{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T09:38:30Z","timestamp":1788341910045,"version":"build-2803163510"},"reference-count":42,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Methods"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.ymeth.2011.11.001","type":"journal-article","created":{"date-parts":[[2011,11,10]],"date-time":"2011-11-10T19:35:07Z","timestamp":1320953707000},"page":"415-420","source":"Crossref","is-referenced-by-count":8,"title":["Membrane proteins in four acts: Function precedes structure determination"],"prefix":"10.1016","volume":"55","author":[{"given":"W.A.","family":"Cramer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.D.","family":"Zakharov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Saif Hasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Baniulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.V.","family":"Zhalnina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.M.","family":"Soriano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Rochet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Whitelegge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Kurisu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ymeth.2011.11.001_b0005","doi-asserted-by":"crossref","first-page":"14532","DOI":"10.1073\/pnas.93.25.14532","volume":"93","author":"Landau","year":"1996","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2011.11.001_b0010","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1083\/jcb.86.1.327","volume":"86","author":"Garavito","year":"1980","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.ymeth.2011.11.001_b0015","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1146\/annurev.biochem.75.103004.142756","volume":"75","author":"Cramer","year":"2006","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ymeth.2011.11.001_b0020","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.bbabio.2011.02.006","volume":"1807","author":"Cramer","year":"2011","journal-title":"Biophys. Acta\/Bioenergetics"},{"key":"10.1016\/j.ymeth.2011.11.001_b0025","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1126\/science.1090165","volume":"302","author":"Kurisu","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.ymeth.2011.11.001_b0030","first-page":"67","volume":"103","author":"Yan","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2011.11.001_b0035","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jmb.2007.04.011","volume":"370","author":"Yamashita","year":"2007","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.ymeth.2011.11.001_b0040","doi-asserted-by":"crossref","first-page":"9861","DOI":"10.1074\/jbc.M809196200","volume":"284","author":"Baniulis","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ymeth.2011.11.001_b0045","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/nature02155","volume":"426","author":"Stroebel","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.ymeth.2011.11.001_b0050","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1146\/annurev.biochem.75.103004.142539","volume":"75","author":"Brandt","year":"2006","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ymeth.2011.11.001_b0055","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1126\/science.1123809","volume":"311","author":"Sazanov","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.ymeth.2011.11.001_b0060","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/nature09066","volume":"465","author":"Efremov","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.ymeth.2011.11.001_b0065","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1126\/science.1191046","volume":"329","author":"Hunte","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.ymeth.2011.11.001_b0070","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1399-3054.2007.00929.x","volume":"131","author":"Battchikova","year":"2007","journal-title":"Physiol. Plant."},{"key":"10.1016\/j.ymeth.2011.11.001_b0075","series-title":"Bioenergetic Processes of Cyanobacteria","first-page":"445","article-title":"Structure and Physiological Function of NDH-1 Complexes in Ctyanobacteria","author":"Battchikova","year":"2010"},{"key":"10.1016\/j.ymeth.2011.11.001_b0080","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.bbabio.2010.10.017","volume":"1807","author":"Battchikova","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.ymeth.2011.11.001_b0085","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1074\/jbc.M410914200","volume":"280","author":"Battchikova","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ymeth.2011.11.001_b0090","series-title":"Handbook of Biologically Active Peptides","article-title":"Colicins","author":"Sharma","year":"2006"},{"key":"10.1016\/j.ymeth.2011.11.001_b0095","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1038\/nsb914","volume":"10","author":"Chimento","year":"2003","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.ymeth.2011.11.001_b0100","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/j.jmb.2006.09.022","volume":"364","author":"Cherezov","year":"2006","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.ymeth.2011.11.001_b0105","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev.biochem.74.082803.133400","volume":"74","author":"Cookson","year":"2005","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ymeth.2011.11.001_b0110","doi-asserted-by":"crossref","first-page":"14369","DOI":"10.1021\/bi701275p","volume":"46","author":"Zakharov","year":"2007","journal-title":"Biochemistry \u2013 US"},{"key":"10.1016\/j.ymeth.2011.11.001_b0115","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF00015063","volume":"38","author":"Schmidt","year":"1993","journal-title":"Photosynth. Res."},{"key":"10.1016\/j.ymeth.2011.11.001_b0120","doi-asserted-by":"crossref","first-page":"5160","DOI":"10.1073\/pnas.0931431100","volume":"100","author":"Zhang","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2011.11.001_b0125","unstructured":"S.S. Hasan, E. Yamashita, C. M. Ryan, J.P. Whitelegge, W.A. Cramer, Conservation of Lipid Functions in Cytochrome bc Complexes, J. Mol. Biol., in press."},{"key":"10.1016\/j.ymeth.2011.11.001_b0130","doi-asserted-by":"crossref","first-page":"10771","DOI":"10.1021\/bi026215y","volume":"41","author":"Valiyaveetil","year":"2002","journal-title":"Biochemistry - US"},{"key":"10.1016\/j.ymeth.2011.11.001_b0135","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1073\/pnas.0510922103","volume":"103","author":"Guan","year":"2006","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.1016\/j.ymeth.2011.11.001_b0140","doi-asserted-by":"crossref","first-page":"2516","DOI":"10.1016\/j.febslet.2010.04.021","volume":"584","author":"Zickermann","year":"2010","journal-title":"FEBS Lett."},{"key":"10.1016\/j.ymeth.2011.11.001_b0145","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s11120-004-2149-5","volume":"85","author":"Cramer","year":"2005","journal-title":"Photosynth. Res."},{"key":"10.1016\/j.ymeth.2011.11.001_b0150","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1529\/biophysj.105.069609","volume":"89","author":"Kim","year":"2005","journal-title":"Biophys. J."},{"key":"10.1016\/j.ymeth.2011.11.001_b0155","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.resmic.2006.10.002","volume":"158","author":"Schneider","year":"2007","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.ymeth.2011.11.001_b0160","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1074\/mcp.M200045-MCP200","volume":"1","author":"Whitelegge","year":"2002","journal-title":"Cell Prot."},{"key":"10.1016\/j.ymeth.2011.11.001_b0165","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1021\/bi102044b","volume":"50","author":"Nowaczyk","year":"2011","journal-title":"Biochemistry - US"},{"key":"10.1016\/j.ymeth.2011.11.001_b0170","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1006\/jmbi.2000.4315","volume":"305","author":"Krogh","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.ymeth.2011.11.001_b0175","doi-asserted-by":"crossref","first-page":"D379","DOI":"10.1093\/nar\/gkp915","volume":"38","author":"Nakao","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ymeth.2011.11.001_b0180","doi-asserted-by":"crossref","first-page":"31113","DOI":"10.1074\/jbc.273.47.31113","volume":"273","author":"Taylor","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ymeth.2011.11.001_b0185","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1038\/nsb997","volume":"10","author":"Kurisu","year":"2003","journal-title":"Nat. Struct. Biol."},{"key":"10.1016\/j.ymeth.2011.11.001_b0190","doi-asserted-by":"crossref","first-page":"3880","DOI":"10.1016\/j.bpj.2010.10.029","volume":"99","author":"Spector","year":"2010","journal-title":"Biophys. J."},{"key":"10.1016\/j.ymeth.2011.11.001_b0195","doi-asserted-by":"crossref","first-page":"23163","DOI":"10.1074\/jbc.M703004200","article-title":"The outer membrane colicin translocon","volume":"282","author":"Sharma","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ymeth.2011.11.001_b0200","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1038\/emboj.2008.137","volume":"27","author":"Yamashita","year":"2008","journal-title":"EMBO J."},{"key":"10.1016\/j.ymeth.2011.11.001_b0205","doi-asserted-by":"crossref","first-page":"3901","DOI":"10.1529\/biophysj.104.046151","volume":"87","author":"Zakharov","year":"2004","journal-title":"Biophys. J."},{"key":"10.1016\/j.ymeth.2011.11.001_b0210","doi-asserted-by":"crossref","first-page":"21412","DOI":"10.1073\/pnas.1010780107","volume":"107","author":"Housden","year":"2010","journal-title":"Proc. Natl Acad. Sci. USA"}],"container-title":["Methods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046202311002337?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1046202311002337?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,28]],"date-time":"2018-11-28T12:51:19Z","timestamp":1543409479000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1046202311002337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S1046202311002337"],"URL":"https:\/\/doi.org\/10.1016\/j.ymeth.2011.11.001","relation":{},"ISSN":["1046-2023"],"issn-type":[{"value":"1046-2023","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]}}}