{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T10:40:41Z","timestamp":1784025641132,"version":"3.55.0"},"reference-count":64,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T00:00:00Z","timestamp":1761782400000},"content-version":"am","delay-in-days":333,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association Inc","doi-asserted-by":"publisher","award":["19TPA3480072"],"award-info":[{"award-number":["19TPA3480072"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001395","name":"Wisconsin Alumni Research Foundation Inc","doi-asserted-by":"publisher","award":["AAH4884"],"award-info":[{"award-number":["AAH4884"]}],"id":[{"id":"10.13039\/100001395","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100028729","name":"American Rental Association Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100028729","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"publisher","award":["HL148733"],"award-info":[{"award-number":["HL148733"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011089","name":"University of Wisconsin Foundation","doi-asserted-by":"publisher","award":["AAH5964"],"award-info":[{"award-number":["AAH5964"]}],"id":[{"id":"10.13039\/100011089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.yjmcc.2024.10.013","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T05:48:13Z","timestamp":1730267293000},"page":"78-89","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Integrated proteomics and transcriptomics analysis reveals insights into differences in premature mortality associated with disparate pathogenic RBM20 variants"],"prefix":"10.1016","volume":"197","author":[{"given":"Zachery R.","family":"Gregorich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eli J.","family":"Larson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanghai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila U.","family":"Braz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunling","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.yjmcc.2024.10.013_bb0005","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.jacc.2009.05.038","article-title":"Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy","volume":"54","author":"Brauch","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0010","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCGEN.123.004355","article-title":"Mechanisms of RBM20 cardiomyopathy: insights from model systems","volume":"17","author":"Gregorich","year":"2024","journal-title":"Circ Genom Precis Med"},{"issue":"3","key":"10.1016\/j.yjmcc.2024.10.013_bb0015","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.118.005371","article-title":"Regional variation in RBM20 causes a highly penetrant Arrhythmogenic cardiomyopathy","volume":"12","author":"Parikh","year":"2019","journal-title":"Circ. Heart Fail."},{"issue":"3","key":"10.1016\/j.yjmcc.2024.10.013_bb0020","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCHEARTFAILURE.118.005700","article-title":"Pathogenic RBM20-variants are associated with a severe disease expression in male patients with dilated cardiomyopathy","volume":"12","author":"Hey","year":"2019","journal-title":"Circ. Heart Fail."},{"issue":"2","key":"10.1016\/j.yjmcc.2024.10.013_bb0025","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00392-016-1033-6","article-title":"Genotype-phenotype associations in dilated cardiomyopathy: meta-analysis on more than 8000 individuals","volume":"106","author":"Kayvanpour","year":"2017","journal-title":"Clin. Res. Cardiol."},{"issue":"3","key":"10.1016\/j.yjmcc.2024.10.013_bb0030","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.hrthm.2011.10.016","article-title":"Genetic variation in the alternative splicing regulator RBM20 is associated with dilated cardiomyopathy","volume":"9","author":"Refaat","year":"2012","journal-title":"Heart Rhythm."},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0035","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1038\/s41467-023-39352-1","article-title":"Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy","volume":"14","author":"Grosch","year":"2023","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0040","doi-asserted-by":"crossref","first-page":"4312","DOI":"10.1038\/s41467-023-39965-6","article-title":"Mislocalization of pathogenic RBM20 variants in dilated cardiomyopathy is caused by loss-of-interaction with Transportin-3","volume":"14","author":"Kornienko","year":"2023","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.yjmcc.2024.10.013_bb0045","doi-asserted-by":"crossref","first-page":"H1296","DOI":"10.1152\/ajpheart.00328.2022","article-title":"Deep phenotyping of two preclinical mouse models and a cohort of RBM20 mutation carriers reveals no sex-dependent disease severity in","volume":"323","author":"Lennermann","year":"2022","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"672","key":"10.1016\/j.yjmcc.2024.10.013_bb0050","doi-asserted-by":"crossref","first-page":"eade1633","DOI":"10.1126\/scitranslmed.ade1633","article-title":"Precise genomic editing of pathogenic mutations in","volume":"14","author":"Nishiyama","year":"2022","journal-title":"Sci. Transl. Med."},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0055","doi-asserted-by":"crossref","first-page":"17894","DOI":"10.1038\/s41598-020-74800-8","article-title":"A missense mutation in the RSRSP stretch of Rbm20 causes dilated cardiomyopathy and atrial fibrillation in mice","volume":"10","author":"Ihara","year":"2020","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.yjmcc.2024.10.013_bb0060","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202101811RR","article-title":"RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis","volume":"36","author":"Zhang","year":"2022","journal-title":"FASEB J."},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0065","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.yjmcc.2022.01.004","article-title":"RBM20","volume":"165","author":"Wang","year":"2022","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"11","key":"10.1016\/j.yjmcc.2024.10.013_bb0070","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1038\/s41591-020-1087-x","article-title":"Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs","volume":"26","author":"Schneider","year":"2020","journal-title":"Nat. Med."},{"issue":"10","key":"10.1016\/j.yjmcc.2024.10.013_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108117","article-title":"iPSC modeling of RBM20-deficient DCM identifies upregulation of RBM20 as a therapeutic strategy","volume":"32","author":"Briganti","year":"2020","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.yjmcc.2024.10.013_bb0080","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/cts.12393","article-title":"Pharmacological modulation of calcium homeostasis in familial dilated cardiomyopathy: an in vitro analysis from an RBM20 patient-derived iPSC model","volume":"9","author":"Wyles","year":"2016","journal-title":"Clin. Transl. Sci."},{"issue":"2","key":"10.1016\/j.yjmcc.2024.10.013_bb0085","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/hmg\/ddv468","article-title":"Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells","volume":"25","author":"Wyles","year":"2016","journal-title":"Hum. Mol. Genet."},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0090","doi-asserted-by":"crossref","first-page":"6324","DOI":"10.1038\/s41467-021-26623-y","article-title":"Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies","volume":"12","author":"Fenix","year":"2021","journal-title":"Nat. Commun."},{"issue":"13","key":"10.1016\/j.yjmcc.2024.10.013_bb0095","doi-asserted-by":"crossref","first-page":"e170001","DOI":"10.1172\/jci.insight.170001","article-title":"Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy","volume":"8","author":"Zhang","year":"2023","journal-title":"JCI Insight"},{"issue":"5","key":"10.1016\/j.yjmcc.2024.10.013_bb0100","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/nm.2693","article-title":"RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing","volume":"18","author":"Guo","year":"2012","journal-title":"Nat. Med."},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0105","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1186\/s12859-021-04344-9","article-title":"CellProfiler 4: improvements in speed, utility and usability","volume":"22","author":"Stirling","year":"2021","journal-title":"BMC Bioinformatics"},{"issue":"12","key":"10.1016\/j.yjmcc.2024.10.013_bb0110","article-title":"Automated quantification of subcellular particles in myogenic progenitors","volume":"1","author":"Filippelli","year":"2021","journal-title":"Curr Protoc"},{"issue":"8","key":"10.1016\/j.yjmcc.2024.10.013_bb0115","doi-asserted-by":"crossref","first-page":"4203","DOI":"10.1021\/acs.jproteome.1c00446","article-title":"Ultrafast and reproducible proteomics from small amounts of heart tissue enabled by azo and timsTOF pro","volume":"20","author":"Aballo","year":"2021","journal-title":"J. Proteome Res."},{"issue":"9","key":"10.1016\/j.yjmcc.2024.10.013_bb0120","doi-asserted-by":"crossref","first-page":"4922","DOI":"10.1021\/acs.analchem.7b00113","article-title":"Complete characterization of cardiac myosin heavy chain (223 kDa) enabled by size-exclusion chromatography and middle-down mass spectrometry","volume":"89","author":"Jin","year":"2017","journal-title":"Anal. Chem."},{"issue":"22","key":"10.1016\/j.yjmcc.2024.10.013_bb0125","doi-asserted-by":"crossref","first-page":"8406","DOI":"10.1002\/anie.201915374","article-title":"High-throughput proteomics enabled by a Photocleavable surfactant","volume":"59","author":"Brown","year":"2020","journal-title":"Angew. Chem. Int. Ed. Eng."},{"issue":"12","key":"10.1016\/j.yjmcc.2024.10.013_bb0130","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1074\/mcp.TIR118.000900","article-title":"Online parallel accumulation-serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer","volume":"17","author":"Meier","year":"2018","journal-title":"Mol. Cell. Proteomics"},{"issue":"12","key":"10.1016\/j.yjmcc.2024.10.013_bb0135","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1038\/nprot.2016.136","article-title":"The MaxQuant computational platform for mass spectrometry-based shotgun proteomics","volume":"11","author":"Tyanova","year":"2016","journal-title":"Nat. Protoc."},{"issue":"12","key":"10.1016\/j.yjmcc.2024.10.013_bb0140","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/nbt.1511","article-title":"MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification","volume":"26","author":"Cox","year":"2008","journal-title":"Nat. Biotechnol."},{"issue":"9","key":"10.1016\/j.yjmcc.2024.10.013_bb0145","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The Perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"Tyanova","year":"2016","journal-title":"Nat. Methods"},{"issue":"W1","key":"10.1016\/j.yjmcc.2024.10.013_bb0150","doi-asserted-by":"crossref","first-page":"W191","DOI":"10.1093\/nar\/gkz369","article-title":"G:profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)","volume":"47","author":"Raudvere","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0155","series-title":"ggplot2","author":"Wickham","year":"2016"},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0160","series-title":"The igraph software package for complex network research","author":"C. G, N. T","year":"2006"},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0165","series-title":"RStudio: Integrated Development for R","author":"R. Team","year":"2020"},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0170","series-title":"R: A Language and Environment for Statistical Computing","author":"Team","year":"2021"},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0175","series-title":"FastQC: A Quality Control Tool for High Throughput Sequence Data [Online]","author":"Andrews","year":"2010"},{"issue":"15","key":"10.1016\/j.yjmcc.2024.10.013_bb0180","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0185","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0190","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/bioinformatics\/btp616","article-title":"edgeR: a Bioconductor package for differential expression analysis of digital gene expression data","volume":"26","author":"Robinson","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0195","first-page":"289","article-title":"Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing, Wiley for the Royal Statistical Society, <cite data-v-9de00bf0=\"\">Journal of the Royal Statistical Society","author":"Benjamini","year":"1995","journal-title":"Series B (Methodological)"},{"issue":"W1","key":"10.1016\/j.yjmcc.2024.10.013_bb0200","doi-asserted-by":"crossref","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.yjmcc.2024.10.013_bb0205","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang","year":"2009","journal-title":"Nat. Protoc."},{"issue":"D1","key":"10.1016\/j.yjmcc.2024.10.013_bb0210","doi-asserted-by":"crossref","first-page":"D638","DOI":"10.1093\/nar\/gkac1000","article-title":"The STRING database in 2023: protein-protein association networks and functional enrichment analyses for any sequenced genome of interest","volume":"51","author":"Szklarczyk","year":"2023","journal-title":"Nucleic Acids Res."},{"issue":"11","key":"10.1016\/j.yjmcc.2024.10.013_bb0215","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","article-title":"Cytoscape: a software environment for integrated models of biomolecular interaction networks","volume":"13","author":"Shannon","year":"2003","journal-title":"Genome Res."},{"issue":"51","key":"10.1016\/j.yjmcc.2024.10.013_bb0220","doi-asserted-by":"crossref","first-page":"E5593","DOI":"10.1073\/pnas.1419161111","article-title":"rMATS: robust and flexible detection of differential alternative splicing from replicate RNA-Seq data","volume":"111","author":"Shen","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.yjmcc.2024.10.013_bb0225","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"issue":"7","key":"10.1016\/j.yjmcc.2024.10.013_bb0230","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"issue":"8","key":"10.1016\/j.yjmcc.2024.10.013_bb0235","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.1172\/JCI74523","article-title":"RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing","volume":"124","author":"Maatz","year":"2014","journal-title":"J. Clin. Invest."},{"issue":"6","key":"10.1016\/j.yjmcc.2024.10.013_bb0240","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1038\/nrm2694","article-title":"RNA granules: post-transcriptional and epigenetic modulators of gene expression","volume":"10","author":"Anderson","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"9","key":"10.1016\/j.yjmcc.2024.10.013_bb0245","doi-asserted-by":"crossref","first-page":"5116","DOI":"10.1073\/pnas.091062498","article-title":"Significance analysis of microarrays applied to the ionizing radiation response","volume":"98","author":"Tusher","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"2","key":"10.1016\/j.yjmcc.2024.10.013_bb0250","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1161\/CIRCGENETICS.109.904698","article-title":"Heart failure-associated changes in RNA splicing of sarcomere genes","volume":"3","author":"Kong","year":"2010","journal-title":"Circ. Cardiovasc. Genet."},{"issue":"18","key":"10.1016\/j.yjmcc.2024.10.013_bb0255","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1161\/CIRCULATIONAHA.118.036761","article-title":"Mutant KCNJ3 and KCNJ5 potassium channels as novel molecular targets in Bradyarrhythmias and atrial fibrillation","volume":"139","author":"Yamada","year":"2019","journal-title":"Circulation"},{"issue":"5","key":"10.1016\/j.yjmcc.2024.10.013_bb0260","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nrcardio.2009.44","article-title":"Sodium channel mutations and arrhythmias","volume":"6","author":"Ruan","year":"2009","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0265","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.yjmcc.2017.09.008","article-title":"Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes","volume":"113","author":"Streckfuss-B\u00f6meke","year":"2017","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"3","key":"10.1016\/j.yjmcc.2024.10.013_bb0270","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.cell.2016.03.014","article-title":"On the dependency of cellular protein levels on mRNA abundance","volume":"165","author":"Liu","year":"2016","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.yjmcc.2024.10.013_bb0275","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1038\/nrg3185","article-title":"Insights into the regulation of protein abundance from proteomic and transcriptomic analyses","volume":"13","author":"Vogel","year":"2012","journal-title":"Nat. Rev. Genet."},{"issue":"4","key":"10.1016\/j.yjmcc.2024.10.013_bb0280","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jacc.2009.02.076","article-title":"ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene","volume":"54","author":"Moulik","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"issue":"12","key":"10.1016\/j.yjmcc.2024.10.013_bb0285","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1016\/j.bbadis.2013.07.003","article-title":"Regulation of expression of atrial and brain natriuretic peptide, biomarkers for heart development and disease","volume":"1832","author":"Sergeeva","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"issue":"7838","key":"10.1016\/j.yjmcc.2024.10.013_bb0290","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/s41586-020-2797-4","article-title":"Cells of the adult human heart","volume":"588","author":"Litvi\u0148ukov\u00e1","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2024.10.013_bb0295","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1038\/s41586-024-07171-z","article-title":"Spatially organized cellular communities form the developing human heart","volume":"627","author":"Farah","year":"2024","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.yjmcc.2024.10.013_bb0300","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/j.cell.2019.11.025","article-title":"A spatiotemporal organ-wide gene expression and cell atlas of the developing human heart","volume":"179","author":"Asp","year":"2019","journal-title":"Cell"},{"issue":"5","key":"10.1016\/j.yjmcc.2024.10.013_bb0305","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1161\/CIRCULATIONAHA.119.045401","article-title":"Transcriptional and cellular diversity of the human heart","volume":"142","author":"Tucker","year":"2020","journal-title":"Circulation"},{"issue":"20","key":"10.1016\/j.yjmcc.2024.10.013_bb0310","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abf1444","article-title":"Cardiac cell type-specific gene regulatory programs and disease risk association","volume":"7","author":"Hocker","year":"2021","journal-title":"Sci. Adv."},{"issue":"7","key":"10.1016\/j.yjmcc.2024.10.013_bb0315","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1016\/j.celrep.2019.01.079","article-title":"Single-cell transcriptome analysis maps the developmental track of the human heart","volume":"26","author":"Cui","year":"2019","journal-title":"Cell Rep."},{"issue":"6518","key":"10.1016\/j.yjmcc.2024.10.013_bb0320","doi-asserted-by":"crossref","DOI":"10.1126\/science.aba7721","article-title":"A human cell atlas of fetal gene expression","volume":"370","author":"Cao","year":"2020","journal-title":"Science"}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282824001731?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282824001731?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T05:57:57Z","timestamp":1746079077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282824001731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":64,"alternative-id":["S0022282824001731"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2024.10.013","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrated proteomics and transcriptomics analysis reveals insights into differences in premature mortality associated with disparate pathogenic RBM20 variants","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2024.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}