{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T22:28:05Z","timestamp":1770503285795,"version":"3.49.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Methods"],"published-print":{"date-parts":[[2009,5]]},"DOI":"10.1016\/j.ymeth.2009.02.006","type":"journal-article","created":{"date-parts":[[2009,2,25]],"date-time":"2009-02-25T05:24:06Z","timestamp":1235539446000},"page":"3-7","source":"Crossref","is-referenced-by-count":21,"title":["The human ATR-mediated DNA damage checkpoint in a reconstituted system"],"prefix":"10.1016","volume":"48","author":[{"given":"Jun-Hyuk","family":"Choi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aziz","family":"Sancar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura A.","family":"Lindsey-Boltz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymeth.2009.02.006_bib1","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1101\/gad.914401","volume":"15","author":"Abraham","year":"2001","journal-title":"Genes Dev."},{"key":"10.1016\/j.ymeth.2009.02.006_bib2","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1146\/annurev.biochem.73.011303.073723","volume":"73","author":"Sancar","year":"2004","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ymeth.2009.02.006_bib3","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1038\/nrm2450","volume":"9","author":"Cimprich","year":"2008","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ymeth.2009.02.006_bib4","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1111\/j.1365-2443.2006.00998.x","volume":"11","author":"Hashimoto","year":"2006","journal-title":"Genes Cells"},{"key":"10.1016\/j.ymeth.2009.02.006_bib5","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1016\/j.cell.2005.12.041","volume":"124","author":"Kumagai","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.ymeth.2009.02.006_bib6","doi-asserted-by":"crossref","first-page":"18730","DOI":"10.1073\/pnas.0806621105","volume":"105","author":"Mordes","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2009.02.006_bib7","doi-asserted-by":"crossref","first-page":"35853","DOI":"10.1074\/jbc.M807435200","volume":"283","author":"Navadgi-Patil","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ymeth.2009.02.006_bib8","doi-asserted-by":"crossref","first-page":"13301","DOI":"10.1073\/pnas.0706013104","volume":"104","author":"Choi","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2009.02.006_bib9","author":"Choi","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ymeth.2009.02.006_bib10","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1126\/science.1065521","volume":"294","author":"Cortez","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.ymeth.2009.02.006_bib11","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1101\/gad.1666208","volume":"22","author":"Mordes","year":"2008","journal-title":"Genes Dev."},{"key":"10.1016\/j.ymeth.2009.02.006_bib12","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1128\/MCB.24.3.1292-1300.2003","volume":"24","author":"\u00dcnsal-Ka\u00e7maz","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ymeth.2009.02.006_bib13","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/0076-6879(83)01038-1","volume":"101","author":"Manley","year":"1983","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.ymeth.2009.02.006_bib14","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1111\/j.1432-1033.1997.00794.x","volume":"250","author":"Yamane","year":"1997","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.ymeth.2009.02.006_bib15","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.dnarep.2005.04.001","volume":"4","author":"Garcia","year":"2005","journal-title":"DNA Repair (Amst)"},{"key":"10.1016\/j.ymeth.2009.02.006_bib16","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1101\/gad.840500","volume":"14","author":"Liu","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.ymeth.2009.02.006_bib17","doi-asserted-by":"crossref","first-page":"4129","DOI":"10.1128\/MCB.21.13.4129-4139.2001","volume":"21","author":"Zhao","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ymeth.2009.02.006_bib18","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1101\/gad.842500","volume":"14","author":"Guo","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.ymeth.2009.02.006_bib19","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1021\/bi00853a029","volume":"6","author":"Kriek","year":"1967","journal-title":"Biochemistry"},{"key":"10.1016\/j.ymeth.2009.02.006_bib20","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1128\/MCB.26.1.39-49.2006","volume":"26","author":"Jiang","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ymeth.2009.02.006_bib21","doi-asserted-by":"crossref","first-page":"6673","DOI":"10.1073\/pnas.102167799","volume":"99","author":"\u00dcnsal-Ka\u00e7maz","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2009.02.006_bib22","doi-asserted-by":"crossref","first-page":"25089","DOI":"10.1074\/jbc.271.41.25089","volume":"271","author":"Gunz","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ymeth.2009.02.006_bib23","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1093\/nar\/24.5.824","volume":"24","author":"Hess","year":"1996","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ymeth.2009.02.006_bib24","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/252326a0","volume":"252","author":"Sims","year":"1974","journal-title":"Nature"},{"key":"10.1016\/j.ymeth.2009.02.006_bib25","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1126\/science.959820","volume":"193","author":"Weinstein","year":"1976","journal-title":"Science"},{"key":"10.1016\/j.ymeth.2009.02.006_bib26","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1021\/tx00011a011","volume":"2","author":"Cheng","year":"1989","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.ymeth.2009.02.006_bib27","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1038\/277410a0","volume":"277","author":"Meehan","year":"1979","journal-title":"Nature"},{"key":"10.1016\/j.ymeth.2009.02.006_bib28","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1073\/pnas.73.1.243","volume":"73","author":"Levin","year":"1976","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2009.02.006_bib29","first-page":"67","volume":"39","author":"Slaga","year":"1979","journal-title":"Cancer Res."}],"container-title":["Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046202309000292?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046202309000292?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T06:56:56Z","timestamp":1545375416000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1046202309000292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["S1046202309000292"],"URL":"https:\/\/doi.org\/10.1016\/j.ymeth.2009.02.006","relation":{},"ISSN":["1046-2023"],"issn-type":[{"value":"1046-2023","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}