{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T01:33:34Z","timestamp":1777685614159,"version":"3.51.4"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["SFB1002 C07"],"award-info":[{"award-number":["SFB1002 C07"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["SFB1002 S01"],"award-info":[{"award-number":["SFB1002 S01"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021778","name":"National Agency for the Promotion of Research Technological Development and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021778","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003947","name":"National University of La Plata","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010447","name":"Deutsches Zentrum f\u00fcr Herz-Kreislaufforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010447","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022087","name":"Illinois Nurses Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022087","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006668","name":"Fondo para la Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["PICT 2019\\u20131459"],"award-info":[{"award-number":["PICT 2019\\u20131459"]}],"id":[{"id":"10.13039\/501100006668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006668","name":"Fondo para la Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["PICT 2021\\u20130053"],"award-info":[{"award-number":["PICT 2021\\u20130053"]}],"id":[{"id":"10.13039\/501100006668","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006668","name":"Fondo para la Investigaci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","doi-asserted-by":"publisher","award":["PICT 2020\\u20131567"],"award-info":[{"award-number":["PICT 2020\\u20131567"]}],"id":[{"id":"10.13039\/501100006668","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jmmc-online.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.yjmcc.2025.02.001","type":"journal-article","created":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T10:57:51Z","timestamp":1739012271000},"page":"1-15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Cardiac hypertrophy induced by overexpression of IP3-released inositol 1, 4, 5-trisphosphate receptor-binding protein (IRBIT)"],"prefix":"10.1016","volume":"201","author":[{"given":"R.A.","family":"Di Matt\u00eda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Gallo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ciarrocchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.A.","family":"Gonano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.G.","family":"Blanco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.A.","family":"Valverde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.L.","family":"Portiansky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.M.","family":"Sommese","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Toischer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Bleckwedel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.C.","family":"Zelaray\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.A.","family":"Aiello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Orlowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.yjmcc.2025.02.001_bb0005","doi-asserted-by":"crossref","first-page":"10602","DOI":"10.1074\/jbc.M210119200","article-title":"IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor","volume":"278","author":"Ando","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0010","doi-asserted-by":"crossref","first-page":"9542","DOI":"10.1073\/pnas.0602250103","article-title":"IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+\/HCO 3- cotransporter 1 (pNBC1)","volume":"103","author":"Shirakabe","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0015","first-page":"21","article-title":"IRBIT binds to and functionally enhances the electroneutral Na + \u2212coupled bicarbonate transporters NBCn1, NDCBE and NCBE","author":"Parker","year":"2007","journal-title":"FASEB J."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0020","doi-asserted-by":"crossref","first-page":"33544","DOI":"10.1074\/jbc.M805534200","article-title":"IRBIT, inositol 1,4,5-triphosphate (IP3) receptor-binding protein released with IP3, binds Na+\/H+ exchanger NHE3 and activates NHE3 activity in response to calcium","volume":"283","author":"He","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0025","first-page":"193","article-title":"IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct","volume":"119","author":"Yang","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0030","first-page":"1","article-title":"Irbit mediates synergy between Ca2+ and cAMP signaling pathways during epithelial transport in mice","volume":"23","author":"Guo","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0035","doi-asserted-by":"crossref","first-page":"5515","DOI":"10.1073\/pnas.1503310112","article-title":"IRBIT regulates CaMKII\u03b1 activity and contributes to catecholamine homeostasis through tyrosine hydroxylase phosphorylation","volume":"112","author":"Kawaai","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0141569","article-title":"IRBIT interacts with the catalytic Core of phosphatidylinositol phosphate kinase type I\u03b1 and II\u03b1 through conserved catalytic aspartate residues","volume":"10","author":"Ando","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0045","doi-asserted-by":"crossref","first-page":"10694","DOI":"10.1074\/jbc.M807136200","article-title":"Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3\u2032 processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation","volume":"284","author":"Kiefer","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-022-11276-8","article-title":"RyR2\/IRBIT regulates insulin gene transcript, insulin content, and secretion in the insulinoma cell line INS-1","volume":"12","author":"Harvey","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0055","first-page":"5","article-title":"IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact","author":"Bonneau","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0060","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1126\/science.1251550","article-title":"IRBIT is a novel regulator of ribonucleotide reductase in higher eukaryotes","volume":"345","author":"Arnaoutov","year":"2014","journal-title":"Science (80-)"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0065","first-page":"1","article-title":"AHCYL1 is a novel biomarker for predicting prognosis and immunotherapy response in colorectal Cancer","volume":"2022","author":"Li","year":"2022","journal-title":"J. Oncol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0070","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.1073\/pnas.1618514114","article-title":"Splicing variation of long-IRBIT determines the target selectivity of IRBIT family proteins","volume":"114","author":"Kawaai","year":"2017","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0075","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1007\/s00204-015-1477-x","article-title":"Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets","volume":"89","author":"Tham","year":"2015","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0080","doi-asserted-by":"crossref","first-page":"H719","DOI":"10.1152\/ajpheart.01107.2003","article-title":"Phospholipase C gene expression, protein content, and activities in cardiac hypertrophy and heart failure due to volume overload","volume":"287","author":"Dent","year":"2004","journal-title":"Am. J. Physiol. Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0085","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1161\/01.RES.72.5.966","article-title":"Phosphatidylinositol metabolism in hypertrophic rat heart","volume":"72","author":"Kawaguchi","year":"1993","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0090","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1172\/JCI117739","article-title":"Differential regulation of two types of intracellular calcium release channels during end-stage heart failure","volume":"95","author":"Go","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0095","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1161\/01.RES.0000194329.41863.89","article-title":"Ca 2+ \/calmodulin\u2013dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum ca 2+ leak in heart failure","volume":"97","author":"Ai","year":"2005","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0100","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1161\/CIRCRESAHA.110.220038","article-title":"The IP 3 receptor regulates cardiac hypertrophy in response to select stimuli","volume":"107","author":"Nakayama","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0105","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.jacc.2019.07.076","article-title":"KLF15-Wnt\u2013dependent cardiac reprogramming up-regulates SHISA3 in the mammalian heart","volume":"74","author":"Noack","year":"2019","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0110","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.omtm.2020.01.004","article-title":"Successful transduction with AAV vectors after selective depletion of anti-AAV antibodies by Immunoadsorption","volume":"16","author":"Orlowski","year":"2020","journal-title":"Mol. Ther. - Methods Clin. Dev."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0115","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/978-1-4939-9139-6_19","article-title":"AAV vectors for efficient gene delivery to rodent hearts","volume":"1950","author":"Lopez-Gordo","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0120","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1161\/CIRCRESAHA.121.320680","article-title":"Gene therapy with the N-terminus of Junctophilin-2 improves heart failure in mice","volume":"130","author":"Wang","year":"2022","journal-title":"Circ. Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0125","first-page":"9","article-title":"In vivo Overexpression of Electrogenic Sodium\/Bicarbonate Cotransporter (NBCe1) by AAV9 Modifies the Cardiac Action Potential and the QT Interval in Mice","author":"Mattia","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0130","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/cvr\/cvaa110","article-title":"Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: A position paper of the ESC working group on myocardial function","volume":"117","author":"Zacchigna","year":"2021","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0135","first-page":"274","article-title":"Measurement of heart rate and Q-T interval in the conscious mouse","author":"Mitchell","year":"1998","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0140","article-title":"The activation of the G protein-coupled estrogen receptor (GPER) prevents and regresses cardiac hypertrophy","volume":"242","author":"Di","year":"2020","journal-title":"Life Sci."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0145","article-title":"The specific inhibition of the cardiac electrogenic sodium\/bicarbonate cotransporter leads to cardiac hypertrophy","volume":"312","author":"Di","year":"2023","journal-title":"Life Sci."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0150","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s00424-022-02678-8","article-title":"Discordant Ca2+ release in cardiac myocytes: characterization and susceptibility to pharmacological RyR2 modulation","volume":"474","author":"Sommese","year":"2022","journal-title":"Pflugers Arch. - Eur. J. Physiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0155","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1253\/circj.CJ-18-0247","article-title":"Non-\u03b2-blocking carvedilol analog, VK-II-86, prevents ouabain-induced cardiotoxicity","volume":"83","author":"Gonano","year":"2019","journal-title":"Circ. J."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0160","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fbinf.2023.1137815","article-title":"CardIAP: calcium transients confocal image analysis tool","volume":"3","author":"Velez Rueda","year":"2023","journal-title":"Front. Bioinform."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0165","first-page":"244","article-title":"Early Remodelling of perinuclear Ca2+ stores and Nucleoplasmic Ca2+ Signalling during the development of hypertrophy and heart failure","volume":"130","author":"Ljubojevic","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pbio.0030423","article-title":"Ankyrin-B coordinates the Na\/K ATPase, Na\/ca exchanger, and InsP 3 receptor in a cardiac T-tubule\/SR microdomain","volume":"3","author":"Mohler","year":"2005","journal-title":"PLoS Biol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0175","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/nature01335","article-title":"Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death","volume":"421","author":"Mohler","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0180","doi-asserted-by":"crossref","first-page":"11406","DOI":"10.1073\/pnas.0905485106","article-title":"Increased InsP3Rs in the junctional sarcoplasmic reticulum augment ca 2+ transients and arrhythmias associated with cardiac hypertrophy","volume":"106","author":"Harzheim","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0185","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1152\/ajpheart.01155.2007","article-title":"IP3 receptor-dependent Ca2+ release modulates excitation-contraction coupling in rabbit ventricular myocytes","volume":"294","author":"Domeier","year":"2008","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0190","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.258671","article-title":"Ca2+ release via InsP3Rs enhances RyR recruitment during Ca2+ transients by increasing dyadic [Ca2+] in cardiomyocytes","volume":"134","author":"Demydenko","year":"2021","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0195","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1158\/1541-7786.MCR-23-0445","article-title":"NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth","volume":"22","author":"Cai","year":"2024","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0200","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1093\/cvr\/cvs302","article-title":"Association of DJ-1\/PTEN\/AKT- and ASK1\/p38-mediated cell signalling with ischaemic cardiomyopathy","volume":"97","author":"Klawitter","year":"2013","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0030915","article-title":"Differences in MEF2 and NFAT transcriptional pathways according to human heart failure aetiology","volume":"7","author":"Cort\u00e9s","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0210","doi-asserted-by":"crossref","first-page":"4105","DOI":"10.1073\/pnas.1221410110","article-title":"Convergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK\/SPAK kinases in regulation of the Na+-HCO3- cotransporters family","volume":"110","author":"Hong","year":"2013","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0215","series-title":"IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na HCO 3 cotransporter 1 (pNBC1)","author":"Shirakabe","year":"2025"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0220","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1113\/JP279009","article-title":"Multiple acid-base and electrolyte disturbances upregulateNBCn1, NBCn2, IRBIT and L-IRBIT in the mTAL","volume":"598","author":"Wang","year":"2020","journal-title":"J. Physiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0225","first-page":"518","article-title":"Relief of autoinhibition of the electrogenic Na-HCO cotransporter NBCe1-B: role of IRBIT vs. amino-terminal truncation","volume":"302","author":"Lee","year":"2012","journal-title":"Am. J. Phys. Cell Phys."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0230","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1152\/ajpheart.00964.2006","article-title":"Enhanced activity of ventricular Na+-HCO3- cotransport in pressure overload hypertrophy","volume":"293","author":"Yamamoto","year":"2007","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0235","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1053\/j.gastro.2013.03.047","article-title":"Irbit mediates synergy between Ca2+ and cAMP signaling pathways during epithelial transport in mice","volume":"145","author":"Park","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0240","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1152\/physiol.00028.2012","article-title":"The WNK\/SPAK and IRBIT\/PP1 pathways in epithelial fluid and electrolyte transport","volume":"27","author":"Park","year":"2012","journal-title":"Physiol"},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0245","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1161\/CIRCHEARTFAILURE.112.972158","article-title":"No contribution of IP3 -R(2) to disease phenotype in models of dilated cardiomyopathy or pressure overload hypertrophy","volume":"6","author":"Cooley","year":"2013","journal-title":"Circ. Heart Fail."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0250","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.yjmcc.2023.03.015","article-title":"InsP3R-RyR channel crosstalk augments sarcoplasmic reticulum Ca2+ release and arrhythmogenic activity in post-MI pig cardiomyocytes","volume":"179","author":"Jin","year":"2023","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-017-13797-z","article-title":"Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation","volume":"7","author":"Torrealba","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0260","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1083\/jcb.201111095","article-title":"Mutual antagonism between IP3RII and miRNA-133a regulates calcium signals and cardiac hypertrophy","volume":"199","author":"Drawnel","year":"2012","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0265","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1016\/S0002-9440(10)61153-4","article-title":"Global gene expression profiling of end-stage dilated cardiomyopathy using a human cardiovascular-based cDNA microarray","volume":"160","author":"Barrans","year":"2002","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0270","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1093\/cvr\/cvu230","article-title":"Hypotonic swelling promotes nitric oxide release in cardiac ventricular myocytes: impact on swelling-induced negative inotropic effect","volume":"104","author":"Gonano","year":"2014","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0275","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/j.1476-5381.2012.01995.x","article-title":"JTV519 (K201) reduces sarcoplasmic reticulum Ca2+ leak and improves diastolic function in vitro in murine and human non-failing myocardium","volume":"167","author":"Sacherer","year":"2012","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/ajpheart.01009.2008","article-title":"Slowing of cardiomyocyte Ca 2+ release and contraction during heart failure progression in postinfarction mice","volume":"296","author":"M\u00f8rk","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.yjmcc.2025.02.001_bb0285","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.stemcr.2024.08.002","article-title":"Development of adeno-associated viral vectors targeting cardiac fibroblasts for efficient in vivo cardiac reprogramming","volume":"19","author":"Nakano","year":"2024","journal-title":"Stem Cell Rep."}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282825000227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282825000227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:52:38Z","timestamp":1777452758000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282825000227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":57,"alternative-id":["S0022282825000227"],"URL":"https:\/\/doi.org\/10.1016\/j.yjmcc.2025.02.001","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiac hypertrophy induced by overexpression of IP3-released inositol 1, 4, 5-trisphosphate receptor-binding protein (IRBIT)","name":"articletitle","label":"Article Title"},{"value":"Journal of Molecular and Cellular Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.yjmcc.2025.02.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}