L\u00e9gar\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean S.","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.yjmcc.2020.09.001_bb0005","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s00018-013-1349-6","article-title":"The pathogenesis of cardiac fibrosis","volume":"71","author":"Kong","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0010","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1161\/CIRCULATIONAHA.114.008788","article-title":"Immune cell and other noncardiomyocyte regulation of cardiac hypertrophy and remodeling","volume":"131","author":"Frieler","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0015","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1161\/CIRCRESAHA.116.303577","article-title":"The biological basis for cardiac repair after myocardial infarction","volume":"119","author":"Prabhu","year":"2016","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0020","doi-asserted-by":"crossref","DOI":"10.1007\/s00395-018-0686-x","article-title":"Mapping macrophage polarization over the myocardial infarction time continuum","volume":"113","author":"Mouton","year":"2018","journal-title":"Basic Res. Cardiol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0025","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1038\/s41467-019-14263-2","article-title":"Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair","volume":"11","author":"Sim\u00f5es","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0030","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.jaci.2018.01.034","article-title":"Mast cells signal their importance in health and disease","volume":"142","author":"Olivera","year":"2018","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0035","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/imr.12634","article-title":"Mast cells as sources of cytokines, chemokines, and growth factors","volume":"282","author":"Mukai","year":"2018","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0040","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.yjmcc.2011.01.019","article-title":"The novel role of mast cells in the microenvironment of acute myocardial infarction","volume":"50","author":"Kwon","year":"2011","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0045","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1097\/00004872-200310000-00022","article-title":"A role for cardiac mast cells in the pathogenesis of hypertensive heart disease","volume":"21","author":"Shiota","year":"2003","journal-title":"J. Hypertens."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0050","doi-asserted-by":"crossref","first-page":"580","DOI":"10.3389\/fimmu.2019.00580","article-title":"Mast cells in cardiac fibrosis: new insights suggest opportunities for intervention","volume":"10","author":"Legere","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19010231","article-title":"Mast cells: key contributors to cardiac fibrosis","volume":"19","author":"Levick","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0060","doi-asserted-by":"crossref","first-page":"5467","DOI":"10.1182\/blood-2007-10-118547","article-title":"Human mast cell activation with virus-associated stimuli leads to the selective chemotaxis of natural killer cells by a CXCL8-dependent mechanism","volume":"111","author":"Burke","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0065","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/j.jaci.2015.01.042","article-title":"Respiratory syncytial virus infection of primary human mast cells induces the selective production of type i interferons, CXCL10, and CCL4","volume":"136","author":"Al-Afif","year":"2015","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0070","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.4049\/jimmunol.172.2.1227","article-title":"Prostaglandin E 2 induces degranulation-independent production of vascular endothelial growth factor by human mast cells","volume":"172","author":"Abdel-Majid","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0075","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.immuni.2017.04.017","article-title":"Mast cells are crucial for induction of group 2 innate lymphoid cells and clearance of helminth infections","volume":"46","author":"Shimokawa","year":"2017","journal-title":"Immunity"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0080","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.molimm.2018.11.009","article-title":"Distribution of mast cells within the mouse heart and its dependency on Mitf","volume":"105","author":"Ingason","year":"2019","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0085","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/01.MAT.0000150507.61120.00","article-title":"Quantitative changes in mast cell populations after left ventricular assist device implantation","volume":"51","author":"Akgul","year":"2005","journal-title":"ASAIO J."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0090","first-page":"182","article-title":"Evidence for tissue angiotensin-converting enzyme in explanted hearts of ischemic cardiomyopathy using targeted radiotracer technique","volume":"48","author":"Dilsizian","year":"2007","journal-title":"J. Nucl. Med."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0095","first-page":"63","article-title":"Morphometrical and stereological analysis of myocardial mast cells in myocarditis and dilated cardiomyopathy","volume":"45","author":"Petrovic","year":"1999","journal-title":"Folia Biol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0100","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1016\/j.transproceed.2007.06.047","article-title":"Correlation between mast cell density and myocardial fibrosis in congestive heart failure patients","volume":"39","author":"Batlle","year":"2007","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0105","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1161\/01.CIR.97.10.971","article-title":"Stem cell factor in mast cells and increased mast cell density in idiopathic and ischemic cardiomyopathy","volume":"97","author":"Patella","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0110","doi-asserted-by":"crossref","first-page":"186","DOI":"10.3389\/fphar.2017.00186","article-title":"A clinical perspective of anti-fibrotic therapies for cardiovascular disease","volume":"8","author":"Fang","year":"2017","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0115","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/imr.12625","article-title":"Changing the threshold\u2014signals and mechanisms of mast cell priming","volume":"282","author":"Halova","year":"2018","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0120","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/imr.12629","article-title":"Non-IgE mediated mast cell activation","volume":"282","author":"Redegeld","year":"2018","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0125","series-title":"Curr. Protoc. Immunol.","article-title":"Generation, isolation, and maintenance of human mast cells and mast cell lines derived from peripheral blood or cord blood","author":"R\u00e5dinger","year":"2010"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0130","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/labinvest.2010.190","article-title":"Myocardial fibrosis in response to angiotensin II is preceded by the recruitment of mesenchymal progenitor cells","volume":"91","author":"Sopel","year":"2011","journal-title":"Lab. Investig."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0135","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.ajpath.2014.11.009","article-title":"Disruption of collagen homeostasis can reverse established age-related myocardial fibrosis","volume":"185","author":"Rosin","year":"2015","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0140","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.ajpath.2014.11.027","article-title":"Nonclassical resident macrophages are important determinants in the development of myocardial fibrosis","volume":"185","author":"Falkenham","year":"2015","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0145","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1111\/j.1440-1681.2008.04930.x","article-title":"Quantification of cardiac fibrosis by colour-subtractive computer-assisted image analysis","volume":"35","author":"Gaspard","year":"2008","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0150","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1097\/PAS.0b013e31827e180b","article-title":"Surgical pathology of atrial appendages removed during the cox-maze procedure: a review of 86 cases (2004 to 2005) with implications for prognosis","volume":"37","author":"Castonguay","year":"2013","journal-title":"Am. J. Surg. Pathol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0155","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1177\/002215540104901011","article-title":"Color subtractive\u2013computer-assisted image analysis for quantification of cutaneous nerves in a diabetic mouse model","volume":"49","author":"Underwood","year":"2001","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0160","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1111\/ajt.13764","article-title":"Basophils trigger fibroblast activation in cardiac allograft fibrosis development","volume":"16","author":"Schiechl","year":"2016","journal-title":"Am. J. Transplant."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0165","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1182\/blood-2013-02-483792","article-title":"Redefinition of the human mast cell transcriptome by deep-CAGE sequencing","volume":"123","author":"Motakis","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0170","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1182\/blood.V98.4.1127","article-title":"Gene expression screening of human mast cells and eosinophils using high-density oligonucleotide probe arrays: abundant expression of major basic protein in mast cells","volume":"98","author":"Nakajima","year":"2001","journal-title":"Blood"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0175","doi-asserted-by":"crossref","DOI":"10.1126\/science.aah4573","article-title":"Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors","volume":"356","author":"Villani","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0180","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-019-02162-5","article-title":"Fibrosis independent atrial fibrillation in older patients is driven by substrate leukocyte infiltration: diagnostic and prognostic implications to patients undergoing cardiac surgery","volume":"17","author":"Aguiar","year":"2019","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0185","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1182\/blood-2015-06-650648","article-title":"Lin- CD34hi CD117int\/hi Fc\u03b5RI+ cells in human blood constitute a rare population of mast cell progenitors","volume":"127","author":"Dahlin","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0190","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1084\/jem.20160081","article-title":"Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction","volume":"213","author":"Ngkelo","year":"2016","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0195","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/imr.12626","article-title":"The controversial role of mast cells in fibrosis","volume":"282","author":"Bradding","year":"2018","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0200","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/0091-6749(87)90015-7","article-title":"Morphologically distinctive forms of cutaneous mast cell degranulation induced by cold and mechanical stimuli: an ultrastructural study","volume":"80","author":"Murphy","year":"1987","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0205","doi-asserted-by":"crossref","first-page":"113","DOI":"10.33549\/physiolres.932053","article-title":"Mast-cell degranulation induced by physical stimuli involves the activation of transient-receptor-potential channel TRPV2","volume":"61","author":"Zhang","year":"2012","journal-title":"Physiol. Res."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0210","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1053\/j.jvca.2016.03.145","article-title":"Outcomes of patients with prolonged intensive care unit length of stay after cardiac surgery","volume":"30","author":"Yu","year":"2016","journal-title":"J. Cardiothorac. Vasc. Anesth."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0215","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.jacep.2017.03.002","article-title":"Molecular and cellular mechanisms of atrial fibrosis in atrial fibrillation","volume":"3","author":"Nattel","year":"2017","journal-title":"JACC Clin. Electrophysiol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0220","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1161\/CIRCRESAHA.114.303211","article-title":"The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms","volume":"114","author":"Andrade","year":"2014","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0225","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.carpath.2007.12.003","article-title":"Association of echocardiographic atrial size and atrial fibrosis in a sequential model of congestive heart failure and atrial fibrillation","volume":"17","author":"Knackstedt","year":"2008","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0230","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1016\/j.jacc.2006.02.048","article-title":"Left atrial size. Physiologic determinants and clinical applications","volume":"47","author":"Abhayaratna","year":"2006","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0235","first-page":"233","article-title":"Atrial fibrosis: an obligatory component of arrhythmia mechanisms in atrial fibrillation?","volume":"14","author":"Platonov","year":"2017","journal-title":"J. Geriatr. Cardiol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0240","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1007\/s00436-012-2882-1","article-title":"Comparison between the collagen intensity and mast cell density in the lingual muscles and myocardium of autopsied chronic chagasic and nonchagasic patients","volume":"111","author":"Rold\u00e3o","year":"2012","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0245","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/1054-8807(96)00006-3","article-title":"Myocardial inflammatory infiltrate in human chronic chagasic cardiomyopathy: Immunohistochemical findings","volume":"5","author":"Milei","year":"1996","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0250","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/S0002-9440(10)62568-0","article-title":"Evidence for an active inflammatory process in the hibernating human myocardium","volume":"160","author":"Frangogiannis","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0255","series-title":"Postmortem Diagnosis of Anaphylaxis, in: Forensic Pathol. Rev.","first-page":"267","author":"Edston","year":"2005"},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.repc.2019.11.003","article-title":"Analysis of mast cells and myocardial fibrosis in autopsied patients with hypertensive heart disease","author":"Juliano","year":"2020","journal-title":"Rev. Port. Cardiol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0265","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1136\/ard.2004.027029","article-title":"Macrophages overloaded with tissue debris in Wegener\u2019s granulomatosis","volume":"64","author":"Mackiewicz","year":"2005","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0270","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/eurheartj\/eht099","article-title":"Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines | European heart journal | Oxford academic","volume":"36","author":"Venteclef","year":"2015","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0275","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.carpath.2008.11.001","article-title":"Atrial fibrillation is associated with cardiac hypoxia","volume":"19","author":"Gramley","year":"2010","journal-title":"Cardiovasc. Pathol."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0280","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1038\/cdd.2017.130","article-title":"Adult cardiac stem cells are multipotent and robustly myogenic: C-kit expression is necessary but not sufficient for their identification","volume":"24","author":"Vicinanza","year":"2017","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.yjmcc.2020.09.001_bb0285","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms9701","article-title":"Resident c-kit + cells in the heart are not cardiac stem cells","volume":"6","author":"Sultana","year":"2015","journal-title":"Nat. Commun."}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282820302753?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282820302753?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T23:46:58Z","timestamp":1777420018000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282820302753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":57,"alternative-id":["S0022282820302753"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2020.09.001","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Increased mast cell density is associated with decreased fibrosis in human atrial tissue","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2020.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}