{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:05:28Z","timestamp":1790697928527,"version":"4.1.0"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T00:00:00Z","timestamp":1627257600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010663","name":"European Research Council","doi-asserted-by":"publisher","award":["759248"],"award-info":[{"award-number":["759248"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["75732319"],"award-info":[{"award-number":["75732319"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB834 B12"],"award-info":[{"award-number":["SFB834 B12"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.yjmcc.2021.07.005","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T18:40:15Z","timestamp":1626892815000},"page":"111-120","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":81,"special_numbering":"C","title":["Adenosine-to-inosine Alu RNA editing controls the stability of the pro-inflammatory long noncoding RNA NEAT1 in atherosclerotic cardiovascular disease"],"prefix":"10.1016","volume":"160","author":[{"given":"Nikolaos I.","family":"Vlachogiannis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Sachse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Georgiopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleftherios","family":"Zormpas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Bampatsias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Delialis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Bonini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Galyfos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fragiska","family":"Sigala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimon","family":"Stamatelopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aikaterini","family":"Gatsiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Stellos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.yjmcc.2021.07.005_bb0005","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics-2020 update: a report from the American Heart Association","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation."},{"issue":"9","key":"10.1016\/j.yjmcc.2021.07.005_bb0010","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.jacc.2014.12.035","article-title":"Amyloid-beta (1-40) and the risk of death from cardiovascular causes in patients with coronary heart disease","volume":"65","author":"Stamatelopoulos","year":"2015","journal-title":"J. Am. Coll. Cardiol."},{"issue":"12","key":"10.1016\/j.yjmcc.2021.07.005_bb0015","doi-asserted-by":"crossref","first-page":"855","DOI":"10.7326\/M17-1540","article-title":"Amyloid-\u03b2 (1-40) and mortality in patients with non-ST-segment elevation acute coronary syndrome: a cohort study","volume":"168","author":"Stamatelopoulos","year":"2018","journal-title":"Ann. Intern. Med."},{"issue":"12","key":"10.1016\/j.yjmcc.2021.07.005_bb0020","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/nrm.2016.126","article-title":"Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression","volume":"17","author":"Engreitz","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"9","key":"10.1016\/j.yjmcc.2021.07.005_bb0025","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.it.2014.07.005","article-title":"Long non-coding RNAs in the regulation of the immune response","volume":"35","author":"Heward","year":"2014","journal-title":"Trends Immunol."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0030","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.yjmcc.2019.03.010","article-title":"RNA epigenetics and cardiovascular diseases","volume":"129","author":"Dorn","year":"2019","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"9","key":"10.1016\/j.yjmcc.2021.07.005_bb0035","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCGEN.118.001927","article-title":"Dawn of epitranscriptomic medicine","volume":"11","author":"Gatsiou","year":"2018","journal-title":"Circ. Genomic Precis. Med."},{"issue":"5","key":"10.1016\/j.yjmcc.2021.07.005_bb0040","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1093\/cvr\/cvx030","article-title":"The rise of epitranscriptomic era: implications for cardiovascular disease","volume":"113","author":"Stellos","year":"2017","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0045","doi-asserted-by":"crossref","first-page":"953","DOI":"10.3389\/fphys.2018.00953","article-title":"RNA therapeutics in cardiovascular precision medicine","volume":"9","author":"Laina","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0050","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.yjmcc.2019.03.012","article-title":"Cardiovascular inflammation: RNA takes the lead","volume":"129","author":"Martens","year":"2019","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"8","key":"10.1016\/j.yjmcc.2021.07.005_bb0055","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/nm.4135","article-title":"p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity","volume":"22","author":"Adriaens","year":"2016","journal-title":"Nat. Med."},{"issue":"6","key":"10.1016\/j.yjmcc.2021.07.005_bb0060","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.molcel.2009.01.026","article-title":"An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles","volume":"33","author":"Clemson","year":"2009","journal-title":"Mol. Cell"},{"issue":"1","key":"10.1016\/j.yjmcc.2021.07.005_bb0065","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.bbagrm.2015.06.003","article-title":"Long noncoding RNAs: re-writing dogmas of RNA processing and stability","volume":"1859","author":"Wilusz","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"issue":"3","key":"10.1016\/j.yjmcc.2021.07.005_bb0070","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.molcel.2014.01.009","article-title":"Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli","volume":"53","author":"Imamura","year":"2014","journal-title":"Mol. Cell"},{"issue":"1","key":"10.1016\/j.yjmcc.2021.07.005_bb0075","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1038\/s41467-019-09482-6","article-title":"The lncRNA Neat1 promotes activation of inflammasomes in macrophages","volume":"10","author":"Zhang","year":"2019","journal-title":"Nat. Commun."},{"issue":"37","key":"10.1016\/j.yjmcc.2021.07.005_bb0080","doi-asserted-by":"crossref","first-page":"E8660","DOI":"10.1073\/pnas.1803725115","article-title":"Long noncoding RNA NEAT1 (nuclear paraspeckle assembly transcript 1) is critical for phenotypic switching of vascular smooth muscle cells","volume":"115","author":"Ahmed","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0085","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jaut.2016.07.012","article-title":"Identification of the long noncoding RNA NEAT1 as a novel inflammatory regulator acting through MAPK pathway in human lupus","volume":"75","author":"Zhang","year":"2016","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0090","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1146\/annurev-biochem-060208-105251","article-title":"Functions and regulation of RNA editing by ADAR deaminases","volume":"79","author":"Nishikura","year":"2010","journal-title":"Annu. Rev. Biochem."},{"issue":"2","key":"10.1016\/j.yjmcc.2021.07.005_bb0095","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/nrm.2015.4","article-title":"A-to-I editing of coding and non-coding RNAs by ADARs","volume":"17","author":"Nishikura","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"9","key":"10.1016\/j.yjmcc.2021.07.005_bb0100","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1089\/ars.2017.7295","article-title":"Adenosine-to-Inosine RNA editing in health and disease","volume":"29","author":"Gatsiou","year":"2018","journal-title":"Antioxid. Redox Signal."},{"issue":"9","key":"10.1016\/j.yjmcc.2021.07.005_bb0105","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1101\/gr.2855504","article-title":"Widespread RNA editing of embedded alu elements in the human transcriptome","volume":"14","author":"Kim","year":"2004","journal-title":"Genome Res."},{"issue":"12","key":"10.1016\/j.yjmcc.2021.07.005_bb0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.0020391","article-title":"Widespread A-to-I RNA editing of Alu-containing mRNAs in the human transcriptome","volume":"2","author":"Athanasiadis","year":"2004","journal-title":"PLoS Biol."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0115","doi-asserted-by":"crossref","first-page":"102329","DOI":"10.1016\/j.jaut.2019.102329","article-title":"Increased adenosine-to-inosine RNA editing in rheumatoid arthritis","volume":"106","author":"Vlachogiannis","year":"2020","journal-title":"J. Autoimmun."},{"issue":"10","key":"10.1016\/j.yjmcc.2021.07.005_bb0120","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1038\/nm.4172","article-title":"Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation","volume":"22","author":"Stellos","year":"2016","journal-title":"Nat. Med."},{"issue":"Database issue","key":"10.1016\/j.yjmcc.2021.07.005_bb0125","doi-asserted-by":"crossref","first-page":"D79","DOI":"10.1093\/nar\/gkw835","article-title":"LNCediting: a database for functional effects of RNA editing in lncRNAs","volume":"45","author":"Gong","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0130","doi-asserted-by":"crossref","first-page":"64","DOI":"10.3389\/fbioe.2014.00064","article-title":"Uncovering RNA editing sites in long non-coding RNAs","volume":"2","author":"Picardi","year":"2014","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"38","key":"10.1016\/j.yjmcc.2021.07.005_bb0135","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1093\/eurheartj\/eht296","article-title":"2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology","volume":"34","author":"Members","year":"2013","journal-title":"Eur. Heart J."},{"issue":"20","key":"10.1016\/j.yjmcc.2021.07.005_bb0140","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1038\/emboj.2009.244","article-title":"Editing independent effects of ADARs on the miRNA\/siRNA pathways","volume":"28","author":"Heale","year":"2009","journal-title":"EMBO J."},{"issue":"3","key":"10.1016\/j.yjmcc.2021.07.005_bb0145","doi-asserted-by":"crossref","first-page":"1961","DOI":"10.1128\/jvi.70.3.1961-1968.1996","article-title":"Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase","volume":"70","author":"Liu","year":"1996","journal-title":"J. Virol."},{"issue":"6","key":"10.1016\/j.yjmcc.2021.07.005_bb0150","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1101\/gr.229102","article-title":"The human genome browser at UCSC","volume":"12","author":"Kent","year":"2002","journal-title":"Genome Res."},{"issue":"suppl_2","key":"10.1016\/j.yjmcc.2021.07.005_bb0155","article-title":"The Vienna RNA websuite","volume":"36","author":"Gruber","year":"2008","journal-title":"Nucleic Acids Res."},{"issue":"19","key":"10.1016\/j.yjmcc.2021.07.005_bb0160","doi-asserted-by":"crossref","first-page":"7287","DOI":"10.1073\/pnas.0401799101","article-title":"Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure","volume":"101","author":"Mathews","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"8","key":"10.1016\/j.yjmcc.2021.07.005_bb0165","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1261\/rna.2500605","article-title":"RNA secondary structure prediction by centroids in a Boltzmann weighted ensemble","volume":"11","author":"Ding","year":"2005","journal-title":"RNA N Y N."},{"issue":"Web Server issue","key":"10.1016\/j.yjmcc.2021.07.005_bb0170","article-title":"RBPmap: a web server for mapping binding sites of RNA-binding proteins","volume":"42","author":"Paz","year":"2014","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.yjmcc.2021.07.005_bb0175","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.molcel.2018.05.001","article-title":"Sequence, structure, and context preferences of human RNA binding proteins","volume":"70","author":"Dominguez","year":"2018","journal-title":"Mol. Cell"},{"issue":"7457","key":"10.1016\/j.yjmcc.2021.07.005_bb0180","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/nature12311","article-title":"A compendium of RNA-binding motifs for decoding gene regulation","volume":"499","author":"Ray","year":"2013","journal-title":"Nature."},{"issue":"D1","key":"10.1016\/j.yjmcc.2021.07.005_bb0185","doi-asserted-by":"crossref","first-page":"D750","DOI":"10.1093\/nar\/gkw767","article-title":"REDIportal: a comprehensive database of A-to-I RNA editing events in humans","volume":"45","author":"Picardi","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"12","key":"10.1016\/j.yjmcc.2021.07.005_bb0190","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0895-4356(96)00236-3","article-title":"A simulation study of the number of events per variable in logistic regression analysis","volume":"49","author":"Peduzzi","year":"1996","journal-title":"J. Clin. Epidemiol."},{"issue":"6917","key":"10.1016\/j.yjmcc.2021.07.005_bb0195","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nature01323","article-title":"Inflammation in atherosclerosis","volume":"420","author":"Libby","year":"2002","journal-title":"Nature."},{"issue":"4","key":"10.1016\/j.yjmcc.2021.07.005_bb0200","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1161\/CIRCRESAHA.115.306301","article-title":"Endothelial cell dysfunction and the pathobiology of atherosclerosis","volume":"118","author":"Gimbrone","year":"2016","journal-title":"Circ. Res."},{"issue":"18","key":"10.1016\/j.yjmcc.2021.07.005_bb0205","first-page":"9633","article-title":"Knockdown of NEAT1 mitigates ox-LDL-induced injury in human umbilical vein endothelial cells via miR-30c-5p\/TCF7 axis","volume":"24","author":"Guo","year":"2020","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"1","key":"10.1016\/j.yjmcc.2021.07.005_bb0210","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3892\/or.2020.7605","article-title":"NEAT1 knockdown suppresses endothelial cell proliferation and induces apoptosis by regulating miR-638\/AKT\/mTOR signaling in atherosclerosis","volume":"44","author":"Zhang","year":"2020","journal-title":"Oncol. Rep."},{"issue":"12","key":"10.1016\/j.yjmcc.2021.07.005_bb0215","doi-asserted-by":"crossref","first-page":"9361","DOI":"10.1002\/jcp.29740","article-title":"Knockdown of NEAT1 exerts suppressive effects on diabetic retinopathy progression via inactivating TGF-\u03b21 and VEGF signaling pathways","volume":"235","author":"Shao","year":"2020","journal-title":"J. Cell. Physiol."},{"issue":"5","key":"10.1016\/j.yjmcc.2021.07.005_bb0220","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1161\/ATVBAHA.110.207415","article-title":"Recent advances on the role of cytokines in atherosclerosis","volume":"31","author":"Ait-Oufella","year":"2011","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"6116","key":"10.1016\/j.yjmcc.2021.07.005_bb0225","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1126\/science.1230719","article-title":"Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure","volume":"339","author":"Swirski","year":"2013","journal-title":"Science."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0230","doi-asserted-by":"crossref","first-page":"154157","DOI":"10.1016\/j.cyto.2017.09.013","article-title":"Platelet-derived chemokines in inflammation and atherosclerosis","volume":"122","author":"Bakogiannis","year":"2017","journal-title":"Cytokine"},{"issue":"1","key":"10.1016\/j.yjmcc.2021.07.005_bb0235","doi-asserted-by":"crossref","DOI":"10.1136\/bmjdrc-2020-001821","article-title":"Circulating long non-coding RNAs NKILA, NEAT1, MALAT1, and MIAT expression and their association in type 2 diabetes mellitus","volume":"9","author":"Alfaifi","year":"2021","journal-title":"BMJ Open Diabetes Res. Care"},{"issue":"2","key":"10.1016\/j.yjmcc.2021.07.005_bb0240","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.23056","article-title":"Long noncoding RNA NEAT1 correlates with higher disease risk, worse disease condition, decreased miR-124 and miR-125a and predicts poor recurrence-free survival of acute ischemic stroke","volume":"34","author":"Li","year":"2021","journal-title":"J. Clin. Lab. Anal."},{"issue":"5","key":"10.1016\/j.yjmcc.2021.07.005_bb0245","doi-asserted-by":"crossref","DOI":"10.21037\/tcr-20-2248","article-title":"Aspirin induced long non coding RNA suppresses colon cancer growth","volume":"10","author":"Chen","year":"2021","journal-title":"Transl. Cancer Res."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0250","doi-asserted-by":"crossref","first-page":"5383","DOI":"10.1038\/ncomms6383","article-title":"The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer","volume":"5","author":"Chakravarty","year":"2014","journal-title":"Nat. Commun."},{"issue":"5","key":"10.1016\/j.yjmcc.2021.07.005_bb0255","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/nrg798","article-title":"Alu repeats and human genomic diversity","volume":"3","author":"Batzer","year":"2002","journal-title":"Nat. Rev. Genet."},{"issue":"1","key":"10.1016\/j.yjmcc.2021.07.005_bb0260","doi-asserted-by":"crossref","first-page":"5661","DOI":"10.1038\/s41467-019-13530-6","article-title":"BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance","volume":"10","author":"Wang","year":"2019","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.yjmcc.2021.07.005_bb0265","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1186\/gb-2011-12-12-236","article-title":"Alu elements: know the SINEs","volume":"12","author":"Deininger","year":"2011","journal-title":"Genome Biol."},{"issue":"6822","key":"10.1016\/j.yjmcc.2021.07.005_bb0270","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/35057062","article-title":"Initial sequencing and analysis of the human genome","volume":"409","author":"Lander","year":"2001","journal-title":"Nature."},{"issue":"9","key":"10.1016\/j.yjmcc.2021.07.005_bb0275","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1101\/gr.091827.109","article-title":"Mobile elements create structural variation: analysis of a complete human genome","volume":"19","author":"Xing","year":"2009","journal-title":"Genome Res."},{"issue":"7","key":"10.1016\/j.yjmcc.2021.07.005_bb0280","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.tcb.2017.01.002","article-title":"ALUternative regulation for gene expression","volume":"27","author":"Chen","year":"2017","journal-title":"Trends Cell Biol."},{"issue":"1","key":"10.1016\/j.yjmcc.2021.07.005_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tig.2003.11.001","article-title":"The origins and implications of Aluternative splicing","volume":"20","author":"Kreahling","year":"2004","journal-title":"Trends Genet."},{"issue":"1\u20134","key":"10.1016\/j.yjmcc.2021.07.005_bb0290","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1159\/000084968","article-title":"Human retroelements may introduce intragenic polyadenylation signals","volume":"110","author":"Roy-Engel","year":"2005","journal-title":"Cytogenet. Genome Res."},{"issue":"1","key":"10.1016\/j.yjmcc.2021.07.005_bb0295","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/1471-2164-5-97","article-title":"The association of Alu repeats with the generation of potential AU-rich elements (ARE) at 3\u2032 untranslated regions","volume":"5","author":"An","year":"2004","journal-title":"BMC Genomics"},{"issue":"11","key":"10.1016\/j.yjmcc.2021.07.005_bb0300","doi-asserted-by":"crossref","first-page":"R107","DOI":"10.1186\/gb-2012-13-11-r107","article-title":"Transposable elements reveal a stem cell-specific class of long noncoding RNAs","volume":"13","author":"Kelley","year":"2012","journal-title":"Genome Biol."},{"issue":"4","key":"10.1016\/j.yjmcc.2021.07.005_bb0305","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1003470","article-title":"Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs","volume":"9","author":"Kapusta","year":"2013","journal-title":"PLoS Genet."},{"issue":"2","key":"10.1016\/j.yjmcc.2021.07.005_bb0310","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1101\/gr.229922.117","article-title":"Ancient exapted transposable elements promote nuclear enrichment of human long noncoding RNAs","volume":"29","author":"Carlevaro-Fita","year":"2019","journal-title":"Genome Res."},{"issue":"22","key":"10.1016\/j.yjmcc.2021.07.005_bb0315","doi-asserted-by":"crossref","first-page":"7138","DOI":"10.1093\/nar\/gki1012","article-title":"AU-rich elements and associated factors: are there unifying principles?","volume":"33","author":"Barreau","year":"2005","journal-title":"Nucleic Acids Res."},{"issue":"17","key":"10.1016\/j.yjmcc.2021.07.005_bb0320","doi-asserted-by":"crossref","first-page":"2937","DOI":"10.1007\/s00018-010-0383-x","article-title":"Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements","volume":"67","author":"Khabar","year":"2010","journal-title":"Cell. Mol. Life Sci."},{"issue":"23","key":"10.1016\/j.yjmcc.2021.07.005_bb0325","doi-asserted-by":"crossref","first-page":"20700","DOI":"10.1074\/jbc.M301176200","article-title":"Nuclear import and export functions in the different isoforms of the AUF1\/heterogeneous nuclear ribonucleoprotein protein family","volume":"278","author":"Sarkar","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yjmcc.2021.07.005_bb0330","first-page":"12(10)","article-title":"De novo A-to-I RNA editing discovery in lncRNA","volume":"13","author":"Silvestris","year":"2020","journal-title":"Cancers."},{"issue":"3","key":"10.1016\/j.yjmcc.2021.07.005_bb0335","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.celrep.2013.10.002","article-title":"ADAR regulates RNA editing, transcript stability, and gene expression","volume":"5","author":"Wang","year":"2013","journal-title":"Cell Rep."},{"issue":"6","key":"10.1016\/j.yjmcc.2021.07.005_bb0340","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/nmeth.1982","article-title":"Accurate identification of human Alu and non- Alu RNA editing sites","volume":"9","author":"Ramaswami","year":"2012","journal-title":"Nat. Methods"},{"issue":"2","key":"10.1016\/j.yjmcc.2021.07.005_bb0345","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/s41587-019-0013-6","article-title":"Precise RNA editing by recruiting endogenous ADARs with antisense oligonucleotides","volume":"37","author":"Merkle","year":"2019","journal-title":"Nat. Biotechnol."}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282821001462?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282821001462?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:49:37Z","timestamp":1777387777000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282821001462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":69,"alternative-id":["S0022282821001462"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2021.07.005","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adenosine-to-inosine Alu RNA editing controls the stability of the pro-inflammatory long noncoding RNA NEAT1 in atherosclerotic cardiovascular disease","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2021.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}